Christian Mueller

Summary

Affiliation: University Hospital
Country: Switzerland

Publications

  1. ncbi request reprint The use of B-type natriuretic peptide in the management of patients with diabetes and acute dyspnoea
    C Mueller
    Department of Internal Medicine, University Hospital, Petersgraben 4, 4031, Basel, Switzerland
    Diabetologia 49:629-36. 2006
  2. ncbi request reprint The use of B-type natriuretic peptide in the management of patients with atrial fibrillation and dyspnea
    Tobias Breidthardt
    Department of Internal Medicine, University of Basel, University Hospital, Switzerland
    Int J Cardiol 136:193-9. 2009
  3. pmc Impact of mannose-binding lectin deficiency on radiocontrast-induced renal dysfunction: a post-hoc analysis of a multicenter randomized controlled trial
    Michael Osthoff
    Laboratory of Clinical Immunology, Department of Biomedicine, University Hospital Basel, Basel, Switzerland
    BMC Nephrol 13:99. 2012
  4. pmc Utile or futile: biomarkers in the ICU
    Cathrin Balmelli
    Department of Internal Medicine, University Hospital, Petersgraben 4, CH 4031 Basel, Switzerland
    Crit Care 15:131. 2011
  5. doi request reprint High-sensitivity cardiac troponin in the distinction of acute myocardial infarction from acute cardiac noncoronary artery disease
    Philip Haaf
    Department of Internal Medicine, University Hospital Basel, Basel, Switzerland
    Circulation 126:31-40. 2012
  6. doi request reprint New ESC guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation
    C Muller
    University Hospital, Petersgraben 4, Basel, Switzerland
    Swiss Med Wkly 142:w13514. 2012
  7. doi request reprint Direct comparison of three natriuretic peptides for prediction of short- and long-term mortality in patients with community-acquired pneumonia
    Albina Nowak
    Department of Internal Medicine, University Hospital Basel, Basel, Switzerland
    Chest 141:974-82. 2012
  8. pmc Pro-adrenomedullin to predict severity and outcome in community-acquired pneumonia [ISRCTN04176397]
    Mirjam Christ-Crain
    Department of Internal Medicine, University Hospital Basel, Switzerland
    Crit Care 10:R96. 2006
  9. ncbi request reprint The use of B-type natriuretic peptide in the diagnosis of acute dyspnoea
    Christian Mueller
    Department of Internal Medicine, University Hospital Basel, Switzerland
    Clin Lab 51:5-9. 2005
  10. ncbi request reprint Inflammation and long-term mortality in acute congestive heart failure
    Christian Mueller
    Department of Internal Medicine, University of Basel, University Hospital, Basel, Switzerland
    Am Heart J 151:845-50. 2006

Detail Information

Publications136 found, 100 shown here

  1. ncbi request reprint The use of B-type natriuretic peptide in the management of patients with diabetes and acute dyspnoea
    C Mueller
    Department of Internal Medicine, University Hospital, Petersgraben 4, 4031, Basel, Switzerland
    Diabetologia 49:629-36. 2006
    ..The aim of this study was to determine the impact of measurement of B-type natriuretic peptide (BNP) levels on the management of patients with diabetes presenting with acute dyspnoea...
  2. ncbi request reprint The use of B-type natriuretic peptide in the management of patients with atrial fibrillation and dyspnea
    Tobias Breidthardt
    Department of Internal Medicine, University of Basel, University Hospital, Switzerland
    Int J Cardiol 136:193-9. 2009
    ..022) and induced lower total treatment costs ($4790 [1260-9387] versus $7179 [4311-13173]; P=0.016). In conclusion, the use of BNP seems to improve the management of patients with AF presenting with dyspnea...
  3. pmc Impact of mannose-binding lectin deficiency on radiocontrast-induced renal dysfunction: a post-hoc analysis of a multicenter randomized controlled trial
    Michael Osthoff
    Laboratory of Clinical Immunology, Department of Biomedicine, University Hospital Basel, Basel, Switzerland
    BMC Nephrol 13:99. 2012
    ..The aim of the present study was to investigate the association of MBL deficiency with radiocontrast-induced renal dysfunction in a large prospective cohort...
  4. pmc Utile or futile: biomarkers in the ICU
    Cathrin Balmelli
    Department of Internal Medicine, University Hospital, Petersgraben 4, CH 4031 Basel, Switzerland
    Crit Care 15:131. 2011
    ....
  5. doi request reprint High-sensitivity cardiac troponin in the distinction of acute myocardial infarction from acute cardiac noncoronary artery disease
    Philip Haaf
    Department of Internal Medicine, University Hospital Basel, Basel, Switzerland
    Circulation 126:31-40. 2012
    ..We hypothesized that high-sensitivity cardiac troponin (hs-cTn) and its early change are useful in distinguishing acute myocardial infarction (AMI) from acute cardiac noncoronary artery disease...
  6. doi request reprint New ESC guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation
    C Muller
    University Hospital, Petersgraben 4, Basel, Switzerland
    Swiss Med Wkly 142:w13514. 2012
    ..Certainly, application of the principles highlighted in there will help them in their daily clinical work...
  7. doi request reprint Direct comparison of three natriuretic peptides for prediction of short- and long-term mortality in patients with community-acquired pneumonia
    Albina Nowak
    Department of Internal Medicine, University Hospital Basel, Basel, Switzerland
    Chest 141:974-82. 2012
    ..Early and accurate risk stratification for patients with community-acquired pneumonia (CAP) is an unmet clinical need...
