Research Topics
| Ch R MeierSummaryAffiliation: University of Basel Country: Switzerland Publications
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Detail Information
Publications
Angiotensin-converting enzyme inhibitors, calcium channel blockers, and breast cancerC R Meier
Boston Collaborative Drug Surveillance Program, Boston University School of Medicine, Lexington, Mass, USA
Arch Intern Med 160:349-53. 2000....
Association between body mass index and liver disorders: an epidemiological studyChristoph R Meier
Basel Pharmacoepidemiology Unit, Division of Clinical Pharmacology and Toxicology, Department of Internal Medicine, University Hospital Basel, Petersgraben 4, 4031 Basel, Switzerland
J Hepatol 37:741-7. 2002..Cross-sectional studies showed an association between obesity and liver disorders. Information on incidence rates from epidemiological studies is scarce...
Association between acetaminophen or nonsteroidal antiinflammatory drugs and risk of developing ovarian, breast, or colon cancerChristoph R Meier
Division of Clinical Pharmacology and Toxicology, University Hospital Basel, Switzerland
Pharmacotherapy 22:303-9. 2002..To explore the association between exposure to acetaminophen (paracetamol) or nonsteroidal antiinflammatory drugs (NSAIDs) and risk of developing ovarian, breast, or colon cancer...
Use of selective serotonin reuptake inhibitors and risk of developing first-time acute myocardial infarctionC R Meier
Basel Pharmacoepidemiology Unit, Division of Clinical Pharmacology, University Hospital, Basel, Switzerland
Br J Clin Pharmacol 52:179-84. 2001....
Population-based study on incidence, risk factors, clinical complications and drug utilisation associated with influenza in the United KingdomC R Meier
Department of Internal Medicine, University Hospital, Basel, Switzerland
Eur J Clin Microbiol Infect Dis 19:834-42. 2000..This analysis may lead to further analyses on the economic impact of influenza and the contribution of different population groups to that burden...
HMG-CoA reductase inhibitors and the risk of fracturesC R Meier
Basel Pharmacoepidemiology Unit, Division of Clinical Pharmacology, University Hospital of Basel, Petersgraben 4, CH 4031, Basel, Switzerland
JAMA 283:3205-10. 2000..It is unknown whether use of statins is associated with a decreased risk of fractures in humans...
Antibiotics in the prevention and treatment of coronary heart diseaseC R Meier
Basel Pharmacoepidemiology Unit, Division of Clinical Pharmacology, Dept of Internal Medicine, University Hospital, 4031 Basel, Switzerland
J Infect Dis 181:S558-62. 2000..This review of published studies briefly summarizes the currently available literature on the effects of antibiotics on the risk of developing coronary heart disease and myocardial infarction...
[Is it possible to do pharmaco-epidemiological research using electronic databanks in the Swiss health care system?]Ch R Meier
Basel Pharmacoepidemiology Unit, Abteilung Klinische Pharmakologie und Toxikologie Departement Innere Medizin Kantonsspital Basel 4031 Basel
Praxis (Bern 1994) 92:997-1000. 2003
Drug interactions and risk of acute bleeding leading to hospitalisation or death in patients with chronic atrial fibrillation treated with warfarinChristiane Gasse
Department of Internal MedicineVI, Clinical Pharmacology and Pharmacoepidemiology, University of Heidelberg, Germany
Thromb Haemost 94:537-43. 2005..warfarin alone was 4.5 (95% CI: 1.1-18.1). We conclude that concurrent use of potentially interacting drugs with warfarin is associated with a 3 to 4.5-fold increased risk of serious bleeding in long-term warfarin users...
Migraine and the risk of stroke, TIA, or death in the UK (CME)Claudia Becker
Basel Pharmacoepidemiology Unit, Division of Clinical Pharmacology and Toxicology, University Hospital Basel, Switzerland
Headache 47:1374-84. 2007..Previous observational studies have reported a higher risk of stroke in migraine patients. Objective.- We aimed to estimate the risk of stroke, transient ischemic attack (TIA), or death in migraineurs in the UK...
