Klara M Posfay-Barbe

Summary

Affiliation: University Hospital
Country: Switzerland

Publications

  1. pmc Diagnosis of whooping cough in Switzerland: differentiating Bordetella pertussis from Bordetella holmesii by polymerase chain reaction
    Laure F Pittet
    Department of Paediatrics, Division of General Paediatrics, Children s Hospital, University Hospitals of Geneva, Geneva, Switzerland
    PLoS ONE 9:e88936. 2014
  2. doi request reprint Parental functioning improves the developmental quotient of pediatric liver transplant recipients
    Klara M Posfay-Barbe
    Department of Pediatrics, Children s Hospital of Geneva, University Hospitals of Geneva, 6 Rue Willy Donze, Geneva, Switzerland
    Pediatr Transplant 17:355-61. 2013
  3. doi request reprint Varicella-zoster immunization in pediatric liver transplant recipients: safe and immunogenic
    K M Posfay-Barbe
    Department of Pediatrics, Division of General Pediatrics, Children s Hospital of Geneva, University Hospitals of Geneva, Switzerland
    Am J Transplant 12:2974-85. 2012
  4. doi request reprint Infections in pediatrics: old and new diseases
    Klara M Posfay-Barbe
    Children s Hospital of Geneva, University Hospitals of Geneva, Switzerland
    Swiss Med Wkly 142:w13654. 2012
  5. ncbi request reprint [Recurrent lower respiratory tract infection in children: when and how should they be investigated?]
    K M Posfay Barbe
    Departement de Pediatrie, Hopital des Enfants, Hopitaux Universitaires de Geneve, 1211 Geneve 14
    Rev Med Suisse 1:493-8. 2005
  6. doi request reprint Immunity to pneumococcal surface proteins in children with community-acquired pneumonia: a distinct pattern of responses to pneumococcal choline-binding protein A
    K M Posfay-Barbe
    Departments of Child and Adolescent Medicine and Pathology Immunology, University of Geneva, Geneva, Switzerland
    Clin Microbiol Infect 17:1232-8. 2011
  7. doi request reprint Listeriosis
    Klara M Posfay-Barbe
    Department of Pediatrics, Children s Hospital of Geneva, University Hospitals of Geneva, 6 Rue Willy Donze, 1211 Geneva 14, Switzerland
    Semin Fetal Neonatal Med 14:228-33. 2009
  8. doi request reprint Immunization and transplantation--what is new and what is coming?
    Klara M Posfay-Barbe
    Department of Pediatrics and Adolescent Medicine, Children s Hospital of Geneva, University Hospitals of Geneva, Switzerland
    Pediatr Transplant 13:404-10. 2009
  9. doi request reprint Food poisoning as a cause of acute liver failure
    Klara M Posfay-Barbe
    Division of Pediatrics, Department of Pediatrics, Children s Hospital of Geneva, Geneva, Switzerland
    Pediatr Infect Dis J 27:846-7. 2008
  10. ncbi request reprint [Whooping cough: a diagnosis one shouldn't forget]
    K M Posfay-Barbe
    Service et Département de pédiatrie Maladies infectieuses pédiatriques, Hôpital des enfants HUG, 1211 Geneve 14
    Rev Med Suisse 2:503-6, 509-11. 2006

Collaborators

Detail Information

Publications35

  1. pmc Diagnosis of whooping cough in Switzerland: differentiating Bordetella pertussis from Bordetella holmesii by polymerase chain reaction
    Laure F Pittet
    Department of Paediatrics, Division of General Paediatrics, Children s Hospital, University Hospitals of Geneva, Geneva, Switzerland
    PLoS ONE 9:e88936. 2014
    ..holmesii seems to be circulating less than in neighboring countries and that specific diagnostic procedures are not necessary routinely. However, as the epidemiological situation may change rapidly, periodic reevaluation is suggested. ..