  8. pmc Pro-adrenomedullin to predict severity and outcome in community-acquired pneumonia [ISRCTN04176397]
    Mirjam Christ-Crain
    Department of Internal Medicine, University Hospital Basel, Switzerland
    Crit Care 10:R96. 2006
    ..A major cause of sepsis is community-acquired pneumonia (CAP). The aim of this study was to investigate the value of proADM levels for severity assessment and outcome prediction in CAP...
  9. ncbi request reprint The use of B-type natriuretic peptide in the diagnosis of acute dyspnoea
    Christian Mueller
    Department of Internal Medicine, University Hospital Basel, Switzerland
    Clin Lab 51:5-9. 2005
    ....
  10. ncbi request reprint Inflammation and long-term mortality in acute congestive heart failure
    Christian Mueller
    Department of Internal Medicine, University of Basel, University Hospital, Basel, Switzerland
    Am Heart J 151:845-50. 2006
    ..Systemic inflammation has long been recognized as a precipitator of acute congestive heart failure (CHF). The impact of inflammation on prognosis in acute CHF, however, is unknown...
  11. ncbi request reprint Use of B-type natriuretic peptide in the management of acute dyspnea in patients with pulmonary disease
    Christian Mueller
    Medical Division A, Department of Internal Medicine, University Hospital, University of Basel, Basel, Switzerland
    Am Heart J 151:471-7. 2006
    ..The impact of B-type natriuretic peptide (BNP) measurements on the management of patients with pulmonary disease and acute dyspnea remains to be defined...
  12. ncbi request reprint Prevention of contrast nephropathy in critically ill patients using acetylcysteine and theophylline
    C Mueller
    Department of Internal Medicine, University Hospital of Basel, Basel, Switzerland
    Int J Artif Organs 27:1066-9. 2004
    ..Although its benefit compared with periprocedural hydration alone seems less well established, theophylline is a particularly attractive option for emergency procedures...
  13. ncbi request reprint Emergency diagnosis of congestive heart failure: impact of signs and symptoms
    Christian Mueller
    University of Basel, University Hospital, Department of Internal Medicine, Basel, Switzerland
    Can J Cardiol 21:921-4. 2005
    ..The most useful features in the diagnosis of congestive heart failure (CHF) have been poorly investigated...
  14. ncbi request reprint Incidence of contrast nephropathy in patients receiving comprehensive intravenous and oral hydration
    Christian Mueller
    Department of Internal Medicine, University Hospital of Basel, Switzerland
    Swiss Med Wkly 135:286-90. 2005
    ..Contrast-induced nephropathy (CIN) remains a major complication of percutaneous coronary interventions (PCI) and a common cause of acute renal failure. The most effective preventive strategy is unknown...
  15. ncbi request reprint Procalcitonin and the early diagnosis of infective endocarditis
    Christian Mueller
    Department of Internal Medicine, University Hospital Basel, Basel, Switzerland
    Circulation 109:1707-10. 2004
    ..Variability in the clinical presentation of infective endocarditis (IE) makes the diagnosis a clinical challenge. We hypothesized that serum procalcitonin, a marker of systemic bacterial infection, might be helpful in its diagnosis...
  16. ncbi request reprint Cost-effectiveness of B-type natriuretic peptide testing in patients with acute dyspnea
    Christian Mueller
    Department of Internal Medicine, University Hospital, University of Basel, Basel, Switzerland
    Arch Intern Med 166:1081-7. 2006
    ..B-type natriuretic peptide (BNP) is a quantitative marker of heart failure that seems to be helpful in its diagnosis...
  17. ncbi request reprint The use of B-type natriuretic peptides in the intensive care unit
    Christian Mueller
    University Hospital, Basel, Switzerland
    Congest Heart Fail 14:43-5. 2008
    ....
  18. ncbi request reprint Cost-effectiveness of B-type natriuretic peptide testing
    Christian Mueller
    Department of Internal Medicine, University Hospital, Basel, Switzerland
    Congest Heart Fail 14:35-7. 2008
    ..For the remaining and, in part, evolving indications, further studies are needed to assess cost-effectiveness...
  19. ncbi request reprint Risk stratification in acute decompensated heart failure: the role of cardiac troponin
    Christian Mueller
    University of Basel and Internal Medicine at University Hospital Basel, Basel, Switzerland
    Nat Clin Pract Cardiovasc Med 5:680-1. 2008
    ..0% vs 2.7%; P<0.001). Future studies need to define which treatment changes could improve outcome in troponin-positive patients with acute decompensated heart failure...
  20. ncbi request reprint Biomarkers: past, present, and future
    Christian Mueller
    Department of Internal Medicine, University Hospital, Basel, Switzerland
    Swiss Med Wkly 138:225-9. 2008
    ..Although these may look like unrelated medical challenges, recent clinical research in these areas by our groups and others has opened up opportunities and challenges that seem fundamental for biomarkers in general...
  21. doi request reprint B-type natriuretic peptides for the evaluation of exercise intolerance
    Christian Mueller
    Department of Internal Medicine, University Hospital Basel, Switzerland
    Am J Med 122:265-72. 2009
    ..This study sought to assess the utility of B-type natriuretic peptide (BNP) and N-terminal-pro-B-type natriuretic peptide (NT-proBNP) for the identification of a cardiocirculatory exercise limitation...
