K Lippuner

Summary

Affiliation: University Hospital
Country: Switzerland

Publications

  1. ncbi request reprint How well do radiographic absorptiometry and quantitative ultrasound predict osteoporosis at spine or hip? A cost-effectiveness analysis
    K Lippuner
    Osteoporosis Unit, University Hospital of Berne, Switzerland
    J Clin Densitom 3:241-9. 2000
  2. ncbi request reprint Epidemiology and direct medical costs of osteoporotic fractures in men and women in Switzerland
    Kurt Lippuner
    Osteoporosis Policlinic, University Hospital of Berne, Switzerland
    Osteoporos Int 16:S8-S17. 2005
  3. doi request reprint [Osteoporosis - whom to treat? The importance of FRAX® in Switzerland]
    Kurt Lippuner
    Universitätspoliklinik für Osteoporose, Inselspital, Bern
    Ther Umsch 69:207-13. 2012
  4. pmc Recommendations for raloxifene use in daily clinical practice in the Swiss setting
    Kurt Lippuner
    Universitätspoliklinik für Osteoporose, Inselspital Bern, 3010 Bern, Switzerland
    Eur Spine J 21:2407-17. 2012
  5. doi request reprint Cost-effective intervention thresholds against osteoporotic fractures based on FRAX® in Switzerland
    K Lippuner
    Osteoporosis Policlinic, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland
    Osteoporos Int 23:2579-89. 2012
  6. doi request reprint The future of osteoporosis treatment - a research update
    Kurt Lippuner
    Osteoporosis Policlinic, Inselspital, Bern University Hospital and University of Bern, Switzerland
    Swiss Med Wkly 142:w13624. 2012
  7. doi request reprint [Epidemiology and burden of osteoporosis in Switzerland]
    Kurt Lippuner
    Universitätspoliklinik für Osteoporose, Inselspital, Bern
    Ther Umsch 69:137-44. 2012
  8. doi request reprint Comparative trends in hospitalizations for osteoporotic fractures and other frequent diseases between 2000 and 2008
    K Lippuner
    Osteoporosis Policlinic, Inselspital, Bern University Hospital and University of Bern, CH 3010 Bern, Switzerland
    Osteoporos Int 23:829-39. 2012
  9. ncbi request reprint Fracture hospitalizations between years 2000 and 2007 in Switzerland: a trend analysis
    K Lippuner
    Osteoporosis Policlinic, Inselspital, Bern University Hospital, University of Bern, 3010, Bern, Switzerland
    Osteoporos Int 22:2487-97. 2011
  10. ncbi request reprint [Epidemiology of osteoporotic fractures in Switzerland]
    K Lippuner
    Policlinique pour l ostéoporose, Hôpital de l lle de Berne, Hôpital universitaire et Université de Berne, Berne
    Rev Med Suisse 5:1304-8. 2009

