Sanjiv A Luther

Summary

Affiliation: University of Lausanne
Country: Switzerland

Publications

  1. ncbi Guiding blind T cells and dendritic cells: A closer look at fibroblastic reticular cells found within lymph node T zones
    Sanjiv A Luther
    Department of Biochemistry, University of Lausanne, 1066 Epalinges, Switzerland
    Immunol Lett 138:9-11. 2011
  2. ncbi CCL21 is sufficient to mediate DC migration, maturation and function in the absence of CCL19
    Mirjam R Britschgi
    Department of Biochemistry, University of Lausanne, Epalinges, Switzerland
    Eur J Immunol 40:1266-71. 2010
  3. ncbi Dynamic regulation of notch 1 and notch 2 surface expression during T cell development and activation revealed by novel monoclonal antibodies
    Emma Fiorini
    Ludwig Institute for Cancer Research Ltd, Lausanne Branch, 1066 Epalinges, Switzerland
    J Immunol 183:7212-22. 2009
  4. ncbi Association of T-zone reticular networks and conduits with ectopic lymphoid tissues in mice and humans
    Alexander Link
    Department of Biochemistry, University of Lausanne, Epalinges, Switzerland
    Am J Pathol 178:1662-75. 2011
  5. ncbi Novel function for interleukin-7 in dendritic cell development
    Tobias K Vogt
    Department of Biochemistry, University of Lausanne, Epalinges, Switzerland
    Blood 113:3961-8. 2009
  6. ncbi Dynamic modulation of CCR7 expression and function on naive T lymphocytes in vivo
    Mirjam R Britschgi
    Department of Biochemistry, University of Lausanne, Epalinges, Switzerland
    J Immunol 181:7681-8. 2008
  7. ncbi Fibroblastic reticular cells in lymph nodes regulate the homeostasis of naive T cells
    Alexander Link
    Department of Biochemistry, University of Lausanne, 1066 Epalinges, Switzerland
    Nat Immunol 8:1255-65. 2007
  8. ncbi Fibroblastic reticular cells from lymph nodes attenuate T cell expansion by producing nitric oxide
    Stefanie Siegert
    Department of Biochemistry, University of Lausanne, Epalinges, Switzerland
    PLoS ONE 6:e27618. 2011
  9. ncbi Recirculating CD4 memory T cells mount rapid secondary responses without major contributions from follicular CD4 effectors and B cells
    Sanjiv A Luther
    Department of Biochemistry, University of Lausanne, Epalinges, Switzerland
    Eur J Immunol 37:1476-84. 2007
  10. ncbi Cutting edge: thymic crosstalk regulates delta-like 4 expression on cortical epithelial cells
    Emma Fiorini
    Ludwig Institute for Cancer Research, Lausanne Branch, University of Lausanne, Epalinges, Switzerland
    J Immunol 181:8199-203. 2008

