Research Topics
| Yvonne KesslerSummaryAffiliation: University of Zurich Country: Switzerland Publications
| Collaborators
|
Detail Information
Publications
Chronic "Candidatus Mycoplasma turicensis" infectionMarilisa Novacco
Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, 8057 Zurich, Switzerland
Vet Res 42:59. 2011..Our results enhance the knowledge of "Candidatus M. turicensis" infection pathogenesis and are clinically relevant to the prognosis of hemoplasma-infected cats...- Dominance of highly divergent feline leukemia virus A progeny variants in a cat with recurrent viremia and fatal lymphomaA Katrin Helfer-Hungerbuehler
Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland
Retrovirology 7:14. 2010..5 years after the initial experimental exposure to FeLV-A/Glasgow-1. The goals of the present study were to investigate this FeLV reoccurrence and molecularly characterize the progeny viruses... - Quantitative TaqMan real-time PCR assays for gene expression normalisation in feline tissuesYvonne Kessler
University of Zurich, Switzerland
BMC Mol Biol 10:106. 2009.... 
How molecular methods change our views of FeLV infection and vaccinationRegina Hofmann-Lehmann
Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Winterthurerstr 260, CH 8057 Zurich, Switzerland
Vet Immunol Immunopathol 123:119-23. 2008..The use of sensitive molecular methods will contribute to a more in-depth understanding of the FeLV pathogenesis...- Development and application of a universal Hemoplasma screening assay based on the SYBR green PCR principleBarbara Willi
Clinical Laboratory, University of Zurich, Winterthurerstrasse 260, 8057 Zurich, Switzerland
J Clin Microbiol 47:4049-54. 2009..The SYBR green PCR assay described here is a suitable tool to screen for known and so-far-undiscovered hemoplasma species. Positive results should be confirmed by specific TaqMan PCR or sequencing... 
Real-time PCR-based prevalence study, infection follow-up and molecular characterization of canine hemotropic mycoplasmasNicole Wengi
Department for Farm Animals, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, 8057 Zurich, Switzerland
Vet Microbiol 126:132-41. 2008..sanguineus. Nonetheless, veterinarians may expect hemoplasma infections in dogs with a travel history and/or after potential tick vector exposure...- Reassessment of feline leukaemia virus (FeLV) vaccines with novel sensitive molecular assaysRegina Hofmann-Lehmann
Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Winterthurerstr 260, CH 8057 Zurich, Switzerland
Vaccine 24:1087-94. 2006..The loads were significantly associated with the infection outcome. Thus, commonly used FeLV vaccines understood to be successful model antiretroviral vaccines protecting against FeLV-related diseases do not confer sterilizing immunity... - Real-time PCR investigation of feline leukemia virus proviral and viral RNA loads in leukocyte subsetsValentino Cattori
Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Winterthurerstreet 260, CH 8057 Zurich, Switzerland
Vet Immunol Immunopathol 123:124-8. 2008..These results indicate that FeLV persistent viremia is associated with secondary viremia of bone marrow origin, whereas regressive cats only sustain a non-productive infection in low numbers of lymphocytes... - Association between endogenous feline leukemia virus loads and exogenous feline leukemia virus infection in domestic catsRavi Tandon
Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, 8057 Zurich, Switzerland
Virus Res 135:136-43. 2008..In conclusion, our results demonstrated an association between enFeLV loads and FeLV replication but not outcome of infection. enFeLV should be considered as an important confounder in experimental FeLV infection or vaccination studies... - Vaccination against the feline leukaemia virus: outcome and response categories and long-term follow-upRegina Hofmann-Lehmann
Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Winterthurerstr 260, CH 8057 Zurich, Switzerland
Vaccine 25:5531-9. 2007..Persistence of plasma viral RNA was moderately associated with reactivation of FeLV infection. In conclusion, sensitive molecular assays are important tools for reviewing pathogenesis of FeLV infection... - Phylogenetic analysis of "Candidatus Mycoplasma turicensis" isolates from pet cats in the United Kingdom, Australia, and South Africa, with analysis of risk factors for infectionBarbara Willi
Clinical Laboratory, Vetsuisse-Faculty, University of Zurich, Winterthurerstrasse 260, 8057 Zurich, Switzerland, and Bryanston Veterinary Hospital, South Africa
