Research Topics
Genomes and GenesSpecies | Heinrich ReichertSummaryAffiliation: University of Basel Country: Switzerland Publications
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Detail Information
Publications
Identification and analysis of a glutamatergic local interneuron lineage in the adult Drosophila olfactory systemAbhijit Das
National Centre for Biological Sciences, TIFR, UAS GKVK Campus, Bangalore 560065, India
Neural Syst Circuits 1:4. 2011..abstract:..- Drosophila olfactory local interneurons and projection neurons derive from a common neuroblast lineage specified by the empty spiracles geneAbhijit Das
Department of Biological Sciences, Tata Institute of Fundamental Research, Mumbai, India
Neural Dev 3:33. 2008..While several studies have addressed the developmental mechanisms involved in specification and connectivity of olfactory receptor neurons and projection neurons in Drosophila, the local interneurons are far less well understood... - Developmental genetic evidence for a monophyletic origin of the bilaterian brainH Reichert
Institute of Zoology, Biozentrum Pharmazentrum, University of Basel, Klingelbergstrasse 50, CH 4056 Basel, Switzerland
Philos Trans R Soc Lond B Biol Sci 356:1533-44. 2001..We also preview the impact of comparative functional genomic analyses on our understanding of brain evolution... 
Hox genes and brain development in DrosophilaHeinrich Reichert
Biozentrum, University of Basel, Klingelbergstrasse 50, CH 4056 Basel, Switzerland
Adv Exp Med Biol 689:145-53. 2010..Many features of Hox gene action in Drosophila brain development are evolutionarily conserved and are manifest in brain development of vertebrates...- A tripartite organization of the urbilaterian brain: developmental genetic evidence from DrosophilaHeinrich Reichert
Institute of Zoology, Biozentrum Pharmazentrum, University of Basel, Switzerland
Brain Res Bull 66:491-4. 2005..This, in turn, implies that a tripartite organization of the embryonic brain may characterize all extant bilaterians, and thus may already have been established in the last common urbilaterian ancestor of all bilaterians... 
Drosophila neural stem cells: cell cycle control of self-renewal, differentiation, and termination in brain developmentHeinrich Reichert
University of Basel, Klingelbergstrasse 50, CH 4056 Basel, Switzerland
Results Probl Cell Differ 53:529-46. 2011..These findings in Drosophila brain development are likely to have general relevance in neural stem cell biology and may apply to cell cycle control in mammalian brain development as well...
Evolutionary conservation of otd/Otx2 transcription factor action: a genome-wide microarray analysis in DrosophilaHaiqiong Montalta-He
Institute of Zoology, Biozentrum Pharmazentrum, Klingelbergstrasse 50, University of Basel, CH 4056 Basel, Switzerland
Genome Biol 3:RESEARCH0015. 2002..This suggests that otd and Otx genes control a comparable subset of downstream target genes in either organism. Here we use quantitative transcript imaging to analyze this equivalence of otd and Otx gene action at a genomic level...- Conserved genetic mechanisms for embryonic brain patterningHeinrich Reichert
Institute of Zoology, Biocenter Pharmacenter, University of Basel, Switzerland
Int J Dev Biol 46:81-7. 2002.... - Polycomb group genes are required for neural stem cell survival in postembryonic neurogenesis of DrosophilaBruno Bello
Biozentrum, University of Basel, Klingelbergstrasse 50, CH 4056 Basel, Switzerland
Development 134:1091-9. 2007..Moreover, together with data on mammalian PcG genes, they imply that repression of aberrant reactivation of Hox genes may be a general and evolutionarily conserved role for PcG genes in CNS development... - Postembryonic development of transit amplifying neuroblast lineages in the Drosophila brainNatalya Izergina
Biozentrum, University of Basel, CH 4056 Basel, Switzerland
Neural Dev 4:44. 2009..In this report we use MARCM-based clonal analysis together with immunocytochemical labeling techniques to investigate the type and fate of neural cells generated in the DM lineages... - Hox gene cross-regulatory interactions in the embryonic brain of DrosophilaSimon G Sprecher
Institute of Zoology, Biocenter Pharmacenter University of Basel, Klingelbergstr 50, CH 4056 Basel, Switzerland
