Vincent Pernet

Summary

Affiliation: University of Zurich
Country: Switzerland

Publications

  1. ncbi request reprint Lost in the jungle: new hurdles for optic nerve axon regeneration
    Vincent Pernet
    Brain Research Institute, University of Zurich, and Department of Health Sciences and Technology, ETH Zurich, Winterthurerstrasse 190, CH 8057 Zurich, Switzerland Electronic address
    Trends Neurosci 37:381-7. 2014
  2. pmc Misguidance and modulation of axonal regeneration by Stat3 and Rho/ROCK signaling in the transparent optic nerve
    V Pernet
    Brain Research Institute, University of Zürich and Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland
    Cell Death Dis 4:e734. 2013
  3. doi request reprint Long-distance axonal regeneration induced by CNTF gene transfer is impaired by axonal misguidance in the injured adult optic nerve
    Vincent Pernet
    Brain Research Institute, University of Zurich, and Dept of Health Sciences and Technology, ETH Zurich, Winterthurerstrasse 190, CH 8057 Zurich, Switzerland
    Neurobiol Dis 51:202-13. 2013
  4. doi request reprint The role of Nogo-A in axonal plasticity, regrowth and repair
    Vincent Pernet
    Brain Research Institute, University of Zürich ETH, Department of Health Sciences and Technology ETH Zürich, Winterthurerstrasse 190, Room 55J34a, 8057 Zurich, Switzerland
    Cell Tissue Res 349:97-104. 2012
  5. doi request reprint Nogo-A and myelin-associated glycoprotein differently regulate oligodendrocyte maturation and myelin formation
    Vincent Pernet
    Department of Biology, Brain Research Institute, University of Zurich, Swiss Federal Institute of Technology, CH 8057 Zurich, Switzerland
    J Neurosci 28:7435-44. 2008
  6. ncbi request reprint New mouse retinal stroke model reveals direction-selective circuit damage linked to permanent optokinetic response loss
    Sandrine Joly
    Brain Research Institute, University of Zurich, and Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland
    Invest Ophthalmol Vis Sci 55:4476-89. 2014
  7. pmc Nogo-A is a negative regulator of CNS angiogenesis
    Thomas Wälchli
    Brain Research Institute, University of Zurich, CH 8057 Zurich, Switzerland
    Proc Natl Acad Sci U S A 110:E1943-52. 2013
  8. doi request reprint Pax6-positive Müller glia cells express cell cycle markers but do not proliferate after photoreceptor injury in the mouse retina
    Sandrine Joly
    Laboratory for Retinal Cell Biology, Department of Ophthalmology, University of Zurich, Switzerland
    Glia 59:1033-46. 2011
  9. pmc The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity
    Anissa Kempf
    Brain Research Institute, University of Zurich, and Dept of Health Sciences and Technology, Swiss Federal Institute of Technology, Zurich, Switzerland
    PLoS Biol 12:e1001763. 2014
  10. ncbi request reprint Neuroprotection in the juvenile rat model of light-induced retinopathy: evidence suggesting a role for FGF-2 and CNTF
    Sandrine Joly
    Departments of Biological Sciences, University of Montreal, Quebec, Canada
    Invest Ophthalmol Vis Sci 48:2311-20. 2007

