Nicole M Probst Hensch

Summary

Affiliation: University of Zurich
Country: Switzerland

Publications

  1. pmc Decreased PM10 exposure attenuates age-related lung function decline: genetic variants in p53, p21, and CCND1 modify this effect
    Medea Imboden
    Department of Chronic Disease Epidemiology, Institute of Social and Preventive Medicine, University of Zurich, Sumatrastrasse 30, Zurich, Switzerland
    Environ Health Perspect 117:1420-7. 2009
  2. doi Longitudinal change of prebronchodilator spirometric obstruction and health outcomes: results from the SAPALDIA cohort
    N M Probst-Hensch
    Institute of Social and Preventive Medicine, Chronic Disease Epidemiology, University of Zurich, Sumatrastr 30, CH 8091 Zurich, Switzerland
    Thorax 65:150-6. 2010
  3. pmc Glutathione S-transferase polymorphisms, passive smoking, obesity, and heart rate variability in nonsmokers
    Nicole M Probst-Hensch
    Molecular Epidemiology Cancer Registry, University of Zurich, Zurich, Switzerland
    Environ Health Perspect 116:1494-9. 2008
  4. pmc Differences in heart rate variability associated with long-term exposure to NO2
    Denise Felber Dietrich
    Institute of Social and Preventive Medicine, University of Basel, Basel, Switzerland
    Environ Health Perspect 116:1357-61. 2008
  5. ncbi Reduced exposure to PM10 and attenuated age-related decline in lung function
    Sara H Downs
    Institute of Social and Preventive Medicine, University of Basel, Basel, Switzerland
    N Engl J Med 357:2338-47. 2007
  6. pmc Glutathione S-transferase genotypes modify lung function decline in the general population: SAPALDIA cohort study
    Medea Imboden
    Institutes of Social and Preventive Medicine and Surgical Pathology, Molecular Epidemiology Cancer Registry, University of Zurich and University Hospital Zurich, Switzerland
    Respir Res 8:2. 2007
  7. ncbi The effect of the cyclin D1 (CCND1) A870G polymorphism on colorectal cancer risk is modified by glutathione-S-transferase polymorphisms and isothiocyanate intake in the Singapore Chinese Health Study
    Nicole M Probst-Hensch
    Molecular Epidemiology Cancer Registry, Institutes of Social and Preventive Medicine Surgical Pathology, University Hospital Zurich Zurich, Switzerland
    Carcinogenesis 27:2475-82. 2006
  8. pmc Effect of physical activity on heart rate variability in normal weight, overweight and obese subjects: results from the SAPALDIA study
    Denise Felber Dietrich
    Institute of Social and Preventive Medicine, University of Basel, Steinengraben 49, 4051 Basel, Switzerland
    Eur J Appl Physiol 104:557-65. 2008
  9. pmc Circulating alpha1-antitrypsin in the general population: determinants and association with lung function
    Oliver Senn
    Molecular Epidemiology Cancer Registry, Institutes of Social and Preventive Medicine and Clinical Pathology, University of Zurich, Zurich, Switzerland
    Respir Res 9:35. 2008
  10. ncbi Epidemiology and pathophysiology of obesity as cause of cancer
    Michela Ceschi
    Molecular Epidemiology, Institute of Social and Preventive Medicine, University of Zurich, University Hospital, Vogelsangstrasse 10, CH 8091 Zurich, Switzerland
    Swiss Med Wkly 137:50-6. 2007