Mech Dev 121:527-36. 2004.... - An urbilaterian origin of the tripartite brain: developmental genetic insights from DrosophilaFrank Hirth
Institute of Zoology, Biozentrum Pharmazentrum, University of Basel, Klingelbergstrasse 50, CH 4056 Basel, Switzerland
Development 130:2365-73. 2003..This suggests that a tripartite organization of the embryonic brain was already established in the last common urbilaterian ancestor of protostomes and deuterostomes... - The brain tumor gene negatively regulates neural progenitor cell proliferation in the larval central brain of DrosophilaBruno Bello
Biozentrum, University of Basel, Klingelbergstrasse 50, CH 4056 Basel, Switzerland
Development 133:2639-48. 2006.... - The columnar gene vnd is required for tritocerebral neuromere formation during embryonic brain development of DrosophilaSimon G Sprecher
Biozentrum, University of Basel, CH 4056 Basel, Switzerland
Development 133:4331-9. 2006..Taken together, our results indicate that vnd is required for the genesis and proper identity specification of tritocerebral neural lineages during embryonic brain development of Drosophila... - Empty spiracles is required for the development of olfactory projection neuron circuitry in DrosophilaRobert Lichtneckert
Biozentrum, University of Basel, Basel, Switzerland
Development 135:2415-24. 2008..The finding that Drosophila ems, like its murine homologs Emx1/2, is required for the formation of olfactory circuitry implies that conserved genetic programs control olfactory system development in insects and mammals... - Cell lineage-specific expression and function of the empty spiracles gene in adult brain development of Drosophila melanogasterRobert Lichtneckert
Biozentrum, University of Basel, Klingelbergstrasse 50, CH 4056 Basel, Switzerland
Development 134:1291-300. 2007.... - ventral veins lacking is required for specification of the tritocerebrum in embryonic brain development of DrosophilaStefan Meier
Biozentrum Pharmazentrum, University of Basel, CH 4056 Basel, Switzerland
Mech Dev 123:76-83. 2006..Our results indicate that vvl acts downstream of the Hox gene lab and regulates specific aspects of neuronal differentiation within the tritocerebral neuromere during embryonic brain development of Drosophila... - Expression and function of the empty spiracles gene in olfactory sense organ development of Drosophila melanogasterSonia Sen
National Centre for Biological Sciences, Tata Institute of Fundamental Research, GKVK Campus, Bellary Road, Bangalore 560065, India
Development 137:3687-95. 2010.... - Gene expression patterns in primary neuronal clusters of the Drosophila embryonic brainSimon G Sprecher
Biozentrum, University of Basel, Basel, Switzerland
Gene Expr Patterns 7:584-95. 2007.... - Gliogenesis in Drosophila: genome-wide analysis of downstream genes of glial cells missing in the embryonic nervous systemBoris Egger
Biozentrum/Pharmazentrum, University of Basel, CH-4056 Basel, Switzerland
Development 129:3295-309. 2002.... - Coral emx-Am can substitute for Drosophila empty spiracles function in head, but not brain developmentBeate Hartmann
Biozentrum, University of Basel, Klingelbergstrasse 50, CH 4056 Basel, Switzerland
Dev Biol 340:125-33. 2010..These findings have implications for understanding the evolutionary origins of head versus brain patterning mechanisms... - Amplification of neural stem cell proliferation by intermediate progenitor cells in Drosophila brain developmentBruno C Bello
Biozentrum, University of Basel, CH 4056 Basel, Switzerland
Neural Dev 3:5. 2008..Here we investigate whether specific neural stem cell-like neuroblasts in the brain of Drosophila might also amplify neuronal proliferation by generating symmetrically dividing intermediate progenitors... - Lineage-specific cell death in postembryonic brain development of DrosophilaAbhilasha Kumar
Biozentrum, University of Basel, Basel, Switzerland
Development 136:3433-42. 2009..Based on our findings, we conclude that lineage-specific programmed cell death plays a prominent role in the generation of neuronal number and lineage diversity in the Drosophila brain... - Wingless and Hedgehog signaling pathways regulate orthodenticle and eyes absent during ocelli development in DrosophilaJorge Blanco
Biozentrum, University of Basel, Basel, Switzerland