  2. doi request reprint Parental functioning improves the developmental quotient of pediatric liver transplant recipients
    Klara M Posfay-Barbe
    Department of Pediatrics, Children s Hospital of Geneva, University Hospitals of Geneva, 6 Rue Willy Donze, Geneva, Switzerland
    Pediatr Transplant 17:355-61. 2013
    ..03). Paternal performance scores were higher than maternal scores. Children transplanted after two yr of age suffer greater long-term deficits than those transplanted as infants...
  3. doi request reprint Varicella-zoster immunization in pediatric liver transplant recipients: safe and immunogenic
    K M Posfay-Barbe
    Department of Pediatrics, Division of General Pediatrics, Children s Hospital of Geneva, University Hospitals of Geneva, Switzerland
    Am J Transplant 12:2974-85. 2012
    ..7 years). No breakthrough disease was reported during follow-up (median 4.1 years). Thereby, VZV vaccine appears to be safe, immunogenic and provide protection against disease in pediatric LT patients...
  4. doi request reprint Infections in pediatrics: old and new diseases
    Klara M Posfay-Barbe
    Children s Hospital of Geneva, University Hospitals of Geneva, Switzerland
    Swiss Med Wkly 142:w13654. 2012
    ..This overview gives a general idea on some topics that are currently significant and specific to paediatric infectious diseases...
  5. ncbi request reprint [Recurrent lower respiratory tract infection in children: when and how should they be investigated?]
    K M Posfay Barbe
    Departement de Pediatrie, Hopital des Enfants, Hopitaux Universitaires de Geneve, 1211 Geneve 14
    Rev Med Suisse 1:493-8. 2005
    ..Finally, this article also describes an upcoming study in Switzerland which will evaluate in 2005 the clinical and immunological outcome of these young patients...
  6. doi request reprint Immunity to pneumococcal surface proteins in children with community-acquired pneumonia: a distinct pattern of responses to pneumococcal choline-binding protein A
    K M Posfay-Barbe
    Departments of Child and Adolescent Medicine and Pathology Immunology, University of Geneva, Geneva, Switzerland
    Clin Microbiol Infect 17:1232-8. 2011
    ..002) of P-CAP. Novel PSPs facilitate the demonstration of recent pneumococcal exposure in CAP children. Low anti-PcpA antibody titres at admission distinguished children with P-CAP from those with CAP with a non-pneumococcal origin...
  7. doi request reprint Listeriosis
    Klara M Posfay-Barbe
    Department of Pediatrics, Children s Hospital of Geneva, University Hospitals of Geneva, 6 Rue Willy Donze, 1211 Geneva 14, Switzerland
    Semin Fetal Neonatal Med 14:228-33. 2009
    ..Clinical manifestations of infection in the newborn fall into the traditional categories of early- and late-onset sepsis. Therapeutic recommendations include ampicillin and gentamicin for 14-21 days...
  8. doi request reprint Immunization and transplantation--what is new and what is coming?
    Klara M Posfay-Barbe
    Department of Pediatrics and Adolescent Medicine, Children s Hospital of Geneva, University Hospitals of Geneva, Switzerland
    Pediatr Transplant 13:404-10. 2009
    ..We also review less common vaccines (such as encephalitis vaccines), and possible vaccines of the future that could have an important clinical impact in these children, such as CMV or EBV vaccines...
  9. doi request reprint Food poisoning as a cause of acute liver failure
    Klara M Posfay-Barbe
    Division of Pediatrics, Department of Pediatrics, Children s Hospital of Geneva, Geneva, Switzerland
    Pediatr Infect Dis J 27:846-7. 2008
    ..As a result of rapid identification of the microorganism and supportive care, liver transplantation was avoided, and she recovered fully...