Use of statins and the risk of Parkinson's disease: a retrospective case-control study in the UKClaudia Becker
Basel Pharmacoepidemiology Unit, Division of Clinical Pharmacology and Toxicology, University Hospital Basel, Basel, Switzerland
Drug Saf 31:399-407. 2008..Paradoxically, however, statins may have potentially beneficial effects on neurodegenerative diseases due to their anti-inflammatory properties...
Use of thiazolidinediones and fracture riskChristian Meier
Division of Endocrinology, Diabetes, and Clinical Nutrition, University Hospital Basel, Hebelstrasse 2, CH 4031 Basel, Switzerland
Arch Intern Med 168:820-5. 2008..Thiazolidinediones may adversely affect the skeleton owing to decreased bone formation and accelerated bone loss...
Current use of selective serotonin reuptake inhibitors and risk of acute myocardial infarctionRaymond G Schlienger
Basel Pharmacoepidemiology Unit, Division of Clinical Pharmacology and Toxicology, University Hospital Basel, Basel, Switzerland
Drug Saf 27:1157-65. 2004..42 (95% CI 1.02, 1.97; p=0.04). CONCLUSION: The present analysis provides further evidence that the current use of SSRIs is associated with a slightly decreased risk for AMI...
Effect of rheumatoid arthritis or systemic lupus erythematosus on the risk of first-time acute myocardial infarctionLorenz M Fischer
Basel Pharmacoepidemiology Unit, Division of Clinical Pharmacology and Toxicology, University Hospital Basel, Basel, Switzerland
Am J Cardiol 93:198-200. 2004..23 to 1.76), and in subjects with both RA and diagnosed hyperlipidemia, the OR was 7.12 (95% CI 4.16 to 12.18). The risk associated with SLE was 2.67 (95% CI 1.34 to 5.34). These results underline that RA and SLE increase the risk of AMI...
Inhaled corticosteroids and the risk of fractures in children and adolescentsRaymond G Schlienger
Basel Pharmacoepidemiology Unit, Division of Clinical Pharmacology and Toxicology, University Hospital, Petersgraben 4, CH-4031 Basel, Switzerland
Pediatrics 114:469-73. 2004..21 (95% confidence interval: 0.99-1.49). CONCLUSIONS: Exposure to inhaled steroids does not materially increase the fracture risk in children or adolescents compared with nonexposed individuals...
Use of nonsteroidal anti-inflammatory drugs and the risk of first-time acute myocardial infarctionRaymond G Schlienger
Basel Pharmacoepidemiology Unit, Division of Clinical Pharmacology and Toxicology, University Hospital, Basel, Switzerland
Br J Clin Pharmacol 54:327-32. 2002..CONCLUSIONS: Our findings indicate that current NSAID exposure in patients free of diagnosed cardiovascular or metabolic conditions predisposing to cardiovascular diseases does not decrease the risk of AMI...
Validity of the general practice research databaseSusan S Jick
Boston Collaborative Drug Surveillance Program, Boston University School of Medicine, Lexington, Massachusetts 02421, USA
Pharmacotherapy 23:686-9. 2003..We reviewed evidence related to the validity of the GPRD. Specifically, with our extensive experience with this automated database, we evaluated the quality and completeness of the data that it contains...
Use of antihypertensives and the risk of Parkinson diseaseClaudia Becker
Basel Pharmacoepidemiology Unit, Division of Clinical Pharmacology and Toxicology, University Hospital Basel, Hebelstrasse 2, CH 4031 Basel, Switzerland
Neurology 70:1438-44. 2008..Recent studies related angiotensin converting enzyme (ACE) inhibitors and calcium channel blockers to possible neuroprotective effects. Little is known about neuroprotection of angiotensin II (AT II) antagonists or beta-blockers...
Risk factors for gastrointestinal bleeding: a hospital-based case-control studyPriska Vonbach
Hospital Pharmacy, Kantonsspital Winterthur University Children s Hospital Zurich, Switzerland
Swiss Med Wkly 137:705-10. 2007..We investigated risk factors for a first-time GI bleeding leading to hospital admission with a focus on drugs and drug-drug interactions (DDIs)...
