T Koenig

Summary

Affiliation: University of Bern
Country: Switzerland

Publications

  1. ncbi A tutorial on data-driven methods for statistically assessing ERP topographies
    Thomas Koenig
    Department of Psychiatric Neurophysiology, University Hospital of Psychiatry, University of Bern, Bern, Switzerland
    Brain Topogr 27:72-83. 2014
  2. doi Is gamma band EEG synchronization reduced during auditory driving in schizophrenia patients with auditory verbal hallucinations?
    Thomas Koenig
    Department of Psychiatric Neurophysiology, University Hospital of Psychiatry, University of Bern, Switzerland
    Schizophr Res 141:266-70. 2012
  3. pmc Brain connectivity at different time-scales measured with EEG
    T Koenig
    Department of Psychiatric Neurophysiology, University Hospital of Clinical Psychiatry Bern, Bolligenstr 111, 3000 Bern 60, Switzerland
    Philos Trans R Soc Lond B Biol Sci 360:1015-23. 2005
  4. doi A method to determine the presence of averaged event-related fields using randomization tests
    Thomas Koenig
    Department of Psychiatric Neurophysiology, University Hospital of Psychiatry, University of Bern, Bern, Switzerland
    Brain Topogr 23:233-42. 2010
  5. ncbi A deviant EEG brain microstate in acute, neuroleptic-naive schizophrenics at rest
    T Koenig
    The KEY Institute for Brain Mind Research, University Hospital of Psychiatry, P O B 68, CH 8029 Zurich, Switzerland
    Eur Arch Psychiatry Clin Neurosci 249:205-11. 1999
  6. ncbi Establishing correlations of scalp field maps with other experimental variables using covariance analysis and resampling methods
    Thomas Koenig
    Department of Psychiatric Neurophysiology, University Hospital of Psychiatry, Bolligenstr 111, 3000 Bern 60, Switzerland
    Clin Neurophysiol 119:1262-70. 2008
  7. ncbi Decreased EEG synchronization in Alzheimer's disease and mild cognitive impairment
    T Koenig
    Department of Psychiatric Neurophysiology, University Hospital of Clinical Psychiatry, Bolligenstrasse 111, CH 3000 Berne 60, Switzerland
    Neurobiol Aging 26:165-71. 2005
  8. ncbi Decreased functional connectivity of EEG theta-frequency activity in first-episode, neuroleptic-naïve patients with schizophrenia: preliminary results
    T Koenig
    University Hospital of Clinical Psychiatry, Bolligenstr 111, CH 3000 Bern 60, Switzerland
    Schizophr Res 50:55-60. 2001
  9. pmc Ragu: a free tool for the analysis of EEG and MEG event-related scalp field data using global randomization statistics
    Thomas Koenig
    Department of Psychiatric Neurophysiology, University Hospital of Psychiatry Bern, University of Bern, 3000 Bern 60, Bolligenstr 111, Switzerland
    Comput Intell Neurosci 2011:938925. 2011
  10. ncbi Low resolution brain electromagnetic tomography (LORETA) functional imaging in acute, neuroleptic-naive, first-episode, productive schizophrenia
    R D Pascual-Marqui
    The KEY Institute for Brain Mind Research, University Hospital of Psychiatry, Zurich, Switzerland
    Psychiatry Res 90:169-79. 1999

Detail Information

Publications41

  1. ncbi A tutorial on data-driven methods for statistically assessing ERP topographies
    Thomas Koenig
    Department of Psychiatric Neurophysiology, University Hospital of Psychiatry, University of Bern, Bern, Switzerland
    Brain Topogr 27:72-83. 2014
    ..The increased statistical power allows identifying more subtle effects, which is particularly important in small and scarce patient populations. ..
  2. doi Is gamma band EEG synchronization reduced during auditory driving in schizophrenia patients with auditory verbal hallucinations?
    Thomas Koenig
    Department of Psychiatric Neurophysiology, University Hospital of Psychiatry, University of Bern, Switzerland
    Schizophr Res 141:266-70. 2012
    ..01). Our data suggests that normally, 40Hz stimulation leads to the activation of a synchronized network representing the sensory input, but in hallucinating patients, the same stimulation partly disrupts ongoing activity in this network...
