Philippe Millet

Summary

Affiliation: University Hospital
Country: Switzerland

Publications

  1. ncbi Evaluation of the reference tissue models for PET and SPECT benzodiazepine binding parameters
    Philippe Millet
    Division de Neuropsychiatrie, Unité de Neuroimagerie Psychiatrique, Hopitaux Universitaires de Geneve, Geneva, Switzerland
    Neuroimage 17:928-42. 2002
  2. ncbi Wavelet analysis of dynamic PET data: application to the parametric imaging of benzodiazepine receptor concentration
    P Millet
    Unité de Neuroimagerie Psychiatrique, Clinique de Psychiatrie, 2, chemin du Petit Bel Air, Chene Bourg, Geneva, CH 1225, Switzerland
    Neuroimage 11:458-72. 2000
  3. doi Innately low D2 receptor availability is associated with high novelty-seeking and enhanced behavioural sensitization to amphetamine
    Benjamin B Tournier
    Department of Psychiatry, University of Geneva, Chemin du Petit Bel Air 2, Geneva, Switzerland
    Int J Neuropsychopharmacol 16:1819-34. 2013
  4. doi Evidence of drug-drug interactions through uptake and efflux transport systems in rat hepatocytes: implications for cellular concentrations of competing drugs
    Youssef Daali
    Service de Pharmacologie et Toxicologie Clinique, Laboratoire de Physiopathologie Hépatique et Imagerie Moléculaire, Hopitaux Universitaires de Geneve, rue Gabrielle Perret Gentil, 4, 1205 Geneva, Switzerland
    Drug Metab Dispos 41:1548-56. 2013
  5. doi Concentrations of Gd-BOPTA in cholestatic fatty rat livers: role of transport functions through membrane proteins
    Catherine M Pastor
    Laboratoire de Physiopathologie Hépatique et Imagerie Moléculaire, Hopitaux Universitaires de Geneve, Geneva, Switzerland
    Contrast Media Mol Imaging 8:147-56. 2013
  6. ncbi SPECT quantification of benzodiazepine receptor concentration using a dual-ligand approach
    Philippe Millet
    Psychiatric Neuroimaging Unit, Division of Neuropsychiatry, Department of Psychiatry, University Hospitals of Geneva, Geneva, Switzerland
    J Nucl Med 47:783-92. 2006
  7. ncbi Chloramphenicol decreases brain glucose utilization and modifies the sleep-wake cycle architecture in rats
    Marcelle Moulin-Sallanon
    IFR19, Institut Federatif des Neurosciences de Lyon, Bron, France
    J Neurochem 93:1623-32. 2005
  8. ncbi In vivo measurement of glucose utilization in rats using a beta-microprobe: direct comparison with autoradiography
    Philippe Millet
    Unité de Neuroimagerie, Service de Neuropsychiatrie, Hopitaux Universitaires de Geneve, Chene Bourg, Switzerland
    J Cereb Blood Flow Metab 24:1015-24. 2004
  9. doi Neuroanatomical and neuropsychological features of euthymic patients with bipolar disorder
    Christophe Delaloye
    Division of Geriatric Psychiatry, University Hospitals of Geneva and Faculty of Medicine, Switzerland
    Am J Geriatr Psychiatry 17:1012-21. 2009
  10. doi In vivo quantification of 5-HT1A-[18F]MPPF interactions in rats using the YAP-(S)PET scanner and a beta-microprobe
    Philippe Millet
    Psychiatric Neuroimaging Unit, Division of Neuropsychiatry, Department of Psychiatry, University Hospital of Geneva, Switzerland
    Neuroimage 41:823-34. 2008