Dev Biol 329:104-15. 2009..Hh signaling is necessary for eya activation in ocellar precursor cells and this activation is mediated by the full-length activator form of the transcription factor Cubitus interruptus... - Neuroblast lineage-specific origin of the neurons of the Drosophila larval olfactory systemAbhijit Das
National Centre for Biological Sciences, TIFR, UAS GKVK Campus, Bangalore 560065, India
Dev Biol 373:322-37. 2013..Our work will benefit functional studies of the larval olfactory circuit, and shed light on the relationship between larval and adult neurons... - Multipotent neural stem cells generate glial cells of the central complex through transit amplifying intermediate progenitors in Drosophila brain developmentGudrun Viktorin
Biozentrum, University of Basel, Klingelbergstrasse 70, Basel, Switzerland
Dev Biol 356:553-65. 2011..Moreover, they indicate that type II neuroblasts are remarkably multipotent neural stem cells that can generate both the neuronal and the glial progeny that make major contributions to one and the same complex brain structure... - Transcriptional signature of an adult brain tumor in DrosophilaThomas Loop
Institute of Zoology, Biocenter Pharmacenter, University of Basel, Klingelbergstr, 50, CH 4056 Basel, Switzerland
BMC Genomics 5:24. 2004.... - The egghead gene is required for compartmentalization in Drosophila optic lobe developmentYun Fan
Biozentrum Pharmazentrum, University of Basel, Klingelbergstrasse 50, CH 4056 Basel, Switzerland
Dev Biol 287:61-73. 2005..This finding underscores the importance of the lamina/lobula compartment boundary in R1-R6 axon targeting... - Arborization pattern of engrailed-positive neural lineages reveal neuromere boundaries in the Drosophila brain neuropilAbhilasha Kumar
Biozentrum, University of Basel, Basel, Switzerland
J Comp Neurol 517:87-104. 2009..This supports a model for neuromere-specific brain neuropil, in which a given lineage forms its proximal arborizations predominantly in the compartments that correspond to its neuromere of origin... - Anteroposterior regionalization of the brain: genetic and comparative aspectsRobert Lichtneckert
Biozentrum, University of Basel, Basel, Switzerland
Adv Exp Med Biol 628:32-41. 2008.... - Brain development in the yellow fever mosquito Aedes aegypti: a comparative immunocytochemical analysis using cross-reacting antibodies from Drosophila melanogasterKeshava Mysore
Biozentrum, University of Basel, Klinglebergstrasse 50, CH 4056 Basel, Switzerland
Dev Genes Evol 221:281-96. 2011..Taken together, this investigation forms the basis for future cellular and molecular investigations of brain development in this important disease vector... - Evolutionary conservation of mechanisms for neural regionalization, proliferation and interconnection in brain developmentHeinrich Reichert
Biozentrum, University of Basel, 4056 Basel, Switzerland
Biol Lett 5:112-6. 2009..Finally, neural identity and some complex circuit interconnections in specific brain domains appear to be comparable in vertebrates and invertebrates and may depend on similar developmental control genes... - Impressive expressions: developing a systematic database of gene-expression patterns in Drosophila embryogenesisHaiqiong Montalta-He
Institute of Zoology, Biocenter Pharmacenter, Klingelbergstrasse 50, University of Basel, CH 4056 Basel, Switzerland
Genome Biol 4:205. 2003.... - Programmed cell death in type II neuroblast lineages is required for central complex development in the Drosophila brainYanrui Jiang
Biozentrum, University of Basel, Basel, Switzerland
Neural Dev 7:3. 2012.... - Identification of the Drosophila melanogaster homolog of the human spastin geneLars Kammermeier
Institute of Zoology, Biozentrum Pharmazentrum, University of Basel, Klingelbergstrasse 50, 4056 Basel, Switzerland
Dev Genes Evol 213:412-5. 2003..Given this nervous system-specific expression, it will be important to determine if Drosophila spastin loss-of-function mutations also lead to neurodegeneration... - The labial gene is required to terminate proliferation of identified neuroblasts in postembryonic development of the Drosophila brainPhilipp A Kuert
Biozentrum, University of Basel, CH 4056 Basel, Switzerland
Biol Open 1:1006-15. 2012..Our analysis of labial function reveals a novel cell autonomous role of this Hox gene in shaping the lineage architecture of the brain during postembryonic development...