Research Topics
Species | Michael D MuellerSummaryAffiliation: University Hospital Country: Switzerland Publications
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Publications
2,3,7,8-Tetrachlorodibenzo-p-dioxin increases glycodelin gene and protein expression in human endometriumMichael D Mueller
Endometriosis Center, Department of Obstetrics and Gynaecology, Inselspital, University of Bern, Effingerstrasse 102, 3010 Bern, Switzerland
J Clin Endocrinol Metab 90:4809-15. 2005..Glycodelin (GdA) is an immunosuppressive endometrial glycoprotein critical for embryonic implantation and pregnancy establishment...
Novel placental and nonplacental serum markers in ectopic versus normal intrauterine pregnancyMichael D Mueller
Department of Obstetrics and Gynecology, University of Bern, Bern, Switzerland
Fertil Steril 81:1106-11. 2004..To evaluate whether the serum concentrations of novel placental markers and nonplacental markers differ in ectopic pregnancy when compared with normal intrauterine pregnancy...
Progestins activate vascular endothelial growth factor gene transcription in endometrial adenocarcinoma cellsMichael D Mueller
Department of Obstetrics and Gynecology, Inselspital, University of Bern, Bern, Switzerland
Fertil Steril 79:386-92. 2003..To determine whether progestins activate vascular endothelial growth factor (VEGF) gene transcription in endometrial adenocarcinoma cells...
Epithelial neutrophil-activating peptide 78 concentrations are elevated in the peritoneal fluid of women with endometriosisMichael D Mueller
Department of Obstetrics and Gynecology, Inselspital, University of Bern, Bern, Switzerland
Fertil Steril 79:815-20. 2003..To investigate the presence of epithelial neutrophil-activating peptide 78 (ENA-78) in peritoneal fluid of women with and without endometriosis and to identify the cells that produce this inflammatory protein...
Regulation of vascular endothelial growth factor by tamoxifen in vitro and in vivoMichael D Mueller
Universitats Frauenklinik, Inselspital Bern, Switzerland
Gynecol Obstet Invest 55:119-24. 2003..To evaluate the effects of tamoxifen on human endometrial vascular endothelial growth factor (VEGF) gene expression in vitro and in vivo...
Increased endometrial placenta growth factor (PLGF) gene expression in women with successful implantationAlessandro Santi
Department of Obstetrics and Gynaecology, Inselspital, University of Berne, Berne, Switzerland
Fertil Steril 96:663-8. 2011..To analyze the vascularization of the endometrium via hysteroscopy and to assess its correlation with angiogenic factor gene expression and embryo implantation rate...
Endometriosis-associated nerve fibers, peritoneal fluid cytokine concentrations, and pain in endometriotic lesions from different locationsBrett McKinnon
Department of Obstetrics and Gynecology, Inselspital, Berne University Hospital, University of Berne, Berne, Switzerland
Fertil Steril 97:373-80. 2012..To assess the relationship between endometriotic lesions with associated nerve fibers with both pain and peritoneal fluid (PF) cytokine concentrations based on lesion location...
PAPP-A and osteoprotegerin, together with interleukin-8 and RANTES, are elevated in the peritoneal fluid of women with endometriosisNick A Bersinger
Endometriosis Centre, Department of Obstetrics and Gynaecology, University of Berne, Switzerland
Am J Obstet Gynecol 195:103-8. 2006....
Increased ENA-78 in the follicular fluid of patients with endometriosisDorothea M Wunder
Department of Obstetrics and Gynaecology, University of Berne, Switzerland
Acta Obstet Gynecol Scand 85:336-42. 2006..The aim of the study was to investigate the concentrations of chemokines and proinflammatory cytokines in the follicular fluid of patients with and without endometriosis...
Peroxisome proliferating activating receptor gamma-independent attenuation of interleukin 6 and interleukin 8 secretion from primary endometrial stromal cells by thiazolidinedionesBrett McKinnon
Department of Obstetrics and Gynecology, Inselspital, Berne University Hospital, University of Berne, Berne, Switzerland
Fertil Steril 97:657-64. 2012....
Gene expression in cultured endometrium from women with different outcomes following IVFNick A Bersinger
Department of Obstetrics and Gynaecology, Inselspital, Berne University Hospital, University of Berne, Murtenstrasse 35, Berne CH 3010, Switzerland
Mol Hum Reprod 14:475-84. 2008....
Dose-response effect of interleukin (IL)-1β, tumour necrosis factor (TNF)-α, and interferon-γ on the in vitro production of epithelial neutrophil activating peptide-78 (ENA-78), IL-8, and IL-6 by human endometrial stromal cellsNick A Bersinger
Department of Obstetrics and Gynaecology, University of Berne, Berne, Switzerland
Arch Gynecol Obstet 283:1291-6. 2011..The aim of the study was the analysis of the production of ENA-78, IL-6 and IL-8 by cultured human endometrial stromal cells in the presence of varying concentrations of IL-1β, TNF-α, and interferon-γ...
