Meike Korner

Summary

Affiliation: University of Bern
Country: Switzerland

Publications

  1. doi request reprint GLP-2 receptors in human disease: high expression in gastrointestinal stromal tumors and Crohn's disease
    Meike Korner
    Division of Cell Biology and Experimental Cancer Research, Institute of Pathology, University of Berne, Berne, Switzerland
    Mol Cell Endocrinol 364:46-53. 2012
  2. pmc Alternative splicing of pre-mRNA in cancer: focus on G protein-coupled peptide hormone receptors
    Meike Korner
    Institute of Pathology of the University of Berne, Murtenstrasse 31, CH 3010 Berne, Switzerland
    Am J Pathol 175:461-72. 2009
  3. pmc CCK(2) receptor splice variant with intron 4 retention in human gastrointestinal and lung tumours
    Meike Korner
    Mayo Clinic, Cancer Center and Department of Molecular Pharmacology and Experimental Therapeutics, Scottsdale, Arizona, USA
    J Cell Mol Med 14:933-43. 2010
  4. ncbi request reprint Different proportions of aneusomic cells in ovarian inclusion cysts associated with serous borderline tumours and serous high-grade carcinomas support different pathogenetic pathways
    Meike Korner
    Institute of Pathology, University of Bern, Bern, Switzerland
    J Pathol 207:20-6. 2005
  5. ncbi request reprint Higher frequency of chromosomal aberrations in ovarian endometriosis compared to extragonadal endometriosis: A possible link to endometrioid adenocarcinoma
    Meike Korner
    Institute of Pathology, University of Bern, Bern, Switzerland
    Mod Pathol 19:1615-23. 2006
  6. ncbi request reprint Secretin receptors in the human liver: expression in biliary tract and cholangiocarcinoma, but not in hepatocytes or hepatocellular carcinoma
    Meike Korner
    Division of Cell Biology and Experimental Cancer Research, Institute of Pathology, University of Bern, Murtenstrasse 31, P O Box 62, CH 3010 Bern, Switzerland
    J Hepatol 45:825-35. 2006
  7. pmc Synthesis and in vitro characterization of radioiodinatable benzodiazepines selective for type 1 and type 2 cholecystokinin receptors
    Eyup Akgün
    Department of Molecular Pharmacology, Mayo Clinic, Scottsdale, Arizona 85259, USA
    J Med Chem 52:2138-47. 2009
  8. pmc Secretin receptors in normal and diseased human pancreas: marked reduction of receptor binding in ductal neoplasia
    Meike Korner
    Division of Cell Biology and Experimental Cancer Research, Institute of Pathology of the University of Bern, Murtenstrasse 31, PO Box 62, CH 3010 Bern, Switzerland
    Am J Pathol 167:959-68. 2005
  9. doi request reprint High expression of neuropeptide Y1 receptors in ewing sarcoma tumors
    Meike Korner
    Division of Cell Biology and Experimental Cancer Research, Institute of Pathology of the University of Berne, Murtenstrasse 31, Berne, Switzerland
    Clin Cancer Res 14:5043-9. 2008
  10. doi request reprint Neuropeptide Y receptors in primary human brain tumors: overexpression in high-grade tumors
    Meike Korner
    Division of Cell Biology and Experimental Cancer Research, Institute of Pathology of the University of Berne, Berne, Switzerland
    J Neuropathol Exp Neurol 67:741-9. 2008

