Arnaud Perrier

Summary

Affiliation: University of Geneva
Country: Switzerland

Publications

  1. ncbi request reprint Ten years after
    A Perrier
    Department of Internal Medicine, Division of General Internal Medicine, Geneva University Hospital and Geneva Faculty of Medicine, Geneva, Switzerland
    J Thromb Haemost 4:732-3. 2006
  2. pmc Physicians' views on resource availability and equity in four European health care systems
    Samia A Hurst
    Institute for Biomedical Ethics, Geneva University Medical School, Switzerland
    BMC Health Serv Res 7:137. 2007
  3. ncbi request reprint D-dimer testing and venous thromboembolism: four view points
    A Perrier
    Service of General Internal Medicine, Department of Internal Medicine, Geneva University Hospital and Geneva Faculty of Medicine, Geneva, Switzerland
    J Thromb Haemost 3:382-4. 2005
  4. ncbi request reprint [Randomised controlled trials: a reading guide]
    A Perrier
    Clinique de Médecine 1, Departement de Medecine, Hopital Cantonal Universitaire de Geneve, Geneve, Suisse, France
    Rev Mal Respir 19:505-14. 2002
  5. ncbi request reprint Cost-effectiveness analysis of diagnostic strategies for suspected pulmonary embolism including helical computed tomography
    Arnaud Perrier
    Medical Clinic 1, Geneva University Hospital, Geneva, Switzerland
    Am J Respir Crit Care Med 167:39-44. 2003
  6. ncbi request reprint [Towards a single society for specialists in family medicine and specialists in general internal medicine in Switzerland?]
    Arnaud Perrier
    Service de médecine interne générale, Departement de Medecine Interne, HUG, Geneve
    Rev Med Suisse 4:262-4, 266-8, 270-2. 2008
  7. ncbi request reprint [Clinical prediction rules: a reader's guide]
    A Perrier
    Clinique de Médecine 1, Departement de Medecine, Hopitaux Universitaires de Geneve, Suisse
    Rev Mal Respir 20:249-56. 2003
  8. ncbi request reprint [Clinical prediction rules: a readers' guide]
    A Perrier
    Clinique de Médecine 1, Departement de Medecine, Hôpitaux Universitaires de Genève AP, Institut de Medecine Sociale et Preventive, Faculté de Médecine de Genève Unité Qualité des Soins, Suisse
    Rev Mal Respir 21:S40-6. 2004
  9. ncbi request reprint Validation of helical computed tomography for suspected pulmonary embolism: a near miss?
    A Perrier
    Division of General Internal Medicine, Department of Internal Medicine, Geneva Faculty of Medicine and Geneva University Hospital, Geneva, Switerland
    J Thromb Haemost 3:14-6. 2005
  10. ncbi request reprint [Randomised controlled trials: a readers' guide]
    A Perrier
    Clinique de Médecine 1, Departement de Medecine, Hopital Cantonal Universitaire de Geneve, Geneve, Suisse
    Rev Mal Respir 21:S11-20. 2004

Detail Information

Publications122 found, 100 shown here

  1. ncbi request reprint Ten years after
    A Perrier
    Department of Internal Medicine, Division of General Internal Medicine, Geneva University Hospital and Geneva Faculty of Medicine, Geneva, Switzerland
    J Thromb Haemost 4:732-3. 2006
  2. pmc Physicians' views on resource availability and equity in four European health care systems
    Samia A Hurst
    Institute for Biomedical Ethics, Geneva University Medical School, Switzerland
    BMC Health Serv Res 7:137. 2007
    ..The perception of physicians, who witness the effects of these strategies, may provide useful insights regarding the impact of system-wide priority setting on access to care...
  3. ncbi request reprint D-dimer testing and venous thromboembolism: four view points
    A Perrier
    Service of General Internal Medicine, Department of Internal Medicine, Geneva University Hospital and Geneva Faculty of Medicine, Geneva, Switzerland
    J Thromb Haemost 3:382-4. 2005
  4. ncbi request reprint [Randomised controlled trials: a reading guide]
    A Perrier
    Clinique de Médecine 1, Departement de Medecine, Hopital Cantonal Universitaire de Geneve, Geneve, Suisse, France
    Rev Mal Respir 19:505-14. 2002
    ..Finally, a few limitations of randomised controlled trials are discussed...
  5. ncbi request reprint Cost-effectiveness analysis of diagnostic strategies for suspected pulmonary embolism including helical computed tomography
    Arnaud Perrier
    Medical Clinic 1, Geneva University Hospital, Geneva, Switzerland
    Am J Respir Crit Care Med 167:39-44. 2003
    ..In summary, including helical CT in diagnostic strategies for pulmonary embolism is cost-effective provided that it is combined with DD and US. In contrast, helical CT as a single test is not cost-effective...
  6. ncbi request reprint [Towards a single society for specialists in family medicine and specialists in general internal medicine in Switzerland?]
    Arnaud Perrier
    Service de médecine interne générale, Departement de Medecine Interne, HUG, Geneve
    Rev Med Suisse 4:262-4, 266-8, 270-2. 2008
    ..Moreover, they propose a training track individualized according to the trainee's future practice environment (hospital-based, urban or suburban outpatient practice)...