Painful love-"hispareunia" after sling erosion of the female partnerStefan Mohr
University Hospital of Bern and University of Bern Department of Urogynaecology, Gynaecology, Frauenklinik, Inselspital, Bern, Switzerland
J Sex Med 8:1740-6. 2011..Symptoms may include vaginal discharge, infections, postcoital bleeding, and alterations of the sexual function. Little is known about the effect of sling erosion on the sexual function of the male partner...
Basal and cytokine-stimulated production of epithelial neutrophil activating peptide-78 (ENA-78) and interleukin-8 (IL-8) by cultured human endometrial epithelial and stromal cellsNick A Bersinger
Department of Obstetrics and Gynecology, University of Berne, Berne, Switzerland
Fertil Steril 89:1530-6. 2008..To analyze the constitutive production of epithelial neutrophil activating peptide 78 (ENA-78) and interleukin-8 (IL-8) by epithelial cells and the response of these cells to cytokine stimulation...
Clinical scoring system for vulvar lichen sclerosusAndreas R Günthert
Department of Gynecology and Obstetrics, Inselspital, Bern University Hospital, and University of Bern, Bern, Switzerland
J Sex Med 9:2342-50. 2012..Advanced disease severely affects quality of life like sexual disorders and is also associated with an increased risk of vulvar cancer...
PPAR-gamma expression in peritoneal endometriotic lesions correlates with pain experienced by patientsBrett McKinnon
Department of Obstetrics and Gynecology, Inselspital, Berne University Hospital, University of Berne, Berne, Switzerland
Fertil Steril 93:293-6. 2010..In peritoneal endometriotic lesions, the expression of peroxisome proliferation-activated receptor gamma, a nuclear receptor with antiinflammatory and neuroprotective roles, is positively correlated with the pain reported by patients...
Steroids and protein markers in the follicular fluid as indicators of oocyte quality in patients with and without endometriosisDorothea M Wunder
Department of Obstetrics and Gynaecology, University of Berne, Switzerland
J Assist Reprod Genet 22:257-64. 2005..To investigate the concentrations of steroid hormones (estradiol, progesterone), pregnancy-associated protein-A, IGF-binding protein-4 and leptin in the follicular fluid of infertile patients with and without endometriosis...
Laparoscopy or laparotomy? A comparison of 240 patients with early-stage endometrial cancerAlessandro Santi
Department of Obstetrics and Gynecology, Inselspital, Bern University Hospital and University of Bern, Effingerstrasse 102, CH 3012, Bern, Switzerland
Surg Endosc 24:939-43. 2010..This study aimed to compare the safety and efficacy of laparoscopy and laparotomy in the surgical treatment of early endometrial cancer, especially in obese women...
Sexual and organ function in patients with symptomatic prolapse: are pessaries helpful?Annette Kuhn
Department of Gynecology, Division of Urogynecology, Inselspital and University of Bern, Bern, Switzerland
Fertil Steril 91:1914-8. 2009..To evaluate quality of life and pelvic organ and sexual function before and during pessary use in patients with symptomatic pelvic organ prolapse and to determine reasons which lead to cessation of pessary use...
Sexual function after suburethral sling removal for dyspareuniaAnnette Kuhn
Department of Obstetrics and Gynaecology, Bern University Hospital and University of Bern, Effingerstr 102, CH 3010 Bern, Switzerland
Surg Endosc 23:765-8. 2009..Recent studies have reported varying degrees of sexual impairment after TVT insertion ranging from 0% to 15% including dyspareunia...
Correction of erosion after suburethral sling insertion for stress incontinence: results and related sexual functionAnnette Kuhn
Department of Gynaecology, University Hospital Bern and University of Bern, Switzerland
Eur Urol 56:371-6. 2009..Suburethral slings are commonly used for the surgical treatment of female stress incontinence; occasionally they can cause erosion and dyspareunia...
Out of Eastern Africa: defibulation and sexual function in woman with female genital mutilationElke Krause
Department of Urogynaecology, Frauenklinik, Inselspital, University of Bern, Bern, Switzerland
J Sex Med 8:1420-5. 2011....
Tubal sterilization: complications of laparoscopy and minilaparotomyAlexander W Huber
Department of Obstetrics and Gynecology, University of Berne, Inselspital, Effingerstrasse 102, Berne 3010, Switzerland
Eur J Obstet Gynecol Reprod Biol 134:105-9. 2007..To evaluate whether intra- and post-operative morbidity varies according to the method used for female sterilization...