Collaborators

Detail Information

Publications35

  1. ncbi request reprint How well do radiographic absorptiometry and quantitative ultrasound predict osteoporosis at spine or hip? A cost-effectiveness analysis
    K Lippuner
    Osteoporosis Unit, University Hospital of Berne, Switzerland
    J Clin Densitom 3:241-9. 2000
    ..CALC), 42% (SOS.PHAL), and 25% (SOS.TIB). In conclusion, RA, QUS.CALC, SOS.PHAL, and SOS.TIB may be useful to preselect postmenopausal women in whom axial DXA is indicated to confirm/exclude osteoporosis at spine or hip...
  2. ncbi request reprint Epidemiology and direct medical costs of osteoporotic fractures in men and women in Switzerland
    Kurt Lippuner
    Osteoporosis Policlinic, University Hospital of Berne, Switzerland
    Osteoporos Int 16:S8-S17. 2005
    ..Lack of awareness of the disease and its consequences prevents widespread use of drugs with anti-fracture efficacy. This limits their potential to reduce costs...
  3. doi request reprint [Osteoporosis - whom to treat? The importance of FRAX® in Switzerland]
    Kurt Lippuner
    Universitätspoliklinik für Osteoporose, Inselspital, Bern
    Ther Umsch 69:207-13. 2012
    ....
  4. pmc Recommendations for raloxifene use in daily clinical practice in the Swiss setting
    Kurt Lippuner
    Universitätspoliklinik für Osteoporose, Inselspital Bern, 3010 Bern, Switzerland
    Eur Spine J 21:2407-17. 2012
    ..The aim was to characterize the clinical profiles of postmenopausal women expected to benefit most from therapy with raloxifene based on published scientific evidence to date...
  5. doi request reprint Cost-effective intervention thresholds against osteoporotic fractures based on FRAX® in Switzerland
    K Lippuner
    Osteoporosis Policlinic, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland
    Osteoporos Int 23:2579-89. 2012
    ..Assuming a willingness to pay at 2× Gross Domestic Product per capita, an intervention aimed at reducing fracture risk in women and men with a 10-year probability for a major osteoporotic fracture at or above 15% is cost-effective...
  6. doi request reprint The future of osteoporosis treatment - a research update
    Kurt Lippuner
    Osteoporosis Policlinic, Inselspital, Bern University Hospital and University of Bern, Switzerland
    Swiss Med Wkly 142:w13624. 2012
    ..The WHO fracture risk assessment tool FRAX® and improved access to bone mineral density measurements by DXA will play a key role in this regard...
  7. doi request reprint [Epidemiology and burden of osteoporosis in Switzerland]
    Kurt Lippuner
    Universitätspoliklinik für Osteoporose, Inselspital, Bern
    Ther Umsch 69:137-44. 2012
    ..Should appropriate measures not be implemented in the near future, so will osteoporosis become one of the key challenges for the Swiss healthcare system within the coming years...
  8. doi request reprint Comparative trends in hospitalizations for osteoporotic fractures and other frequent diseases between 2000 and 2008
    K Lippuner
    Osteoporosis Policlinic, Inselspital, Bern University Hospital and University of Bern, CH 3010 Bern, Switzerland
    Osteoporos Int 23:829-39. 2012
    ..Similar trend patterns were observed for hip fractures and strokes (decrease) and nonhip fractures and acute myocardial infarctions (increase)...
  9. ncbi request reprint Fracture hospitalizations between years 2000 and 2007 in Switzerland: a trend analysis
    K Lippuner
    Osteoporosis Policlinic, Inselspital, Bern University Hospital, University of Bern, 3010, Bern, Switzerland
    Osteoporos Int 22:2487-97. 2011
    ..The cost impact of shorter hospital stays was offset by the increasing cost per day of hospitalization...
  10. ncbi request reprint [Epidemiology of osteoporotic fractures in Switzerland]
    K Lippuner
    Policlinique pour l ostéoporose, Hôpital de l lle de Berne, Hôpital universitaire et Université de Berne, Berne
    Rev Med Suisse 5:1304-8. 2009
    ..With FRAX (fracture risk assessment tool), validated for Switzerland in tight collaboration with the World Heath Organization, the individual probability of fracture during the next 10 years can be predicted...
  11. doi request reprint FRAX assessment of osteoporotic fracture probability in Switzerland
    K Lippuner
    Osteoporosis Policlinic, Inselspital, Bern University Hospital and University of Bern, 3010, Bern, Switzerland
    Osteoporos Int 21:381-9. 2010
    ..Patient profiles at increased probability of fracture beyond currently accepted reimbursement thresholds for bone mineral density (BMD) measurement by dual X-ray absorptiometry (DXA), and osteoporosis treatment were identified...
  12. doi request reprint Remaining lifetime and absolute 10-year probabilities of osteoporotic fracture in Swiss men and women
    K Lippuner
    Osteoporosis Policlinic, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland
    Osteoporos Int 20:1131-40. 2009
    ..Remaining lifetime probability at age 50 years was 20.2% in men and 51.3% in women and increased with advancing age and decreasing BMD. The study validates the elements required to populate a Swiss-specific FRAX model...
