Julien Puyal

Summary

Affiliation: University of Lausanne
Country: Switzerland

Publications

  1. ncbi Neuronal autophagy as a mediator of life and death: contrasting roles in chronic neurodegenerative and acute neural disorders
    Julien Puyal
    Département de Biologie Cellulaire and de Morphologie DBCM, Universite de Lausanne, Lausanne, Switzerland
    Neuroscientist 18:224-36. 2012
  2. ncbi [The two faces of autophagy in the nervous system]
    Julien Puyal
    Département de Biologie Cellulaire et de Morphologie DBCM, Universite de Lausanne, CH 1005 Lausanne, Suisse
    Med Sci (Paris) 25:383-90. 2009
  3. ncbi Changes in D-serine levels and localization during postnatal development of the rat vestibular nuclei
    Julien Puyal
    Department of Cell Biology and Morphology, University of Lausanne, 1005 Lausanne, Switzerland
    J Comp Neurol 497:610-21. 2006
  4. ncbi Targeting autophagy to prevent neonatal stroke damage
    Julien Puyal
    Departement de Biologie Cellulaire et de Morphologie, University of Lausanne, Lausanne, Switzerland
    Autophagy 5:1060-1. 2009
  5. ncbi Postischemic treatment of neonatal cerebral ischemia should target autophagy
    Julien Puyal
    Department of Cellular Biology and Morphology, University of Lausanne, Lausanne, Switzerland
    Ann Neurol 66:378-89. 2009
  6. ncbi Excitotoxicity-induced endocytosis mediates neuroprotection by TAT-peptide-linked JNK inhibitor
    Anne Vaslin
    Departement de Biologie Cellulaire et de Morphologie, University of Lausanne, Lausanne, Switzerland
    J Neurochem 119:1243-52. 2011
  7. ncbi Beclin 1-independent autophagy contributes to apoptosis in cortical neurons
    Yulia Grishchuk
    Departement de Biologie Cellulaire et de Morphologie, Universite de Lausanne, Switzerland
    Autophagy 7:1115-31. 2011
  8. ncbi Excitotoxicity-induced endocytosis confers drug targeting in cerebral ischemia
    Anne Vaslin
    Departement de Biologie Cellulaire et de Morphologie, University of Lausanne, Lausanne, Switzerland
    Ann Neurol 65:337-47. 2009
  9. ncbi Limited role of the c-Jun N-terminal kinase pathway in a neonatal rat model of cerebral hypoxia-ischemia
    Vanessa Ginet
    Division of Neonatology, Department of Pediatrics and Pediatric Surgery, University Hospital Center and University of Lausanne, Lausanne, Switzerland
    J Neurochem 108:552-62. 2009
  10. ncbi HDLs protect pancreatic β-cells against ER stress by restoring protein folding and trafficking
    Jannick Pétremand
    Department of Physiology, University of Lausanne, Lausanne, Switzerland
    Diabetes 61:1100-11. 2012