  7. ncbi request reprint [Clinical prediction rules: a reader's guide]
    A Perrier
    Clinique de Médecine 1, Departement de Medecine, Hopitaux Universitaires de Geneve, Suisse
    Rev Mal Respir 20:249-56. 2003
    ..Clinical prediction rules or scores are instruments that allow to quantify the respective contributions of medical history, clinical examination and laboratory tests to a diagnosis or a prognosis in a given patient...
  8. ncbi request reprint [Clinical prediction rules: a readers' guide]
    A Perrier
    Clinique de Médecine 1, Departement de Medecine, Hôpitaux Universitaires de Genève AP, Institut de Medecine Sociale et Preventive, Faculté de Médecine de Genève Unité Qualité des Soins, Suisse
    Rev Mal Respir 21:S40-6. 2004
  9. ncbi request reprint Validation of helical computed tomography for suspected pulmonary embolism: a near miss?
    A Perrier
    Division of General Internal Medicine, Department of Internal Medicine, Geneva Faculty of Medicine and Geneva University Hospital, Geneva, Switerland
    J Thromb Haemost 3:14-6. 2005
  10. ncbi request reprint [Randomised controlled trials: a readers' guide]
    A Perrier
    Clinique de Médecine 1, Departement de Medecine, Hopital Cantonal Universitaire de Geneve, Geneve, Suisse
    Rev Mal Respir 21:S11-20. 2004
  11. ncbi request reprint Multidetector-row computed tomography in suspected pulmonary embolism
    Arnaud Perrier
    Service of General Internal Medicine, Geneva Faculty of Medicine and Geneva University Hospital, Geneva, Switzerland
    N Engl J Med 352:1760-8. 2005
    ..We evaluated whether the use of D-dimer measurement and multidetector-row CT, without lower-limb ultrasonography, might safely rule out pulmonary embolism...
  12. ncbi request reprint [Fundamentals for interpreting diagnostic tests]
    A Perrier
    Service de médecine interne générale, Hopital Cantonal Universitaire de Geneve
    Praxis (Bern 1994) 94:555-61. 2005
  13. ncbi request reprint [Nurse-physician collaboration: a determinant of the quality of care?]
    Arnaud Perrier
    Service de médecine interne générale HUG, 1211 Geneve 14
    Rev Med Suisse 1:2742-5. 2005
    ..What is meant by collaboration should be better defined to allow developing strategies for training health care professionals to collaborate efficiently and for evaluating their impact on health care quality...
  14. ncbi request reprint Using clinical evaluation and lung scan to rule out suspected pulmonary embolism: Is it a valid option in patients with normal results of lower-limb venous compression ultrasonography?
    A Perrier
    Medical Clinic 1, Geneva University Hospital, Switzerland
    Arch Intern Med 160:512-6. 2000
    ..In patients with a low clinical probability of pulmonary embolism (PE) and a nondiagnostic lung scan, the prevalence of PE is theoretically very low. We assessed the safety and usefulness of this association for ruling out PE...
  15. ncbi request reprint Cost-effective diagnosis of deep vein thrombosis and pulmonary embolism
    A Perrier
    Medical Clinic 1, Department of Internal Medicine, Geneva University Hospital, Switzerland
    Thromb Haemost 86:475-87. 2001
    ..This paper reviews the performance of clinical evaluation and diagnostic tests for venous thromboembolism, and recently validated diagnostic schemes...
  16. ncbi request reprint Non-invasive diagnosis of venous thromboembolism in outpatients
    A Perrier
    Medical Clinic 1, Geneva University Hospital, Switzerland
    Lancet 353:190-5. 1999
    ....
  17. ncbi request reprint Evidence-based medicine and critical care
    A Perrier
    Department of Medicine, Geneva University Hospital
    Schweiz Med Wochenschr 129:1572-82. 1999
    ..Finally, the limitations of evidence-based medicine and its main instruments, i.e. randomised controlled trials and meta-analyses, are briefly discussed...
  18. ncbi request reprint Performance of helical computed tomography in unselected outpatients with suspected pulmonary embolism
    A Perrier
    Medical Clinic 1, Department of Internal Medicine, Geneva University Hospital, Rue Micheli du Crest 24, CH 1211 Geneva 14, Switzerland
    Ann Intern Med 135:88-97. 2001
    ..Helical computed tomography (CT) is commonly used to diagnose pulmonary embolism, although its operating characteristics have been insufficiently evaluated...
  19. ncbi request reprint [Diagnostic strategies for pulmonary embolism and decision analysis]
    A Perrier
    Clinique de Médecine 1, Hopital Cantonal, Hopitaux Universitaires de Geneve
    Rev Mal Respir 16:927-38. 1999
    ..However, such a conclusion awaits the validation of algorithms including CTscan by clinical outcome trials, in which the therapeutic decision would rest on the result of the spiral CTscan...
  20. ncbi request reprint A prediction rule to identify low-risk patients with pulmonary embolism
    Drahomir Aujesky
    Division of General Internal Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA
    Arch Intern Med 166:169-75. 2006
    ..A simple prognostic model could help identify patients with pulmonary embolism who are at low risk of death and are candidates for outpatient treatment...
  21. ncbi request reprint Diagnosing pulmonary embolism in outpatients with clinical assessment, D-dimer measurement, venous ultrasound, and helical computed tomography: a multicenter management study
    Arnaud Perrier
    Medical Clinic 1, Geneva University Hospital, Switzerland
    Am J Med 116:291-9. 2004
    ..To evaluate a diagnostic strategy for pulmonary embolism that combined clinical assessment, plasma D-dimer measurement, lower limb venous ultrasonography, and helical computed tomography (CT)...