Collaborators

Detail Information

Publications12

  1. ncbi request reprint Lost in the jungle: new hurdles for optic nerve axon regeneration
    Vincent Pernet
    Brain Research Institute, University of Zurich, and Department of Health Sciences and Technology, ETH Zurich, Winterthurerstrasse 190, CH 8057 Zurich, Switzerland Electronic address
    Trends Neurosci 37:381-7. 2014
    ..We propose that a balanced growth stimulatory treatment will have to be combined with guidance factors and suppression of local growth inhibitory factors to obtain the full regeneration of long CNS axonal tracts. ..
  2. pmc Misguidance and modulation of axonal regeneration by Stat3 and Rho/ROCK signaling in the transparent optic nerve
    V Pernet
    Brain Research Institute, University of Zürich and Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland
    Cell Death Dis 4:e734. 2013
    ..The correction of axonal misguidance was associated with improved long-distance axon regeneration in the injured adult CNS. ..
  3. doi request reprint Long-distance axonal regeneration induced by CNTF gene transfer is impaired by axonal misguidance in the injured adult optic nerve
    Vincent Pernet
    Brain Research Institute, University of Zurich, and Dept of Health Sciences and Technology, ETH Zurich, Winterthurerstrasse 190, CH 8057 Zurich, Switzerland
    Neurobiol Dis 51:202-13. 2013
    ....
  4. doi request reprint The role of Nogo-A in axonal plasticity, regrowth and repair
    Vincent Pernet
    Brain Research Institute, University of Zürich ETH, Department of Health Sciences and Technology ETH Zürich, Winterthurerstrasse 190, Room 55J34a, 8057 Zurich, Switzerland
    Cell Tissue Res 349:97-104. 2012
    ..Function-blocking anti-Nogo-A antibodies are currently being tested in a clinical trial for improved outcome after spinal cord injury...
  5. doi request reprint Nogo-A and myelin-associated glycoprotein differently regulate oligodendrocyte maturation and myelin formation
    Vincent Pernet
    Department of Biology, Brain Research Institute, University of Zurich, Swiss Federal Institute of Technology, CH 8057 Zurich, Switzerland
    J Neurosci 28:7435-44. 2008
    ..Together, our results demonstrate that Nogo-A and MAG are differently involved in oligodendrocyte maturation in vivo, and suggest that Nogo-A may influence also remyelination in pathological conditions such as multiple sclerosis...
  6. ncbi request reprint New mouse retinal stroke model reveals direction-selective circuit damage linked to permanent optokinetic response loss
    Sandrine Joly
    Brain Research Institute, University of Zurich, and Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland
    Invest Ophthalmol Vis Sci 55:4476-89. 2014
    ..Ischemic insults give rise to severe visual deficits after blood vessel occlusion. In this study we investigated the effects of retinal stroke on the direction-selective circuit of the inner retina in a new adult mouse model...
  7. pmc Nogo-A is a negative regulator of CNS angiogenesis
    Thomas Wälchli
    Brain Research Institute, University of Zurich, CH 8057 Zurich, Switzerland
    Proc Natl Acad Sci U S A 110:E1943-52. 2013
    ..These findings identify Nogo-A as an important negative regulator of developmental angiogenesis in the CNS. They may have important implications in CNS pathologies involving angiogenesis such as stroke, brain tumors, and retinopathies...
  8. doi request reprint Pax6-positive Müller glia cells express cell cycle markers but do not proliferate after photoreceptor injury in the mouse retina
    Sandrine Joly
    Laboratory for Retinal Cell Biology, Department of Ophthalmology, University of Zurich, Switzerland
    Glia 59:1033-46. 2011
    ..Our results suggest that a release of the S-phase blockade may be crucial for Müller cells to successfully transdifferentiate and replace injured photoreceptors in mammals...
  9. pmc The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity
    Anissa Kempf
    Brain Research Institute, University of Zurich, and Dept of Health Sciences and Technology, Swiss Federal Institute of Technology, Zurich, Switzerland
    PLoS Biol 12:e1001763. 2014
    ..Elucidating Nogo-A/S1PR2 signaling platforms will provide new insights into regulation of synaptic plasticity. ..
  10. ncbi request reprint Neuroprotection in the juvenile rat model of light-induced retinopathy: evidence suggesting a role for FGF-2 and CNTF
    Sandrine Joly
    Departments of Biological Sciences, University of Montreal, Quebec, Canada
    Invest Ophthalmol Vis Sci 48:2311-20. 2007
    ..The purpose of the present study was to investigate the cellular and molecular mechanisms underlying this endogenous resistance to light-induced damage...
  11. ncbi request reprint Light-induced retinopathy: comparing adult and juvenile rats
    Sandrine Joly
    Department of Biological Sciences, University of Montreal, and Department of Ophthalmology, McGill University Montreal Children s Hospital Research Institute, Quebec, Canada
    Invest Ophthalmol Vis Sci 47:3202-12. 2006
    ..To investigate the effect of chronic exposure to a bright, luminous environment, starting at the opening of the eyes, on the retinal structure and function of the suckling rat...
  12. ncbi request reprint Synergistic action of brain-derived neurotrophic factor and lens injury promotes retinal ganglion cell survival, but leads to optic nerve dystrophy in vivo
    Vincent Pernet
    Department of Pathology and Cell Biology, Universite de Montreal, Montreal, Quebec, Canada
    Brain 129:1014-26. 2006
    ..We propose that loss of axonal integrity may limit neuronal recovery in the injured, adult CNS...