  3. pmc Brain connectivity at different time-scales measured with EEG
    T Koenig
    Department of Psychiatric Neurophysiology, University Hospital of Clinical Psychiatry Bern, Bolligenstr 111, 3000 Bern 60, Switzerland
    Philos Trans R Soc Lond B Biol Sci 360:1015-23. 2005
    ..The findings are discussed in terms of short-lasting binding between different brain regions through synchronized oscillations, which could constitute a mechanism to form transient, functional neurocognitive networks...
  4. doi A method to determine the presence of averaged event-related fields using randomization tests
    Thomas Koenig
    Department of Psychiatric Neurophysiology, University Hospital of Psychiatry, University of Bern, Bern, Switzerland
    Brain Topogr 23:233-42. 2010
    ..Furthermore a series of measures to control for multiple testing are introduced and applied to the sample data...
  5. ncbi A deviant EEG brain microstate in acute, neuroleptic-naive schizophrenics at rest
    T Koenig
    The KEY Institute for Brain Mind Research, University Hospital of Psychiatry, P O B 68, CH 8029 Zurich, Switzerland
    Eur Arch Psychiatry Clin Neurosci 249:205-11. 1999
    ..Schizophrenic thinking apparently is not a continuous bias in brain functions, but consists of intermittent occurrences of inappropriate brain microstates that open access to inadequate processing strategies and context information..
  6. ncbi Establishing correlations of scalp field maps with other experimental variables using covariance analysis and resampling methods
    Thomas Koenig
    Department of Psychiatric Neurophysiology, University Hospital of Psychiatry, Bolligenstr 111, 3000 Bern 60, Switzerland
    Clin Neurophysiol 119:1262-70. 2008
    ..We introduce a procedure to identify spatially extended scalp fields that correlate with some external, continuous measure (reaction-time, performance, clinical status) and to test their significance...
  7. ncbi Decreased EEG synchronization in Alzheimer's disease and mild cognitive impairment
    T Koenig
    Department of Psychiatric Neurophysiology, University Hospital of Clinical Psychiatry, Bolligenstrasse 111, CH 3000 Berne 60, Switzerland
    Neurobiol Aging 26:165-71. 2005
    ..The results are discussed within the framework of current knowledge about the functional significance of the affected frequency bands...
  8. ncbi Decreased functional connectivity of EEG theta-frequency activity in first-episode, neuroleptic-naïve patients with schizophrenia: preliminary results
    T Koenig
    University Hospital of Clinical Psychiatry, Bolligenstr 111, CH 3000 Bern 60, Switzerland
    Schizophr Res 50:55-60. 2001
    ..Thus, our result suggests a loss of mutual interdependence of memory functions in patients with acute schizophrenia, which agrees well with previous reports of working memory dysfunction in schizophrenia...
  9. pmc Ragu: a free tool for the analysis of EEG and MEG event-related scalp field data using global randomization statistics
    Thomas Koenig
    Department of Psychiatric Neurophysiology, University Hospital of Psychiatry Bern, University of Bern, 3000 Bern 60, Bolligenstr 111, Switzerland
    Comput Intell Neurosci 2011:938925. 2011
    ..The aim of Ragu is to maximize statistical power while minimizing the need for a-priori choices of models and parameters (like inverse models or sensors of interest) that interact with and bias statistics...
  10. ncbi Low resolution brain electromagnetic tomography (LORETA) functional imaging in acute, neuroleptic-naive, first-episode, productive schizophrenia
    R D Pascual-Marqui
    The KEY Institute for Brain Mind Research, University Hospital of Psychiatry, Zurich, Switzerland
    Psychiatry Res 90:169-79. 1999
    ..Since all information processing is brain-state dependent, this dis-coordinated state must result in inadequate treatment of (externally or internally generated) information...
  11. ncbi Effects of weak mobile phone - electromagnetic fields (GSM, UMTS) on well-being and resting EEG
    H Kleinlogel
    Department of Psychiatric Neurophysiology, University Hospital of Psychiatry, University of Bern, Berne, Switzerland
    Bioelectromagnetics 29:479-87. 2008
    ..Neither the UMTS- nor the GSM-EMF produced any significant changes in the measured parameters compared to sham exposure. The results do not give any evidence for a deleterious effect of the EMF on normal healthy mobile phone users...