  22. pmc Derivation and validation of a prognostic model for pulmonary embolism
    Drahomir Aujesky
    Division of General Internal Medicine, Clinical Epidemiology Center, University of Lausanne, Lausanne, Switzerland
    Am J Respir Crit Care Med 172:1041-6. 2005
    ..An objective and simple prognostic model for patients with pulmonary embolism could be helpful in guiding initial intensity of treatment...
  23. ncbi request reprint The challenge of diagnosing pulmonary embolism in elderly patients: influence of age on commonly used diagnostic tests and strategies
    Marc Righini
    Division of Angiology and Hemostasis, Geneva University Hospital and Faculty of Medicine, Geneva, Switzerland
    J Am Geriatr Soc 53:1039-45. 2005
    ..Therefore, a rational diagnostic approach to PE in older people should rest mainly on the sequential use of those tests that have demonstrated strong diagnostic yield, accuracy, and safety in this population...
  24. ncbi request reprint Comparison of four strategies for diagnosing deep vein thrombosis: a cost-effectiveness analysis
    N Perone
    Medical Clinic 2 (NP, Department of Medicine, Geneva University Hospital, Geneva, Switzerland
    Am J Med 110:33-40. 2001
    ..Serial ultrasonography is less cost-effective...
  25. ncbi request reprint Clinical usefulness of D-dimer testing in cancer patients with suspected pulmonary embolism
    Marc Righini
    Division of Angiology and Hemostasis, Department of Internal Medicine, Geneva University Hospital and Faculty of Medicine, 24 Rue Micheli du Crest, CH 1211 Geneva 14, Switzerland
    Thromb Haemost 95:715-9. 2006
    ..Increasing the cut-off value of D-dimer in cancer patients might increase the test's clinical usefulness...
  26. pmc Brief report: beyond clinical experience: features of data collection and interpretation that contribute to diagnostic accuracy
    Mathieu R Nendaz
    Unit of Development and Research in Medical Education, University of Geneva, Faculty of Medicine and Geneva University Hospitals, Geneva, Switzerland
    J Gen Intern Med 21:1302-5. 2006
    ..OBJECTIVE, DESIGN: Prospective, observational study, to determine the respective contribution of clinical experience and data collection features to diagnostic accuracy...
  27. ncbi request reprint Exclusion of pulmonary embolism using C-reactive protein and D-dimer. A prospective comparison
    Drahomir Aujesky
    Department of Medicine, University Hospital of Lausanne, Switzerland
    Thromb Haemost 90:1198-203. 2003
    ..Standard CRP tests alone or combined with clinical probability assessment cannot safely exclude PE...
  28. doi request reprint Diagnosis of pulmonary embolism by multidetector CT alone or combined with venous ultrasonography of the leg: a randomised non-inferiority trial
    Marc Righini
    Division of Angiology and Hemostasis, Geneva University Hospital and Faculty of Medicine, Geneva, Switzerland
    Lancet 371:1343-52. 2008
    ..We compared this combination with a strategy in which both a negative venous ultrasonography of the leg and MSCT were needed to exclude pulmonary embolism...
  29. ncbi request reprint Usefulness of preemptive anticoagulation in patients with suspected pulmonary embolism: a decision analysis
    Marc Blondon
    Division of General Internal Medicine, Department of Internal Medicine, University Hospitals of Geneva, Geneva, Switzerland
    Chest 142:697-703. 2012
    ..The objective of this study was to compare the risks and benefits of bid low-molecular-weight heparin vs no treatment in patients with suspected PE...
  30. ncbi request reprint Common strategies in clinical data collection displayed by experienced clinician-teachers in internal medicine
    Mathieu R Nendaz
    University of Geneva Faculty of Medicine, Department of Internal Medicine and UDREM, Geneva, Switzerland
    Med Teach 27:415-21. 2005
    ..Whether making teachers explicitly conscious about their own reasoning processes may help them better model and explain their diagnostic approach to specific cases should be assessed in follow-up studies...
  31. doi request reprint Diagnosis of venous thromboembolism: an update
    Henri Bounameaux
    Division of Angiology and Hemostasis, Department of Internal Medicine, University Hospitals of Geneva and Faculty of Medicine, Geneva, Switzerland
    Vasc Med 15:399-406. 2010
    ..This review gives a critical appraisal of the sequential steps of the diagnostic work-up in suspected DVT or PE...
  32. ncbi request reprint Validation of a risk score identifying patients with acute pulmonary embolism, who are at low risk of clinical adverse outcome
    Mathieu R Nendaz
    Medical Clinic 1, Department of Internal Medicine, Geneva University Hospitals, Switzerland
    Thromb Haemost 91:1232-6. 2004
    ..Whether this score remains accurate and useful in clinical practice should be determined in a prospective multicentre validation study...
  33. doi request reprint Thromboprophylaxis with low-molecular-weight heparin after cesarean delivery
    Marc Blondon
    General Internal Medicine, Department of Internal Medicine, Geneva University Hospital and Faculty of Medicine, 24 Rue Micheli du Crest, CH 1211 Geneva 14, Switzerland
    Thromb Haemost 103:129-37. 2010
    ..Our decision analysis suggests that the benefits of LMWH after cesarean delivery exceed the risks. This benefit is, however, very low in women with no risk factors...