  10. ncbi request reprint [Whooping cough: a diagnosis one shouldn't forget]
    K M Posfay-Barbe
    Service et Département de pédiatrie Maladies infectieuses pédiatriques, Hôpital des enfants HUG, 1211 Geneve 14
    Rev Med Suisse 2:503-6, 509-11. 2006
    ..This strategy would not only protect these individuals from whooping cough, but most importantly protect, by herd immunity, the infants too young to be (fully) immunized...
  11. ncbi request reprint Vaccine-induced immunity in children after orthotopic liver transplantation: a 12-yr review of the Swiss national reference center
    Alessandro Diana
    Department of Pediatrics, Children s Hospital of Geneva, University Hospitals of Geneva, Switzerland
    Pediatr Transplant 11:31-7. 2007
    ....
  12. doi request reprint Determinants of vaccine immunity in the cohort of human immunodeficiency virus-infected children living in Switzerland
    Catherine Myers
    Department of Pediatrics, Geneva Medical School and University Hospitals of Geneva, Switzerland
    Pediatr Infect Dis J 28:996-1001. 2009
    ..Human immunodeficiency virus (HIV)-infected children are at increased risk of infections caused by vaccine preventable pathogens, and specific immunization recommendations have been issued...
  13. doi request reprint Comparison of clinical presentation of respiratory tract infections in H1N1/09-positive and H1N1/09-negative patients
    Pierre Alex Crisinel
    Department of Pediatrics, Children s Hospital of Geneva, University Hospitals of Geneva, Geneva 14, Switzerland
    Eur J Pediatr 171:159-66. 2012
    ..24%) and myalgias (41% vs. 20%). H1N1/09-negative patients had more wheezing episodes (29% vs. 9%), higher rates of dyspnea (28% vs. 20%) and of hospital admissions (35% vs. 16%)...
  14. doi request reprint Secular trends in antibiotic use among neonates: 2001-2008
    Walter Zingg
    Infection Control Program, University of Geneva Hospitals and Faculty of Medicine, Geneva, Switzerland
    Pediatr Infect Dis J 30:365-70. 2011
    ..Few data exist on time trends of antibiotic consumption among neonates...
  15. pmc Imipenem-resistant Nocardia cyriacigeorgica infection in a child with chronic granulomatous disease
    Andres Hagerman
    Department of Pediatrics, Children s Hospital of Geneva, University Hospital of Geneva, 6 Rue Willy Donze, 1211 Geneva, Switzerland
    J Clin Microbiol 49:1185-7. 2011
    ..We describe a patient with imipenem-resistant Nocardia cyriacigeorgica, which, to our knowledge, has not been previously reported among isolates of this species...
  16. ncbi request reprint Bordetella holmesii: an under-recognised Bordetella species
    Laure F Pittet
    Department of Paediatrics, Division of General Paediatrics, Children s Hospital, University Hospitals of Geneva, University of Geneva, Geneva, Switzerland
    Lancet Infect Dis 14:510-9. 2014
    ..B holmesii's adaptation to human beings is continuing, and virulence might increase, causing the need for better diagnostic assays and epidemiological surveillance. ..
  17. ncbi request reprint How do physicians immunize their own children? Differences among pediatricians and nonpediatricians
    Klara M Posfay-Barbe
    Centre for Vaccinology and Neonatal Immunology, Department of Pathology Immunology, University of Geneva, Switzerland
    Pediatrics 116:e623-33. 2005
    ..Physicians are known to exert a direct influence on immunization rates by answering questions and clarifying misconceptions. Yet, it is unknown how they immunize their own children...
  18. ncbi request reprint Recurrence of cardiorespiratory events following repeat DTaP-based combined immunization in very low birth weight premature infants
    Aline Flatz-Jequier
    Department of Pediatrics, Children s Hospital, University Hospitals of Geneva and Medical Faculty of the University of Geneva, Geneva, Switzerland
    J Pediatr 153:429-31. 2008
    ..A cardiorespiratory event associated with the first vaccination was the sole risk factor for recurrence identified...