Quality of life 15 years after sex reassignment surgery for transsexualismAnnette Kuhn
Frauenklinik, University Hospital and University of Bern, Bern, Switzerland
Fertil Steril 92:1685-1689.e3. 2009..To evaluate quality of life and patients' satisfaction in transsexual patients (TS) after sex reassignment operation compared with healthy controls...
Bulking agents: an analysis of 500 cases and review of the literatureStefan Mohr
Department of Obstetrics and Gynecology, Inselspital, Bern University Hospital and University of Bern, Effingerstr 102, 3010 Bern, Switzerland
Int Urogynecol J 24:241-7. 2013..The aim of this study was to prospectively analyze the efficacy and safety of bulking agents in the setting of a tertiary referral center...
[New insights into the pathophysiology of endometriosis]Corinne Neukomm
Kliniken und Polikliniken für Frauenheilkunde, Universitätsspital Insel, Bern, Switzerland
Gynakol Geburtshilfliche Rundsch 47:113-7. 2007..This article gives an overview of the different factors involved in the development, growth and progression of endometriosis...
Sexual function after sacrocolpopexyAnnette Kuhn
Department of Gynaecology, Frauenklinik, Inselspital, Switzerland
J Sex Med 7:4018-23. 2010..Sacrocolpopexy is the gold standard of surgical treatment for apical prolapse in fit, sexually active patients. Few data exist which determine sexual function after sacrocolpopexy...
Male and female sexual function after surgical repair of female organ prolapseAnnette Kuhn
University Hospital and University of Bern, Urogynaecology, Bern, Switzerland
J Sex Med 6:1324-34. 2009..Few data are available referring to male and female sexual function after prolapse repair of symptomatic pelvic organ...
Altered expression of a cell-cycle suppressor gene, Tob-1, in endometriotic cells by cDNA array analysesDan I Lebovic
Reproductive Endocrinology Division, Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, Michigan, USA
Fertil Steril 78:849-54. 2002..These findings are the first to associate IL-1beta with an alteration of cell-cycle gene expression in cells derived from endometriotic implants...
Seasonality in human semen quality of smokers and non-smokers: effect of temperatureRobert Künzle
University Department of Clinical Research, Inselspital KKL G3 825, Berne CH 3010, Switzerland
Asian J Androl 6:243-7. 2004..To analyse the possible effect of seasonal variation on semen parameters...
Angiogenic effects of norplant contraception on endometrial histology and uterine bleedingElizabeth A Pritts
Center for Reproductive Sciences, Department of Obstetrics, Gynecology and Reproductive Sciences, 513 Parnassus, Health Sciences West 1656, University of California, San Francisco, San Francisco, California 94143-0556, USA
J Clin Endocrinol Metab 90:2142-7. 2005..Irregular bleeding with Norplant use appears to reflect paracrine-mediated effects on vascular function by angiogenic factors, such as VEGF...
"Kissing ovaries": a sonographic sign of moderate to severe endometriosisFabio Ghezzi
Department of Obstetrics and Gynecology, University of Insubria, Del Ponte Hospital, Varese, Italy
Fertil Steril 83:143-7. 2005..To evaluate whether the presence of kissing ovaries at ultrasound is a marker for endometriosis and whether it correlates with the severity of the disease...
PPAR-gamma receptor ligand induces regression of endometrial explants in baboons: a prospective, randomized, placebo- and drug-controlled studyDan I Lebovic
Reproductive Endocrinology Division, Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, Michigan 48109, USA
Fertil Steril 88:1108-19. 2007..To determine the effects of a thiazolidinedione (TZD) agonist of peroxisome proliferator-activated receptor (PPAR)-gamma, rosiglitazone, in a baboon model of established endometriosis...
Outcome of laparoscopic ureterolysis for ureteral endometriosisFabio Ghezzi
Department of Obstetrics and Gynecology, University of Insubria, Del Ponte Hospital, Varese, Italy
Fertil Steril 86:418-22. 2006..To evaluate the adequacy of laparoscopic ureterolysis as a primary treatment option for ureteral endometriosis...
Expression of mannose-binding lectin in the peritoneal fluid of women with and without endometriosisShahryar K Kavoussi
Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, University of Michigan Endometriosis Center, Ann Arbor, Michigan, USA
Fertil Steril 85:1526-8. 2006..Mannose-binding lectin (MBL) modulates inflammation and usually enhances clearance of apoptotic cells. We observed that the concentration and total amount of peritoneal fluid MBL does not differ in patients with and without endometriosis...
Angiogenic factors in endometriosisRobert N Taylor
Center for Reproductive Sciences, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco, 94143 0556, USA
Ann N Y Acad Sci 955:89-100; discussion 118, 396-406. 2002..We postulate that interference with angiogenic principles expressed in the peritoneum may constitute novel therapeutic opportunities for the prevention, amelioration, or treatment of pelvic endometriosis...
