Jacob G Malone

Summary

Affiliation: University of Basel
Country: Switzerland

Publications

  1. pmc YfiBNR mediates cyclic di-GMP dependent small colony variant formation and persistence in Pseudomonas aeruginosa
    Jacob G Malone
    Biozentrum, University of Basel, Basel, Switzerland
    PLoS Pathog 6:e1000804. 2010
  2. pmc Genomic and genetic analyses of diversity and plant interactions of Pseudomonas fluorescens
    Mark W Silby
    Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Centre for Adaptation Genetics and Drug Resistance, Boston, MA 02111, USA
    Genome Biol 10:R51. 2009
  3. pmc The YfiBNR signal transduction mechanism reveals novel targets for the evolution of persistent Pseudomonas aeruginosa in cystic fibrosis airways
    Jacob G Malone
    Biozentrum of the University of Basel, Basel, Switzerland
    PLoS Pathog 8:e1002760. 2012

Collaborators

  • Guy R Cornelis
  • Susanne Haussler
  • Andreas Dötsch
  • Christian Spangler
  • Mark W Silby
  • Ana M Cerdeño-Tárraga
  • Elton Stephens
  • Scott A C Godfrey
  • Christopher G Knight
  • Christopher M Thomas
  • Gregory L Challis
  • Rob Squares
  • Elizabeth Saunders
  • Lee Murphy
  • Stephen D Bentley
  • Simon Harris
  • Christina D Moon
  • Stefanie M Gehrig
  • Zena Robinson
  • Konstantinos Mavromatis
  • Stuart B Levy
  • Xue Xian Zhang
  • Julian Parkhill
  • Gail M Preston
  • Joanne Hothersall
  • Alice M Yaxley
  • Georgios S Vernikos
  • Kathy Seeger
  • Andrew J Spiers
  • Thomas S Brettin
  • Robert W Jackson
  • Stephen R Giddens
  • Paul B Rainey
  • Simon Rutter
  • Nicholas R Thomson
  • Michael A Quail
  • David Harris

Detail Information

Publications3

  1. pmc YfiBNR mediates cyclic di-GMP dependent small colony variant formation and persistence in Pseudomonas aeruginosa
    Jacob G Malone
    Biozentrum, University of Basel, Basel, Switzerland
    PLoS Pathog 6:e1000804. 2010
    ..This study establishes YfiBNR as an important player in P. aeruginosa persistence, and implicates a central role for c-di-GMP, and by extension the SCV phenotype in chronic infections...
  2. pmc Genomic and genetic analyses of diversity and plant interactions of Pseudomonas fluorescens
    Mark W Silby
    Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Centre for Adaptation Genetics and Drug Resistance, Boston, MA 02111, USA
    Genome Biol 10:R51. 2009
    ..A functional genomic in vivo expression technology (IVET) screen provided insight into genes used by P. fluorescens in its natural environment and an improved understanding of the ecological significance of diversity within this species...
  3. pmc The YfiBNR signal transduction mechanism reveals novel targets for the evolution of persistent Pseudomonas aeruginosa in cystic fibrosis airways
    Jacob G Malone
    Biozentrum of the University of Basel, Basel, Switzerland
    PLoS Pathog 8:e1002760. 2012
    ..aeruginosa during chronic lung infections. These experiments uncover an important new principle of in vivo persistence, and identify the c-di-GMP network as a valid target for novel anti-infectives directed against chronic infections...