  22. ncbi request reprint [Clinical utility of natriuretic peptdies in dyspnea]
    Christian Muller
    Klinik fur Innere Medizin, Universitatsspital Basel
    Ther Umsch 66:649-52. 2009
    ..Accordingly, measurement of NPs should be part of the work-up in most if not all patients with dyspnea...
  23. ncbi request reprint The integration of BNP and NT-proBNP into clinical medicine
    Christian Mueller
    Department of Internal Medicine, University Hospital, Petersgraben 4, CH 4031 Basel, Switzerland
    Swiss Med Wkly 137:4-12. 2007
    ....
  24. ncbi request reprint What cardiologists do need to know about procalcitonin
    Christian Mueller
    Department of Internal Medicine, University Hospital Basel, Switzerland
    Clin Lab 51:1-4. 2005
    ..49 (p < 0.001), as compared to the standard group. Thus, using a sensitive assay, procalcitonin-guidance substantially and safely reduced antibiotic usage in LRTI...
  25. ncbi request reprint Right bundle branch block and long-term mortality in patients with acute congestive heart failure
    C Mueller
    Department of Internal Medicine, University Hospital Basel, Petersgraben 4, Basel, Switzerland
    J Intern Med 260:421-8. 2006
    ..Risk stratification in acute congestive heart failure (ACHF) is poorly defined. The aim of the present study was to assess the impact of right bundle brunch block (RBBB) on long-term mortality in patients presenting with ACHF...
  26. ncbi request reprint The impact of platelet count on mortality in unstable angina/non-ST-segment elevation myocardial infarction
    Christian Mueller
    Herz Zentrum, Bad Krozingen, Germany
    Am Heart J 151:1214.e1-7. 2006
    ..Therefore, we sought to determine the impact of platelet count on long-term outcome in unstable angina/non-ST-segment elevation myocardial infarction (UA/NSTEMI) receiving contemporary treatment...
  27. ncbi request reprint Prognostic value of quantitative troponin T measurements in unstable angina/non-ST-segment elevation acute myocardial infarction treated early and predominantly with percutaneous coronary intervention
    Christian Mueller
    Herz Zentrum, Bad Krozingen, Germany
    Am J Med 117:897-902. 2004
    ..To evaluate the effect of baseline cardiac troponin T measurements on in-hospital and long-term outcomes in patients with unstable angina/non-ST-segment elevation myocardial infarction who are treated with an early invasive strategy...
  28. ncbi request reprint Use of B-type natriuretic peptide in the evaluation and management of acute dyspnea
    Christian Mueller
    Department of Internal Medicine, Medical Division A, University of Basel, University Hospital, Basel, Switzerland
    N Engl J Med 350:647-54. 2004
    ..B-type natriuretic peptide levels are higher in patients with congestive heart failure than in patients with dyspnea from other causes...
  29. ncbi request reprint Cost-effectiveness of intracoronary ultrasound for percutaneous coronary interventions
    Christian Mueller
    Herz Zentrum Bad Krozingen, Krozingen, Germany
    Am J Cardiol 91:143-7. 2003
    ..In 55.3% of bootstrapping replications, IVUS was less expensive and more effective. In conclusion, when used in a provisional stenting strategy, routine IVUS imaging is cost-saving half the time...
  30. ncbi request reprint A randomized comparison of clopidogrel and aspirin versus ticlopidine and aspirin after the placement of coronary artery stents
    Christian Mueller
    Bad Krozingen Heart Center, Bad Krozingen, Germany
    J Am Coll Cardiol 41:969-73. 2003
    ..The aim of the present study was to compare clopidogrel and ticlopidine after coronary stenting with regard to cardiovascular death during long-term follow-up...
  31. ncbi request reprint Operator experience and long term outcome after percutaneous coronary intervention
    Christian Mueller
    Medizinische Universitätsklinik Basel, Basel, Switzerland
    Can J Cardiol 19:1047-51. 2003
    ..To investigate the impact of operator experience on long term outcome of patients undergoing percutaneous coronary intervention (PCI)...
  32. ncbi request reprint [B-type natriuretic peptide--current use in the diagnosis and management of heart failure]
    Christian Muller
    Departemente Innere Medizin, Medizinische Universitatsklinik, Basel, Switzerland
    Herz 28:374-9. 2003
    ..In this review, the utility of BNP in different clinical settings will be discussed...
  33. pmc White blood cell count and long term mortality after non-ST elevation acute coronary syndrome treated with very early revascularisation
    C Mueller
    Herz Zentrum Bad Krozingen, Bad Krozingen, Germany
    Heart 89:389-92. 2003
    ..To evaluate the predictive value of white blood cell count (WBC) for short and long term mortality in patients with non-ST elevation acute coronary syndromes (NSTACS) treated with a very early invasive strategy...
  34. ncbi request reprint Previous cytomegalovirus infection and restenosis after aggressive angioplasty with provisional stenting
    Christian Mueller
    Herz Zentrum Bad Krozingen, Germany
    J Interv Cardiol 16:307-13. 2003
    ..The aim of this study was to determine the impact of previous with cytomegalovirus (CMV) on restenosis after aggressive angioplasty with provisional stenting...
  35. ncbi request reprint Impact of intracoronary ultrasound guidance on long-term outcome of percutaneous coronary interventions in diabetics--insights from the randomized SIPS trial
    Christian Mueller
    Herz Zentrum Bad Krozingen, Germany
    Swiss Med Wkly 132:279-84. 2002
    ....