Association between use of thiazolidinediones or other oral antidiabetics and psoriasis: A population based case-control studyYolanda B Brauchli
Basel Pharmacoepidemiology Unit, Division of Clinical Pharmacology and Toxicology, University Hospital Basel, Basel, Switzerland
J Am Acad Dermatol 58:421-9. 2008..Small clinical trials suggest that thiazolidinediones may exert a beneficial effect on skin lesions of patients with psoriasis. Little is known about other classes of antidiabetic drugs and the psoriasis risk...
The risk of newly diagnosed asthma in migraineurs with or without previous triptan prescriptionsClaudia Becker
Basel Pharmacoepidemiology Unit, Division of Clinical Pharmacology and Toxicology, University Hospital Basel, Basel, Switzerland
Headache 48:606-10. 2008..Previous observational studies reported an increased prevalence of asthma in migraine patients. Whether triptans affect the asthma risk has not yet been explored in an epidemiological study...
Use of beta-blockers and risk of fracturesRaymond G Schlienger
Basel Pharmacoepidemiology Unit, Division of Clinical Pharmacology and Toxicology, University Hospital, Basel, Switzerland
JAMA 292:1326-32. 2004..Many elderly patients with hypertension who are at risk of developing osteoporosis may potentially benefit from combined therapy with beta-blockers and thiazides...
Benzodiazepine prescribing to the Swiss adult population: results from a national survey of community pharmaciesSylvie Petitjean
Division of Substance Use Disorders, University Psychiatric Clinics Basel, Wilhelm Klein Strasse 27, CH 4025 Basel, Switzerland
Int Clin Psychopharmacol 22:292-8. 2007..The purpose of the study was to assess prevalence of benzodiazepine use in the Swiss adult population and to assess on benzodiazepine prescription patterns of physicians in domiciliary practice...
Statins and the risk of pneumonia: a population-based, nested case-control studyRaymond G Schlienger
Basel Pharmacoepidemiology Unit, Division of Clinical Pharmacology and Toxicology, University Hospital Basel, Basel, Switzerland
Pharmacotherapy 27:325-32. 2007..To determine if the use of statins affects pneumonia-related outpatient visits, hospitalizations with survival, and deaths...
Commentary: statins and fracture risk--unresolved questionsChristoph R Meier
Basel Pharmacoepidemiology Unit, Division of Clinical Pharmacology and Toxicology, University Hospital Basel, Hebelstrasse 2, 4031 Basel, Switzerland
Int J Epidemiol 35:1308-9. 2006
The risk of severe depression, psychosis or panic attacks with prophylactic antimalarialsChristoph R Meier
Basel Pharmacoepidemiology Unit, Division of Clinical Pharmacology and Toxicology, University Hospital Basel, Basel, Switzerland
Drug Saf 27:203-13. 2004....
Current use of nonsteroidal antiinflammatory drugs and the risk of acute myocardial infarctionLorenz M Fischer
Basel Pharmacoepidemiology Unit, Division of Clinical Pharmacology and Toxicology, University Hospital, Basel, Switzerland
Pharmacotherapy 25:503-10. 2005..We found no evidence for a reduced cardioprotective effect of aspirin with concomitant NSAID use...
Discontinuation of nonsteroidal anti-inflammatory drug therapy and risk of acute myocardial infarctionLorenz M Fischer
Basel Pharmacoepidemiology Unit, Division of Clinical Pharmacology and Toxicology, University Hospital Basel, Basel, Switzerland
Arch Intern Med 164:2472-6. 2004..07 [95% CI, 0.96-1.19] and 1.05 [95% CI, 0.99-1.12], respectively). CONCLUSION: Our findings suggest that the risk of AMI is increased during several weeks after the cessation of NSAID therapy...
Diabetes in patients with idiopathic Parkinson's diseaseClaudia Becker
Basel Pharmacoepidemiology Unit, Division of Clinical Pharmacology and Toxicology, University Hospital, Basel, Switzerland
Diabetes Care 31:1808-12. 2008..We aimed at comparing the diabetes prevalence between patients with or without Parkinson's disease and at exploring the risk of developing incident diabetes associated with Parkinson's disease...
