W L Kelley

Summary

Affiliation: University of Geneva
Country: Switzerland

Publications

  1. pmc The T/t common exon of simian virus 40, JC, and BK polyomavirus T antigens can functionally replace the J-domain of the Escherichia coli DnaJ molecular chaperone
    W L Kelley
    Departement de Biochimie Medicale, Centre Medical Universitaire, Universite de Geneve, Geneva, Switzerland
    Proc Natl Acad Sci U S A 94:3679-84. 1997
  2. ncbi request reprint Positive control of the two-component RcsC/B signal transduction network by DjlA: a member of the DnaJ family of molecular chaperones in Escherichia coli
    W L Kelley
    Departement de Biochimie Medicale, Universite de Geneve, Switzerland
    Mol Microbiol 25:913-31. 1997
  3. ncbi request reprint The J-domain family and the recruitment of chaperone power
    W L Kelley
    Dept de Biochimie Médicale, Centre Medical Universitaire, Universite de Geneve, Switzerland
    Trends Biochem Sci 23:222-7. 1998
  4. ncbi request reprint Molecular chaperones: How J domains turn on Hsp70s
    W L Kelley
    Departement de Biochimie Medicale, CMU Université de Genève, 1 rue Michel Servet, 1211 Geneve 4, Switzerland
    Curr Biol 9:R305-8. 1999
  5. pmc Structure-function analyses of the Ssc1p, Mdj1p, and Mge1p Saccharomyces cerevisiae mitochondrial proteins in Escherichia coli
    O Deloche
    , , Geneva, Switzerland
    J Bacteriol 179:6066-75. 1997
  6. pmc The djlA gene acts synergistically with dnaJ in promoting Escherichia coli growth
    P Genevaux
    Departement de Biochimie Medicale, Centre Medical Universitaire, Universite de Geneve, 1211 Geneve 4, Switzerland
    J Bacteriol 183:5747-50. 2001
  7. ncbi request reprint DjlA is a third DnaK co-chaperone of Escherichia coli, and DjlA-mediated induction of colanic acid capsule requires DjlA-DnaK interaction
    P Genevaux
    Departement de Biochimie Medicale, Centre Medical Universitaire, Universite de Geneve, 1, rue Michel Servet, 1211 Geneve 4, Switzerland
    J Biol Chem 276:7906-12. 2001
  8. pmc Replication terminator protein of Escherichia coli is a transcriptional repressor of its own synthesis
    S Natarajan
    Department of Microbiology and Immunology, Duke University Medical Center, Durham, NC 27710
    Proc Natl Acad Sci U S A 88:3867-71. 1991

Collaborators

Detail Information

Publications8

  1. pmc The T/t common exon of simian virus 40, JC, and BK polyomavirus T antigens can functionally replace the J-domain of the Escherichia coli DnaJ molecular chaperone
    W L Kelley
    Departement de Biochimie Medicale, Centre Medical Universitaire, Universite de Geneve, Geneva, Switzerland
    Proc Natl Acad Sci U S A 94:3679-84. 1997
    ..This finding has implications for the regulation of DNA tumor virus T antigens by molecular chaperones...
  2. ncbi request reprint Positive control of the two-component RcsC/B signal transduction network by DjlA: a member of the DnaJ family of molecular chaperones in Escherichia coli
    W L Kelley
    Departement de Biochimie Medicale, Universite de Geneve, Switzerland
    Mol Microbiol 25:913-31. 1997
    ....
  3. ncbi request reprint The J-domain family and the recruitment of chaperone power
    W L Kelley
    Dept de Biochimie Médicale, Centre Medical Universitaire, Universite de Geneve, Switzerland
    Trends Biochem Sci 23:222-7. 1998
    ..J-domain proteins participate in complex biological processes, such as cell-cycle control by DNA tumor viruses, regulation of protein kinases and exocytosis...
  4. ncbi request reprint Molecular chaperones: How J domains turn on Hsp70s
    W L Kelley
    Departement de Biochimie Medicale, CMU Université de Genève, 1 rue Michel Servet, 1211 Geneve 4, Switzerland
    Curr Biol 9:R305-8. 1999
    ..They are assisted in this role by their Hsp40 partners, and recent studies have shed new light on how the 'J domains' of these 'cochaperones' activate substrate binding by Hsp70 molecules...
  5. pmc Structure-function analyses of the Ssc1p, Mdj1p, and Mge1p Saccharomyces cerevisiae mitochondrial proteins in Escherichia coli
    O Deloche
    , , Geneva, Switzerland
    J Bacteriol 179:6066-75. 1997
    ..coli. We were unable to demonstrate any functional complementation by Ssc1p, even when coexpressed with its Mdj1p cochaperone in E. coli...
  6. pmc The djlA gene acts synergistically with dnaJ in promoting Escherichia coli growth
    P Genevaux
    Departement de Biochimie Medicale, Centre Medical Universitaire, Universite de Geneve, 1211 Geneve 4, Switzerland
    J Bacteriol 183:5747-50. 2001
    ..This essentiality depended upon the J domain of DjlA but not upon the normal membrane location of DjlA...
  7. ncbi request reprint DjlA is a third DnaK co-chaperone of Escherichia coli, and DjlA-mediated induction of colanic acid capsule requires DjlA-DnaK interaction
    P Genevaux
    Departement de Biochimie Medicale, Centre Medical Universitaire, Universite de Geneve, 1, rue Michel Servet, 1211 Geneve 4, Switzerland
    J Biol Chem 276:7906-12. 2001
    ..Collectively, these results demonstrate that DjlA is a co-chaperone for DnaK and that this chaperone-co-chaperone pair is implicated directly, or indirectly, in the regulation of colanic acid capsule...
  8. pmc Replication terminator protein of Escherichia coli is a transcriptional repressor of its own synthesis
    S Natarajan
    Department of Microbiology and Immunology, Duke University Medical Center, Durham, NC 27710
    Proc Natl Acad Sci U S A 88:3867-71. 1991
    ..Therefore, Ter protein can serve as a transcriptional repressor of its own synthesis by preventing RNA polymerase from binding to the tus promoter when both proteins are present in the cell milieu...