Roger Lehmann

Summary

Affiliation: University Hospital
Country: Switzerland

Publications

  1. ncbi request reprint [Islet transplantation in type I diabetes mellitus]
    R Lehmann
    Abteilung Endokrinologie und Diabetologie, Departement für Innere Medizin Universitätsspital Zürich, Zurich
    Ther Umsch 62:481-6. 2005
  2. doi request reprint [End-stage nephropathy in type 1-diabetes mellitus - kidney transplantation alone or combined with islet or pancreas transplantation?]
    Roger Lehman
    Klinik fur Endokrinologie, Diabetologie und Klinische Ernährung, Universitatsspital Zurich, Zurich
    Ther Umsch 68:699-706. 2011
  3. doi request reprint Has time come for new goals in human islet transplantation?
    R Lehmann
    University Hospital Zurich, Islet Transplant Program, Zurich, Switzerland
    Am J Transplant 8:1096-100. 2008
  4. ncbi request reprint Superiority of small islets in human islet transplantation
    Roger Lehmann
    Clinical Islet Transplantation Program, Department of Endocrinology and Diabetes, University Hospital Zurich, Raemistrasse 100, CH 8091 Zurich, Switzerland
    Diabetes 56:594-603. 2007
  5. ncbi request reprint Successful simultaneous islet-kidney transplantation using a steroid-free immunosuppression: two-year follow-up
    Roger Lehmann
    Departments of Radiology and Visceral Surgery, University Hospital, CH 8091 Zurich, Switzerland
    Am J Transplant 4:1117-23. 2004
  6. doi request reprint [New insights into diagnosis and management of gestational diabetes mellitus: recommendations of the Swiss Society for Endocrinology and Diabetes]
    Roger Lehmann
    Klinik fur Endokrinologie, Diabetologie und Klinische Ernährung, Universitatsspital Zurich
    Ther Umsch 66:695-706. 2009
  7. doi request reprint Diet determines features of the metabolic syndrome in 6- to 14-year-old children
    Isabelle Aeberli
    Human Nutrition Laboratory, Institute of Food Science and Nutrition, ETH Zurich, Zurich, Switzerland
    Int J Vitam Nutr Res 79:14-23. 2009
  8. ncbi request reprint Fructose intake is a predictor of LDL particle size in overweight schoolchildren
    Isabelle Aeberli
    Human Nutrition Laboratory, Institute of Food Science and Nutrition, ETH Zurich, Zurich, Switzerland
    Am J Clin Nutr 86:1174-8. 2007
  9. ncbi request reprint Central necrosis in isolated hypoxic human pancreatic islets: evidence for postisolation ischemia
    Mauro Giuliani
    Department of Visceral and Transplant Surgery, University Hospital Zurich, 8091 Zurich, Switzerland
    Cell Transplant 14:67-76. 2005
  10. doi request reprint Insulin sensitivity in type 2 diabetes is closely associated with LDL particle size
    Pierre A Krayenbuehl
    Department of Internal Medicine, Medical Policlinic, University Hospital Zurich, Zurich, Switzerland
    Swiss Med Wkly 138:275-80. 2008