J Clin Microbiol 44:4430-5. 2006..In summary, "Candidatus Mycoplasma turicensis" infection in pet cats exists over a wide geographical area and significantly decreased PCV values are observed in cats coinfected with other feline hemoplasmas... - Concurrent infections with vector-borne pathogens associated with fatal hemolytic anemia in a cattle herd in SwitzerlandRegina Hofmann-Lehmann
Clinical Laboratory, University of Zurich, Switzerland
J Clin Microbiol 42:3775-80. 2004..It remains to be seen whether similar disease outbreaks will have to be anticipated in northern Europe in the future... - Cellular segregation of feline leukemia provirus and viral RNA in leukocyte subsets of long-term experimentally infected catsAndrea C Pepin
Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Switzerland
Virus Res 127:9-16. 2007..The herein described methods are important prerequisites to gain a deeper insight into the pathogenesis of FeLV infection... - Identification, molecular characterization, and occurrence of two bovine hemoplasma species in Swiss cattle and development of real-time TaqMan quantitative PCR assays for diagnosis of bovine hemoplasma infectionsMarina L Meli
Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland
J Clin Microbiol 48:3563-8. 2010..wenyonii and exhibited higher M. wenyonii blood loads than animals with unrelated diseases and healthy animals. Coinfections may increase the pathogenicity and clinical significance of bovine hemoplasmosis... - Quantification of endogenous and exogenous feline leukemia virus sequences by real-time PCR assaysRavi Tandon
Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, 8057 Zurich, Switzerland
Vet Immunol Immunopathol 123:129-33. 2008..In conclusion, the quantitative real-time PCR assays described herein are important prerequisites to quantify enFeLV proviral loads in felids and thus are important tools to investigate the role of enFeLV loads in FeLV infection... - Prevalence, risk factor analysis, and follow-up of infections caused by three feline hemoplasma species in cats in SwitzerlandBarbara Willi
Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, 8057 Zurich, Switzerland
J Clin Microbiol 44:961-9. 2006.... - From Haemobartonella to hemoplasma: molecular methods provide new insightsBarbara Willi
Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, 8057, Zurich, Switzerland
Vet Microbiol 125:197-209. 2007..Based on a potential vector-borne and interspecies transmission, a zoonotic potential of hemoplasmas should be further investigated... - Absolute quantitation of feline leukemia virus proviral DNA and viral RNA loads by TaqMan real-time PCR and RT-PCRValentino Cattori
Clinical Laboratory, University of Zeurich, Winterthurerstrasse, Zurick, Switzerland
Methods Mol Biol 429:73-87. 2008..cRNA is synthesized from the linearized plasmid DNA. Standard DNA and RNA are quantified, diluted and used to determine efficiency, sensitivity, linear amplification range, and precision of the quantitative TaqMan real-time PCR assays... - Exposure of cats to low doses of FeLV: seroconversion as the sole parameter of infectionAndrea Major
Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, 8057, Zurich, Switzerland
Vet Res 41:17. 2010..Therefore, commonly used detection methods do not detect all FeLV-infected animals, possibly leading to an underestimation of the prevalence of infection... - Copy number polymorphism of endogenous feline leukemia virus-like sequencesRavi Tandon
Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, CH 8057 Zurich, Switzerland
Mol Cell Probes 21:257-66. 2007..The assays described herein are important prerequisites to quantify enFeLV loads and thus to investigate the influence of enFeLV loads on the course of FeLV infection... - Worldwide occurrence of feline hemoplasma infections in wild felid speciesBarbara Willi
Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, 8057 Zurich, Switzerland
J Clin Microbiol 45:1159-66. 2007..In conclusion, 9 out of 15 wild felid species from three different continents were found to be infected with feline hemoplasmas. The effect of feline hemoplasma infections on wild felid populations needs to be further investigated... - The kinetics of feline leukaemia virus shedding in experimentally infected cats are associated with infection outcomeValentino Cattori
Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland
Vet Microbiol 133:292-6. 2009..To determine the clinically relevant outcome of FeLV infection in exposed cats, however, p27 antigen levels in the peripheral blood should be measured... - Feline leukemia virus infection: a threat for the survival of the critically endangered Iberian lynx (Lynx pardinus)Marina L Meli
Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, CH 8057 Zurich, Switzerland
Vet Immunol Immunopathol 134:61-7. 2010..It could result in epidemics that have the potential to eradicate the entire lynx population... - Antibody induction after combined application of an adjuvanted recombinant FeLV vaccine and a multivalent modified live virus vaccine with a chlamydial componentChantal Brunner
Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, CH 8057 Zurich, Switzerland
Vaccine 24:1838-46. 2006..felis but diminished for FPV. The use of these vaccines in combination was safe and will simplify vaccination schedules in veterinary practice... - Molecular Investigations of Rickettsia helvetica infection in dogs, foxes, humans, and Ixodes ticksFelicitas S Boretti
Clinic for Small Animal Internal Medicine, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, 8057 Zurich, Switzerland
Appl Environ Microbiol 75:3230-7. 2009..e., R. helvetica was 13 times more frequent in unfed ticks than the tick-borne encephalitis virus), many mammals may be exposed to R. helvetica. The PCR assay described here represents an important tool for studying this topic... - Real-time PCR investigation of potential vectors, reservoirs, and shedding patterns of feline hemotropic mycoplasmasBarbara Willi
Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, 8057 Zurich, Switzerland
Appl Environ Microbiol 73:3798-802. 2007..Neither the investigated tick nor the rodent population seems to represent a major reservoir for feline hemotropic mycoplasmas in Switzerland... - Identification, characterization, and application of a recombinant antigen for the serological investigation of feline hemotropic Mycoplasma infectionsGodelind A Wolf-Jäckel
Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, 8057 Zurich, Switzerland
Clin Vaccine Immunol 17:1917-25. 2010..This is the first description of a full-length purified recombinant feline hemoplasma antigen that can readily be applied in future pathogenesis studies and may have potential for application in a diagnostic serological test... - Importance of canine distemper virus (CDV) infection in free-ranging Iberian lynxes (Lynx pardinus)Marina L Meli
Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, CH 8057 Zurich, Switzerland
Vet Microbiol 146:132-7. 2010..To reduce the infectious pressure of CDV on this endangered population, a mass dog vaccination should be considered... - Quantitation of feline leukaemia virus viral and proviral loads by TaqMan real-time polymerase chain reactionRavi Tandon
Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, CH-8057 Zurich, Switzerland
J Virol Methods 130:124-32. 2005..Thus, for most effective detection of FeLV exposure and characterization of the infection in a cat, PCR assays are recommended as diagnostic tools... - In vitro inhibition of feline leukaemia virus infection by synthetic peptides derived from the transmembrane domainEva Boenzli
Clinical Laboratory, Faculty of Veterinary Medicine, University of Zurich, Zurich, Switzerland
Antivir Ther 16:905-13. 2011..We identified and synthetically produced 11 FeLV peptides and evaluated their potential to block FeLV infection in vitro... - Rapid detection of feline leukemia virus provirus integration into feline genomic DNAValentino Cattori
Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, CH 8057 Zurich, Switzerland
Mol Cell Probes 20:172-81. 2006.... - Prevalence and geographical distribution of canine hemotropic mycoplasma infections in Mediterranean countries and analysis of risk factors for infectionMarilisa Novacco
Vetsuisse Faculty, University of Zurich, Zurich, Switzerland
Vet Microbiol 142:276-84. 2010..The climate and living conditions seemed to influence canine hemoplasma prevalence. The clinical importance of canine hemoplasma infections appeared to be low, but the infection stage of the presented dogs was unknown... - Thyroid enlargement and its relationship to clinicopathological parameters and T(4) status in suspected hyperthyroid catsFelicitas S Boretti
Clinic for Small Animal Internal Medicine, Vetsuisse Faculty, University of Zurich, Winterthurerstr 260, CH 8057 Zurich, Switzerland
J Feline Med Surg 11:286-92. 2009..Our study demonstrates that although no reliable conclusion on the functional status of the thyroid can be drawn based on its size the likelihood of hyperthyroidism increases with increasing size of the gland... - Feline leukemia virus and other pathogens as important threats to the survival of the critically endangered Iberian lynx (Lynx pardinus)Marina L Meli
Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland
PLoS ONE 4:e4744. 2009..In this context, a retrospective survey on prevalence of selected feline pathogens in free-ranging lynxes was initiated... - Haemotrophic Mycoplasma infection in horsesSarah M Dieckmann
Institute of Veterinary Bacteriology, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 270, Zurich, Switzerland
Vet Microbiol 145:351-3. 2010..Using a HM specific PCR assay and subsequent sequencing the infective agents isolated from the blood of said horses were confirmed as closely related to the HM species Mycoplasma haemofelis and 'Candidatus Mycoplasma haemobos'... - Evaluation of recombinant human thyroid-stimulating hormone to test thyroid function in dogs suspected of having hypothyroidismFelicitas S Boretti
Clinic for Small Animal Internal Medicine, Vetsuisse Faculty, University of Zurich, 8057 Zurich, Switzerland
Am J Vet Res 67:2012-6. 2006.... - Babesiosis in free-ranging chamois (Rupicapra r. rupicapra) from SwitzerlandStefan Hoby
Centre for Fish and Wildlife Health, Institute of Animal Pathology, Vetsuisse Faculty, University of Berne, Langgassstrasse 122, 3001 Bern, Switzerland
Vet Parasitol 148:341-5. 2007..This is the first report of fatal Babesia infections in chamois raising the question of an emerging disease in this species... - Development and application of a real-time TaqMan(®) qPCR assay for detection and quantification of 'Candidatus Mycoplasma haemolamae' in South American camelidsMarina L Meli
Clinical Laboratory, Vetsuisse Faculty, University of Zurich, CH 8057 Zurich, Switzerland
Vet Microbiol 146:290-4. 2010..haemolamae' and may be used in future studies to investigate the prevalence, pathogenesis and treatment follow-up of hemoplasma infections in South American camelids... - Identification, molecular characterization, and experimental transmission of a new hemoplasma isolate from a cat with hemolytic anemia in SwitzerlandBarbara Willi
Clinical Laboratory, Vetsuisse-Faculty, University of Zurich, Winterthurerstrasse 260, 8057 Zurich, Switzerland
J Clin Microbiol 43:2581-5. 2005..coccoides and M. haemomuris. A quantitative real-time PCR assay specific for this newly discovered agent was developed, which will be a prerequisite for the diagnosis of infections with the new hemoplasma isolate... - In vivo transmission studies of 'Candidatus Mycoplasma turicensis' in the domestic catKristina Museux
Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Switzerland
Vet Res 40:45. 2009..In conclusion, CMt transmission by social contact seems less likely than transmission by aggressive interaction. The latter transmission may occur if the recipient cat is exposed to blood from an infected cat... - The innate antiviral immune system of the cat: molecular tools for the measurement of its state of activationCéline Robert-Tissot
Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Winterthurerstr 260, CH 8057 Zurich, Switzerland
Vet Immunol Immunopathol 143:269-81. 2011.... - Seroprevalence of selected infectious agents in a free-ranging, low-density lion population in the Central Kalahari Game Reserves in BotswanaSandra Ramsauer
Zoological Institute, Zurich University, CH 8057 Zurich, Switzerland
Clin Vaccine Immunol 14:808-10. 2007..4%). Canine distemper virus and feline calicivirus occurred with a low prevalence. All individuals tested negative for feline coronavirus, feline parvovirus, feline leukemia virus, Ehrlichia canis, and Anaplasma phagocytophilum... - Feline coronavirus serotypes 1 and 2: seroprevalence and association with disease in SwitzerlandMaya Kummrow
Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, , Switzerland
Clin Diagn Lab Immunol 12:1209-15. 2005..When serology is used in addition to clinical signs, hematology, and clinical chemistry results as an aid to diagnose clinical FIP, TGEV shows a diagnostic efficiency equal to that of a FCoV antigen... - Evaluation of the Mythic 18 hematology analyzer for use with canine, feline, and equine samplesAndrea K Wassmuth
Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, 8057 Zurich, Switzerland
J Vet Diagn Invest 23:436-53. 2011..As with all impedance-based hematological instruments, evaluation of a blood smear is absolutely indicated to check for the presence of platelet aggregates, to verify WBC differentiation, and to identify possible abnormalities... - First morphological characterization of 'Candidatus Mycoplasma turicensis' using electron microscopyBarbara Willi