Collaborators

Detail Information

Publications14

  1. ncbi Neuronal autophagy as a mediator of life and death: contrasting roles in chronic neurodegenerative and acute neural disorders
    Julien Puyal
    Département de Biologie Cellulaire and de Morphologie DBCM, Universite de Lausanne, Lausanne, Switzerland
    Neuroscientist 18:224-36. 2012
    ..The development of new therapeutic strategies based on the manipulation of autophagy will need to take into account these opposing roles of autophagy...
  2. ncbi [The two faces of autophagy in the nervous system]
    Julien Puyal
    Département de Biologie Cellulaire et de Morphologie DBCM, Universite de Lausanne, CH 1005 Lausanne, Suisse
    Med Sci (Paris) 25:383-90. 2009
    ..The development of new therapeutic strategies based on the manipulation of autophagy will need to take into account these opposing roles of autophagy...
  3. ncbi Changes in D-serine levels and localization during postnatal development of the rat vestibular nuclei
    Julien Puyal
    Department of Cell Biology and Morphology, University of Lausanne, 1005 Lausanne, Switzerland
    J Comp Neurol 497:610-21. 2006
    ..The strong decrease of D-serine levels and the glial-to-neuronal switch suggests that D-serine may have distinct functional roles depending on the developmental stage of the vestibular network...
  4. ncbi Targeting autophagy to prevent neonatal stroke damage
    Julien Puyal
    Departement de Biologie Cellulaire et de Morphologie, University of Lausanne, Lausanne, Switzerland
    Autophagy 5:1060-1. 2009
    ..Using rats exposed to neonatal focal cerebral ischemia, we have shown that lysosomal and autophagic activities are increased in ischemic neurons, and have obtained strong neuroprotection by post-ischemic inhibition of autophagy...
  5. ncbi Postischemic treatment of neonatal cerebral ischemia should target autophagy
    Julien Puyal
    Department of Cellular Biology and Morphology, University of Lausanne, Lausanne, Switzerland
    Ann Neurol 66:378-89. 2009
    ..To evaluate the contributions of autophagic, necrotic, and apoptotic cell death mechanisms after neonatal cerebral ischemia and hence define the most appropriate neuroprotective approach for postischemic therapy...
  6. ncbi Excitotoxicity-induced endocytosis mediates neuroprotection by TAT-peptide-linked JNK inhibitor
    Anne Vaslin
    Departement de Biologie Cellulaire et de Morphologie, University of Lausanne, Lausanne, Switzerland
    J Neurochem 119:1243-52. 2011
    ..This may explain promising reports of strong neuroprotection by TAT-peptides without apparent side effects, and warns that the timing of peptide administration is crucial...
  7. ncbi Beclin 1-independent autophagy contributes to apoptosis in cortical neurons
    Yulia Grishchuk
    Departement de Biologie Cellulaire et de Morphologie, Universite de Lausanne, Switzerland
    Autophagy 7:1115-31. 2011
    ....
  8. ncbi Excitotoxicity-induced endocytosis confers drug targeting in cerebral ischemia
    Anne Vaslin
    Departement de Biologie Cellulaire et de Morphologie, University of Lausanne, Lausanne, Switzerland
    Ann Neurol 65:337-47. 2009
    ....
  9. ncbi Limited role of the c-Jun N-terminal kinase pathway in a neonatal rat model of cerebral hypoxia-ischemia
    Vanessa Ginet
    Division of Neonatology, Department of Pediatrics and Pediatric Surgery, University Hospital Center and University of Lausanne, Lausanne, Switzerland
    J Neurochem 108:552-62. 2009
    ..Thus, for perinatal asphyxia, D-JNKI1 can only be considered in association with other therapies...
  10. ncbi HDLs protect pancreatic β-cells against ER stress by restoring protein folding and trafficking
    Jannick Pétremand
    Department of Physiology, University of Lausanne, Lausanne, Switzerland
    Diabetes 61:1100-11. 2012
    ..This study identifies a cellular mechanism mediating the beneficial effect of HDLs on β-cells against ER stress-inducing factors...
  11. ncbi [Autophagy as a proteasomal substitute]
    Julien Puyal
    , , Rue du Bugnon 9, Lausanne, Switzerland
    Med Sci (Paris) 24:19-21. 2008
  12. ncbi Expression of glutamate transporters in the medial and lateral vestibular nuclei during rat postnatal development
    Gina Devau
    INSERM U432, Universite Montpellier II, CC 089, Place Eugene Bataillon, FR 34095 Montpellier Cedex 5, France
    Dev Neurosci 25:332-42. 2003
    ..These temporal and regional patterns of GLAST, GLT-1 and EAAC1 suggest that they play different roles in the maturation of glutamatergic synaptic transmission in the medial and lateral VN during postnatal development...
  13. ncbi Calcium-binding proteins map the postnatal development of rat vestibular nuclei and their vestibular and cerebellar projections
    Julien Puyal
    INSERM U432, Neurobiologie et Développement du Système Vestibulaire, Universite de Montpellier II, CP089, Montpellier 34095 Cedex 5, France
    J Comp Neurol 451:374-91. 2002
    ....
  14. ncbi Developmental shift from long-term depression to long-term potentiation in the rat medial vestibular nuclei: role of group I metabotropic glutamate receptors
    Julien Puyal
    INSERM U432, University of Montpellier II, , F-34095 Montpellier Cedex 5, France
    J Physiol 553:427-43. 2003
    ..These results provide the first evidence for a progressive change from LTD to LTP accompanied by a distinct maturation expression of mGluR1 and mGluR5 during the development of the MVN...