  36. ncbi request reprint Women do have an improved long-term outcome after non-ST-elevation acute coronary syndromes treated very early and predominantly with percutaneous coronary intervention: a prospective study in 1,450 consecutive patients
    Christian Mueller
    Bad Krozingen Heart Center, Bad Krozingen, Germany
    J Am Coll Cardiol 40:245-50. 2002
    ..This study sought to assess gender-based differences in long-term outcome after very early aggressive revascularization for non-ST-elevation acute coronary syndromes (NSTACS)...
  37. ncbi request reprint Use of B-type natriuretic peptide for the management of women with dyspnea
    Christian Mueller
    Department of Internal Medicine, Medical Division, University of Basel, University Hospital, Basel, Switzerland
    Am J Cardiol 94:1510-4. 2004
    ..165). Thus, used in conjunction with other clinical information, rapid measurement of BNP decreased time to discharge and total cost of treatment in women who presented with acute dyspnea...
  38. ncbi request reprint Prognostic value of the admission electrocardiogram in patients with unstable angina/non-ST-segment elevation myocardial infarction treated with very early revascularization
    Christian Mueller
    University Hospital, Basel, Switzerland
    Am J Med 117:145-50. 2004
    ..The goals of this study were to determine if very early revascularization might ameliorate the adverse prognosis associated with ST-segment depression in patients with unstable angina/non-ST-segment elevation myocardial infarction...
  39. ncbi request reprint [Does red wine protect from myocardial infarction]
    Ch Muller
    Departement Innere Medizin, Universitätsklinik Basel
    Praxis (Bern 1994) 93:1143-6. 2004
  40. pmc Renal function and long term mortality after unstable angina/non-ST segment elevation myocardial infarction treated very early and predominantly with percutaneous coronary intervention
    C Mueller
    Herz Zentrum, Bad Krozingen, Germany
    Heart 90:902-7. 2004
    ..To quantify the impact of baseline renal function on in-hospital and long term mortality in patients with unstable angina/non-ST elevation acute myocardial infarction (UA/NSTEMI) treated with a very early invasive strategy...
  41. ncbi request reprint Impact of diabetes mellitus on long-term outcome after unstable angina and non-ST-segment elevation myocardial infarction treated with a very early invasive strategy
    C Muller
    The Heart Center Bad Krozingen, Germany
    Diabetologia 47:1188-95. 2004
    ..We sought to evaluate the impact of diabetes mellitus on long-term outcome in patients with unstable angina and non-ST-segment elevation myocardial infarction treated with a very early invasive strategy...
  42. ncbi request reprint Female sex and risk of contrast nephropathy after percutaneous coronary intervention
    Christian Mueller
    Herz Zentrum Bad Krozingen, Bad Krozingen, Germany
    Can J Cardiol 20:505-9. 2004
    ..The reason for this difference in outcome is unknown. Contrast nephropathy (CN) remains a major complication of PCI and a common cause of acute renal failure...
  43. ncbi request reprint Prevention of contrast media-associated nephropathy: randomized comparison of 2 hydration regimens in 1620 patients undergoing coronary angioplasty
    Christian Mueller
    Herz Zentrum, Bad Krozingen, Germany
    Arch Intern Med 162:329-36. 2002
    ..The administration of radiographic contrast agents remains an important cause of acute renal failure. The optimal infusion for hydration has not been evaluated...
  44. ncbi request reprint B-type natriuretic peptide for acute dyspnea in patients with kidney disease: insights from a randomized comparison
    Christian Mueller
    University of Basel, University Hospital, Department of Internal Medicine, Medical Division A, Basel, Switzerland
    Kidney Int 67:278-84. 2005
    ..However, kidney disease results in elevated BNP levels independently of CHF. Accordingly, the impact of kidney disease on the benefit of BNP testing needs to be scrutinized...
  45. doi request reprint N-terminal pro B-type natriuretic peptide in the early evaluation of suspected acute myocardial infarction
    Philip Haaf
    Department of Internal Medicine, University Hospital, Basel, Switzerland
    Am J Med 124:731-9. 2011
    ..As ischemia precedes necrosis in acute myocardial infarction, we hypothesized that NT-proBNP might be useful in the early diagnosis and risk stratification of patients with suspected acute myocardial infarction...
  46. ncbi request reprint Use of B-type natriuretic peptide in the risk stratification of acute exacerbations of COPD
    Daiana Stolz
    Clinic for Pneumology and Respiratory Cell Research, University Hospital Basel, Switzerland
    Chest 133:1088-94. 2008
    ..In patients with COPD, prognosis might be determined at least in part by the extent of cardiac stress induced by hypoxia and pulmonary arterial hypertension...
  47. pmc Diagnostic and prognostic accuracy of clinical and laboratory parameters in community-acquired pneumonia
    Beat Muller
    Departments of Internal Medicine, University Hospital, Petersgraben 4, CH 4031, Basel, Switzerland
    BMC Infect Dis 7:10. 2007
    ..This study aims to evaluate the diagnostic and prognostic accuracy of clinical signs and symptoms and laboratory biomarkers for CAP...
  48. doi request reprint Utility of C-terminal proendothelin in the early diagnosis and risk stratification of patients with suspected acute myocardial infarction
    Philip Haaf
    Department of Internal Medicine, University Hospital, Basel, Switzerland Department of Cardiology, University Hospital, Basel, Switzerland
    Can J Cardiol 30:195-203. 2014
    ..Endothelial dysfunction plays a major role in cardiovascular diseases, including acute myocardial infarction (AMI). However, its quantification has not been available as a clinical tool...