  13. pmc Medical treatment of vertebral osteoporosis
    K Lippuner
    Osteoporosis Policlinic, University Hospital of Berne, 3010, Berne, Switzerland
    Eur Spine J 12:S132-41. 2003
    ..Although reduction of vertebral fracture risk is an important criterion for decision making, drugs with proven additional fracture risk reduction at all clinically relevant sites (especially at the hip) should be the preferred options...
  14. doi request reprint Tibial or hip BMD predict clinical fracture risk equally well: results from a prospective study in 700 elderly Swiss women
    A W Popp
    Osteoporosis Policlinic, Inselspital, Bern University Hospital and University of Bern, CH 3010 Bern, Switzerland
    Osteoporos Int 20:1393-9. 2009
    ..Bone mineral density (BMD) measured at tibial diaphysis (T-DIA) and tibial epiphysis (T-EPI) using dual-energy X-ray absorptiometry (DXA) was shown to be a valid alternative to lumbar spine or hip BMD in predicting fractures...
  15. doi request reprint Experimental arthritis: effect on growth parameters and total skeletal calcium
    E Del Pozo
    Osteoporosis Policlinic, University Hospital, Bern, Switzerland
    Growth Horm IGF Res 19:442-6. 2009
    ..Generalized osteopenia is a prominent feature seemingly connected with the growth abnormalities as they parallel each other during the evolution of the disease and respond equally to therapy...
  16. pmc Augmentation of mechanical properties in osteoporotic vertebral bones--a biomechanical investigation of vertebroplasty efficacy with different bone cements
    P F Heini
    Department of Orthopaedic Surgery, Spine Service, Inselspital, University of Bern, Freiburgstrasse, 3010 Bern, Switzerland
    Eur Spine J 10:164-71. 2001
    ..Both PMMA and EBC augmentation reliably and significantly raised the stiffness and maximal tolerable force until failure in osteoporotic vertebral bodies. In non-porotic specimens, no significant increase was achieved...
  17. ncbi request reprint Imipramine and diet counseling with psychological support in the treatment of obese binge eaters: a randomized, placebo-controlled double-blind study
    K Laederach-Hofmann
    Unit for Psychosomatic and Psychosocial Medicine, University of Berne, Berne, Switzerland
    Int J Eat Disord 26:231-44. 1999
    ..This was followed by an open medication-free phase of 6 months of continuous diet counseling with psychological support...
  18. ncbi request reprint Comparative effects of teriparatide and ibandronate on spine bone mineral density (BMD) and microarchitecture (TBS) in postmenopausal women with osteoporosis: a 2-year open-label study
    C Senn
    Department of Osteoporosis, Inselspital, Berne University Hospital and University of Berne, CH 3010, Berne, Switzerland
    Osteoporos Int 25:1945-51. 2014
    ..Teriparatide induced larger increases in BMD and TBS compared to ibandronate, suggesting a more pronounced effect on bone microarchitecture of the bone anabolic drug...
  19. doi request reprint Cortical bone loss at the tibia in postmenopausal women with osteoporosis is associated with incident non-vertebral fractures: results of a randomized controlled ancillary study of HORIZON
    A W Popp
    Department of Osteoporosis, Inselspital, Berne University Hospital and University of Berne, Switzerland
    Maturitas 77:287-93. 2014
    ..The effects of ZOL on BMD at the tibial epiphysis (T-EPI) and diaphysis (T-DIA) are unknown...
  20. ncbi request reprint Graded doses of recombinant interleukin-1beta induce generalized osteopenia in rats without altering skeletal growth and joint integrity
    E Del Pozo
    Osteoporosis Policlinic, University Hospital of Bern, Switzerland
    Horm Res 64:88-95. 2005
    ....
  21. ncbi request reprint Postpartum osteoporosis associated with proximal tibial stress fracture
    I A Clemetson
    Department of Radiology, University Hospital of Bern, Inselspital, 3010, Bern, Switzerland
    Skeletal Radiol 33:96-8. 2004
    ..We discuss the presence of a postpartum stress fracture in a hitherto undescribed site in a patient who had lactated following an uncomplicated pregnancy and had no other identifiable cause for a stress fracture...
  22. ncbi request reprint The relative importance of vertebral bone density and disc degeneration in spinal flexibility and interbody implant performance. An in vitro study
    T R Oxland
    , University of Bern, Switzerland
    Spine (Phila Pa 1976) 21:2558-69. 1996
    ....
  23. ncbi request reprint Aromatase deficiency in a female who is compound heterozygote for two new point mutations in the P450arom gene: impact of estrogens on hypergonadotropic hypogonadism, multicystic ovaries, and bone densitometry in childhood
    P E Mullis
    Division of Paediatric Endocrinology, University Children s Hospital, Bern, Switzerland
    J Clin Endocrinol Metab 82:1739-45. 1997
    ....
  24. ncbi request reprint Which factors account for renal stone formation in cystic fibrosis?
    R von der Heiden
    Department of Pediatrics, University Hospital, Berne, Switzerland