  19. doi request reprint Infectious diseases in pediatric transplantation: review of the literature 2007-2008
    Arnaud G L'huillier
    Department of Pediatrics, Children s Hospital of Geneva, University Hospitals of Geneva, Switzerland
    Pediatr Transplant 14:23-32. 2010
    ..It also examines novel markers to discriminate between infection and rejection. Comments to each manuscript have been added, but we strongly encourage the reader to refer to the original work for more in depth evaluation...
  20. doi request reprint Memory B cell compartment constitution and susceptibility to recurrent lower respiratory tract infections in young children
    Johan N Siebert
    Department of Pediatrics, University Hospitals of Geneva and Medical School, University of Geneva, Geneva, Switzerland
    J Leukoc Biol 93:951-62. 2013
    ..However, the waning of antibodies might predispose children to recurrent infections in the absence of revaccination...
  21. doi request reprint Immune reconstitution inflammatory syndrome and solid organ transplant recipients: are children protected?
    Valerie A McLin
    Department of Pediatrics, Children s Hospital of Geneva, University Hospitals of Geneva, Geneva, Switzerland
    Pediatr Transplant 14:19-22. 2010
    ..However, IRIS has to date not been reported in pediatric SOT recipients. Here we review what is known and speculated about the pathogenesis of IRIS and propose that children may be relatively protected from IRIS...
  22. doi request reprint Tetanus immunity as a surrogate for past diphtheria-tetanus-pertussis immunization in migrant children
    Isabel Garcia de la Fuente
    Division of General Pediatrics, Department of Pediatrics, University Hospitals of Geneva and University of Geneva Medical School, Geneva, Switzerland
    Pediatr Infect Dis J 32:274-7. 2013
    ..Overimmunizing" is costly and associated with risks of hyperimmunization, whereas assuming up-to-date immunizations may be misleading...
  23. doi request reprint Severe autoimmune hemolytic anemia in a liver transplanted child
    Michela G Schäppi
    Division of Paediatric Gastroenterology and Transplantation, Children s Hospital of Geneva, Geneva, Switzerland
    Pediatr Transplant 12:809-12. 2008
    ..In this report, the etiologies of HA occurring in post-transplant pediatric patients are reviewed and the different treatment strategies are discussed...
  24. ncbi request reprint Frequent failure of adolescent booster responses to tetanus toxoid despite infant immunization: waning of infancy-induced immune memory?
    Klara M Posfay-Barbe
    Department of Pediatrics, University Hospitals of Geneva, Switzerland
    Vaccine 28:4356-61. 2010
    ..Thus, early life immune immaturity may limit the persistence of infant-induced immunity and subsequent boosters may be required for sustained protection...
  25. doi request reprint ABCB1 polymorphisms and neuropsychiatric adverse events in oseltamivir-treated children during influenza H1N1/09 pandemia
    Arnaud G L'huillier
    Geneva Medical Faculty and University Hospitals of Geneva, Department of Pediatrics, Geneva, Switzerland
    Pharmacogenomics 12:1493-501. 2011
    ..To examine the safety profile of oseltamivir in children and evaluate the impact of P-glycoprotein polymorphisms on the incidence of neuropsychiatric adverse events (NPAE) in oseltamivir-treated children...
  26. doi request reprint Protective antibody responses to influenza A/H1N1/09 vaccination in children with celiac disease
    Michela G Schäppi
    Department of Pediatrics, University Hospitals of Geneva, Geneva, Switzerland
    J Pediatr Gastroenterol Nutr 54:817-9. 2012
    ..All of the children with celiac disease reached protective antibody titers (≥40) and showed a geometric mean titer comparable with the control group (530 vs 573)...
  27. doi request reprint Individualized catheter surveillance among neonates: a prospective, 8-year, single-center experience
    Walter Zingg
    University of Geneva Hospitals and Faculty of Medicine, Geneva, Switzerland
    Infect Control Hosp Epidemiol 32:42-9. 2011
    ..To monitor trends in central line-associated bloodstream infections and clinical sepsis (CLABICS) among neonates and to determine risk factors for infection, especially dwell time...
