R Kunz

Summary

Affiliation: University Hospital
Country: Switzerland

Publications

  1. ncbi Renoprotective effects of renin-angiotensin-system inhibitors
    Johannes F E Mann
    Lancet 367:900; author reply 900-2. 2006
  2. ncbi Progression of renal disease--can we forget about inhibition of the renin-angiotensin system?
    Johannes F E Mann
    Nephrol Dial Transplant 21:2348-51; discussion 2352-3. 2006
  3. ncbi Randomized trials and observational studies: still mostly similar results, still crucial differences
    Regina Kunz
    Basel Institute for Clinical Epidemiology, University Hospital Basel, Hebelstrasse 10, 4031 Basel, Switzerland
    J Clin Epidemiol 61:207-8. 2008
  4. ncbi Perioperative management of antithrombotic therapy: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines
    James D Douketis
    Department of Medicine, McMaster University, Hamilton, ON, Canada
    Chest 141:e326S-50S. 2012
  5. ncbi Stopping randomized trials early for benefit: a protocol of the Study Of Trial Policy Of Interim Truncation-2 (STOPIT-2)
    Matthias Briel
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Canada
    Trials 10:49. 2009
  6. ncbi How are "teaching the teachers" courses in evidence based medicine evaluated? A systematic review
    Jacek Walczak
    CASPolska, 32 400 Myślenice, ul, Mickiewicza 40, Poland
    BMC Med Educ 10:64. 2010
  7. ncbi The effectiveness of a clinically integrated e-learning course in evidence-based medicine: a cluster randomised controlled trial
    Regina Kulier
    The University of Birmingham, Edgbaston, Birmingham B15 2TG, UK
    BMC Med Educ 9:21. 2009
  8. ncbi A clinically integrated curriculum in evidence-based medicine for just-in-time learning through on-the-job training: the EU-EBM project
    Sjors F P J Coppus
    Academic Medical Center, University of Amsterdam, Department of Obstetrics and Gynaecology, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    BMC Med Educ 7:46. 2007
  9. ncbi Harmonising evidence-based medicine teaching: a study of the outcomes of e-learning in five European countries
    Regina Kulier
    The University of Birmingham, Edgbaston, Birmingham B15 2TG, UK
    BMC Med Educ 8:27. 2008
  10. ncbi Impact of short evidence summaries in discharge letters on adherence of practitioners to discharge medication. A cluster-randomised controlled trial
    R Kunz
    Basel Institute for Clinical Epidemiology, University Hospital Basel, Hebelstrasse 10, CH 4031 Basel, Switzerland
    Qual Saf Health Care 16:456-61. 2007