Collaborators

Detail Information

Publications27

  1. doi request reprint GLP-2 receptors in human disease: high expression in gastrointestinal stromal tumors and Crohn's disease
    Meike Korner
    Division of Cell Biology and Experimental Cancer Research, Institute of Pathology, University of Berne, Berne, Switzerland
    Mol Cell Endocrinol 364:46-53. 2012
    ..Moreover, the over-expressed GLP-2 receptor in the myenteric plexus may represent the morphological correlate of the clinical target of teduglutide in Crohn's disease...
  2. pmc Alternative splicing of pre-mRNA in cancer: focus on G protein-coupled peptide hormone receptors
    Meike Korner
    Institute of Pathology of the University of Berne, Murtenstrasse 31, CH 3010 Berne, Switzerland
    Am J Pathol 175:461-72. 2009
    ....
  3. pmc CCK(2) receptor splice variant with intron 4 retention in human gastrointestinal and lung tumours
    Meike Korner
    Mayo Clinic, Cancer Center and Department of Molecular Pharmacology and Experimental Therapeutics, Scottsdale, Arizona, USA
    J Cell Mol Med 14:933-43. 2010
    ..In conclusion, the CCK(2)Ri4sv is a marker of specific gastrointestinal and lung tumours. With its high selectivity for and high incidence in SCLC and GIST, it may represent an attractive clinical target...
  4. ncbi request reprint Different proportions of aneusomic cells in ovarian inclusion cysts associated with serous borderline tumours and serous high-grade carcinomas support different pathogenetic pathways
    Meike Korner
    Institute of Pathology, University of Bern, Bern, Switzerland
    J Pathol 207:20-6. 2005
    ..Invasive high-grade serous carcinomas, by contrast, may arise from single cell clones subject to a different set of genetic events...
  5. ncbi request reprint Higher frequency of chromosomal aberrations in ovarian endometriosis compared to extragonadal endometriosis: A possible link to endometrioid adenocarcinoma
    Meike Korner
    Institute of Pathology, University of Bern, Bern, Switzerland
    Mod Pathol 19:1615-23. 2006
    ..The higher frequency of chromosomal aberrations in ovarian endometriosis than in extragonadal endometriosis suggests a role of the ovarian stromal milieu in the induction of genetic changes, which may eventually lead to invasive cancer...
  6. ncbi request reprint Secretin receptors in the human liver: expression in biliary tract and cholangiocarcinoma, but not in hepatocytes or hepatocellular carcinoma
    Meike Korner
    Division of Cell Biology and Experimental Cancer Research, Institute of Pathology, University of Bern, Murtenstrasse 31, P O Box 62, CH 3010 Bern, Switzerland
    J Hepatol 45:825-35. 2006
    ..The secretin receptor expression was investigated in the human liver because the liver is a physiological secretin target and because novel diagnostic and treatment modalities are needed for liver cancer...
  7. pmc Synthesis and in vitro characterization of radioiodinatable benzodiazepines selective for type 1 and type 2 cholecystokinin receptors
    Eyup Akgün
    Department of Molecular Pharmacology, Mayo Clinic, Scottsdale, Arizona 85259, USA
    J Med Chem 52:2138-47. 2009
    ..Moreover, it represents a suitable candidate to test antagonist binding to CCK(1) receptor-expressing tumors in vivo...
  8. pmc Secretin receptors in normal and diseased human pancreas: marked reduction of receptor binding in ductal neoplasia
    Meike Korner
    Division of Cell Biology and Experimental Cancer Research, Institute of Pathology of the University of Bern, Murtenstrasse 31, PO Box 62, CH 3010 Bern, Switzerland
    Am J Pathol 167:959-68. 2005
    ..Reduced secretin binding in pancreatic ductal tumors may relate to (alternatively spliced) secretin receptor isoforms. Thus, secretin receptors in pancreatic tumors may represent potential clinical targets...
  9. doi request reprint High expression of neuropeptide Y1 receptors in ewing sarcoma tumors
    Meike Korner
    Division of Cell Biology and Experimental Cancer Research, Institute of Pathology of the University of Berne, Murtenstrasse 31, Berne, Switzerland
    Clin Cancer Res 14:5043-9. 2008
    ..Because NPY receptors are expressed in selected sarcoma cell lines and because novel treatment options are needed for sarcomas, this study assessed the NPY receptor in primary human sarcomas...
  10. doi request reprint Neuropeptide Y receptors in primary human brain tumors: overexpression in high-grade tumors
    Meike Korner
    Division of Cell Biology and Experimental Cancer Research, Institute of Pathology of the University of Berne, Berne, Switzerland
    J Neuropathol Exp Neurol 67:741-9. 2008
    ..Moreover, identification of the high expression of NPY receptors in high-grade gliomas and embryonal brain tumors provides the basis for in vivo targeting...
  11. ncbi request reprint Value of immunohistochemistry for somatostatin receptor subtype sst2A in cancer tissues: lessons from the comparison of anti-sst2A antibodies with somatostatin receptor autoradiography
    Meike Korner
    Division of Cell Biology and Experimental Cancer Research, Institute of Pathology, University of Bern, Bern, Switzerland
    Am J Surg Pathol 29:1642-51. 2005
    ..In conclusion, the commercially available SS-800 antibody promises to be useful for the routine immunohistochemical assessment of sst2A in formalin-fixed human tumors...
  12. ncbi request reprint High expression of peptide receptors as a novel target in gastrointestinal stromal tumours
    Jean Claude Reubi
    Division of Cell Biology and Experimental Cancer Research, Institute of Pathology, University of Berne, Murtenstrasse 31, PO Box 62, 3010 Bern, Switzerland
    Eur J Nucl Med Mol Imaging 31:803-10. 2004
    ....
  13. ncbi request reprint High expression of neuropeptide y receptors in tumors of the human adrenal gland and extra-adrenal paraganglia
    Meike Korner
    Division of Cell Biology and Experimental Cancer Research, Institute of Pathology of the University of Bern, Bern, Switzerland
