T Matthes

Summary

Affiliation: University Hospital
Country: Switzerland

Publications

  1. ncbi [Sideroblastic anemias]
    T Matthes
    Hämatologie, Departement Innere Medizin, Universitätsspital Genf
    Ther Umsch 63:25-33. 2006
  2. ncbi Increased apoptosis in acquired sideroblastic anaemia
    T W Matthes
    Division of Haematology, Geneva University Hospital, Geneva, Switzerland
    Br J Haematol 111:843-52. 2000
  3. ncbi Severe hemochromatosis in a Portuguese family associated with a new mutation in the 5'-UTR of the HAMP gene
    Thomas Matthes
    Division of Hematology, University Hospital, Geneva, Switzerland
    Blood 104:2181-3. 2004
  4. pmc Using digital RNA counting and flow cytometry to compare mRNA with protein expression in acute leukemias
    Paula Fernandez
    Kantonsspital Aarau, Aarau, Switzerland
    PLoS ONE 7:e49010. 2012
  5. ncbi Different pathophysiological mechanisms of intramitochondrial iron accumulation in acquired and congenital sideroblastic anemia caused by mitochondrial DNA deletion
    Thomas Matthes
    Department of Internal Medicine, Unit of Clinical Hematology, University Hospital, Geneva, Switzerland
    Eur J Haematol 77:169-74. 2006
  6. ncbi Cytomegalovirus colitis--a severe complication after standard chemotherapy
    Thomas Matthes
    Division of Haematology, University Hospital Geneva, Geneva, Switzerland
    Acta Oncol 41:704-6. 2002
  7. ncbi Acquired and transient RBC CD55 deficiency (Inab phenotype) and anti-IFC
    Thomas Matthes
    Division of Hematology, Geneva University Hospital, Geneva, Switzerland
    Transfusion 42:1448-57. 2002
  8. ncbi [Acute leukemias]
    J R Passweg
    Service d Hematologie, HUG, Geneve
    Rev Med Suisse 4:1272-4, 1276-8. 2008
  9. ncbi [Effect of administration of recombinant human erythropoietin in acute normovolemic hemodilution on transfusion needs during total hip prosthesis implantation]
    P Beris
    Division d Hématologie, Hopital Cantonal Universitaire de Geneve
    Schweiz Med Wochenschr 128:1582-6. 1998
  10. ncbi Molecular mechanism of hepcidin deficiency in a patient with juvenile hemochromatosis
    Alexandra Rideau
    Haematologica 92:127-8. 2007

Collaborators

Detail Information

Publications11

  1. ncbi [Sideroblastic anemias]
    T Matthes
    Hämatologie, Departement Innere Medizin, Universitätsspital Genf
    Ther Umsch 63:25-33. 2006
    ..The molecular defects of a few hereditary forms have already been elucidated, but the genes involved in the acquired forms are still largely unknown...
  2. ncbi Increased apoptosis in acquired sideroblastic anaemia
    T W Matthes
    Division of Haematology, Geneva University Hospital, Geneva, Switzerland
    Br J Haematol 111:843-52. 2000
    ..g. Fe accumulation, secondary to mitochondrial or nuclear DNA mutations) or is secondary to an extracellular stimulus [e.g. tumour necrosis factor (TNF), Fas ligand (FasL)] remains to be determined...
  3. ncbi Severe hemochromatosis in a Portuguese family associated with a new mutation in the 5'-UTR of the HAMP gene
    Thomas Matthes
    Division of Hematology, University Hospital, Geneva, Switzerland
    Blood 104:2181-3. 2004
    ..The decrease of hepcidin production would thus lead to increased iron absorption, resulting in iron deposition in parenchymal tissues. Phlebotomy therapy of the 2 patients resulted in impressive clinical improvement...
  4. pmc Using digital RNA counting and flow cytometry to compare mRNA with protein expression in acute leukemias
    Paula Fernandez
    Kantonsspital Aarau, Aarau, Switzerland
    PLoS ONE 7:e49010. 2012
    ..We evaluated this technique in a Swiss multi-center study on eighty-six samples from acute leukemia patients...
  5. ncbi Different pathophysiological mechanisms of intramitochondrial iron accumulation in acquired and congenital sideroblastic anemia caused by mitochondrial DNA deletion
    Thomas Matthes
    Department of Internal Medicine, Unit of Clinical Hematology, University Hospital, Geneva, Switzerland
    Eur J Haematol 77:169-74. 2006
    ..g. nuclear DNA mutations, have to be proposed to be involved in the acquired forms of SA...
  6. ncbi Cytomegalovirus colitis--a severe complication after standard chemotherapy
    Thomas Matthes
    Division of Haematology, University Hospital Geneva, Geneva, Switzerland
    Acta Oncol 41:704-6. 2002
    ..Significant immunosuppression leading to severe colitis by CMV infection or reactivation can occur after standard chemotherapy...
  7. ncbi Acquired and transient RBC CD55 deficiency (Inab phenotype) and anti-IFC
    Thomas Matthes
    Division of Hematology, Geneva University Hospital, Geneva, Switzerland
    Transfusion 42:1448-57. 2002
    ..This report describes the first example of a patient with an acquired and transient form of the Inab phenotype...
  8. ncbi [Acute leukemias]
    J R Passweg
    Service d Hematologie, HUG, Geneve
    Rev Med Suisse 4:1272-4, 1276-8. 2008
  9. ncbi [Effect of administration of recombinant human erythropoietin in acute normovolemic hemodilution on transfusion needs during total hip prosthesis implantation]
    P Beris
    Division d Hématologie, Hopital Cantonal Universitaire de Geneve
    Schweiz Med Wochenschr 128:1582-6. 1998
    ..This protocol should be further tested in a prospective randomised study (rHuEpo versus placebo) in order to assess the real benefit of rHuEpo...
  10. ncbi Molecular mechanism of hepcidin deficiency in a patient with juvenile hemochromatosis
    Alexandra Rideau
    Haematologica 92:127-8. 2007
    ..By transient in vitro transfection studies, we provide evidence that the additional ATG is functional and prevents normal hepcidin production by inducing an aberrant translation initiation of the pre-hepcidin mRNA...
  11. ncbi Asp1424Asn MYH9 mutation results in an unstable protein responsible for the phenotypes in May-Hegglin anomaly/Fechtner syndrome
    Samuel Deutsch
    University of Geneva, Switzerland
    Blood 102:529-34. 2003
    ..We hypothesize that haploinsufficiency of the MYH9 results in a failure to properly reorganize the cytoskeleton in megakaryocytes as required for efficient platelet production...