Collaborators

Detail Information

Publications26

  1. ncbi request reprint [Islet transplantation in type I diabetes mellitus]
    R Lehmann
    Abteilung Endokrinologie und Diabetologie, Departement für Innere Medizin Universitätsspital Zürich, Zurich
    Ther Umsch 62:481-6. 2005
    ..The choice between islet or pancreas transplantation is a matter of age and diabetic complications because the perioperative risk is considerably higher in pancreas transplantation...
  2. doi request reprint [End-stage nephropathy in type 1-diabetes mellitus - kidney transplantation alone or combined with islet or pancreas transplantation?]
    Roger Lehman
    Klinik fur Endokrinologie, Diabetologie und Klinische Ernährung, Universitatsspital Zurich, Zurich
    Ther Umsch 68:699-706. 2011
    ..In this review article the advantages, disadvantages, and current indications for both beta-cell replacement options in Switzerland are discussed in the light of the available evidence with the help of a new flow chart...
  3. doi request reprint Has time come for new goals in human islet transplantation?
    R Lehmann
    University Hospital Zurich, Islet Transplant Program, Zurich, Switzerland
    Am J Transplant 8:1096-100. 2008
    ..Transplantation of smaller islets be it naturally small or size tailored reaggregated islets has the potential to facilitate these processes...
  4. ncbi request reprint Superiority of small islets in human islet transplantation
    Roger Lehmann
    Clinical Islet Transplantation Program, Department of Endocrinology and Diabetes, University Hospital Zurich, Raemistrasse 100, CH 8091 Zurich, Switzerland
    Diabetes 56:594-603. 2007
    ..Thus, islet size seems to be a key factor determining human islet transplantation outcome...
  5. ncbi request reprint Successful simultaneous islet-kidney transplantation using a steroid-free immunosuppression: two-year follow-up
    Roger Lehmann
    Departments of Radiology and Visceral Surgery, University Hospital, CH 8091 Zurich, Switzerland
    Am J Transplant 4:1117-23. 2004
    ....
  6. doi request reprint [New insights into diagnosis and management of gestational diabetes mellitus: recommendations of the Swiss Society for Endocrinology and Diabetes]
    Roger Lehmann
    Klinik fur Endokrinologie, Diabetologie und Klinische Ernährung, Universitatsspital Zurich
    Ther Umsch 66:695-706. 2009
    ..Insulin therapy is still the preferred treatment option, but metformin (and as an exception glibenclamide) can be used, if there are major hurdles for the initiation of insulin therapy...
  7. doi request reprint Diet determines features of the metabolic syndrome in 6- to 14-year-old children
    Isabelle Aeberli
    Human Nutrition Laboratory, Institute of Food Science and Nutrition, ETH Zurich, Zurich, Switzerland
    Int J Vitam Nutr Res 79:14-23. 2009
    ..Therefore, the objective of this study was to investigate dietary determinants of IR, BP, resistin, adiponectin, and leptin concentrations, as well as the interrelationship among these variables, in normal and overweight children...
  8. ncbi request reprint Fructose intake is a predictor of LDL particle size in overweight schoolchildren
    Isabelle Aeberli
    Human Nutrition Laboratory, Institute of Food Science and Nutrition, ETH Zurich, Zurich, Switzerland
    Am J Clin Nutr 86:1174-8. 2007
    ..Childhood adiposity is associated with smaller LDL particle size, but the dietary predictors of LDL size in overweight children have not been studied...
  9. ncbi request reprint Central necrosis in isolated hypoxic human pancreatic islets: evidence for postisolation ischemia
    Mauro Giuliani
    Department of Visceral and Transplant Surgery, University Hospital Zurich, 8091 Zurich, Switzerland
    Cell Transplant 14:67-76. 2005
    ....
  10. doi request reprint Insulin sensitivity in type 2 diabetes is closely associated with LDL particle size
    Pierre A Krayenbuehl
    Department of Internal Medicine, Medical Policlinic, University Hospital Zurich, Zurich, Switzerland
    Swiss Med Wkly 138:275-80. 2008
    ..Small dense LDLs have been found to be associated with type 2 diabetes (T2DM). This association has been observed in the context of decreased HDL cholesterol and increased triglycerides...
  11. doi request reprint Regional differences of glycaemic control in patients with type 2 diabetes mellitus in Switzerland: a national cross-sectional survey
    Philipp Andreas Gerber
    Department of Endocrinology and Diabetes, University Hospital Zurich, Raemistrasse 100, CH 8091 Zurich, Switzerland
    Swiss Med Wkly 141:w13218. 2011
    ..We investigated contemporary diabetes care, quality of glycaemic control, and progression of obesity in patients with diabetes mellitus in different cultural regions within Switzerland...
  12. doi request reprint Donor-derived aspergillosis from use of a solid organ recipient as a multiorgan donor
    N J Mueller
    Department of Medicine, Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Zurich, Switzerland
    Transpl Infect Dis 12:54-9. 2010
    ..Despite the pressure to extend the use of organs by lowering the acceptance criteria, organs should only be accepted if the cause of death of the donors is unequivocally explained...
  13. ncbi request reprint Apoptosis in hypoxic human pancreatic islets correlates with HIF-1alpha expression
    Wolfgang Moritz
    Clinic for Visceral and Transplant Surgery, University Hospital Zurich, CH 8091 Zurich, Switzerland
    FASEB J 16:745-7. 2002
    ..These observations suggest that gene expression under the control of HIF-1 represents a potential therapeutic tool for improving engraftment of transplanted islets...
  14. ncbi request reprint Dietary intakes of fat and antioxidant vitamins are predictors of subclinical inflammation in overweight Swiss children
    Isabelle Aeberli