  49. ncbi request reprint Inflammation and long-term mortality after non-ST elevation acute coronary syndrome treated with a very early invasive strategy in 1042 consecutive patients
    Christian Mueller
    Herz Zentrum Bad Krozingen, Germany
    Circulation 105:1412-5. 2002
    ..This study sought to evaluate the predictive value of C-reactive protein (CRP) on long-term mortality in non-ST-elevation acute coronary syndromes (NSTACS) that were treated with a very early aggressive revascularization strategy...
  50. doi request reprint Midregional pro-A-type natriuretic peptide for diagnosis and prognosis in patients with suspected acute myocardial infarction
    Christophe Meune
    Department of Internal Medicine, University Hospital, Basel, Switzerland
    Am J Cardiol 109:1117-23. 2012
    ..388 (p <0.001), 0.425 (p <0.001), and 0.217 (p = 0.007), respectively. In conclusion, MR-proANP improves risk prediction for 360-day mortality/AMI but does not seem to help in the early diagnosis of AMI...
  51. doi request reprint Diagnostic and prognostic impact of copeptin and high-sensitivity cardiac troponin T in patients with pre-existing coronary artery disease and suspected acute myocardial infarction
    Mihael Potocki
    Department of Cardiology, University Hospital Basel, Basel, Switzerland
    Heart 98:558-65. 2012
    ..The early diagnosis of acute myocardial infarction (AMI) can be particularly challenging in patients with known coronary artery disease (CAD) due to pre-existing ECG changes and chronic increases in cardiac troponin (cTn) levels...
  52. doi request reprint Incremental value of high-sensitivity cardiac troponin T for risk prediction in patients with suspected acute myocardial infarction
    Willibald Hochholzer
    Department of Internal Medicine, University Hospital Basel, Switzerland
    Clin Chem 57:1318-26. 2011
    ..We evaluated whether use of a high-sensitivity assay could further improve risk stratification compared with a standard cardiac troponin assay...
  53. doi request reprint Use of neutrophil count in early diagnosis and risk stratification of AMI
    Julia Meissner
    Department of Internal Medicine, University Hospital Basel, Switzerland
    Am J Med 124:534-42. 2011
    ..We hypothesized that neutrophil count might provide incremental value in the early diagnosis and risk stratification of AMI...
  54. doi request reprint Markers of plaque instability in the early diagnosis and risk stratification of acute myocardial infarction
    Nora Schaub
    Department of Internal Medicine, University Hospital Basel, Basel, Switzerland
    Clin Chem 58:246-56. 2012
    ..Plaque erosion and plaque rupture occur early in the pathophysiology of acute myocardial infarction (AMI). We hypothesized that markers of plaque instability might be useful in the early diagnosis and risk stratification of AMI...
  55. pmc Copeptin and risk stratification in patients with acute dyspnea
    Mihael Potocki
    Department of Cardiology, University Hospital, Petersgraben 4, Basel, 4031, Switzerland
    Crit Care 14:R213. 2010
    ..This study investigates the prognostic value of Copeptin, the C-terminal part of the vasopressin prohormone alone and combined to N-terminal pro B-type natriuretic peptide (NT-proBNP) in patients with acute dyspnea...
  56. ncbi request reprint Sex-specific chest pain characteristics in the early diagnosis of acute myocardial infarction
    Maria Rubini Gimenez
    Department of Cardiology, University Hospital Basel, Basel, Switzerland2Servicio de Urgencias y Pneumologia, CIBER de Enfermedades Raras, Carles III Institute for Health, Hospital del Mar Institut Municipal d Investigació Mèdica, Barcelona, Spain
    JAMA Intern Med 174:241-9. 2014
    ..OBJECTIVE To improve the management of suspected AMI in women by exploring sex-specific CPCs...
  57. doi request reprint Normal presenting levels of high-sensitivity troponin and myocardial infarction
    Rebeca Hoeller
    Department of Cardiology, University Hospital Basel, Basel, Switzerland
    Heart 99:1567-72. 2013
    ..To analyse whether levels of high-sensitivity cardiac troponin (hs-cTn) below their respective 99th percentile can be used as a single parameter to rule out acute myocardial infarction (AMI) at presentation...
  58. doi request reprint Introduction of high-sensitivity troponin assays: impact on myocardial infarction incidence and prognosis
    Tobias Reichlin
    Department of Cardiology, University Hospital, Basel, Switzerland
    Am J Med 125:1205-1213.e1. 2012
    ..The study objective was to compare the incidence and prognosis of acute myocardial infarction when using high-sensitivity cardiac troponin assays instead of a standard cardiac troponin assay for the diagnosis of acute myocardial infarction...
  59. doi request reprint B-type natriuretic peptide in the early diagnosis and risk stratification of acute chest pain
    Philip Haaf
    Department of Internal Medicine, University Hospital, Basel, Switzerland
    Am J Med 124:444-52. 2011
    ..As ischemia precedes necrosis in acute myocardial infarction, we hypothesized that BNP might be useful in the early diagnosis and risk stratification of patients with acute chest pain...
  60. ncbi request reprint Growth differentiation factor-15 in the early diagnosis and risk stratification of patients with acute chest pain
    Nora Schaub
    Department of Internal Medicine, University Hospital, Basel, Switzerland
    Clin Chem 58:441-9. 2012
    ..Growth differentiation factor-15 (GDF-15) is a stress-responsive marker that might aid in the early diagnosis and risk stratification of patients with suspected acute myocardial infarction (AMI)...
