Julien Puyal

Summary

Affiliation: University of Lausanne
Country: Switzerland

Publications

  1. doi request reprint Multiple interacting cell death mechanisms in the mediation of excitotoxicity and ischemic brain damage: a challenge for neuroprotection
    Julien Puyal
    Département des Neurosciences Fondamentales, Universite de Lausanne, Rue du Bugnon 9, 1005 Lausanne, Switzerland
    Prog Neurobiol 105:24-48. 2013
  2. doi request reprint Neuronal autophagy as a mediator of life and death: contrasting roles in chronic neurodegenerative and acute neural disorders
    Julien Puyal
    Département de Biologie Cellulaire and de Morphologie DBCM, Universite de Lausanne, Lausanne, Switzerland
    Neuroscientist 18:224-36. 2012
  3. ncbi request reprint Targeting autophagy to prevent neonatal stroke damage
    Julien Puyal
    Departement de Biologie Cellulaire et de Morphologie, University of Lausanne, Lausanne, Switzerland
    Autophagy 5:1060-1. 2009
  4. doi request reprint [The two faces of autophagy in the nervous system]
    Julien Puyal
    Département de Biologie Cellulaire et de Morphologie DBCM, Universite de Lausanne, CH 1005 Lausanne, Suisse
    Med Sci (Paris) 25:383-90. 2009
  5. doi request reprint Postischemic treatment of neonatal cerebral ischemia should target autophagy
    Julien Puyal
    Department of Cellular Biology and Morphology, University of Lausanne, Lausanne, Switzerland
    Ann Neurol 66:378-89. 2009
  6. ncbi request reprint Changes in D-serine levels and localization during postnatal development of the rat vestibular nuclei
    Julien Puyal
    Department of Cell Biology and Morphology, University of Lausanne, 1005 Lausanne, Switzerland
    J Comp Neurol 497:610-21. 2006
  7. doi request reprint Excitotoxicity-induced endocytosis mediates neuroprotection by TAT-peptide-linked JNK inhibitor
    Anne Vaslin
    Departement de Biologie Cellulaire et de Morphologie, University of Lausanne, Lausanne, Switzerland
    J Neurochem 119:1243-52. 2011
  8. doi request reprint Beclin 1-independent autophagy contributes to apoptosis in cortical neurons
    Yulia Grishchuk
    Departement de Biologie Cellulaire et de Morphologie, Universite de Lausanne, Switzerland
    Autophagy 7:1115-31. 2011
  9. doi request reprint Excitotoxicity-induced endocytosis confers drug targeting in cerebral ischemia
    Anne Vaslin
    Departement de Biologie Cellulaire et de Morphologie, University of Lausanne, Lausanne, Switzerland
    Ann Neurol 65:337-47. 2009
  10. pmc Lactate modulates the activity of primary cortical neurons through a receptor-mediated pathway
    Luigi Bozzo
    Department of Fundamental Neurosciences, University of Lausanne, Lausanne, Switzerland
    PLoS ONE 8:e71721. 2013

