R A McKinney

Summary

Affiliation: University of Zurich
Country: Switzerland

Publications

  1. ncbi request reprint Miniature synaptic events maintain dendritic spines via AMPA receptor activation
    R A McKinney
    Brain Research Institute, University of Zurich, Switzerland
    Nat Neurosci 2:44-9. 1999
  2. ncbi request reprint Lesion-induced axonal sprouting and hyperexcitability in the hippocampus in vitro: implications for the genesis of posttraumatic epilepsy
    R A McKinney
    Brain Research Institute, University of Zurich, Switzerland
    Nat Med 3:990-6. 1997
  3. pmc Selective glutamate receptor antagonists can induce or prevent axonal sprouting in rat hippocampal slice cultures
    R A McKinney
    Brain Research Institute, University of Zurich, Winterthurerstrasse 190, CH 8057 Zurich, Switzerland
    Proc Natl Acad Sci U S A 96:11631-6. 1999
  4. ncbi request reprint NMDA receptor activation limits the number of synaptic connections during hippocampal development
    A Luthi
    Brain Research Institute, University of Zurich, Winterthurerstrasse 190, CH 8057, Zurich, Switzerland
    Nat Neurosci 4:1102-7. 2001
  5. pmc Somatic voltage-gated potassium currents of rat hippocampal pyramidal cells in organotypic slice cultures
    J L Bossu
    Brain Research Institute, University of Zurich, Switzerland
    J Physiol 495:367-81. 1996
  6. ncbi request reprint Organotypic cultures of the rat anterior pituitary: morphology, physiology and cell-to-cell communication
    N C Guerineau
    Brain Research Institute, University of Zurich, Switzerland
    J Neurosci Methods 73:169-76. 1997
  7. pmc Differential control of GABA release at synapses from distinct interneurons in rat hippocampus
    J C Poncer
    Brain Research Institute, University of Zurich Winterthurerstrasse 190, CH 8057 Zurich, Switzerland
    J Physiol 528:123-30. 2000
  8. ncbi request reprint Mechanisms underlying the neuropathological consequences of epileptic activity in the rat hippocampus in vitro
    S M Thompson
    Brain Research Institute, University of Zurich, Switzerland
    J Comp Neurol 372:515-28. 1996
  9. ncbi request reprint Local changes in vascular architecture following partial spinal cord lesion in the rat
    E L Imperato-Kalmar
    Brain Research Institute, University of Zurich, Switzerland
    Exp Neurol 145:322-8. 1997
  10. pmc AMPA-receptor activation regulates the diffusion of a membrane marker in parallel with dendritic spine motility in the mouse hippocampus
    D A Richards
    Brain Research Institute, University of Zurich, Zurich, Switzerland
    J Physiol 558:503-12. 2004

Detail Information

Publications10

  1. ncbi request reprint Miniature synaptic events maintain dendritic spines via AMPA receptor activation
    R A McKinney
    Brain Research Institute, University of Zurich, Switzerland
    Nat Neurosci 2:44-9. 1999
    ..Synaptically released glutamate thus exerts a trophic effect on spines by acting at AMPA receptors. We conclude that AMPA receptor activation by spontaneous vesicular glutamate release is sufficient to maintain dendritic spines...
  2. ncbi request reprint Lesion-induced axonal sprouting and hyperexcitability in the hippocampus in vitro: implications for the genesis of posttraumatic epilepsy
    R A McKinney
    Brain Research Institute, University of Zurich, Switzerland
    Nat Med 3:990-6. 1997
    ..We thus demonstrate that recurrent axon collaterals are newly sprouted by pyramidal cells as a consequence of axonal injury and suggest that this underlies the development of posttraumatic epilepsy...
  3. pmc Selective glutamate receptor antagonists can induce or prevent axonal sprouting in rat hippocampal slice cultures
    R A McKinney
    Brain Research Institute, University of Zurich, Winterthurerstrasse 190, CH 8057 Zurich, Switzerland
    Proc Natl Acad Sci U S A 96:11631-6. 1999
    ..Activation of non-NMDA receptors appears necessary for these processes to occur, whereas activation of NMDA receptors suppresses growth-associated protein -43 expression and axonal outgrowth...
  4. ncbi request reprint NMDA receptor activation limits the number of synaptic connections during hippocampal development
    A Luthi
    Brain Research Institute, University of Zurich, Winterthurerstrasse 190, CH 8057, Zurich, Switzerland
    Nat Neurosci 4:1102-7. 2001
    ..Thus, the development of excitatory circuitry in the hippocampus is determined by two opposing processes: NMDA receptor-independent synapse formation and NMDA receptor-dependent attenuation of synaptogenesis...
  5. pmc Somatic voltage-gated potassium currents of rat hippocampal pyramidal cells in organotypic slice cultures
    J L Bossu
    Brain Research Institute, University of Zurich, Switzerland
    J Physiol 495:367-81. 1996
    ..Intracellular recordings in CA3 pyramidal cells showed that IK(AT) plays an important role in regulating the duration of the action potential...
  6. ncbi request reprint Organotypic cultures of the rat anterior pituitary: morphology, physiology and cell-to-cell communication
    N C Guerineau
    Brain Research Institute, University of Zurich, Switzerland
    J Neurosci Methods 73:169-76. 1997
    ..This neuroendocrine preparation is suitable for studying the mechanisms regulating cell-to-cell communication under conditions resembling the in vivo tissue organization...
  7. pmc Differential control of GABA release at synapses from distinct interneurons in rat hippocampus
    J C Poncer
    Brain Research Institute, University of Zurich Winterthurerstrasse 190, CH 8057 Zurich, Switzerland
    J Physiol 528:123-30. 2000
    ..However, CGP52432 did reduce PPD of extracellularly evoked IPSPs. 6. Our results show that two groups of inhibitory synapses impinging onto CA3 pyramidal cells can be distinguished according to their dynamic and modulatory properties...
  8. ncbi request reprint Mechanisms underlying the neuropathological consequences of epileptic activity in the rat hippocampus in vitro
    S M Thompson
    Brain Research Institute, University of Zurich, Switzerland
    J Comp Neurol 372:515-28. 1996
    ..We conclude that NMDA receptor activation is not solely responsible for the neuronal pathology resulting as a consequence of epileptiform discharge...
  9. ncbi request reprint Local changes in vascular architecture following partial spinal cord lesion in the rat
    E L Imperato-Kalmar
    Brain Research Institute, University of Zurich, Switzerland
    Exp Neurol 145:322-8. 1997
    ..These results show significant initial attempts at repair of the vasculature which do not, however, lead to the restoration of a compact tissue and cannot prevent the subsequent formation of caverns...
  10. pmc AMPA-receptor activation regulates the diffusion of a membrane marker in parallel with dendritic spine motility in the mouse hippocampus
    D A Richards
    Brain Research Institute, University of Zurich, Zurich, Switzerland
    J Physiol 558:503-12. 2004
    ....