  61. doi request reprint Impact of history of heart failure on diagnostic and prognostic value of BNP: results from the B-type Natriuretic Peptide for Acute Shortness of Breath Evaluation (BASEL) study
    Tujana Boldanova
    Department of Internal Medicine, University of Basel, University Hospital, Switzerland
    Int J Cardiol 142:265-72. 2010
    ....
  62. ncbi request reprint Diagnostic and prognostic value of uric acid in patients with acute dyspnea
    Tobias Reichlin
    Department of Internal Medicine, University Hospital Basel, Switzerland
    Am J Med 122:1054.e7-1054.e14. 2009
    ..Uric acid was shown to predict outcome in patients with stable chronic heart failure. Its impact in patients admitted in the Emergency Department with acute dyspnea, however, remains unknown...
  63. doi request reprint Central venous pressure at emergency room presentation predicts cardiac rehospitalization in patients with decompensated heart failure
    Heiko Uthoff
    Department of Angiology, University Hospital, Basel, Switzerland
    Eur J Heart Fail 12:469-76. 2010
    ..To investigate the relationship between central venous pressure (CVP) at presentation to the emergency room (ER) and the risk of cardiac rehospitalization and mortality in patients with decompensated heart failure (DHF)...
  64. ncbi request reprint Multimarker strategy for risk prediction in patients presenting with acute dyspnea to the emergency department
    Michael Christ
    Department of Internal Medicine, University Hospital, Petersgraben 4, CH 4031 Basel, Switzerland
    Int J Cardiol 126:73-8. 2008
    ....
  65. ncbi request reprint Mid-regional pro-adrenomedullin in the early evaluation of acute chest pain patients
    Philip Haaf
    Department of Internal Medicine, Division of Cardiology, University Hospital, Basel, Switzerland
    Int J Cardiol 168:1048-55. 2013
    ....
  66. doi request reprint Pathophysiology of lower extremity edema in acute heart failure revisited
    Tobias Breidthardt
    Department of Internal Medicine, University Hospital, Basel, Switzerland
    Am J Med 125:1124.e1-1124.e8. 2012
    ..The pathophysiology and key determinants of lower extremity edema in patients with acute heart failure are poorly investigated...
  67. ncbi request reprint One-hour rule-out and rule-in of acute myocardial infarction using high-sensitivity cardiac troponin T
    Tobias Reichlin
    Department of Cardiology, University Hospital Basel, Switzerland
    Arch Intern Med 172:1211-8. 2012
    ..Our objective was to develop and validate an algorithm for rapid rule-out and rule-in of AMI...
  68. doi request reprint How safe is the outpatient management of patients with acute chest pain and mildly increased cardiac troponin concentrations?
    Christophe Meune
    Department of Internal Medicine, University Hospital, Basel, Switzerland
    Clin Chem 58:916-24. 2012
    ..The appropriate management of patients discharged from the emergency department (ED) with increased high-sensitivity cardiac troponin T (hs-cTnT) but normal or borderline-high conventional cardiac troponin concentrations is unknown...
  69. ncbi request reprint Early diagnosis of acute myocardial infarction in patients with pre-existing coronary artery disease using more sensitive cardiac troponin assays
    Miriam Reiter
    Department of Internal Medicine, University Hospital, Petersgraben 4, CH 4031 Basel, Switzerland
    Eur Heart J 33:988-97. 2012
    ..We sought to examine the diagnostic and prognostic utility of sensitive cardiac troponin (cTn) assays in patients with pre-existing coronary artery disease (CAD)...
  70. doi request reprint Determinants of high-sensitivity troponin T among patients with a noncardiac cause of chest pain
    Affan Irfan
    Department of Internal Medicine, University Hospital Basel, Switzerland
    Am J Med 125:491-498.e1. 2012
    ..It is unknown to what extent noncardiac causes, including renal dysfunction, may contribute to high-sensitivity cardiac troponin T levels...
  71. doi request reprint Systolic blood pressure at Emergency Department presentation and 1-year mortality in acute chest pain patients
    Affan Irfan
    Department of Internal Medicine, University Hospital, Basel, Switzerland
    Eur J Intern Med 22:495-500. 2011
    ....
  72. doi request reprint Early diagnosis of acute myocardial infarction in the elderly using more sensitive cardiac troponin assays
    Miriam Reiter
    Department of Internal Medicine, University Hospital, Petersgraben 4, CH 4031 Basel, Switzerland
    Eur Heart J 32:1379-89. 2011
    ..To examine the diagnostic accuracy of sensitive cardiac troponin (cTn) assays in elderly patients, since elevated levels with sensitive cTn assays were reported in 20% of elderly patients without acute myocardial infarction (AMI)...
  73. ncbi request reprint Early diagnosis of myocardial infarction with sensitive cardiac troponin assays
    Tobias Reichlin
    Department of Internal Medicine, University Hospital, Basel, Switzerland
    N Engl J Med 361:858-67. 2009
    ..The rapid and reliable diagnosis of acute myocardial infarction is a major unmet clinical need...
  74. ncbi request reprint Quantifying cardiac hemodynamic stress and cardiomyocyte damage in ischemic and nonischemic acute heart failure
    Beatrice Drexler
    Department of Internal Medicine, University Hospital Basel, Basel, Switzerland
    Circ Heart Fail 5:17-24. 2012
    ..The early and noninvasive differentiation of ischemic and nonischemic acute heart failure (AHF) in the emergency department (ED) is an unmet clinical need...