  34. ncbi request reprint Diagnostic strategies for suspected pulmonary embolism among outpatients
    H Bounameaux
    Division of Angiology and Hemostasis, University Hospital of Geneva, Geneva, Switzerland
    Semin Vasc Med 1:189-94. 2001
    ..The results indicate that they should now be implemented in daily practice taking into account local facilities and expertise. The exact place of helical computed tomography in such sequential algorithms remains to be established...
  35. ncbi request reprint Clinical usefulness of D-dimer depending on clinical probability and cutoff value in outpatients with suspected pulmonary embolism
    Marc Righini
    Division of Angiology and Hemostasis, Geneva University Hospital, 24, Rue Micheli du Crest, 1211 Geneva 14, Switzerland
    Arch Intern Med 164:2483-7. 2004
    ....
  36. doi request reprint Prognostic value of the Geneva prediction rule in patients with pulmonary embolism
    Laurent Bertoletti
    Division of Angiology and Haemostasis, Department of Internal Medicine, Geneva Faculty of Medicine, University of Geneva, CH 1211 Geneva, Switzerland
    Thromb Res 132:32-6. 2013
    ..Some items of the Geneva prediction rule may have a prognostic value. We analyzed whether the initial probability assessed by the Geneva rule was associated with the outcome of patients with PE...
  37. ncbi request reprint Live or computerized simulation of clinical encounters: do clinicians work up patient cases differently?
    Mathieu R Nendaz
    Clinique de Médecine 1, University Hospitals, Geneva, Switzerland
    Med Inform Internet Med 31:1-8. 2006
    ..Its contribution to extend the competence of learners in clinical settings should be further evaluated...
  38. ncbi request reprint Clinical relevance of distal deep vein thrombosis. Review of literature data
    Marc Righini
    Division of Angiology and Hemostasis, Geneva University Hospital, 24, Rue Micheli du Crest, 1211 Geneva 14, Switzerland
    Thromb Haemost 95:56-64. 2006
    ..There is an urgent need for randomised trials assessing the usefulness of anticoagulant treatment in distal DVT...
  39. ncbi request reprint [The COPD-PE study: prevalence and prediction of pulmonary embolism in acute exacerbations of chronic obstructive pulmonary disease]
    A Perrier
    Departement de Medecine Interne, Hopitaux Universitaires de Geneve, Geneve, Suisse
    Rev Mal Respir 21:791-6. 2004
    ..To attempt to develop a prediction guide for PE in this population in order to identify the patients in whom PE should be investigated...
  40. ncbi request reprint Pulmonary embolism: from clinical presentation to clinical probability assessment
    A Perrier
    Medical Clinics 1 and 2, Department of Internal Medicine, Geneva University Hospital, Geneva, Switzerland
    Semin Vasc Med 1:147-54. 2001
    ..Finally, clinical assessment contributes significantly to the cost savings associated with modern noninvasive strategies...
  41. ncbi request reprint Influence of specific alternative diagnoses on the probability of pulmonary embolism
    Ariane Testuz
    Division of Angiology and Hemostasis, Geneva University Hospital and Faculty of Medicine, Geneva, Switzerland
    Thromb Haemost 95:958-62. 2006
    ....
  42. doi request reprint Acquisition of clinical competence: Added value of clerkship real-life contextual experience
    Andrea Rudaz
    Department of General Internal Medicine, Unit of Development and Research in Medical Education, Faculty of Medicine, Geneva University Hospital, University of Geneva, Geneva, Switzerland
    Med Teach 35:e957-62. 2013
    ..Medical students' limited access to patients induces a shift of learning activities from clinical wards to classrooms...
  43. ncbi request reprint A new rapid point-of-care D-dimer enzyme-linked immunosorbent assay (Stratus CS D-dimer) for the exclusion of venous thromboembolism
    Guido Reber
    Division of Angiology and Haemostasis, Geneva University Hospital, Switzerland
    Blood Coagul Fibrinolysis 15:435-8. 2004
    ..At 400 ng/ml, three results were false-negative, one with both devices and two with the Stratus D-dimer only. Stratus D-dimer appears to be suitable for the exclusion of venous thromboembolism in the emergency room setting...
  44. ncbi request reprint Physicians' access to ethics support services in four European countries
    Samia A Hurst
    Institute for Biomedical Ethics, Medical Faculty, University of Geneva, Geneva, Switzerland
    Health Care Anal 15:321-35. 2007
    ..Such support services may also need to be more proactive in making their help available...
  45. ncbi request reprint [Update in hospital internal medicine (2007): a selection]
    Mathieu Nendaz
    Service de médecine interne générale, Departement de Medecine Interne, HUG, Geneve
    Rev Med Suisse 4:279-82, 284-8. 2008
    ..Some data stimulating our reflection on the integration of medical education in health care centres and on the validity of some scientific publications are also presented...
  46. ncbi request reprint Effect of teaching context and tutor workshop on tutorial skills
    Anne Baroffio
    Unit of Development and Research in Medical Education, University of Geneva, School of Medicine, Geneve, Switzerland
    Med Teach 28:e112-9. 2006
    ..Thus, to be efficient, the design of a workshop should consider not only individual tutors' needs, but also the background of their teaching units, with special attention to their internal organization and tutor group functioning...