  12. doi Resting-state EEG in schizophrenia: auditory verbal hallucinations are related to shortening of specific microstates
    J Kindler
    University Hospital of Psychiatry and Psychotherapy, University of Bern, Switzerland
    Clin Neurophysiol 122:1179-82. 2011
    ..This shortening correlated with positive symptoms. We questioned if this reflected positive psychotic traits or present psychopathology...
  13. ncbi Event-related potential and EEG measures in Parkinson's disease without and with dementia
    H Tanaka
    The KEY Institute for Brain Mind Research, University Hospital of Psychiatry, Zurich, Switzerland
    Dement Geriatr Cogn Disord 11:39-45. 2000
    ..Prospective studies must determine whether P3 amplitude and EEG power in nondemented PD patients can serve as predictors of dementia...
  14. ncbi Event-related electric microstates of the brain differ between words with visual and abstract meaning
    T Koenig
    The KEY Institute for Brain Mind Research, University Hospital of Psychiatry, Zurich, Switzerland
    Electroencephalogr Clin Neurophysiol 106:535-46. 1998
    ....
  15. ncbi Brain electric correlates of strong belief in paranormal phenomena: intracerebral EEG source and regional Omega complexity analyses
    D Pizzagalli
    The KEY Institute for Brain Mind Research, University Hospital of Psychiatry, Zurich, Switzerland
    Psychiatry Res 100:139-54. 2000
    ..These markers may constitute the neurophysiological basis for paranormal and schizotypal ideation...
  16. ncbi Sex differences in semantic processing: event-related brain potentials distinguish between lower and higher order semantic analysis during word reading
    M Wirth
    University Hospital of Psychiatry, Bern, Switzerland
    Cereb Cortex 17:1987-97. 2007
    ..Taken together, the findings demonstrate that there is a selective sex difference in the controlled semantic analysis during passive word reading that is not reflected in different functional organization but in the depth of processing...
  17. ncbi Brain electric microstates and momentary conscious mind states as building blocks of spontaneous thinking: I. Visual imagery and abstract thoughts
    D Lehmann
    The KEY Institute for Brain Mind Research, University Hospital of Psychiatry, Zurich, Switzerland
    Int J Psychophysiol 29:1-11. 1998
    ..e. different classes (types) of thoughts (mentations); thus, the microstates might be candidates for the 'atoms of thought'...
  18. ncbi Event-related potential P300 microstate topography during visual one- and two-dimensional tasks in chronic schizophrenics
    K Kochi
    KEY Institute for Brain-Mind Research, University Hospital of Psychiatry, , Switzerland
    Eur Arch Psychiatry Clin Neurosci 246:288-96. 1996
    ..The lack of lateralization in the two-dimensional task supported the view that left-temporal abnormality in schizophrenics is only one of several task-dependent aberrations...
  19. ncbi Spatio-temporal dynamics of alpha brain electric fields, and cognitive modes
    D Lehmann
    KEY Institute for Brain Mind Research, University Hospital of Psychiatry, CH 8029 Zurich, Switzerland
    Int J Psychophysiol 26:99-112. 1997
    ..Different modes of spontaneous and induced mentation are associated with different brain electric microstates; these are proposed as candidates for psychophysiological 'atoms of thought'...
  20. doi Core networks for visual-concrete and abstract thought content: a brain electric microstate analysis
    Dietrich Lehmann
    The KEY Institute for Brain Mind Research, University Hospital of Psychiatry, University of Zurich, Lenggstrasse 31, Zurich, Switzerland
    Neuroimage 49:1073-9. 2010
    ..These core machineries of working memory thus are invariant to source or modality of input when treating the two types of information...
  21. ncbi BOLD correlates of EEG alpha phase-locking and the fMRI default mode network
    K Jann
    Department of Psychiatric Neurophysiology, University Hospital of Psychiatry, University of Bern, Bern, Switzerland
    Neuroimage 45:903-16. 2009
    ..Finally, we could localize specific areas where the GFS BOLD correlates and the associated RSN overlap. Thus, we claim that not only the spectral dynamics of EEG are important, but also their spatio-temporal organization...
