Daniel D Pinschewer
Affiliation: University Hospital
Baumann C, Bonilla W, FrÃ¶hlich A, Helmstetter C, Peine M, Hegazy A, et al
. T-bet- and STAT4-dependent IL-33 receptor expression directly promotes antiviral Th1 cell responses. Proc Natl Acad Sci U S A. 2015;112:4056-61 pubmed publisher
..Thus, IL-33 acts as a critical and direct cofactor to drive antiviral Th1 effector cell activation, with implications for vaccination strategies and immunotherapeutic approaches. ..
Johnson S, Bergthaler A, Graw F, Flatz L, Bonilla W, Siegrist C, et al
. Protective efficacy of individual CD8+ T cell specificities in chronic viral infection. J Immunol. 2015;194:1755-62 pubmed publisher
..It demonstrates remarkable perseverance of all antiviral CTL specificities studied, thus raising hope for therapeutic vaccination in the treatment of persistent viral diseases. ..
Darbre S, Johnson S, Kallert S, Lambert P, Siegrist C, Pinschewer D. The Nucleoprotein Is Required for Lymphocytic Choriomeningitis Virus-Based Vaccine Vector Immunogenicity. J Virol. 2015;89:11734-8 pubmed publisher
..Hence, NP-dependent intracellular gene expression is essential for LCMV vector immunogenicity. ..