Clinical Laboratory, University of Zurich, Zurich, Switzerland
Vet Microbiol 149:367-73. 2011..This is the first study to provide morphological evidence of CMt thereby confirming its status as a distinct haemoplasma species, and to present electron microscopic features of CMhm... - Comparison of the biological activity of recombinant human thyroid-stimulating hormone with bovine thyroid-stimulating hormone and evaluation of recombinant human thyroid-stimulating hormone in healthy dogs of different breedsFelicitas S Boretti
Clinic for Small Animal Internal Medicine, Vetsuisse Faculty, University of Zurich, Switzerland
Am J Vet Res 67:1169-72. 2006..Euthyroidism was confirmed if post-TSH simulation T(4) concentration was > or = 2.5 microg/dL and at least 1.5 times basal T(4) concentration... - Quantification and molecular characterization of the feline leukemia virus A receptorA Katrin Helfer-Hungerbuehler
Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland
Infect Genet Evol 11:1940-50. 2011..The differential susceptibility of different species to FeLV could not be attributed to variations in the fTHTR1 sequence... - Performance evaluation of the Sysmex pocH-100iV Diff hematology analyzer for analysis of canine, feline, equine, and bovine bloodBarbara Riond
Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland
Vet Clin Pathol 40:484-95. 2011..The Sysmex pocH-100iV Diff is an impedance hematology analyzer recently introduced for point-of-care use in veterinary practices in Europe... - Serum protein concentrations from clinically healthy horses determined by agarose gel electrophoresisBarbara Riond
Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland
Vet Clin Pathol 38:73-7. 2009..Reference values for horses using agarose gel as a support medium have not been reported... - Seroprevalence of anaplasmosis among cattle in Switzerland in 1998 and 2003: no evidence of an emerging diseaseUte M Dreher
Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, CH-8057 Zurich, Switzerland
Vet Microbiol 107:71-9. 2005..This reaction is in accordance with A. marginale or a cross reacting agent such as Anaplasma ovis. From our results we conclude that the hypothesis of an increased prevalence of anaplasmosis in cattle in Switzerland must be rejected... - RNase P RNA gene (rnpB) phylogeny of Hemoplasmas and other Mycoplasma speciesIain R Peters
School of Clinical Veterinary Science, University of Bristol, North Somerset, United Kingdom
J Clin Microbiol 46:1873-7. 2008..Phylogenetic analysis of these sequences showed that all hemoplasmas were present within a single clade and were most closely related to Mycoplasma fastidiosum, similar to the results found with 16S rRNA gene phylogeny... - Convergent evolution of SIV env after independent inoculation of rhesus macaques with infectious proviral DNAKathleen A Buckley
Department of Cancer Immunology and AIDS, Dana-Farber Cancer Institute, 44 Binney Street, JFB-809, Boston, MA 02115, USA
Virology 312:470-80. 2003..Together, these data indicate that the env genes of SIVmac239, SIVdelta3, and SIVdelta3+, in the context of different proviral backbones, evolve similarly in different hosts during disease progression... - The prevalence of three species of feline haemoplasmas in samples submitted to a diagnostics service as determined by three novel real-time duplex PCR assaysIain R Peters
School of Clinical Veterinary Science, University of Bristol, Langford House, Langford, Bristol BS40 5DU, UK
Vet Microbiol 126:142-50. 2008..CMhm was the most common infection and CMt infections were often associated with co-infection with other haemoplasma species, especially CMhm... - 2008 American Association of Feline Practitioners' feline retrovirus management guidelinesJulie Levy
Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610, USA
J Feline Med Surg 10:300-16. 2008..More research is needed to identify best practices to improve long-term outcomes following retroviral infections in cats... - Fat intake modifies vascular responsiveness and receptor expression of vasoconstrictors: implications for diet-induced obesityAlexa L Mundy
Department of Medicine, Internal Medicine I, Medical Policlinic, University Hospital Zurich, Ramistrasse 100, CH 8091 Zurich, Switzerland
Cardiovasc Res 73:368-75. 2007..The aim of this study was to investigate the effects of dietary fat content on vasoreactivity and receptor expression at the level of gene and protein expression... - Epizootiologic investigations of selected infectious disease agents in free-ranging Eurasian lynx from SwedenMarie Pierre Ryser-Degiorgis