Collaborators

Detail Information

Publications13

  1. ncbi Guiding blind T cells and dendritic cells: A closer look at fibroblastic reticular cells found within lymph node T zones
    Sanjiv A Luther
    Department of Biochemistry, University of Lausanne, 1066 Epalinges, Switzerland
    Immunol Lett 138:9-11. 2011
    ..This review is focused on the recent progress made in our understanding of the fibroblastic reticular stromal cells that form the 'niches' within the T zone...
  2. ncbi CCL21 is sufficient to mediate DC migration, maturation and function in the absence of CCL19
    Mirjam R Britschgi
    Department of Biochemistry, University of Lausanne, Epalinges, Switzerland
    Eur J Immunol 40:1266-71. 2010
    ..Our findings suggest that CCL21 is the critical CCR7 ligand regulating DC homeostasis and function in vivo with CCL19 being redundant for these processes...
  3. ncbi Dynamic regulation of notch 1 and notch 2 surface expression during T cell development and activation revealed by novel monoclonal antibodies
    Emma Fiorini
    Ludwig Institute for Cancer Research Ltd, Lausanne Branch, 1066 Epalinges, Switzerland
    J Immunol 183:7212-22. 2009
    ..Furthermore they provide an important resource for future analysis of Notch receptors in various tissues including the hematopoietic system...
  4. ncbi Association of T-zone reticular networks and conduits with ectopic lymphoid tissues in mice and humans
    Alexander Link
    Department of Biochemistry, University of Lausanne, Epalinges, Switzerland
    Am J Pathol 178:1662-75. 2011
    ..In conclusion, TRCs and conduits are hallmarks of secondary lymphoid organs and of well-developed TLTs, in both mice and humans, and are likely to act as important scaffold and organizer cells of the T-cell-rich zone...
  5. ncbi Novel function for interleukin-7 in dendritic cell development
    Tobias K Vogt
    Department of Biochemistry, University of Lausanne, Epalinges, Switzerland
    Blood 113:3961-8. 2009
    ....
  6. ncbi Dynamic modulation of CCR7 expression and function on naive T lymphocytes in vivo
    Mirjam R Britschgi
    Department of Biochemistry, University of Lausanne, Epalinges, Switzerland
    J Immunol 181:7681-8. 2008
    ..We propose that these two states of CCR7 are important to allow the various functions CCR7 plays in T cell recirculation...
  7. ncbi Fibroblastic reticular cells in lymph nodes regulate the homeostasis of naive T cells
    Alexander Link
    Department of Biochemistry, University of Lausanne, 1066 Epalinges, Switzerland
    Nat Immunol 8:1255-65. 2007
    ..Our data suggest that lymph nodes and T zone fibroblastic reticular cells have a key function in naive CD4(+) and CD8(+) T cell homeostasis by providing a limited reservoir of survival factors...
  8. ncbi Fibroblastic reticular cells from lymph nodes attenuate T cell expansion by producing nitric oxide
    Stefanie Siegert
    Department of Biochemistry, University of Lausanne, Epalinges, Switzerland
    PLoS ONE 6:e27618. 2011
    ..Our findings highlight that in addition to their established positive roles in T cell responses FRC and DC cooperate in a negative feedback loop to attenuate T cell expansion during acute inflammation...
  9. ncbi Recirculating CD4 memory T cells mount rapid secondary responses without major contributions from follicular CD4 effectors and B cells
    Sanjiv A Luther
    Department of Biochemistry, University of Lausanne, Epalinges, Switzerland
    Eur J Immunol 37:1476-84. 2007
    ..Accelerated memory CD4 T cell responses were also seen in B cell-deficient mice...
  10. ncbi Cutting edge: thymic crosstalk regulates delta-like 4 expression on cortical epithelial cells
    Emma Fiorini
    Ludwig Institute for Cancer Research, Lausanne Branch, University of Lausanne, Epalinges, Switzerland
    J Immunol 181:8199-203. 2008
    ..Collectively, our data support a model where thymic crosstalk quantitatively regulates the rate of Notch1-dependent thymopoiesis by controlling DL4 expression levels on cTEC...
  11. ncbi Expression and function of interleukin-7 in secondary and tertiary lymphoid organs
    Hsin Ying Huang
    Department of Biochemistry, University of Lausanne, Chemin des Boveresses 155, Epalinges, Switzerland
    Semin Immunol 24:175-89. 2012
    ..Finally, we will review the role of IL-7 in development of SLO and tertiary lymphoid tissues that frequently are associated with sites of chronic inflammation...
  12. ncbi Positive and negative regulation of T cell responses by fibroblastic reticular cells within paracortical regions of lymph nodes
    Stefanie Siegert
    Department of Biochemistry, University of Lausanne Epalinges, Switzerland
    Front Immunol 3:285. 2012
    ..However, during an acute response, FRC limit excessive expansion and inflammatory activity of antigen-specific T cells. This negative feedback loop may help to maintain tissue integrity and function during rapid organ growth...
  13. ncbi Preferential infection of immature dendritic cells and B cells by mouse mammary tumor virus
    Sonia Vacheron
    Ludwig Institute for Cancer Research, Lausanne Branch, University of Lausanne, Epalinges, Switzerland
    J Immunol 168:3470-6. 2002
    ..These results highlight the importance of professional APC and efficient T cell priming for the establishment of a persistent infection by mouse mammary tumor virus...