Collaborators

Detail Information

Publications13

  1. ncbi Evaluation of the reference tissue models for PET and SPECT benzodiazepine binding parameters
    Philippe Millet
    Division de Neuropsychiatrie, Unité de Neuroimagerie Psychiatrique, Hopitaux Universitaires de Geneve, Geneva, Switzerland
    Neuroimage 17:928-42. 2002
    ..It seems that the physiological values found in gray matter structures using these radioligands give acceptable BP values. We conclude that the reference tissue methods should be carefully evaluated for each radioligand...
  2. ncbi Wavelet analysis of dynamic PET data: application to the parametric imaging of benzodiazepine receptor concentration
    P Millet
    Unité de Neuroimagerie Psychiatrique, Clinique de Psychiatrie, 2, chemin du Petit Bel Air, Chene Bourg, Geneva, CH 1225, Switzerland
    Neuroimage 11:458-72. 2000
    ..The use of the wavelet-based filtering method can be extended far beyond the multi-injection protocol. It is likely to be also effective for other dynamic PET studies...
  3. doi Innately low D2 receptor availability is associated with high novelty-seeking and enhanced behavioural sensitization to amphetamine
    Benjamin B Tournier
    Department of Psychiatry, University of Geneva, Chemin du Petit Bel Air 2, Geneva, Switzerland
    Int J Neuropsychopharmacol 16:1819-34. 2013
    ..This suggests that D2R deficits in SN/VTA and striatum could both constitute neurochemical markers of an addiction-prone phenotype. ..
  4. doi Evidence of drug-drug interactions through uptake and efflux transport systems in rat hepatocytes: implications for cellular concentrations of competing drugs
    Youssef Daali
    Service de Pharmacologie et Toxicologie Clinique, Laboratoire de Physiopathologie Hépatique et Imagerie Moléculaire, Hopitaux Universitaires de Geneve, rue Gabrielle Perret Gentil, 4, 1205 Geneva, Switzerland
    Drug Metab Dispos 41:1548-56. 2013
    ..Moreover, drug interactions through transporters change greatly over time. ..
  5. doi Concentrations of Gd-BOPTA in cholestatic fatty rat livers: role of transport functions through membrane proteins
    Catherine M Pastor
    Laboratoire de Physiopathologie Hépatique et Imagerie Moléculaire, Hopitaux Universitaires de Geneve, Geneva, Switzerland
    Contrast Media Mol Imaging 8:147-56. 2013
    ..Understanding how ¹⁵³Gd-BOPTA accumulates in hepatocytes is then complex. However, such understanding is important to analyze liver imaging with hepatobiliary contrast agents in cholestatic fatty livers...
  6. ncbi SPECT quantification of benzodiazepine receptor concentration using a dual-ligand approach
    Philippe Millet
    Psychiatric Neuroimaging Unit, Division of Neuropsychiatry, Department of Psychiatry, University Hospitals of Geneva, Geneva, Switzerland
    J Nucl Med 47:783-92. 2006
    ..In this study, we applied a dual-ligand protocol using the unlabeled ligand flumazenil, which lacks pharmacologic effects, to quantify all binding parameters of the benzodiazepine receptor-(123)I-iomazenil interactions...
  7. ncbi Chloramphenicol decreases brain glucose utilization and modifies the sleep-wake cycle architecture in rats
    Marcelle Moulin-Sallanon
    IFR19, Institut Federatif des Neurosciences de Lyon, Bron, France
    J Neurochem 93:1623-32. 2005
    ..Spectral analysis of the electroencephalogram indicates that chloramphenicol induces long-lasting modifications of delta-band power during slow-wave sleep...
  8. ncbi In vivo measurement of glucose utilization in rats using a beta-microprobe: direct comparison with autoradiography
    Philippe Millet
    Unité de Neuroimagerie, Service de Neuropsychiatrie, Hopitaux Universitaires de Geneve, Chene Bourg, Switzerland
    J Cereb Blood Flow Metab 24:1015-24. 2004
    ..In addition, the betaP-derived input function was similar to that obtained by manual sampling. Our findings show that reliable rCMRglc values can be obtained using betaP...
  9. doi Neuroanatomical and neuropsychological features of euthymic patients with bipolar disorder
    Christophe Delaloye
    Division of Geriatric Psychiatry, University Hospitals of Geneva and Faculty of Medicine, Switzerland
    Am J Geriatr Psychiatry 17:1012-21. 2009
    ..To explore this issue, the authors performed a case-control study including detailed neuropsychological and magnetic resonance imaging analyses in 17 euthymic elderly patients with BD and 17 healthy individuals...
  10. doi In vivo quantification of 5-HT1A-[18F]MPPF interactions in rats using the YAP-(S)PET scanner and a beta-microprobe
    Philippe Millet
    Psychiatric Neuroimaging Unit, Division of Neuropsychiatry, Department of Psychiatry, University Hospital of Geneva, Switzerland
    Neuroimage 41:823-34. 2008
    ..895) and YAP-(S)PET (r=0.695). The YAP-(S)PET system underestimated the [18F]MPPF binding levels in brain due to limited resolution (i.e. partial volume), but led to similar conclusions...
  11. pmc Chronic Δ⁹-tetrahydrocannabinol exposure induces a sensitization of dopamine D₂/₃ receptors in the mesoaccumbens and nigrostriatal systems
    Nathalie Ginovart
    University Department of Psychiatry, University of Geneva, Geneva, Switzerland
    Neuropsychopharmacology 37:2355-67. 2012
    ..Such D₂/₃R neuroadaptations may contribute to the reinforcing and habit-forming properties of THC...
  12. doi How organic anions accumulate in hepatocytes lacking Mrp2: evidence in rat liver
    Philippe Millet
    Unite de Neurophysiologie et Neuroimagerie, Hopitaux Universitaires de Geneve, Geneva, Switzerland
    J Pharmacol Exp Ther 336:624-32. 2011
    ..Such information improves our understanding of liver imaging associated with the perfusion of hepatobiliary contrast agents, which was recently introduced in clinical practice...
  13. ncbi Resting state brain glucose metabolism is not reduced in normotensive healthy men during aging, after correction for brain atrophy
    Vicente Ibanez
    Brain Physiology and Metabolism Section, National Institute on Aging, National Institutes of Health, Bethesda, MD 20892, USA
    Brain Res Bull 63:147-54. 2004
    ..Thus, statistically significant age reductions in regional brain glucose metabolism, corrected for brain atrophy, are not detectable in healthy normotensive men scanned while in the resting state...