    Clin Nephrol 59:160-3. 2003
    ..It is well recognized, however, that low urine volume, hypocitraturia and perhaps even hypercalciuria are further risk factors for stone formation...
  25. pmc Glucocorticosteroid-induced spinal osteoporosis: scientific update on pathophysiology and treatment
    Albrecht W Popp
    Osteoporosis Policlinic, University Hospital of Berne, 3010 Berne, Switzerland
    Eur Spine J 15:1035-49. 2006
    ..Kyphoplasty performed in appropriately selected osteoporotic patients with painful vertebral fractures is a promising addition to current medical treatment...
  26. ncbi request reprint Cortical and trabecular bone mineral density in transsexuals after long-term cross-sex hormonal treatment: a cross-sectional study
    Adrian G Ruetsche
    Osteoporosis Unit, University Hospital of Berne, CH 3010 Berne, Switzerland
    Osteoporos Int 16:791-8. 2005
    ..6 years of androgen treatment in this cross sectional study. IGF-1 could play a role in the mediation of the effect of androgens on bone in F-M transsexuals...
  27. ncbi request reprint Osteoporosis case finding in the general practice: phalangeal radiographic absorptiometry with and without risk factors for osteoporosis to select postmenopausal women eligible for lumbar spine and hip densitometry
    Katharina M Gasser
    Osteoporosis Policlinic, University Hospital of Berne, Switzerland
    Osteoporos Int 16:1353-62. 2005
    ..In the Swiss environment, RA is a valid case finding tool for patients with risk factors for osteoporosis, especially for those who do not qualify for DXA reimbursement...
  28. ncbi request reprint A model of osteoporosis impact in Switzerland 2000-2020
    Matthias Schwenkglenks
    ECPM Executive Office, University Hospital, 4031, Basle, Switzerland
    Osteoporos Int 16:659-71. 2005
    ..Corresponding absolute fracture numbers will rise by 36%, 31%, and 23%. Related direct medical inpatient costs are predicted to increase by 33%; however, this estimate is subject to uncertainty due to limited availability of input data...
  29. ncbi request reprint Alendronate with and without cholecalciferol for osteoporosis: results of a 15-week randomized controlled trial
    Robert Recker
    Creighton University, Osteoporosis Research Center, Omaha, NE, USA
    Curr Med Res Opin 22:1745-55. 2006
    ..This study assessed the efficacy, safety, and tolerability of a once-weekly tablet containing alendronate 70 mg and cholecalciferol 70 microg (2800 IU) (ALN + D) versus alendronate 70 mg alone (ALN)...
  30. ncbi request reprint Biologically relevant sex differences for fitness-related parameters in active octogenarians
    Fabian Lötscher
    Institute of Anatomy, University of Bern, Baltzerstrasse 2, 3000, Bern 9, Switzerland
    Eur J Appl Physiol 99:533-40. 2007
    ....
  31. ncbi request reprint Prevention of postmenopausal bone loss with long-cycle hormone replacement therapy
    Albrecht W E Popp
    Osteoporosis Policlinic, University Hospital of Berne, Switzerland
    Maturitas 53:191-200. 2006
    ..The effects on bone of such long-cycle HRT regimens are unknown. The objective of the present study was to compare the effects on bone and the endometrium of long-cycle HRT and conventional HRT...
  32. ncbi request reprint Long-term changes in bone metabolism, bone mineral density, quantitative ultrasound parameters, and fracture incidence after spinal cord injury: a cross-sectional observational study in 100 paraplegic men
    Yvonne Zehnder
    Swiss Paraplegic Center, CH 6207, Nottwil, Switzerland
    Osteoporos Int 15:180-9. 2004
    ..In paraplegic men early (trabecular) and persistent (cortical) bone loss occurs at the lower limbs and leads to an increasing fracture incidence with time-after-SCI...
  33. ncbi request reprint 1,25-(OH)2-16ene-23yne-D3 reduces secondary hyperparathyroidism in uremic rats with little calcemic effect
    Kurt Lippuner
    Osteoporosis Unit Policlinic of Medicine, University Hospital of Berne, Berne, Switzerland
    Horm Res 61:7-16. 2004
    ..A compound better than calcitriol should increase the Ca x P product less than calcitriol for an equivalent decrease in PTH levels...
  34. ncbi request reprint Prediction of hip fracture risk by quantitative ultrasound in more than 7000 Swiss women > or =70 years of age: comparison of three technologically different bone ultrasound devices in the SEMOF study
    Marc Antoine Krieg
    Department of Internal Medicine, University Hospital, Lausanne, Switzerland
    J Bone Miner Res 21:1457-63. 2006
    ..Heel QUSs were both predictive of hip fracture risk, whereas the phalanges QUS was not...
  35. ncbi request reprint Changes in bone mineral density over 18 months following kidney transplantation: the respective roles of prednisone and parathyroid hormone
    Jean Paul Casez
    Department of Nephrology, University of Nice, France
    Nephrol Dial Transplant 17:1318-26. 2002
    ..Prednisone is a major factor of bone loss after kidney transplantation. The role of hyperparathyroidism and immunosuppressors is less clear...