Christoph Rücker

Summary

Affiliation: University of Basel
Country: Switzerland

Publications

  1. ncbi request reprint 2D QSAR of PPARgamma agonist binding and transactivation
    Christoph Rücker
    Biocenter, University of Basel, Klingelbergstrasse 50 70, CH 4056 Basel, Switzerland
    Bioorg Med Chem 14:5178-95. 2006
  2. ncbi request reprint Sulfonylureas and glinides exhibit peroxisome proliferator-activated receptor gamma activity: a combined virtual screening and biological assay approach
    Marco Scarsi
    Biozentrum, University of Basel, Klingelbergstr 50 70, CH 4056 Basel, Switzerland
    Mol Pharmacol 71:398-406. 2007
  3. ncbi request reprint y-Randomization and its variants in QSPR/QSAR
    Christoph Rücker
    Biozentrum, University of Basel, 4056 Basel, Switzerland
    J Chem Inf Model 47:2345-57. 2007

Collaborators

Detail Information

Publications3

  1. ncbi request reprint 2D QSAR of PPARgamma agonist binding and transactivation
    Christoph Rücker
    Biocenter, University of Basel, Klingelbergstrasse 50 70, CH 4056 Basel, Switzerland
    Bioorg Med Chem 14:5178-95. 2006
    ..For gene transactivation, the functional activity of the agonists, a corresponding model for a similarly diverse compound set is of somewhat lower statistical quality...
  2. ncbi request reprint Sulfonylureas and glinides exhibit peroxisome proliferator-activated receptor gamma activity: a combined virtual screening and biological assay approach
    Marco Scarsi
    Biozentrum, University of Basel, Klingelbergstr 50 70, CH 4056 Basel, Switzerland
    Mol Pharmacol 71:398-406. 2007
    ..In addition, we provide a unified concept of the PPARgamma binding ability of seemingly disparate compound classes...
  3. ncbi request reprint y-Randomization and its variants in QSPR/QSAR
    Christoph Rücker
    Biozentrum, University of Basel, 4056 Basel, Switzerland
    J Chem Inf Model 47:2345-57. 2007
    ..Some progress also is reported toward the aim of obtaining the mean highest r2 of random pseudomodels by calculation rather than by tedious multiple simulations on random number variables...