  22. ncbi Competition for neuronal resources: how hallucinations make themselves heard
    Daniela Hubl
    University Hospital of Psychiatry, Department of Psychiatric Neurophysiology, Bolligenstrasse 111, CH 3000 Bern 60, Switzerland
    Br J Psychiatry 190:57-62. 2007
    ..Hallucinations are perceptions in the absence of a corresponding external sensory stimulus. However, during auditory verbal hallucinations, activation of the primary auditory cortex has been described...
  23. ncbi Pathways that make voices: white matter changes in auditory hallucinations
    Daniela Hubl
    Department of Psychiatric Neurophysiology, University Hospital of Clinical Psychiatry, Bern, Switzerland
    Arch Gen Psychiatry 61:658-68. 2004
    ..Magnetic resonance diffusion tensor imaging is a relatively new in vivo method to investigate the directionality of cortical white matter tracts...
  24. pmc Topographic electrophysiological signatures of FMRI Resting State Networks
    Kay Jann
    Department of Psychiatric Neurophysiology, University Hospital of Psychiatry and University of Bern, Bern, Switzerland
    PLoS ONE 5:e12945. 2010
    ..So far, only relationships between several EEG frequency bands and some RSNs could be demonstrated, but no study accounted for the spatial distribution of frequency domain EEG...
  25. ncbi Association of individual resting state EEG alpha frequency and cerebral blood flow
    Kay Jann
    Department of Psychiatric Neurophysiology, University Hospital of Psychiatry, University of Bern, Bolligenstrasse 111, 3000 Bern 60, Switzerland
    Neuroimage 51:365-72. 2010
    ....
  26. doi Structural analysis of Heschl's gyrus in schizophrenia patients with auditory hallucinations
    Daniela Hubl
    University Hospital of Psychiatry, Bern, Switzerland
    Neuropsychobiology 61:1-9. 2010
    ..The aim of the study was to analyze macrostructural features of HG in a group of patients reporting AVH who demonstrated white matter diffusion tensor imaging abnormalities reported previously...
  27. ncbi From EEG dependency multichannel matching pursuit to sparse topographic EEG decomposition
    Daniel Studer
    Department of Psychiatric Neurophysiology, University Hospital of Clinical Psychiatry, Bolligenstrasse 111, CH 3000 Berne, Switzerland
    J Neurosci Methods 153:261-75. 2006
    ..A clustering procedure applied to the topographies, the vectors of the corresponding contribution of an atom to the signal in each channel produced by DMMP, leads to an extremely sparse topographic decomposition of the EEG...
  28. doi Reduced frontal activation with increasing 2nd language proficiency
    Maria Stein
    University Hospital of Psychiatry, Department of Psychiatric Neurophysiology, Bolligenstrasse 111, CH 3000 Bern 60, Switzerland
    Neuropsychologia 47:2712-20. 2009
    ..Our results demonstrate that lexico-semantic processing of first and second language converges onto similar networks as second language proficiency increases...
  29. ncbi Native EEG and treatment effects in neuroleptic-naïve schizophrenic patients: time and frequency domain approaches
    Mitsuru Kikuchi
    Department of Psychiatric Neurophysiology, University Hospital of Psychiatry, University of Bern, Switzerland
    Schizophr Res 97:163-72. 2007
    ....
  30. ncbi Application and comparison of classification algorithms for recognition of Alzheimer's disease in electrical brain activity (EEG)
    Christoph Lehmann
    University Hospital of Clinical Psychiatry, Department of Psychiatric Neurophysiology, University of Berne, Bolligenstrasse 111, CH 3000 Bern 60, Switzerland
    J Neurosci Methods 161:342-50. 2007
    ..controls, using SVM and neural networks, values of 89% and 88% for sensitivity and specificity were achieved. Such a remarkable performance proves the value of these classification algorithms for clinical diagnostics...
  31. doi Localizing seizure-onset zones in presurgical evaluation of drug-resistant epilepsy by electroencephalography/fMRI: effectiveness of alternative thresholding strategies
    M Hauf
    Support Center of Advanced Neuroimaging, Inselspital, University of Bern, Switzerland
    AJNR Am J Neuroradiol 33:1818-24. 2012
    ..In this study, we evaluated different thresholding strategies in EEG/fMRI for the assessment of hemodynamic responses to IEDs in the SOZ of drug-resistant epilepsy...
