Xiu Fen Ming
Affiliation: University of Fribourg
Xiong Y, Yepuri G, Necetin S, Montani J, Ming X, Yang Z. Arginase-II Promotes Tumor Necrosis Factor-? Release From Pancreatic Acinar Cells Causing ?-Cell Apoptosis in Aging. Diabetes. 2017;66:1636-1649 pubmed publisher
Yu Y, Xiong Y, Montani J, Yang Z, Ming X. Arginase-II activates mTORC1 through myosin-1b in vascular cell senescence and apoptosis. Cell Death Dis. 2018;9:313 pubmed publisher
Ming X, Rajapakse A, Carvas J, Ruffieux J, Yang Z. Opposing and uncoupling effects of mTOR and S6K1 in the regulation of endothelial tissue factor expression. FEBS Lett. 2010;584:135-40 pubmed publisher
..The results reveal an opposing and uncoupling effect of mTOR and S6K1 in regulating TF expression. ..
Zhu C, Yu Y, Montani J, Ming X, Yang Z. Arginase-I enhances vascular endothelial inflammation and senescence through eNOS-uncoupling. BMC Res Notes. 2017;10:82 pubmed publisher
..Our study demonstrates that Arg-I promotes endothelial senescence and inflammatory responses through eNOS-uncoupling unrelated to activation of the S6K1 pathway. ..
Yu Y, Rajapakse A, Montani J, Yang Z, Ming X. p38 mitogen-activated protein kinase is involved in arginase-II-mediated eNOS-uncoupling in obesity. Cardiovasc Diabetol. 2014;13:113 pubmed publisher
..Taking together, we demonstrate here for the first time that Arg-II causes eNOS-uncoupling through activation of p38 mapk in HFD-induced obesity. ..
Ming X, Rajapakse A, Carvas J, Ruffieux J, Yang Z. Inhibition of S6K1 accounts partially for the anti-inflammatory effects of the arginase inhibitor L-norvaline. BMC Cardiovasc Disord. 2009;9:12 pubmed publisher
..The anti-inflammatory properties of L-norvaline are partially attributable to its ability to inhibit S6K1. ..