    Human Nutrition Laboratory, Institute of Food Science and Nutrition, Swiss Federal Institute of Technology, Zurich, Switzerland
    Am J Clin Nutr 84:748-55. 2006
    ..Dietary factors, such as fatty acids and antioxidants, potentially modulate the association between adiposity and subclinical inflammation, but few data are available in children...
  15. ncbi request reprint Simultaneous islet-kidney vs pancreas-kidney transplantation in type 1 diabetes mellitus: a 5 year single centre follow-up
    P A Gerber
    Department of Endocrinology and Diabetes, University Hospital Zurich, Raemistrasse 100, CH 8091, Zurich, Switzerland
    Diabetologia 51:110-9. 2008
    ....
  16. pmc FLIP switches Fas-mediated glucose signaling in human pancreatic beta cells from apoptosis to cell replication
    Kathrin Maedler
    Divisions of Endocrinology and Diabetes and Clinical Immunology, University Hospital, Zurich CH 8091, Switzerland
    Proc Natl Acad Sci U S A 99:8236-41. 2002
    ..The present data provide evidence for expression of FLIP in the human beta cell and suggest a novel approach to prevent and treat diabetes by switching Fas signaling from apoptosis to proliferation...
  17. ncbi request reprint Factors associated with the incidence of type 2 diabetes mellitus in HIV-infected participants in the Swiss HIV Cohort Study
    Bruno Ledergerber
    Division of Infectious Diseases and Hospital Epidemiology, University Hospital, Zurich, Switzerland
    Clin Infect Dis 45:111-9. 2007
    ..Human immunodeficiency virus (HIV)-infected persons may be at increased risk for developing type 2 diabetes mellitus because of viral coinfection and adverse effects of treatment...
  18. ncbi request reprint Clinical and technical evaluation of a new self-monitoring blood glucose meter: assessment of analytical and user error
    R Lehmann
    Department of Internal Medicine, Division of Endocrinology and Diabetes, University Hospital, CH 8091, Zurich, Switzerland
    Diabetes Res Clin Pract 53:121-8. 2001
    ..The results indicate that that the MediSense QID/Precision Plus Electrodes is a reliable and easy to use device, which can be recommended for the majority of patients with diabetes mellitus...
  19. ncbi request reprint Effect of losartan, compared with atenolol, on endothelial function and oxidative stress in patients with type 2 diabetes and hypertension
    Andreas J Flammer
    Cardiovascular Center, Cardiology, University Hospital Zurich, Switzerland
    J Hypertens 25:785-91. 2007
    ..We investigated the influence of losartan, compared with atenolol, on endothelial function and oxidative stress in patients with type 2 diabetes and hypertension...
  20. ncbi request reprint Glucose control is not improved by accelerating gastric emptying in patients with type 1 diabetes mellitus and gastroparesis. a pilot study with cisapride as a model drug
    R Lehmann
    Division of Endocrinology and Diabetes, Department of Internal Medicine, University Hospital, Zurich, Switzerland
    Exp Clin Endocrinol Diabetes 111:255-61. 2003
    ..We do not recommend, therefore, acceleration of gastric emptying as treatment strategy for "brittle diabetes" in patients with type 1 diabetes...
  21. ncbi request reprint A plasma glucose concentration below 2.5 mmol L-1 is not an appropriate criterion to end the 72-h fast
    P Wiesli
    Department of Internal Medicine, Division of Endocrinology and Diabetes, University Hospital, CH 8091 Zurich, Switzerland
    J Intern Med 252:504-9. 2002
    ..However, neither the symptoms nor the plasma glucose level have been exactly defined...
  22. ncbi request reprint Assessment of basal insulin requirement using fasting tests in insulin-treated patients with type 2 diabetes mellitus
    P Wiesli
    Department of Internal Medicine, Division of Endocrinology and Diabetes, University Hospital, Zurich, Switzerland
    Exp Clin Endocrinol Diabetes 114:539-43. 2006
    ..Characterizing the time course of the rise of blood glucose concentrations in the fasting state during the day and night in patients with type 2 diabetes...
  23. ncbi request reprint Diminished insulin secretory response to glucose but normal insulin and glucagon secretory responses to arginine in a family with maternally inherited diabetes and deafness caused by mitochondrial tRNA(LEU(UUR)) gene mutation
    M Brandle
    Division of Endocrinology and Diabetes, Department of Internal Medicine, University Hospital, Zurich, Switzerland
    Diabetes Care 24:1253-8. 2001
    ..The effects of glucose, arginine, and glucagon on beta-cell function as well as alpha-cell response to arginine were studied in a family with mitochondrial diabetes...
  24. ncbi request reprint [Screening, diagnosis and management of diabetes mellitus and diabetic complications]
    R Lehmann
    Abteilung Endokrinologie und Diabetologie, Universitatsspital Zurich
    Ther Umsch 57:12-21. 2000
    ..Often a combination therapy with many different drugs is required. 6) A specialist for diabetes should be consulted, if the therapeutic goals can not be met over a period of six months...
  25. ncbi request reprint Expression and hypoxic regulation of the endothelin system in endocrine cells of human and rat pancreatic islets
    Patrick Kugelmeier
    Clinic for Visceral and Transplant Surgery, Department of Surgery, Zurich University Hospital Zurich, Switzerland
    JOP 9:133-49. 2008
    ....
  26. ncbi request reprint Serum retinol-binding protein 4 concentration and its ratio to serum retinol are associated with obesity and metabolic syndrome components in children
    Isabelle Aeberli
    Human Nutrition Laboratory, Institute of Food Science and Nutrition, Swiss Federal Institute of Technology Zurich, 8092 Zurich, Switzerland
    J Clin Endocrinol Metab 92:4359-65. 2007
    ..There are few published data on RBP4 levels in overweight children, and most previous studies did not control for vitamin A (VA) status and/or subclinical inflammation...