Detail Information

Publications35

  1. ncbi Renoprotective effects of renin-angiotensin-system inhibitors
    Johannes F E Mann
    Lancet 367:900; author reply 900-2. 2006
  2. ncbi Progression of renal disease--can we forget about inhibition of the renin-angiotensin system?
    Johannes F E Mann
    Nephrol Dial Transplant 21:2348-51; discussion 2352-3. 2006
  3. ncbi Randomized trials and observational studies: still mostly similar results, still crucial differences
    Regina Kunz
    Basel Institute for Clinical Epidemiology, University Hospital Basel, Hebelstrasse 10, 4031 Basel, Switzerland
    J Clin Epidemiol 61:207-8. 2008
  4. ncbi Perioperative management of antithrombotic therapy: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines
    James D Douketis
    Department of Medicine, McMaster University, Hamilton, ON, Canada
    Chest 141:e326S-50S. 2012
    ..This guideline addresses the management of patients who are receiving anticoagulant or antiplatelet therapy and require an elective surgery or procedure...
  5. ncbi Stopping randomized trials early for benefit: a protocol of the Study Of Trial Policy Of Interim Truncation-2 (STOPIT-2)
    Matthias Briel
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Canada
    Trials 10:49. 2009
    ..The aim of STOPIT-2 is to determine the magnitude and determinants of possible bias introduced by stopping RCTs early for benefit...
  6. ncbi How are "teaching the teachers" courses in evidence based medicine evaluated? A systematic review
    Jacek Walczak
    CASPolska, 32 400 Myślenice, ul, Mickiewicza 40, Poland
    BMC Med Educ 10:64. 2010
    ..We conducted a systematic review of assessment tools for EBM TTT courses. To summarise and appraise existing assessment methods for teaching the teachers courses in EBM by a systematic review...
  7. ncbi The effectiveness of a clinically integrated e-learning course in evidence-based medicine: a cluster randomised controlled trial
    Regina Kulier
    The University of Birmingham, Edgbaston, Birmingham B15 2TG, UK
    BMC Med Educ 9:21. 2009
    ..To evaluate the educational effects of a clinically integrated e-learning course for teaching basic evidence-based medicine (EBM) among postgraduates compared to a traditional lecture-based course of equivalent content...
  8. ncbi A clinically integrated curriculum in evidence-based medicine for just-in-time learning through on-the-job training: the EU-EBM project
    Sjors F P J Coppus
    Academic Medical Center, University of Amsterdam, Department of Obstetrics and Gynaecology, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    BMC Med Educ 7:46. 2007
    ..We aimed to develop a course for post-graduate education which is clinically integrated and allows maximum flexibility for teachers and learners...
  9. ncbi Harmonising evidence-based medicine teaching: a study of the outcomes of e-learning in five European countries
    Regina Kulier
    The University of Birmingham, Edgbaston, Birmingham B15 2TG, UK
    BMC Med Educ 8:27. 2008
    ..We developed and evaluated the outcomes of an e-learning course for evidence based medicine (EBM) training in postgraduate medical education in different languages and settings across five European countries...
  10. ncbi Impact of short evidence summaries in discharge letters on adherence of practitioners to discharge medication. A cluster-randomised controlled trial
    R Kunz
    Basel Institute for Clinical Epidemiology, University Hospital Basel, Hebelstrasse 10, CH 4031 Basel, Switzerland
    Qual Saf Health Care 16:456-61. 2007
    ..International concern about quality of medical care has led to intensive study of interventions to ensure care is consistent with best evidence. Simple, inexpensive, feasible and effective interventions remain limited...
  11. ncbi [The GRADE System. An international approach to standardize the graduation of evidence and recommendations in guidelines]
    R Kunz
    Basel Institut für Klinische Epidemiologie, Universitatsspital Basel, Hebelstrasse 19, 4031, Basel, Switzerland
    Internist (Berl) 49:673-80. 2008
    ..Many guideline organizations and medical societies have endorsed the system and adopted it for their guideline processes...
  12. ncbi Misconceptions, challenges, uncertainty, and progress in guideline recommendations
    Regina Kunz
    Basel Institute of Clinical Epidemiology, University Hospital Basel, Basel, Switzerland
    Semin Hematol 45:167-75. 2008
    ..Many guideline organizations and medical societies have endorsed the system and adopted it for their guideline processes...
  13. ncbi How far did we get? How far to go? A European survey on postgraduate courses in evidence-based medicine
    Regina Kunz
    Basel Institute for Clinical Epidemiology BICE, University Hospital Basel, Basel, Switzerland
    J Eval Clin Pract 15:1196-204. 2009
    ..However, little is known about learning opportunities to acquire EBM-associated skills. The EUebm-Unity partnership explored current educational activities for EBM practice for doctors across Europe...
  14. ncbi Meta-analysis: effect of monotherapy and combination therapy with inhibitors of the renin angiotensin system on proteinuria in renal disease
    Regina Kunz
    Basel Institute for Clinical Epidemiology and Clinic for Transplantation Immunology and Nephrology, University Hospital Basel, Basel, Switzerland
    Ann Intern Med 148:30-48. 2008
    ..Reports suggest that angiotensin-receptor blockers (ARBs) reduce proteinuria, but results are variable. The relative effect of ARBs and angiotensin-converting enzyme (ACE) inhibitors, and their combined administration, remains uncertain...