Collaborators

Detail Information

Publications17

  1. doi request reprint Multiple interacting cell death mechanisms in the mediation of excitotoxicity and ischemic brain damage: a challenge for neuroprotection
    Julien Puyal
    Département des Neurosciences Fondamentales, Universite de Lausanne, Rue du Bugnon 9, 1005 Lausanne, Switzerland
    Prog Neurobiol 105:24-48. 2013
    ..Finally, we discuss the implications of the multiplicity of cell death mechanisms for the design of neuroprotective strategies...
  2. doi request reprint Neuronal autophagy as a mediator of life and death: contrasting roles in chronic neurodegenerative and acute neural disorders
    Julien Puyal
    Département de Biologie Cellulaire and de Morphologie DBCM, Universite de Lausanne, Lausanne, Switzerland
    Neuroscientist 18:224-36. 2012
    ..The development of new therapeutic strategies based on the manipulation of autophagy will need to take into account these opposing roles of autophagy...
  3. ncbi request reprint Targeting autophagy to prevent neonatal stroke damage
    Julien Puyal
    Departement de Biologie Cellulaire et de Morphologie, University of Lausanne, Lausanne, Switzerland
    Autophagy 5:1060-1. 2009
    ..Using rats exposed to neonatal focal cerebral ischemia, we have shown that lysosomal and autophagic activities are increased in ischemic neurons, and have obtained strong neuroprotection by post-ischemic inhibition of autophagy...
  4. doi request reprint [The two faces of autophagy in the nervous system]
    Julien Puyal
    Département de Biologie Cellulaire et de Morphologie DBCM, Universite de Lausanne, CH 1005 Lausanne, Suisse
    Med Sci (Paris) 25:383-90. 2009
    ..The development of new therapeutic strategies based on the manipulation of autophagy will need to take into account these opposing roles of autophagy...
  5. doi request reprint Postischemic treatment of neonatal cerebral ischemia should target autophagy
    Julien Puyal
    Department of Cellular Biology and Morphology, University of Lausanne, Lausanne, Switzerland
    Ann Neurol 66:378-89. 2009
    ..To evaluate the contributions of autophagic, necrotic, and apoptotic cell death mechanisms after neonatal cerebral ischemia and hence define the most appropriate neuroprotective approach for postischemic therapy...
  6. ncbi request reprint Changes in D-serine levels and localization during postnatal development of the rat vestibular nuclei
    Julien Puyal
    Department of Cell Biology and Morphology, University of Lausanne, 1005 Lausanne, Switzerland
    J Comp Neurol 497:610-21. 2006
    ..The strong decrease of D-serine levels and the glial-to-neuronal switch suggests that D-serine may have distinct functional roles depending on the developmental stage of the vestibular network...
  7. doi request reprint Excitotoxicity-induced endocytosis mediates neuroprotection by TAT-peptide-linked JNK inhibitor
    Anne Vaslin
    Departement de Biologie Cellulaire et de Morphologie, University of Lausanne, Lausanne, Switzerland
    J Neurochem 119:1243-52. 2011
    ..This may explain promising reports of strong neuroprotection by TAT-peptides without apparent side effects, and warns that the timing of peptide administration is crucial...
  8. doi request reprint Beclin 1-independent autophagy contributes to apoptosis in cortical neurons
    Yulia Grishchuk
    Departement de Biologie Cellulaire et de Morphologie, Universite de Lausanne, Switzerland
    Autophagy 7:1115-31. 2011
    ....
  9. doi request reprint Excitotoxicity-induced endocytosis confers drug targeting in cerebral ischemia
    Anne Vaslin
    Departement de Biologie Cellulaire et de Morphologie, University of Lausanne, Lausanne, Switzerland
    Ann Neurol 65:337-47. 2009
    ....
  10. pmc Lactate modulates the activity of primary cortical neurons through a receptor-mediated pathway
    Luigi Bozzo
    Department of Fundamental Neurosciences, University of Lausanne, Lausanne, Switzerland
    PLoS ONE 8:e71721. 2013
    ..This study indicates that lactate operates a negative feedback on neuronal activity by a receptor-mediated mechanism, independent from its intracellular metabolism. ..
  11. doi request reprint Limited role of the c-Jun N-terminal kinase pathway in a neonatal rat model of cerebral hypoxia-ischemia
    Vanessa Ginet
    Division of Neonatology, Department of Pediatrics and Pediatric Surgery, University Hospital Center and University of Lausanne, Lausanne, Switzerland
    J Neurochem 108:552-62. 2009
    ..Thus, for perinatal asphyxia, D-JNKI1 can only be considered in association with other therapies...
  12. doi request reprint HDLs protect the MIN6 insulinoma cell line against tunicamycin-induced apoptosis without inhibiting ER stress and without restoring ER functionality
    Julien Puyal
    Department of Fundamental Neurosciences, University of Lausanne, Switzerland
    Mol Cell Endocrinol 381:291-301. 2013
    ..The capacity of HDLs to activate several anti-apoptotic pathways in beta cells may explain their ability to efficiently protect these cells against a variety of insults. ..
  13. pmc HDLs protect pancreatic β-cells against ER stress by restoring protein folding and trafficking
    Jannick Pétremand
    Department of Physiology, University of Lausanne, Lausanne, Switzerland
    Diabetes 61:1100-11. 2012
    ..This study identifies a cellular mechanism mediating the beneficial effect of HDLs on β-cells against ER stress-inducing factors...
  14. doi request reprint [Autophagy as a proteasomal substitute]
    Julien Puyal
    Departement de Biologie Cellulaire et de Morphologie, Universite de Lausanne, Rue du Bugnon 9, Lausanne, Switzerland
    Med Sci (Paris) 24:19-21. 2008
  15. ncbi request reprint Expression of glutamate transporters in the medial and lateral vestibular nuclei during rat postnatal development
    Gina Devau
    INSERM U432, Universite Montpellier II, CC 089, Place Eugene Bataillon, FR 34095 Montpellier Cedex 5, France
    Dev Neurosci 25:332-42. 2003
    ..These temporal and regional patterns of GLAST, GLT-1 and EAAC1 suggest that they play different roles in the maturation of glutamatergic synaptic transmission in the medial and lateral VN during postnatal development...
  16. ncbi request reprint Calcium-binding proteins map the postnatal development of rat vestibular nuclei and their vestibular and cerebellar projections
    Julien Puyal
    INSERM U432, Neurobiologie et Développement du Système Vestibulaire, Universite de Montpellier II, CP089, Montpellier 34095 Cedex 5, France
    J Comp Neurol 451:374-91. 2002
    ....
  17. pmc Developmental shift from long-term depression to long-term potentiation in the rat medial vestibular nuclei: role of group I metabotropic glutamate receptors
    Julien Puyal
    INSERM U432, University of Montpellier II, Place Eugene Bataillon, F 34095 Montpellier Cedex 5, France
    J Physiol 553:427-43. 2003
    ..These results provide the first evidence for a progressive change from LTD to LTP accompanied by a distinct maturation expression of mGluR1 and mGluR5 during the development of the MVN...