  32. ncbi Effects of weak mobile phone - electromagnetic fields (GSM, UMTS) on event related potentials and cognitive functions
    H Kleinlogel
    Department of Psychiatric Neurophysiology, University Hospital of Psychiatry, University of Bern, Berne, Switzerland
    Bioelectromagnetics 29:488-97. 2008
    ..Neither the UMTS- nor the GSM-EMF produced any significant changes in the measured parameters compared to sham exposure. The results do not give any evidence for a deleterious effect of the EMF on normal healthy mobile phone users...
  33. ncbi Plasticity in the adult language system: a longitudinal electrophysiological study on second language learning
    M Stein
    Department of Psychiatric Neurophysiology, University Hospital of Psychiatry, Bolligenstrasse 111, CH 3000, Bern 60, Switzerland
    Neuroimage 33:774-83. 2006
    ..Thus, our results suggest that the reduced IFG activation found in previous fMRI studies might not reflect a generally lower activation but rather a shorter duration of activity...
  34. doi ERP correlates of superordinate category activation
    Rahel Schumacher
    Department of Psychology, University of Bern, Switzerland
    Int J Psychophysiol 72:134-44. 2009
    ..The paradigm seems to be suitable for further examination of superordinate activation processes and evaluation of impairments such as thought disorders in schizophrenic patients...
  35. doi The early context effect reflects activity in the temporo-prefrontal semantic system: evidence from electrical neuroimaging of abstract and concrete word reading
    Miranka Wirth
    University Hospital of Psychiatry, Bern, Switzerland
    Neuroimage 42:423-36. 2008
    ..Taken together our findings show that the early context effect reflects activation processes in verbal semantic memory...
  36. ncbi EEG microstate duration and syntax in acute, medication-naive, first-episode schizophrenia: a multi-center study
    Dietrich Lehmann
    The KEY Institute for Brain Mind Research, University Hospital of Psychiatry, CH 8029 Zurich, Switzerland
    Psychiatry Res 138:141-56. 2005
    ..The intermittent occurrence might account for Bleuler's "double bookkeeping." The disturbed microstate syntax opens a novel physiological comparison of mental operations between patients and controls...
  37. ncbi BOLD correlates of continuously fluctuating epileptic activity isolated by independent component analysis
    Kay Jann
    Department of Psychiatric Neurophysiology, University Hospital of Psychiatry, University of Bern, Bern, Switzerland
    Neuroimage 42:635-48. 2008
    ....
  38. ncbi Professional musicians listen differently to music
    C A Mikutta
    University Hospital of Psychiatry, University of Bern, Switzerland Department of Psychology, Helen Wills Neuroscience Institute, University of California, Berkeley, CA, USA Electronic address
    Neuroscience 268:102-11. 2014
    ..Discussion: Professionals exhibited different and/or more intense patterns of emotional activation when they listened to the music. The results of the present study underscore the impact of music experience on emotional reactions. ..
  39. ncbi A pharmaco-EEG study on antipsychotic drugs in healthy volunteers
    Masafumi Yoshimura
    Department of Psychiatric Neurophysiology, University Hospital of Psychiatry, Bern, Switzerland
    Psychopharmacology (Berl) 191:995-1004. 2007
    ..Previous studies found that some psychotropic drugs had EEG effects opposite to the EEG effects of the mental disorders treated with these drugs (key-lock principle)...
  40. ncbi Millisecond by millisecond, year by year: normative EEG microstates and developmental stages
    Thomas Koenig
    Department of Psychiatric Neurophysiology, University Hospital of Clinical Psychiatry, Bern, Switzerland, USA
    Neuroimage 16:41-8. 2002
    ....
  41. ncbi Hemispheric lateralization patterns and psychotic experiences in healthy subjects
    Armida Mucci
    Department of Psychiatry, University of Naples SUN, Largo Madonna delle Grazie, 80138 Naples, Italy
    Psychiatry Res 139:141-54. 2005
    ..Our results demonstrated gender-related differences in the pattern of hemispheric imbalance associated with psychotic experiences in healthy subjects...