  28. doi request reprint Electrogastrography abnormalities appear early in children with diabetes type 1
    Klara M Posfay-Barbe
    Department of Paediatrics, University Hospital of Geneva, Switzerland
    Eur J Gastroenterol Hepatol 23:881-5. 2011
    ....
  29. pmc Validation of SYBR Green based quantification assay for the detection of human Torque Teno virus titers from plasma
    Anuj Kumar Tyagi
    Department of Pediatrics, Onco Hematology Unit, Geneva University Hospital, Rue Willy Donze 6, 1211 Geneva, Switzerland
    Virol J 10:191. 2013
    ..We hereby describe the validation of a SYBR Green-based TTV quantification method for plasma samples...
  30. ncbi request reprint Increased incidence of apparently life-threatening events due to supine position
    Albane B R Maggio
    Department of Paediatrics, HCUG, Faculty of Medicine, Geneva, Switzerland
    Paediatr Perinat Epidemiol 20:491-6; discussion 496-7. 2006
    ..The worldwide marked decrease in SIDS since the implementation of the supine position possibly masks the negative effect of an increase in ALTE...
  31. doi request reprint Acute disseminated fatal toxoplasmosis after haploidentical stem cell transplantation despite atovaquone prophylaxis in a young man
    Isabel Garcia de la Fuente
    Department of Pediatrics, Division of General Pediatrics, University Hospitals of Geneva, Geneva, Switzerland
    Pediatr Infect Dis J 29:1059-60. 2010
    ..This report illustrates the need for protozoal monitoring despite atovaquone prophylaxis, in severely immunocompromised patients with intolerance to standard treatment...
  32. ncbi request reprint Pediatric chagas disease in europe: 45 cases from Spain and Switzerland
    Luciana Rodriguez-Guerineau
    From the Department of Pediatrics, University Hospitals of Geneva and University of Geneva, Switzerland Department of Pediatrics Laboratory of Microbiology, Sant Joan de Déu Hospital, University of Barcelona, Spain Department of Gynecology and Obstetrics Division of International and Humanitarian Medicine, Department of Community Medicine, Primary Care and Emergency Medicine and Division of Primary Care, Department of Community Medicine, Primary Care and Emergency Medicine, University Hospitals of Geneva and University of Geneva, Geneva, Switzerland
    Pediatr Infect Dis J 33:458-62. 2014
    ..To date, there is no published information about clinical characteristics in children...
  33. ncbi request reprint Antibiotic use in children - off-label use
    Walter Zingg
    Infection Control Program, University of Geneva Hospitals, 4 rue Gabrielle Perret Gentil, 1211 Geneva 14, Switzerland
    Curr Drug Targets 13:885-92. 2012
    ..This is of concern in the light of emerging multidrug-resistant pathogens...
  34. doi request reprint Human herpes virus type 8 seroprevalence in pregnant women in Geneva, Switzerland
    B Martinez de Tejada
    Department of Obstetrics and Gynecology, Faculty of Medicine, University Hospitals of Geneva, Geneva, Switzerland
    J Matern Fetal Neonatal Med 24:183-5. 2011
    ..43%; p = 0.023, respectively. In conclusion, HHV-8 infection is present in European pregnant women. Attention should be given to the emergence of infectious diseases, such as HHV-8, and their impact on health in nonendemic countries...
  35. ncbi request reprint Infection control in paediatrics
    Klara M Posfay-Barbe
    Children s Hospital of Geneva, University of Geneva Hospitals, Geneva, Switzerland
    Lancet Infect Dis 8:19-31. 2008
    ..We review the emergence of antimicrobial-resistant organisms and strategies to prevent health-care-associated infections in the paediatric setting...