  15. ncbi A systematic review finds that methodological quality is better than its reputation but can be improved in physiotherapy trials in childhood cerebral palsy
    Regina Kunz
    Basel Institute for Clinical Epidemiology, University Hospital of Basel, Hebelstrasse 10, 4031 Basel, Switzerland
    J Clin Epidemiol 59:1239-48. 2006
    ....
  16. ncbi [How many standards can variety take?]
    Regina Kunz
    Arbeitsgemeinschaft Koordinierungsausschuss, Auf dem Seidenberg 3a, 53721 Siegburg
    Z Arztl Fortbild Qualitatssich 97:291-4. 2003
    ..In this article, authors of the curriculum provide a replique to the criticisms...
  17. ncbi [Implementation of evidence-based medicine in clinical practice--external offers to search for and critically assess medical literature]
    Ulrike Euler
    , , Klinikum Charit,
    Z Arztl Fortbild Qualitatssich 96:325-31. 2002
    ..To achieve the latter evidence-based secondary literature and the development of evidence-based guidelines appear to be reasonable alternatives...
  18. ncbi [The implementation of evidence-based medicine in general practice-acceptance and use of external information services]
    Aaron Juche
    , Klinik I, Treuenbrietzen
    Z Arztl Fortbild Qualitatssich 100:383-7. 2006
    ..This is why it is important to develop some type of continuing medical education model that can be effectively integrated into everyday medical practice...
  19. ncbi Quality of reporting of randomized, controlled trials in cerebral palsy
    Heidi Anttila
    Finnish Office for Health Technology Assessment, National Research and Development Centre for Welfare and Health, Helsinki, Finland
    Pediatrics 117:2222-30. 2006
    ..Therefore, we set out to evaluate trial reporting by using the Consolidated Standards of Reporting Trials (CONSORT) statement recommendations...
  20. ncbi [Last but not least--the German Network EbM has got its glossary on EbM terms]
    Regina Kunz
    Gemeinsamer Bundesausschuss, Siegburg
    Z Arztl Fortbild Qualitatssich 98:429-35. 2004
    ..ebm-netzwerk.de/glossar.htm. The present glossary is just a start, though. Over the coming years more terms will have to be added according to the needs and suggestions of our readership. We thus call on active participation of its users...
  21. ncbi What is "quality of evidence" and why is it important to clinicians?
    Gordon H Guyatt
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada L8N 3Z5
    BMJ 336:995-8. 2008
  22. ncbi How strong is the evidence?
    Yngve Falck-Ytter
    Division of Gastroenterology, Case Western Reserve University, Louis Stokes Cleveland VA Medical Center and Case Medical Center, Cleveland, Ohio, USA
    Am J Gastroenterol 103:1334-8. 2008
  23. ncbi Integrating an evidence-based medicine rotation into an internal medicine residency program
    Elie A Akl
    Department of Medicine, University at Buffalo, ECMC-CC 142, 462 Grider St, Buffalo, NY 14215, USA
    Acad Med 79:897-904. 2004
    ..This multifaceted educational approach with an "on-the-ward" EBM resident, may improve the EBM knowledge and skills of targeted students and residents...
  24. ncbi An emerging consensus on grading recommendations?
    Gordon Guyatt
    McMaster University, Hamilton, Ontario, Canada
    Evid Based Med 11:2-4. 2006
  25. ncbi Five steps to conducting a systematic review
    Khalid S Khan
    Education Resource Centre, Birmingham Women's Hospital, Birmingham B15 2TG, UK
    J R Soc Med 96:118-21. 2003
  26. ncbi Incorporating considerations of resources use into grading recommendations
    Gordon H Guyatt
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada L8N 3Z5
    BMJ 336:1170-3. 2008
  27. ncbi Grading quality of evidence and strength of recommendations for diagnostic tests and strategies
    Holger J Schunemann
    Department of Epidemiology, Italian National Cancer Institute Regina Elena, 00144 Rome, Italy
    BMJ 336:1106-10. 2008
  28. ncbi The COOPERATE trial: a letter of concern
    Regina Kunz
    Lancet 371:1575-6. 2008
  29. ncbi Going from evidence to recommendations
    Gordon H Guyatt
    CLARITY Research Group, Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada L8N 3Z5
    BMJ 336:1049-51. 2008
  30. ncbi An emerging consensus on grading recommendations?
    Gordon Guyatt
    McMaster University, Hamilton, Ontario, Canada
    ACP J Club 144:A8-9. 2006
  31. ncbi Point: evidence-based medicine has a sound scientific base
    Paul J Karanicolas
    Chest 133:1067-71. 2008
  32. ncbi GRADE: an emerging consensus on rating quality of evidence and strength of recommendations
    Gordon H Guyatt
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada L8N 3Z5
    BMJ 336:924-6. 2008
  33. ncbi Which patients to include in the analysis?
    Regina Kunz
    Transfusion 46:881-4. 2006
  34. ncbi Evidence-based clinical practice guidelines for prostate cancer: the need for a unified approach
    Philipp Dahm
    Department of Urology, College of Medicine, University of Florida, Gainesville, Florida 32610 0247, USA
    Curr Opin Urol 17:200-7. 2007
    ..It further introduces the recommendations of the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) working group as a unified approach to guideline development...
  35. ncbi When small degrees of bias in randomized trials can mislead clinical decisions: an example of individualizing preventive treatment of upper gastrointestinal bleeding
    Regina Kunz
    Department of Internal Medicine, University Hospital Charite, Berlin, Germany
    Crit Care Med 30:1503-7. 2002
    ..The aim of this study is to assess under which circumstances clinicians need to be concerned about bias in clinical trials...