  47. ncbi request reprint [Hospital based internal medicine: a year in review]
    Sebastian Carballo
    Service de médecine interne générale, Departement de Medecine Interne, HUG, 1211 Geneve 14
    Rev Med Suisse 7:289-92, 294-5. 2011
    ..This selective review describes some recent studies that provide insight in various areas such as cardiovascular disease, heart failure, renovascular disease, venous thromboembolic disease, pneumonia, as well as acute pancreatitis...
  48. ncbi request reprint [Pulmonary embolism: role of the diagnostic and prognostic scores]
    Henri Bounameaux
    Departement de Medecine Interne, HUG, Geneve
    Rev Med Suisse 6:282, 284-6. 2010
    ..Prognostic scores have also been developed in order to stratify patients for the different therapeutic options: outpatient or inpatient treatment, anticoagulant treatment or thrombolysis or surgical or endovascular mechanical treatment...
  49. doi request reprint Differences in clinical presentation of pulmonary embolism in women and men
    H Robert-Ebadi
    Division of Angiology and Hemostasis, Geneva University Hospital and Faculty of Medicine, Geneva, Switzerland
    J Thromb Haemost 8:693-8. 2010
    ..The risk of recurrence of pulmonary embolism (PE) is higher in men than in women. Differences in clinical presentation of deep vein thrombosis (DVT) have been reported between the two genders but comparative data on PE are lacking...
  50. ncbi request reprint Correlation between cardiac biomarkers and right ventricular enlargement on chest CT in non massive pulmonary embolism
    Nicolas Vuilleumier
    Department of Pathology, Clinical Chemistry, Geneva University Hospital, Switzerland
    Thromb Res 121:617-24. 2008
    ..Troponin I (cTnI), myoglobin, heart-type fatty acid binding protein (H-FABP), and natriuretic peptides (BNP, NTproBNP) were all reported to be elevated in patients with pulmonary embolism (PE)...
  51. ncbi request reprint Diagnosis of pulmonary embolism: in transition
    Henri Bounameaux
    Division of Angiology and Hemostasis, Department of Internal Medicine, University Hospital of Geneva, CH 1211 Geneva 14, Switzerland
    Curr Opin Hematol 13:344-50. 2006
    ..To discuss reports published in 2005 on the diagnosis of clinically suspected nonmassive pulmonary embolism...
  52. ncbi request reprint Comparison of two clinical prediction rules and implicit assessment among patients with suspected pulmonary embolism
    Isabelle Chagnon
    Division of Angiology and Hemostasis, Geneva University Hospital, Geneva, Switzerland
    Am J Med 113:269-75. 2002
    ..We compared the predictive accuracy and the concordance of the two methods, as well as the Geneva score overridden by implicit clinical judgment...
  53. pmc Should pulmonary embolism be suspected in exacerbation of chronic obstructive pulmonary disease?
    Olivier T Rutschmann
    Division of General Internal Medicine, Department of Medicine, Geneva University Hospitals, 24 Rue Micheli du Crest, 1211 Geneva 14, Switzerland
    Thorax 62:121-5. 2007
    ..The cause of acute exacerbation of chronic obstructive pulmonary disease (COPD) is often difficult to determine. Pulmonary embolism may be a trigger of acute dyspnoea in patients with COPD...
  54. ncbi request reprint Evaluation of advanced D-dimer assay for the exclusion of venous thromboembolism
    Guido Reber
    Division of Angiology and Haemostasis, Geneva University Hospital, Geneva 14, Switzerland
    Thromb Res 107:197-200. 2002
    ..5% (88.9, 98.8) and 47.8% (40.8, 54.9) at a cutt-off value of 1.1 microg/ml. This assay appears promising and should be validated in clinical practise to assess its place in the work-up schemes of thromboembolism...
  55. doi request reprint Diagnostic errors and flaws in clinical reasoning: mechanisms and prevention in practice
    Mathieu Nendaz
    Service of General Internal Medicine, University Hospitals, Geneva, Switzerland
    Swiss Med Wkly 142:w13706. 2012
    ....
  56. doi request reprint Including patients in resuscitation decisions in Switzerland: from doing more to doing better
    Samia A Hurst
    Institute for Biomedical Ethics, Geneva University Medical School, Geneva, Switzerland
    J Med Ethics 39:158-65. 2013
    ..Decisions regarding Cardio-Pulmonary Resuscitation (CPR) and Do Not Attempt Resuscitation (DNAR) orders remain demanding, as does including patients in the process...
  57. ncbi request reprint Degree of concurrency among experts in data collection and diagnostic hypothesis generation during clinical encounters
    Mathieu R Nendaz
    University of Geneva Faculty of Medicine, Geneva, Switzerland
    Med Educ 38:25-31. 2004
    ..The use of data elicited by experts solving problems independently has been advocated as a method of setting performance standards...
  58. pmc Patient assessments of the most important medical decision during a hospitalization
    Thomas V Perneger
    Division of Clinical Epidemiology, University Hospitals of Geneva, Geneva, Switzerland
    J Gen Intern Med 23:1659-65. 2008
    ..How medical decisions are made in real-life situations is largely unexplored. We explored patients' perceptions of decision-making during a hospitalization and examined the conformity of the decision process with expert recommendations...
  59. ncbi request reprint Effect of age on the performance of single detector helical computed tomography in suspected pulmonary embolism
    Marc Righini
    Division of Angiology and Hemostasis, Geneva University Hospital, Geneva, Switzerland
    Thromb Haemost 91:296-9. 2004
    ..Our data suggest that age does not have a marked influence on the diagnostic performances of hCT in clinically suspected pulmonary embolism...
