R Kunz

Summary

Affiliation: University Hospital
Country: Switzerland

Publications

  1. ncbi request reprint Renoprotective effects of renin-angiotensin-system inhibitors
    Johannes F E Mann
    Lancet 367:900; author reply 900-2. 2006
  2. ncbi request reprint Progression of renal disease--can we forget about inhibition of the renin-angiotensin system?
    Johannes F E Mann
    Nephrol Dial Transplant 21:2348-51; discussion 2352-3. 2006
  3. doi request reprint Randomized trials and observational studies: still mostly similar results, still crucial differences
    Regina Kunz
    Basel Institute for Clinical Epidemiology, University Hospital Basel, Hebelstrasse 10, 4031 Basel, Switzerland
    J Clin Epidemiol 61:207-8. 2008
  4. pmc Evaluation of work disability and the international classification of functioning, disability and health: what to expect and what not
    Jessica Anner
    asim, Academy of Swiss Insurance Medicine, University Hospital Basel, Basel, Switzerland
    BMC Public Health 12:470. 2012
  5. pmc Perioperative management of antithrombotic therapy: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines
    James D Douketis
    Department of Medicine, McMaster University, Hamilton, ON, Canada
    Chest 141:e326S-50S. 2012
  6. pmc Stopping randomized trials early for benefit: a protocol of the Study Of Trial Policy Of Interim Truncation-2 (STOPIT-2)
    Matthias Briel
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Canada
    Trials 10:49. 2009
  7. pmc How are "teaching the teachers" courses in evidence based medicine evaluated? A systematic review
    Jacek Walczak
    CASPolska, 32 400 Myślenice, ul, Mickiewicza 40, Poland
    BMC Med Educ 10:64. 2010
  8. pmc The effectiveness of a clinically integrated e-learning course in evidence-based medicine: a cluster randomised controlled trial
    Regina Kulier
    The University of Birmingham, Edgbaston, Birmingham B15 2TG, UK
    BMC Med Educ 9:21. 2009
  9. pmc A clinically integrated curriculum in evidence-based medicine for just-in-time learning through on-the-job training: the EU-EBM project
    Sjors F P J Coppus
    Academic Medical Center, University of Amsterdam, Department of Obstetrics and Gynaecology, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    BMC Med Educ 7:46. 2007
  10. pmc Harmonising evidence-based medicine teaching: a study of the outcomes of e-learning in five European countries
    Regina Kulier
    The University of Birmingham, Edgbaston, Birmingham B15 2TG, UK
    BMC Med Educ 8:27. 2008