Department of Wildlife, National Veterinary Institute, SE 751 89 Uppsala, Sweden
J Wildl Dis 41:58-66. 2005..phagocytophila in four lynx, all serology was negative. All PCR results also were negative. It was concluded that free-ranging Swedish lynx do not have frequent contact with the infectious agents considered in this study... - Coinfection with Schistosoma mansoni reactivates viremia in rhesus macaques with chronic simian-human immunodeficiency virus clade C infectionMila Ayash Rashkovsky
Dana Farber Cancer Institute, 44 Binney Street, Boston, MA 02115 6084, USA
Infect Immun 75:1751-6. 2007..05). Thus, S. mansoni coinfection significantly increased viral replication and induced T-cell subset alterations in monkeys with chronic SHIV clade C infection... - Genetic diversity of anaplasma species major surface proteins and implications for anaplasmosis serodiagnosis and vaccine developmentJose De La Fuente
Department of Veterinary Pathobiology, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, OK 74078 2007, USA
Anim Health Res Rev 6:75-89. 2005..Information concerning the genetic diversity of Anaplasma spp. MSPs will likely influence the development of serodiagnostic assays and vaccine strategies for the control of anaplasmosis... - Genome organization and reverse genetic analysis of a type I feline coronavirusGergely Tekes
Kantonal Hospital St Gallen, Research Department, 9007 St Gallen, Switzerland
J Virol 82:1851-9. 2008..Thus, our established reverse genetic system provides a suitable tool to study the molecular biology of serotype I FCoV... - Combined effect of zidovudine (ZDV), lamivudine (3TC) and abacavir (ABC) antiretroviral therapy in suppressing in vitro FIV replicationLeslie R Bisset
Swiss National Center for Retroviruses, , Gloriastrasse 30, CH-8028, , Switzerland
Antiviral Res 53:35-45. 2002..However, in contrast to its effect on HIV replication, the ribonucleotide reductase inhibitor hydroxyurea (HU) is unable to effectively control in vitro FIV replication... - Quantitation of simian cytokine and beta-chemokine mRNAs, using real-time reverse transcriptase-polymerase chain reaction: variations in expression during chronic primate lentivirus infectionRegina Hofmann-Lehmann
Dana Farber Cancer Institute and Department of Medicine, Harvard Medical School, Boston, Massachusetts 02115, USA
AIDS Res Hum Retroviruses 18:627-39. 2002..The newly established quantitative real-time RT-PCR assays will allow the determination of cytokine and beta-chemokine patterns in rhesus macaques in studies of microbial pathogenesis or vaccine development... - Live attenuated, nef-deleted SIV is pathogenic in most adult macaques after prolonged observationRegina Hofmann-Lehmann
Department of Cancer Immunology and AIDS, Dana-Farber Cancer Institute, Department of Medicine, Harvard Medical School, Boston, Massachusetts 02115, USA
AIDS 17:157-66. 2003..Thus, mass vaccination of humans with similarly constructed live attenuated HIV vaccines, recently suggested for countries with high HIV-1 transmission rates, seems contraindicated... - Older rhesus macaque infants are more susceptible to oral infection with simian-human immunodeficiency virus 89.6P than neonatesAgnes Laurence Chenine
Department of Cancer Immunology, Dana Farber Cancer Institute, 44 Binney Street, JFB809, Boston, MA 02115 6084, USA
J Virol 79:1333-6. 2005..Thus, route of inoculation and age are important determinants of SHIV89.6P infectivity in rhesus macaques... - First evidence of feline herpesvirus, calicivirus, parvovirus, and Ehrlichia exposure in Brazilian free-ranging felidsClaudia Filoni
Departamento de Patologia, Faculdade de Medicina Veterinaria e Zootecnia, Universidade de Sã o Paulo, Avenida Prof Dr Orlando Marques de Paiva 87, 05508 270, Sao Paulo, SP, Brazil
J Wildl Dis 42:470-7. 2006..Antibodies to FHV 1, FCV, FCoV, FPV, FeLV, FIV, PLV or related viruses, and to B. henselae were detected. Furthermore, high-titered antibodies to E. canis or a closely related agent were detected in a puma for the first time... - Time dependence of protective post-exposure prophylaxis with human monoclonal antibodies against pathogenic SHIV challenge in newborn macaquesFlavia Ferrantelli
Department of Cancer Immunology and AIDS, Dana Farber Cancer Institute, Boston, MA 02115, USA
Virology 358:69-78. 2007..Taken together with our results from other PEP studies, these data show that the success of passive immunization depends on the nmAb potency/dose and the time window between virus exposure and start of immunotherapy...