  60. ncbi request reprint Performances of the fibrin monomer test for the exclusion of pulmonary embolism in symptomatic outpatients
    G Reber
    Division of Angiology and haemostasis and Medical Clinic 1, Geneva University Hospital, Switzerland
    Thromb Haemost 81:221-3. 1999
    ..In conclusion, this is the first study suggesting the interest of this Fibrin Monomer test to rule out PE; these results, however, need to be confirmed by other studies...
  61. ncbi request reprint Diagnostic approaches to suspected deep vein thrombosis and pulmonary embolism
    Henri Bounameaux
    Division of Angiology and Hemostasis, Department of Internal Medicine, University Hospital of Geneva, Geneva, Switzerland
    Hematol J 4:97-103. 2003
    ....
  62. ncbi request reprint [What to do in case of disagreement between physician and patient: a few legal and ethical considerations]
    Sylvie Ray
    Service de médecine interne générale, HUG, 1211 Geneve 14
    Rev Med Suisse 4:2538-41. 2008
    ..Early discussion with a competent patient and establishment of advance directives is therefore extremely important...
  63. ncbi request reprint Tutor training, evaluation criteria and teaching environment influence students' ratings of tutor feedback in problem-based learning
    Anne Baroffio
    Faculty of Medicine, Unit of Development and Research in Medical Education, University of Geneva, 1 rue Michel Servet, CH 1211, Geneva 4, Switzerland
    Adv Health Sci Educ Theory Pract 12:427-39. 2007
    ....
  64. doi request reprint Complete venous ultrasound in outpatients with suspected pulmonary embolism
    M Righini
    Division of Angiology and Haemostasis, Department of Internal Medicine, Geneva University Hospital and Faculty of Medicine, Geneva, Switzerland
    J Thromb Haemost 7:406-12. 2009
    ..Recent studies suggested a limited yield of proximal US when multislice computed tomography (MSCT) was used...
  65. ncbi request reprint Performances of a new, automated latex assay for the exclusion of venous thromboembolism
    G Reber
    Division of Angiology and Haemostasis, Geneva University Hospital, Switzerland
    Blood Coagul Fibrinolysis 12:217-20. 2001
    ..6-99.4). This new assay is fast and fully automated, and its performance is suitable to exclude venous thromboembolism. Management studies should be performed to assess its utility...
  66. ncbi request reprint Assessing clinical probability of pulmonary embolism in the emergency ward: a simple score
    J Wicki
    Medical Clinic 1, Department of Internal Medicine, Geneva University Hospital, 24 rue Micheli-du-Crest, CH-1211 Geneva 14, Switzerland
    Arch Intern Med 161:92-7. 2001
    ..Applying this score to emergency ward patients suspected of having PE could allow a more effective diagnostic process...
  67. ncbi request reprint Influence of age on the cost-effectiveness of diagnostic strategies for suspected pulmonary embolism
    M Righini
    Division of Angiology and Haemostasis, Department of Internal Medicine, Geneva University Hospital and Faculty of Medicine, Geneva, Switzerland
    J Thromb Haemost 5:1869-77. 2007
    ....
  68. doi request reprint [D-dimers measurement to predict the risk of thromboembolic recurrence]
    M Righini
    Division d angiologie et d hémostase, Hopitaux Universitaires de Geneve, 24, Rue Micheli du Crest, 1211 Geneve, Suisse
    Rev Med Interne 29:476-81. 2008
    ..Recently, D-dimer measurement has been used to predict the risk of recurrence and to tailor anticoagulant therapy on an individual basis...
  69. doi request reprint Cardiac biomarkers for risk stratification in non-massive pulmonary embolism: a multicenter prospective study
    N Vuilleumier
    Division of Laboratory Medicine, Department of Genetics and Laboratory Medicine, Geneva University Hospitals and University of Geneva, Geneva, Switzerland
    J Thromb Haemost 7:391-8. 2009
    ..Troponins (cTnI and cTnT), N-terminal pro-Brain Natriuretic Peptide (NT-proBNP), myoglobin, heart-type fatty acid-binding protein (H-FABP) and fibrin D-Dimer are emergent candidates for risk stratification in pulmonary embolism (PE)...
  70. doi request reprint Venous thromboembolism: contemporary diagnostic and therapeutic aspects
    H Bounameaux
    Division of Angiology and Hemostasis, Department of Internal Medicine, University Hospitals of Geneva and Faculty of Medicine, Geneva, Switzerland
    Vasa 37:211-26. 2008
    ..5-2) after an initial full-intensity treatment (INR 2-3) period of 3 to 12 months, and the emergence of new anticoagulant drugs such as direct oral synthetic inhibitors of thrombin or factor Xa...
  71. ncbi request reprint [Analysis of a diagnostic test: ROC curve or "receiver operating characteristic"]
    T Perneger
    Service qualité des soins TP et Clinique médicale, Département de médecine interne AP, Hopitaux Universitaires de Geneve, Suisse
    Rev Mal Respir 21:398-401. 2004
  72. ncbi request reprint LMWH contra LMWH: superior, equivalent or non-inferior?
    H Bounameaux
    Division of Angiology and Hemostasis and Medical Clinic, Department of Internal Medicine, University Hospital of Geneva, Geneva, Switzerland
    J Thromb Haemost 1:414-5. 2003
  73. ncbi request reprint Cost-effectiveness of noninvasive diagnostic aids in suspected pulmonary embolism
    A Perrier
    Medical Clinic 1, Geneva University Hospital, Switzerland
    Arch Intern Med 157:2309-16. 1997
    ....
