Genomes and Genes
Affiliation: University of Zurich
- Long-distance axonal regeneration induced by CNTF gene transfer is impaired by axonal misguidance in the injured adult optic nerveVincent Pernet
Brain Research Institute, University of Zurich, and Dept of Health Sciences and Technology, ETH Zurich, Winterthurerstrasse 190, CH 8057 Zurich, Switzerland
Neurobiol Dis 51:202-13. 2013....
- The role of Nogo-A in axonal plasticity, regrowth and repairVincent Pernet
Brain Research Institute, University of Zürich ETH, Department of Health Sciences and Technology ETH Zürich, Winterthurerstrasse 190, Room 55J34a, 8057 Zurich, Switzerland
Cell Tissue Res 349:97-104. 2012..Function-blocking anti-Nogo-A antibodies are currently being tested in a clinical trial for improved outcome after spinal cord injury...
- Nogo-A and myelin-associated glycoprotein differently regulate oligodendrocyte maturation and myelin formationVincent Pernet
Department of Biology, Brain Research Institute, University of Zurich, Swiss Federal Institute of Technology, CH 8057 Zurich, Switzerland
J Neurosci 28:7435-44. 2008..Together, our results demonstrate that Nogo-A and MAG are differently involved in oligodendrocyte maturation in vivo, and suggest that Nogo-A may influence also remyelination in pathological conditions such as multiple sclerosis...
- Pax6-positive Müller glia cells express cell cycle markers but do not proliferate after photoreceptor injury in the mouse retinaSandrine Joly
Laboratory for Retinal Cell Biology, Department of Ophthalmology, University of Zurich, Switzerland
Glia 59:1033-46. 2011..Our results suggest that a release of the S-phase blockade may be crucial for Müller cells to successfully transdifferentiate and replace injured photoreceptors in mammals...
- Synergistic action of brain-derived neurotrophic factor and lens injury promotes retinal ganglion cell survival, but leads to optic nerve dystrophy in vivoVincent Pernet
Department of Pathology and Cell Biology, , Montreal, Quebec, Canada
Brain 129:1014-26. 2006..We propose that loss of axonal integrity may limit neuronal recovery in the injured, adult CNS...
- Light-induced retinopathy: comparing adult and juvenile ratsSandrine Joly
Department of Biological Sciences, University of Montreal, and Department of Ophthalmology, McGill University-Montreal Children's Hospital Research Institute, Quebec, Canada
Invest Ophthalmol Vis Sci 47:3202-12. 2006..This window of resistance to light damage gradually weakens as the juvenile rat approaches its 1-month anniversary...
- Neuroprotection in the juvenile rat model of light-induced retinopathy: evidence suggesting a role for FGF-2 and CNTFSandrine Joly
Departments of Biological Sciences, University of Montreal, Quebec, Canada
Invest Ophthalmol Vis Sci 48:2311-20. 2007..The purpose of the present study was to investigate the cellular and molecular mechanisms underlying this endogenous resistance to light-induced damage...