  75. pmc Direct comparison of serial B-type natriuretic peptide and NT-proBNP levels for prediction of short- and long-term outcome in acute decompensated heart failure
    Markus Noveanu
    Department of Internal Medicine, University Hospital Basel, Petersgraben 4, 4053 Basel, Switzerland
    Crit Care 15:R1. 2011
    ..Monitoring treatment efficacy and assessing outcome by serial measurements of natriuretic peptides in acute decompensated heart failure (ADHF) patients may help to improve outcome...
  76. doi request reprint Long-term benefit-risk balance of drug-eluting vs. bare-metal stents in daily practice: does stent diameter matter? Three-year follow-up of BASKET
    Matthias Pfisterer
    Department of Cardiology, University Hospital Basel, Petersgraben, Basel, Switzerland
    Eur Heart J 30:16-24. 2009
    ..To assess the long-term benefit-risk ratio of drug-eluting (DES) vs. bare-metal stents (BMS) relative to stent size...
  77. doi request reprint Endogenous stress response in Tako-Tsubo cardiomyopathy and acute myocardial infarction
    Julia Meissner
    Department of Internal Medicine, University Hospital Basel, Basel, Switzerland
    Eur J Clin Invest 41:964-70. 2011
    ....
  78. pmc Endothelin-1 precursor peptides correlate with severity of disease and outcome in patients with community acquired pneumonia
    Philipp Schuetz
    Department of Internal Medicine, University Hospital Basel, Switzerland
    BMC Infect Dis 8:22. 2008
    ..The objective of this study was to assess the diagnostic and prognostic value of proET-1 in a prospective cohort of mainly septic patients with community-acquired pneumonia...
  79. doi request reprint Effect and clinical prediction of worsening renal function in acute decompensated heart failure
    Tobias Breidthardt
    Department of Internal Medicine, University Hospital, Basel, Switzerland
    Am J Cardiol 107:730-5. 2011
    ..However, the clinical parameters failed to adequately predict its occurrence, making a tailored therapy approach impossible...
  80. pmc Effect of oral β-blocker on short and long-term mortality in patients with acute respiratory failure: results from the BASEL-II-ICU study
    Markus Noveanu
    Department of Internal Medicine, University Hospital Basel, Petersgraben 4, 4053 Basel, Switzerland
    Crit Care 14:R198. 2010
    ..The purpose of this analysis was to determine predictors of in-hospital and one-year mortality and assess the effects of oral beta-blockers in unselected ICU patients with ARF included in the BASEL-II-ICU study...
  81. doi request reprint Use of B-type natriuretic peptide in the management of hypoxaemic respiratory failure
    Markus Noveanu
    Department of Internal Medicine, University Hospital Basel, Petersgraben 4, CH 4031Basel, Switzerland
    Eur J Heart Fail 13:154-62. 2011
    ..The purpose of this study is to describe the prevalence of causative disorders of hypoxaemic respiratory failure in the ICU and to determine the impact of a BNP-guided diagnostic strategy...
  82. doi request reprint Percutaneous coronary intervention versus coronary artery bypass grafting as primary revascularization in patients with acute coronary syndrome
    Willibald Hochholzer
    Herz Zentrum, Bad Krozingen, Germany Department of Internal Medicine, University Hospital, Basel, Switzerland
    Am J Cardiol 102:173-9. 2008
    ....
  83. pmc Midregional pro-adrenomedullin in addition to b-type natriuretic peptides in the risk stratification of patients with acute dyspnea: an observational study
    Mihael Potocki
    Department of Internal Medicine, University Hospital, Petersgraben 4, 4031 Basel, Switzerland
    Crit Care 13:R122. 2009
    ....
  84. doi request reprint Cardiovascular biomarkers in the ICU
    Markus Noveanu
    Department of Internal Medicine, University Hospital Basel, Basel, Switzerland
    Curr Opin Crit Care 15:377-83. 2009
    ..This review focuses on recently published articles relating to the use of natriuretic peptides and cTn in critically ill patients...
  85. doi request reprint Use of changes in B-type natriuretic peptides to detect ischemia in selected patients
    Daniel Staub
    Department of Internal Medicine, University Hospital Basel, Switzerland
    Int J Cardiol 136:40-6. 2009
    ..The aim of this study was to either confirm or refute a previous investigation suggesting that myocardial ischemia can reliably be detected by exercise-induced changes in BNP or NT-proBNP levels in selected patients...
  86. doi request reprint Impact of body temperature on in-hospital and long-term mortality in patients with acute heart failure
    Theresia Klima
    Department of Internal Medicine, Institute of Social and Preventive Medicine, University Hospital Basel, Basel, Switzerland
    Swiss Med Wkly 138:299-304. 2008
    ..Body temperature (BT) was shown to have impact on outcome in several medical conditions. This study investigated the prognostic impact of BT in patients with acute heart failure (HF)...
  87. ncbi request reprint Hypertension is an independent risk factor for contrast nephropathy after percutaneous coronary intervention
    David Conen
    Department of Cardiology, University Hospital Basel, Switzerland
    Int J Cardiol 110:237-41. 2006
    ..We hypothesised that hypertension is an independent risk factor for the development of contrast nephropathy in patients undergoing percutaneous coronary intervention...
  88. doi request reprint Accuracy of chest radiographs in the emergency diagnosis of heart failure
    Ueli Studler
    Department of Radiology, University Hospital Basel, Petersgraben 4, 4031, Basel, Switzerland
    Eur Radiol 18:1644-52. 2008
    ..In our study, the combination of radiographic features provided valuable information and was of comparable accuracy as BNP-testing for the diagnosis of HF...