  74. ncbi request reprint [Contribution of laboratory tests and venous investigations in the diagnosis of pulmonary embolism]
    A Perrier
    , , , Suisse
    Arch Mal Coeur Vaiss 88:1699-707. 1995
    ..More extensive use of D-dimer in clinical practice requires more rapid and equally reliable unitary tests as the ELISA...
  75. pmc Sensitivity and predictive value of 15 PubMed search strategies to answer clinical questions rated against full systematic reviews
    Thomas Agoritsas
    Division of Clinical Epidemiology, University Hospitals of Geneva, Geneva, Switzerland
    J Med Internet Res 14:e85. 2012
    ..Little is known about the performance of search strategies when they are applied to answer specific clinical questions...
  76. ncbi request reprint Drug-induced long QT syndrome in injection drug users receiving methadone: high frequency in hospitalized patients and risk factors
    Georg B Ehret
    Division of Clinical Pharmacology and Toxicology, Geneva University Hospital, 24 Rue Micheli du Crest, CH 1211 Geneva 14, Switzerland
    Arch Intern Med 166:1280-7. 2006
    ..In the inpatient setting, the frequency of QT interval prolongation with methadone treatment, its dose dependence, and the importance of cofactors such as drug-drug interactions remain unknown...
  77. doi request reprint From dyspnea to pulmonary embolism
    Arnaud Perrier
    Division of General Internal Medicine, Geneva University Hospitals, Geneva
    Ther Umsch 66:643-7. 2009
    ..Patients with obvious alternative diagnoses such as acute left heart failure, pneumonia or acute coronary syndrome should not be investigated for PE...
  78. ncbi request reprint Validation of a clinical prognostic model to identify low-risk patients with pulmonary embolism
    D Aujesky
    Division of General Internal Medicine, University Outpatient Clinic, Clinical Epidemiology Center, University of Lausanne, Lausanne, Switzerland
    J Intern Med 261:597-604. 2007
    ..To validate the Pulmonary Embolism Severity Index (PESI), a clinical prognostic model which identifies low-risk patients with pulmonary embolism (PE)...
  79. ncbi request reprint Clinical and laboratory diagnosis of deep vein thrombosis: new cost-effective strategies
    H Bounameaux
    Division of Angiology and Hemostasis, Medical Clinic, University Hospital of Geneva, Geneva, Switzerland
    Semin Vasc Med 1:39-42. 2001
    ..The results indicate that they should now be implemented in daily practice, taking into account local facilities and expertise...
  80. ncbi request reprint Suspicion of pulmonary embolism in outpatients: nonspecific chest pain is the most frequent alternative diagnosis
    S Bernard Bagattini
    Division of Angiology and Hemostasis, Geneva University Hospital, Geneva, Switzerland
    J Intern Med 256:153-60. 2004
    ..Our aim was to evaluate whether clinical characteristics would allow predicting alternative diagnoses other than pulmonary embolism thereby ruling out venous thromboembolism...
  81. ncbi request reprint Nutritional assessment: lean body mass depletion at hospital admission is associated with an increased length of stay
    Claude Pichard
    Clinical Nutrition Department, Geneva University Hospital, Geneva, Switzerland
    Am J Clin Nutr 79:613-8. 2004
    ..Low fat-free mass may be an independent risk factor for malnutrition that results in an increased length of hospital stay (LOS)...
  82. ncbi request reprint Exploring the major difficulties perceived by residents in training: a pilot study
    Christophe Luthy
    Internal Medicine and Rehabilitation Clinic, Geneva University Hospital, 26 avenue de Beau Séjour, CH 1211 Geneva 14, Switzerland
    Swiss Med Wkly 134:612-7. 2004
    ..To assess residents' difficulties during the first year of residency. In contrast to previous studies that mainly used structured questionnaires, a qualitative procedure was applied...
  83. ncbi request reprint [Stable and asymptomatic coronary heart disease: a new paradign]
    Carole Baumgartner
    Service de médecine interne générale, Departement de Medecine Interne, HUG, 1211 Geneve 14
    Rev Med Suisse 6:1951-4, 1956. 2010
    ..Furthermore, initial revascularization in patients with stable coronary heart disease, and no high risk lesions or disabling angina, has no benefit over medical management of CVRF...
  84. pmc Prevalence and determinants of physician bedside rationing: data from Europe
    Samia A Hurst
    Bioethics Institute, University of Geneva Medical School, Geneva, Switzerland
    J Gen Intern Med 21:1138-43. 2006
    ..Bedside rationing by physicians is controversial. The debate, however, is clouded by lack of information regarding the extent and character of bedside rationing...
  85. ncbi request reprint [Iron-deficient anemia, anemia of chronic disease or mixed anemia: how to determine the diagnosis?]
    Julien Celi
    Service de médecine interne générale, Departement de Medecine Interne, réhabilitation et gériatrie, HUG, 1211 Geneve 14
    Rev Med Suisse 7:2018, 2020-3. 2011
    ..The objective of this article is to give an overview of the current diagnostic tools for the evaluation of the iron metabolism and to provide a practical diagnostic algorithm for the evaluation of iron-deficient anemia...