    Clin Cancer Res 10:8426-33. 2004
    ....
  14. ncbi request reprint Neuropeptide Y receptors in renal cell carcinomas and nephroblastomas
    Meike Korner
    Division of Cell Biology and Experimental Cancer Research, Institute of Pathology, University of Bern, Bern, Switzerland
    Int J Cancer 115:734-41. 2005
    ..With regard to clinical applications, NPY receptors may act as in vivo targets for receptor-directed therapy of RCCs and nephroblastomas for which alternative therapeutic approaches are still required...
  15. pmc Somatostatin receptor subtype 2A immunohistochemistry using a new monoclonal antibody selects tumors suitable for in vivo somatostatin receptor targeting
    Meike Korner
    Division of Cell Biology and Experimental Cancer Research, Institute of Pathology, University of Berne, Berne, Switzerland
    Am J Surg Pathol 36:242-52. 2012
    ..Under optimal methodological conditions, UMB-1 immunohistochemistry may be equivalent to in vitro receptor autoradiography...
  16. doi request reprint High expression of NPY receptors in the human testis
    Meike Korner
    Division of Cell Biology and Experimental Cancer Research, Institute of Pathology, University of Berne, Switzerland
    Mol Cell Endocrinol 337:62-70. 2011
    ..Based on its strong NPY receptor expression in Leydig cells and blood vessels, the normal human testis represents a potentially important physiological and pharmalogical NPY target...
  17. doi request reprint Early over-expression of GRP receptors in prostatic carcinogenesis
    Meike Korner
    Division of Cell Biology and Experimental Cancer Research, Institute of Pathology of the University of Berne, Berne, Switzerland
    Prostate 74:217-24. 2014
    ..This represents the molecular basis for GRP receptor imaging of prostate cancer with radioactive compounds. However, a focal, high density GRP receptor expression can be observed in hitherto uncharacterized prostate glands...
  18. ncbi request reprint Neuropeptide Y receptor expression in human primary ovarian neoplasms
    Meike Korner
    Division of Cell Biology and Experimental Cancer Research, Institute of Pathology, University of Bern, Bern, Switzerland
    Lab Invest 84:71-80. 2004
    ..Moreover, the high incidence and density of NPY receptors in sex cord-stromal tumors suggest that these receptors represent a new potential target for the diagnostic and therapeutic administration of NPY analogs in these tumors...
  19. pmc Phosphorylation of sst2 receptors in neuroendocrine tumors after octreotide treatment of patients
    Beatrice Waser
    Division of Cell Biology and Experimental Cancer Research, Institute of Pathology, University of Berne, Berne, Switzerland
    Am J Pathol 180:1942-9. 2012
    ....
  20. ncbi request reprint GLP-1 receptor expression in human tumors and human normal tissues: potential for in vivo targeting
    Meike Korner
    Division of Cell Biology and Experimental Cancer Research, Institute of Pathology, University of Bern, Bern, Switzerland
    J Nucl Med 48:736-43. 2007
    ..Anticipating a major development of GLP-1 receptor targeting in nuclear medicine, our aim was to evaluate in vitro the GLP-1 receptor expression in a large variety of other tumors and to compare it with that in nonneoplastic tissues...
  21. ncbi request reprint NPY receptors in human cancer: a review of current knowledge
    Meike Korner
    Division of Cell Biology and Experimental Cancer Research, Institute of Pathology, University of Bern, Murtenstrasse 31, PO Box 62, CH 3010 Bern, Switzerland
    Peptides 28:419-25. 2007
    ..Clinically, tumoral NPY receptors may be targeted with NPY analogs coupled with adequate radionuclides or cytotoxic agents for a scintigraphic tumor imaging and/or tumor therapy...
  22. doi request reprint A subset of metzincins and related genes constitutes a marker of human solid organ fibrosis
    Silke Rödder
    Department of Nephrology and Hypertension, Inselspital, University of Bern, Freiburgstrasse 15, 3010, Bern, Switzerland
    Virchows Arch 458:487-96. 2011
    ....
  23. pmc Glucagon-like peptide-1 receptor overexpression in cancer and its impact on clinical applications
    Meike Korner
    Division of Cell Biology and Experimental Research, Institute of Pathology, University of Berne Berne, Switzerland
    Front Endocrinol (Lausanne) 3:158. 2012
    ..While the functional role of GLP-1R in neoplasia is not known yet, it may be safe to monitor patients undergoing GLP-1 therapy carefully...
  24. ncbi request reprint Positive positron emission tomography scan in sarcoidosis and two challenging cases of metastatic cancer. CASE 3. Hoarseness caused by cancer metastasis to the vagus nerve
    Thomas Weber
    Division of General Thoracic Surgery, University Hospital Berne, Bern, Switzerland
    J Clin Oncol 23:8909-10. 2005
  25. pmc Increased placental phospholipid levels in pre-eclamptic pregnancies
    Xiao Huang
    Institute of Biochemistry and Molecular Medicine, University of Bern, Bern 3012, Switzerland
    Int J Mol Sci 14:3487-99. 2013
    ..These alterations could be a source of placental pathological changes in pre-eclampsia, such as lipid peroxide insult or dysregulation of lipid transport across the syncytiotrophoblast...
  26. ncbi request reprint Acute chest pain 16 days after coronary artery bypass surgery: an unusual cause
    Meike Korner
    Institute of Pathology, Kantonsspital Luzern, Luzern, Switzerland
    J Thorac Cardiovasc Surg 124:182-4. 2002
  27. doi request reprint Expression, localization, and functional model of cholesterol transporters in lactating and nonlactating mammary tissues of murine, bovine, and human origin
    Orlando Mani
    Institute of Biochemistry and Molecular Medicine, University of Bern, Bern, Switzerland
    Am J Physiol Regul Integr Comp Physiol 299:R642-54. 2010
    ..Because of the species-specific expression patterns of transporters in mammary tissue, mechanisms of cholesterol homeostasis seem to be differentially regulated between species...