Detail Information

Publications36

  1. ncbi request reprint Renoprotective effects of renin-angiotensin-system inhibitors
    Johannes F E Mann
    Lancet 367:900; author reply 900-2. 2006
  2. ncbi request reprint Progression of renal disease--can we forget about inhibition of the renin-angiotensin system?
    Johannes F E Mann
    Nephrol Dial Transplant 21:2348-51; discussion 2352-3. 2006
  3. doi request reprint Randomized trials and observational studies: still mostly similar results, still crucial differences
    Regina Kunz
    Basel Institute for Clinical Epidemiology, University Hospital Basel, Hebelstrasse 10, 4031 Basel, Switzerland
    J Clin Epidemiol 61:207-8. 2008
  4. pmc Evaluation of work disability and the international classification of functioning, disability and health: what to expect and what not
    Jessica Anner
    asim, Academy of Swiss Insurance Medicine, University Hospital Basel, Basel, Switzerland
    BMC Public Health 12:470. 2012
    ..We describe core features of disability evaluation of the ICF across countries. We address how and to what extent the ICF may be applied in disability evaluation...
  5. pmc Perioperative management of antithrombotic therapy: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines
    James D Douketis
    Department of Medicine, McMaster University, Hamilton, ON, Canada
    Chest 141:e326S-50S. 2012
    ..This guideline addresses the management of patients who are receiving anticoagulant or antiplatelet therapy and require an elective surgery or procedure...
  6. pmc Stopping randomized trials early for benefit: a protocol of the Study Of Trial Policy Of Interim Truncation-2 (STOPIT-2)
    Matthias Briel
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Canada
    Trials 10:49. 2009
    ..The aim of STOPIT-2 is to determine the magnitude and determinants of possible bias introduced by stopping RCTs early for benefit...
  7. pmc How are "teaching the teachers" courses in evidence based medicine evaluated? A systematic review
    Jacek Walczak
    CASPolska, 32 400 Myślenice, ul, Mickiewicza 40, Poland
    BMC Med Educ 10:64. 2010
    ..We conducted a systematic review of assessment tools for EBM TTT courses. To summarise and appraise existing assessment methods for teaching the teachers courses in EBM by a systematic review...
  8. pmc The effectiveness of a clinically integrated e-learning course in evidence-based medicine: a cluster randomised controlled trial
    Regina Kulier
    The University of Birmingham, Edgbaston, Birmingham B15 2TG, UK
    BMC Med Educ 9:21. 2009
    ..To evaluate the educational effects of a clinically integrated e-learning course for teaching basic evidence-based medicine (EBM) among postgraduates compared to a traditional lecture-based course of equivalent content...
  9. pmc A clinically integrated curriculum in evidence-based medicine for just-in-time learning through on-the-job training: the EU-EBM project
    Sjors F P J Coppus
    Academic Medical Center, University of Amsterdam, Department of Obstetrics and Gynaecology, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    BMC Med Educ 7:46. 2007
    ..We aimed to develop a course for post-graduate education which is clinically integrated and allows maximum flexibility for teachers and learners...
  10. pmc Harmonising evidence-based medicine teaching: a study of the outcomes of e-learning in five European countries
    Regina Kulier
    The University of Birmingham, Edgbaston, Birmingham B15 2TG, UK
    BMC Med Educ 8:27. 2008
    ..We developed and evaluated the outcomes of an e-learning course for evidence based medicine (EBM) training in postgraduate medical education in different languages and settings across five European countries...
  11. pmc Impact of short evidence summaries in discharge letters on adherence of practitioners to discharge medication. A cluster-randomised controlled trial
    R Kunz
    Basel Institute for Clinical Epidemiology, University Hospital Basel, Hebelstrasse 10, CH 4031 Basel, Switzerland
    Qual Saf Health Care 16:456-61. 2007
    ..International concern about quality of medical care has led to intensive study of interventions to ensure care is consistent with best evidence. Simple, inexpensive, feasible and effective interventions remain limited...
  12. doi request reprint [The GRADE System. An international approach to standardize the graduation of evidence and recommendations in guidelines]
    R Kunz
    Basel Institut für Klinische Epidemiologie, Universitatsspital Basel, Hebelstrasse 19, 4031, Basel, Switzerland
    Internist (Berl) 49:673-80. 2008
    ..Many guideline organizations and medical societies have endorsed the system and adopted it for their guideline processes...
  13. doi request reprint Misconceptions, challenges, uncertainty, and progress in guideline recommendations
    Regina Kunz
    Basel Institute of Clinical Epidemiology, University Hospital Basel, Basel, Switzerland
    Semin Hematol 45:167-75. 2008
    ..Many guideline organizations and medical societies have endorsed the system and adopted it for their guideline processes...
  14. doi request reprint How far did we get? How far to go? A European survey on postgraduate courses in evidence-based medicine
    Regina Kunz
    Basel Institute for Clinical Epidemiology BICE, University Hospital Basel, Basel, Switzerland
    J Eval Clin Pract 15:1196-204. 2009
    ..However, little is known about learning opportunities to acquire EBM-associated skills. The EUebm-Unity partnership explored current educational activities for EBM practice for doctors across Europe...
  15. ncbi request reprint Meta-analysis: effect of monotherapy and combination therapy with inhibitors of the renin angiotensin system on proteinuria in renal disease
    Regina Kunz
    Basel Institute for Clinical Epidemiology and Clinic for Transplantation Immunology and Nephrology, University Hospital Basel, Basel, Switzerland
    Ann Intern Med 148:30-48. 2008
    ..Reports suggest that angiotensin-receptor blockers (ARBs) reduce proteinuria, but results are variable. The relative effect of ARBs and angiotensin-converting enzyme (ACE) inhibitors, and their combined administration, remains uncertain...