  89. ncbi request reprint Neurohormonal activation and left ventricular ejection fraction in patients with suspected myocardial ischemia
    Juerg Wermuth
    Department of Internal Medicine, Medical Division A, University Hospital, Petersgraben 4, CH 4031 Basel, Switzerland
    Int J Cardiol 120:248-53. 2007
    ..Unfortunately, there is very limited data regarding the association between BNP and LVEF...
  90. ncbi request reprint Use of N-terminal pro-B-type natriuretic peptide to detect myocardial ischemia
    Daniel Staub
    Department of Internal Medicine, University Hospital Basel, Basel, Switzerland
    Am J Med 118:1287. 2005
    ..To evaluate the utility of plasma N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels to detect myocardial ischemia...
  91. ncbi request reprint The impact of obesity on mortality in UA/non-ST-segment elevation myocardial infarction
    Heinz J Buettner
    Interventional Cardiology, Herz Zentrum, Südring 15, Bad Krozingen, Germany
    Eur Heart J 28:1694-701. 2007
    ..This study was designed to assess the impact of obesity on outcome after unstable angina/non-ST-segment elevation myocardial infarction (UA/NSTEMI) treated with early revascularization...
  92. doi request reprint Use of B-type natriuretic peptide outside of the emergency department
    Micha T Maeder
    Division of Cardiology, University Hospital Basel, Switzerland
    Int J Cardiol 127:5-16. 2008
    ..Despite active research in many additional fields, the use of BNP/NT-proBNP in other settings is not yet based on solid evidence and, therefore, seems not to be useful...
  93. ncbi request reprint Late clinical events after clopidogrel discontinuation may limit the benefit of drug-eluting stents: an observational study of drug-eluting versus bare-metal stents
    Matthias Pfisterer
    Department of Cardiology, University Hospital, Basel, Switzerland
    J Am Coll Cardiol 48:2584-91. 2006
    ..We sought to define the incidence of late clinical events and late stent thrombosis in patients treated with drug-eluting (DES) versus bare-metal stents (BMS) after the discontinuation of clopidogrel as well as their timing and outcome...
  94. ncbi request reprint Copeptin, C-reactive protein, and procalcitonin as prognostic biomarkers in acute exacerbation of COPD
    Daiana Stolz
    Clinic of Pneumology and Pulmonary Cell Research, University Hospital Basel, Petersgraben 4, CH 4031 Basel, Switzerland
    Chest 131:1058-67. 2007
    ....
  95. ncbi request reprint Clinical efficacy, tolerability, and safety of SAM486A, a novel polyamine biosynthesis inhibitor, in patients with relapsed or refractory non-Hodgkin's lymphoma: results from a phase II multicenter study
    Miklos Pless
    University Hospital of Basel, Switzerland
    Clin Cancer Res 10:1299-305. 2004
    ..This Phase IIa study reports the findings of SAM486A monotherapy in patients with refractory or relapsed non-Hodgkin's lymphoma (NHL)...
  96. ncbi request reprint Antibiotic treatment of exacerbations of COPD: a randomized, controlled trial comparing procalcitonin-guidance with standard therapy
    Daiana Stolz
    Clinics of Respiratory Medicine and Pulmonary Cell Research, University Hospital Basel, Basel, Switzerland
    Chest 131:9-19. 2007
    ..We evaluated the efficacy and safety of procalcitonin guidance compared to standard therapy with antibiotic prescriptions in patients experiencing exacerbations of COPD...
  97. doi request reprint [Development and implementation of a multidisciplinary nurse-led educational programme for inpatients with heart failure: the Basel-HF-Programme]
    Cornelia Bläuer
    Bereich Medizin, Universitatsspital Basel, Basel
    Pflege 24:29-41. 2011
    ..For the nurses the implementation of the programme was a new challenge of structured counselling in their normal "busy" routine because of this challenge the nurses needed continuing coaching...
  98. ncbi request reprint Plasma pro-adrenomedullin but not plasma pro-endothelin predicts survival in exacerbations of COPD
    Daiana Stolz
    Clinic of Pneumology, University Hospital Basel, Petersgraben 4, CH 4031 Basel, Switzerland
    Chest 134:263-72. 2008
    ..We investigated whether plasma pro-endothelin-1 (proET-1) and/or pro-adrenomedullin (proADM) on admission to the hospital for acute exacerbation predict survival in patients with COPD...
  99. ncbi request reprint Human factors affect the quality of cardiopulmonary resuscitation in simulated cardiac arrests
    Stephan C U Marsch
    Medical Intensive Care Unit, University of Basel, Kantonsspital, 4031 Basel, Switzerland
    Resuscitation 60:51-6. 2004
    ..The aim of the study was to determine whether and how human factors affect the quality of cardiopulmonary resuscitation...
  100. ncbi request reprint Gender-specific risk stratification with B-type natriuretic peptide levels in patients with acute dyspnea: insights from the B-type natriuretic peptide for acute shortness of breath evaluation study
    Michael Christ
    Department of Internal Medicine, Medical Division A, University Hospital, Basel, Switzerland
    J Am Coll Cardiol 48:1808-12. 2006
    ..We examined whether B-type natriuretic peptide (BNP) levels allow gender-specific risk stratification in patients with acute dyspnea...
  101. ncbi request reprint B-type natriuretic peptide levels predict event-free survival in patients with implantable cardioverter defibrillators
    Michael Christ
    Klinik fur Innere Medizin, Kardiologie, Germany
    Eur J Heart Fail 9:272-9. 2007
    ....