Affiliation: University of Lausanne
- A general multivariate extension of Fisher's geometrical model and the distribution of mutation fitness effects across speciesGuillaume Martin
Centre d Ecologie Fonctionnelle et Evolutive, Centre National de la Recherche Scientifique, UMR 5175, 1919 Route de Mende, 34 293 Montpellier, France
Evolution 60:893-907. 2006..More generally, the model seems to qualitatively capture and possibly explain the variation of f(s) from lower to higher organisms, which opens a large array of potential applications in evolutionary genetics...
- The fitness effect of mutations across environments: a survey in light of fitness landscape modelsGuillaume Martin
Centre d Ecologie Fonctionnelle et Evolutive, CNRS UMR 5175, 1919 Rte de Mende, 34 293 Montpellier, France
Evolution 60:2413-27. 2006..They also suggest that mutation parameter estimates may be strongly biased when measured in stressful environments...
- Distributions of epistasis in microbes fit predictions from a fitness landscape modelGuillaume Martin
Centre d écologie fonctionnelle et évolutive Centre National de la Recherche Scientifique UMR 5175, 1919 Route de Mende, 34293 Montpellier, France
Nat Genet 39:555-60. 2007..This model may offer a simple and widely applicable alternative to complex metabolic network models, in particular for making evolutionary predictions...
- Fitness landscapes: an alternative theory for the dominance of mutationFederico Manna
Centre d Ecologie Fonctionnelle et Evolutive, 34293 Montpellier, France
Genetics 189:923-37. 2011..Because dominance is a central parameter for evolutionary theory, and because these predictions are quantitative, they set the stage for a wide range of applications and further empirical tests...
- The distribution of beneficial and fixed mutation fitness effects close to an optimumGuillaume Martin
Centre d Ecologie Fonctionnelle et Evolutive, UMR CNRS 5175, 34295 Montpellier, France
Genetics 179:907-16. 2008..We show by simulations that these conclusions are fairly robust to a lower adaptation of the wild type and discuss the relevance of our findings in the context of adaptation theories and experimental evolution...
- Selection for recombination in structured populationsGuillaume Martin
Zoology Department, University of British Columbia, Vancouver, V6T 1Z4 British Columbia, Canada
Genetics 172:593-609. 2006..Overall, our results show that the stochastic theories of the evolution of sex apply to a much broader range of conditions than previously expected...
- Under neutrality, Q(ST) < or = F(ST) when there is dominance in an island modelJerome Goudet
Genetics 176:1371-4. 2007