  16. ncbi request reprint A systematic review finds that methodological quality is better than its reputation but can be improved in physiotherapy trials in childhood cerebral palsy
    Regina Kunz
    Basel Institute for Clinical Epidemiology, University Hospital of Basel, Hebelstrasse 10, 4031 Basel, Switzerland
    J Clin Epidemiol 59:1239-48. 2006
    ....
  17. ncbi request reprint [How many standards can variety take?]
    Regina Kunz
    Arbeitsgemeinschaft Koordinierungsausschuss, Auf dem Seidenberg 3a, 53721 Siegburg
    Z Arztl Fortbild Qualitatssich 97:291-4. 2003
    ..In this article, authors of the curriculum provide a replique to the criticisms...
  18. pmc What is "quality of evidence" and why is it important to clinicians?
    Gordon H Guyatt
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada L8N 3Z5
    BMJ 336:995-8. 2008
  19. ncbi request reprint [Last but not least--the German Network EbM has got its glossary on EbM terms]
    Regina Kunz
    Gemeinsamer Bundesausschuss, Siegburg
    Z Arztl Fortbild Qualitatssich 98:429-35. 2004
    ..ebm-netzwerk.de/glossar.htm. The present glossary is just a start, though. Over the coming years more terms will have to be added according to the needs and suggestions of our readership. We thus call on active participation of its users...
  20. ncbi request reprint Quality of reporting of randomized, controlled trials in cerebral palsy
    Heidi Anttila
    Finnish Office for Health Technology Assessment, National Research and Development Centre for Welfare and Health, Helsinki, Finland
    Pediatrics 117:2222-30. 2006
    ..Therefore, we set out to evaluate trial reporting by using the Consolidated Standards of Reporting Trials (CONSORT) statement recommendations...
  21. ncbi request reprint [The implementation of evidence-based medicine in general practice-acceptance and use of external information services]
    Aaron Juche
    Johanniter Krankenhaus im Fläming GmbH, Klinik I, Treuenbrietzen
    Z Arztl Fortbild Qualitatssich 100:383-7. 2006
    ..The demand for, and the potential of, evidence-based medicine (EBM) in everyday general practice have not been studied systematically yet...
  22. ncbi request reprint [Implementation of evidence-based medicine in clinical practice--external offers to search for and critically assess medical literature]
    Ulrike Euler
    Institut für Sozialmedizin, Epidemiologie und Gesundheitsökonomie, Klinikum Charite, Humboldt Universitat zu Berlin
    Z Arztl Fortbild Qualitatssich 96:325-31. 2002
    ..One to two weeks after we had supplied our answers, the influence our answers had had on the medical decisions taken and the overall satisfaction with our offer were evaluated using standardized questionnaires...
  23. ncbi request reprint An emerging consensus on grading recommendations?
    Gordon Guyatt
    McMaster University, Hamilton, Ontario, Canada
    ACP J Club 144:A8-9. 2006
  24. ncbi request reprint Integrating an evidence-based medicine rotation into an internal medicine residency program
    Elie A Akl
    Department of Medicine, University at Buffalo, ECMC CC 142, 462 Grider St, Buffalo, NY 14215, USA
    Acad Med 79:897-904. 2004
    ..To measure the impact of a resident focused evidence-based medicine (EBM) educational intervention on EBM knowledge of residents and students, to assess its feasibility, and to evaluate residents' attitudes regarding this rotation...
  25. ncbi request reprint An emerging consensus on grading recommendations?
    Gordon Guyatt
    McMaster University, Hamilton, Ontario, Canada
    Evid Based Med 11:2-4. 2006
  26. pmc Five steps to conducting a systematic review
    Khalid S Khan
    Education Resource Centre, Birmingham Women s Hospital, Birmingham B15 2TG, UK
    J R Soc Med 96:118-21. 2003
  27. doi request reprint How strong is the evidence?
    Yngve Falck-Ytter
    Division of Gastroenterology, Case Western Reserve University, Louis Stokes Cleveland VA Medical Center and Case Medical Center, Cleveland, Ohio, USA
    Am J Gastroenterol 103:1334-8. 2008
  28. pmc Incorporating considerations of resources use into grading recommendations
    Gordon H Guyatt
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada L8N 3Z5
    BMJ 336:1170-3. 2008
  29. pmc Grading quality of evidence and strength of recommendations for diagnostic tests and strategies
    Holger J Schunemann
    Department of Epidemiology, Italian National Cancer Institute Regina Elena, 00144 Rome, Italy
    BMJ 336:1106-10. 2008
  30. doi request reprint The COOPERATE trial: a letter of concern
    Regina Kunz
    Lancet 371:1575-6. 2008
  31. pmc Going from evidence to recommendations
    Gordon H Guyatt
    CLARITY Research Group, Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada L8N 3Z5
    BMJ 336:1049-51. 2008
  32. doi request reprint Point: evidence-based medicine has a sound scientific base
    Paul J Karanicolas
    Chest 133:1067-71. 2008
  33. ncbi request reprint Which patients to include in the analysis?
    Regina Kunz
    Transfusion 46:881-4. 2006
  34. pmc GRADE: an emerging consensus on rating quality of evidence and strength of recommendations
    Gordon H Guyatt
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada L8N 3Z5
    BMJ 336:924-6. 2008
  35. ncbi request reprint Evidence-based clinical practice guidelines for prostate cancer: the need for a unified approach
    Philipp Dahm
    Department of Urology, College of Medicine, University of Florida, Gainesville, Florida 32610 0247, USA
    Curr Opin Urol 17:200-7. 2007
    ..It further introduces the recommendations of the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) working group as a unified approach to guideline development...
  36. ncbi request reprint When small degrees of bias in randomized trials can mislead clinical decisions: an example of individualizing preventive treatment of upper gastrointestinal bleeding
    Regina Kunz
    Department of Internal Medicine, University Hospital Charite, Berlin, Germany
    Crit Care Med 30:1503-7. 2002
    ..The aim of this study is to assess under which circumstances clinicians need to be concerned about bias in clinical trials...