Collaborators

Detail Information

Publications11

  1. pmc Decreased PM10 exposure attenuates age-related lung function decline: genetic variants in p53, p21, and CCND1 modify this effect
    Medea Imboden
    Department of Chronic Disease Epidemiology, Institute of Social and Preventive Medicine, University of Zurich, Sumatrastrasse 30, Zurich, Switzerland
    Environ Health Perspect 117:1420-7. 2009
    ..Recent evidence points to the involvement of the genes p53 and p21 and of the cell cycle control gene cyclin D1 (CCND1) in the response of bronchial cells to air pollution...
  2. doi Longitudinal change of prebronchodilator spirometric obstruction and health outcomes: results from the SAPALDIA cohort
    N M Probst-Hensch
    Institute of Social and Preventive Medicine, Chronic Disease Epidemiology, University of Zurich, Sumatrastr 30, CH 8091 Zurich, Switzerland
    Thorax 65:150-6. 2010
    ..In the SAPALDIA (Swiss Study on Air Pollution and Lung Disease in Adults) cohort, time course, clinical relevance and determinants of severity stages of obstruction were investigated using prebronchodilator spirometry...
  3. pmc Glutathione S-transferase polymorphisms, passive smoking, obesity, and heart rate variability in nonsmokers
    Nicole M Probst-Hensch
    Molecular Epidemiology Cancer Registry, University of Zurich, Zurich, Switzerland
    Environ Health Perspect 116:1494-9. 2008
    ..Disturbances of heart rate variability (HRV) may represent one pathway by which second-hand smoke (SHS) and air pollutants affect cardiovascular morbidity and mortality. The mechanisms are poorly understood...
  4. pmc Differences in heart rate variability associated with long-term exposure to NO2
    Denise Felber Dietrich
    Institute of Social and Preventive Medicine, University of Basel, Basel, Switzerland
    Environ Health Perspect 116:1357-61. 2008
    ..Short-term studies have shown that subjects exposed to higher traffic-associated air pollutant levels have lower HRV...
  5. ncbi Reduced exposure to PM10 and attenuated age-related decline in lung function
    Sara H Downs
    Institute of Social and Preventive Medicine, University of Basel, Basel, Switzerland
    N Engl J Med 357:2338-47. 2007
    ..Air pollution has been associated with impaired health, including reduced lung function in adults. Moving to cleaner areas has been shown to attenuate adverse effects of air pollution on lung function in children but not in adults...
  6. pmc Glutathione S-transferase genotypes modify lung function decline in the general population: SAPALDIA cohort study
    Medea Imboden
    Institutes of Social and Preventive Medicine and Surgical Pathology, Molecular Epidemiology Cancer Registry, University of Zurich and University Hospital Zurich, Switzerland
    Respir Res 8:2. 2007
    ..In the present study, we assessed whether low activity variants in GST genes are also associated with accelerated lung function decline in the general adult population...
  7. ncbi The effect of the cyclin D1 (CCND1) A870G polymorphism on colorectal cancer risk is modified by glutathione-S-transferase polymorphisms and isothiocyanate intake in the Singapore Chinese Health Study
    Nicole M Probst-Hensch
    Molecular Epidemiology Cancer Registry, Institutes of Social and Preventive Medicine Surgical Pathology, University Hospital Zurich Zurich, Switzerland
    Carcinogenesis 27:2475-82. 2006
    ..The results of our current study on CRC and those of our previous breast cancer study are compatible with the notion of oxidative stress in target cells as important determinant of direction and magnitude of the CCND1 effect...
  8. pmc Effect of physical activity on heart rate variability in normal weight, overweight and obese subjects: results from the SAPALDIA study
    Denise Felber Dietrich
    Institute of Social and Preventive Medicine, University of Basel, Steinengraben 49, 4051 Basel, Switzerland
    Eur J Appl Physiol 104:557-65. 2008
    ..Regular physical exercise has strong beneficial effects on cardiac autonomic nervous function and thus appears to offset the negative effect of obesity on HRV...
  9. pmc Circulating alpha1-antitrypsin in the general population: determinants and association with lung function
    Oliver Senn
    Molecular Epidemiology Cancer Registry, Institutes of Social and Preventive Medicine and Clinical Pathology, University of Zurich, Zurich, Switzerland
    Respir Res 9:35. 2008
    ..Less is known about the respiratory health impact of variation in AAT serum concentrations in the general population. We cross-sectionally investigated correlates of circulating AAT concentrations and its association with FEV1...
  10. ncbi Epidemiology and pathophysiology of obesity as cause of cancer
    Michela Ceschi
    Molecular Epidemiology, Institute of Social and Preventive Medicine, University of Zurich, University Hospital, Vogelsangstrasse 10, CH 8091 Zurich, Switzerland
    Swiss Med Wkly 137:50-6. 2007
    ..Since evidence is mounting that excess body weight can also adversely affect cancer prognosis, obesity is a primary target for cancer control programs...
  11. ncbi Follow-up of the Swiss Cohort Study on Air Pollution and Lung Diseases in Adults (SAPALDIA 2) 1991-2003: methods and characterization of participants
    Ursula Ackermann-Liebrich
    Institute of Social and Preventive Medicine, University of Basel, Switzerland
    Soz Praventivmed 50:245-63. 2005
    ..The Swiss Cohort Study on Air Pollution and Lung Diseases in Adults (SAPALDIA) was designed to investigate the health effects from long-term exposure to air pollution...