  86. ncbi request reprint [Hospital based internal medicine: the year 2009 in review (2)]
    Sebastian Carballo
    Service de médecine interne générale, Departement de Medecine Interne, HUG, 1211 Geneve 14
    Rev Med Suisse 6:228-32. 2010
    ..The presurgical evaluation of lung cancer, the level of glucose control to be achieved in the intensive care unit, and novel methods of teaching medicine are also discussed...
  87. ncbi request reprint [Study evaluating a diagnostic test: a readers' guide]
    M R Nendaz
    Departement de Medecine Interne, Hopitaux Universitaires de Geneve, Geneve, Suisse
    Rev Mal Respir 21:S26-36. 2004
  88. ncbi request reprint [Update in hospital medicine 2008]
    S Carballo
    Service de médecine interne générale, HUG, 1211 Geneve 14
    Rev Med Suisse 5:244-50. 2009
    ..Other topics include pneumonia prognosis, the management of ascitis fluid or of septic shock, and methodology...
  89. ncbi request reprint [Sensitivity, specificity, positive and negative predictive value of a diagnostic test]
    M R Nendaz
    Clinique de Médecine 1, Hopitaux Universitaires de Geneve, Suisse
    Rev Mal Respir 21:390-3. 2004
  90. ncbi request reprint [Anticoagulants and cancer: beyond thromboembolic disease prevention]
    F R Jornayvaz
    Service de médecine interne générale, Departement de Medecine Interne, HUG, 1211 Geneve 14
    Rev Med Suisse 2:2350-3. 2006
    ..This benefit seems to be related to an inhibitory effect on tumoral progression. LMWH seems promising in an eventual routine clinical use. However, their type, dose and duration and in which cancers has to be further defined...
  91. ncbi request reprint Prediction of pulmonary embolism extent by clinical findings, D-dimer level and deep vein thrombosis shown by ultrasound
    C Galle
    Division of Angiology and Hemostasis, Geneva University Hospital, Switzerland
    Thromb Haemost 86:1156-60. 2001
    ....
  92. ncbi request reprint [Bayes theorem and likelihood ratios]
    M R Nendaz
    Clinique de Médecine 1, Hopitaux Universitaires de Geneve, Suisse
    Rev Mal Respir 21:394-7. 2004
  93. ncbi request reprint Spectrum bias: a quantitative and graphical analysis of the variability of medical diagnostic test performance
    Catherine Goehring
    Clinical Epidemiology Division, University Hospital, Geneva, Switzerland
    Stat Med 23:125-35. 2004
    ..We conclude that spectrum effect is more common than spectrum bias and that clinical decisions are affected only under certain conditions...
  94. ncbi request reprint Medical researchers evaluate their methodological skills
    Thomas V Perneger
    Quality of Care Unit, Geneva University Hospitals, CH 1211 Geneva 14, Switzerland
    J Clin Epidemiol 57:1323-9. 2004
    ..Clinical epidemiology and statistics skills of clinical researchers are often limited. We assessed methodological skills of medical researchers and identified factors associated with higher skill levels...
  95. ncbi request reprint [D-dimer dosage for the prediction of recurrent venous thromboembolism]
    R Guanella
    Service de médecine interne générale, Departement de Medecine, HUG, Geneve
    Rev Med Suisse 3:2335-8. 2007
    ..Despite theses results, evidence of using D-dimer for tailoring duration of anticoagulation is still sparse...
  96. doi request reprint Clinical prediction rules for pulmonary embolism: a systematic review and meta-analysis
    E Ceriani
    Division of Angiology and Hemostasis, Geneva University Hospital and Faculty of Medicine, Geneva, Switzerland
    J Thromb Haemost 8:957-70. 2010
    ..Pretest probability assessment is necessary to identify patients in whom pulmonary embolism (PE) can be safely ruled out by a negative D-dimer without further investigations...
  97. doi request reprint D-Dimer for venous thromboembolism diagnosis: 20 years later
    M Righini
    Division of Angiology and Hemostasis, Department of Internal Medicine, Geneva University Hospital and Faculty of Medicine, Geneva, Switzerland
    J Thromb Haemost 6:1059-71. 2008
    ....
  98. ncbi request reprint [Validation study of a diagnostic test: a guide to critical appraisal. Report on the role of endobronchial biopsy in the diagnosis of sarcoidosis]
    M R Nendaz
    Departement de Medecine Interne, Hopitaux Universitaires de Geneve, Geneve, Suisse
    Rev Mal Respir 19:767-77. 2002
    ....
  99. ncbi request reprint [Proper usage of procalcitonin]
    Y Green
    Service de médecine interne générale, Departement de Medecine Interne, HUG, Geneve
    Rev Med Suisse 3:2330-2, 2334. 2007
    ..Results are encouraging but preliminary, therefore procalcitonine measurement should be restricted to patients with criteria of severe infection for the time being...
  100. ncbi request reprint [Analysis of variance, part 1 (the t-test and ANOVA)]
    T Perneger
    Service qualité des soins, Hopitaux Universitaires de Geneve, Geneve, Suisse
    Rev Mal Respir 21:797-801. 2004
  101. ncbi request reprint [Nesiritide in heart failure: commercial success or therapeutic advance?]
    T Stampfli
    Service de médecine interne générale, HUG, Geneve
    Rev Med Suisse 2:295-8. 2006
    ..In the absence of further large scale studies with relevant endpoints, which are now unlikely to be conducted, nesiritide is rapidly disappearing from the therapeutic armamentarium...