Jean Paul Janssens

Summary

Affiliation: University Hospital
Country: Switzerland

Publications

  1. ncbi request reprint Non-invasive (transcutaneous) monitoring of PCO2 (TcPCO2) in older adults
    Jean Paul Janssens
    Geriatric University Hospital, Thonex, Switzerland
    Gerontology 51:174-8. 2005
  2. doi request reprint Contact tracing for tuberculosis and treatment for latent infection in a low incidence country
    Elisabeth Langenskiold
    Division of Pulmonary Diseases, CHUV, Lausanne, Switzerland
    Swiss Med Wkly 138:78-84. 2008
  3. ncbi request reprint Aging of the respiratory system: impact on pulmonary function tests and adaptation to exertion
    Jean Paul Janssens
    Outpatient Section of the Division of Pulmonary Diseases, Geneva University Hospital, 1211 Geneva 14, Switzerland
    Clin Chest Med 26:469-84, vi-vii. 2005
  4. ncbi request reprint Quantitative scoring of an interferon-gamma assay for differentiating active from latent tuberculosis
    J P Janssens
    Centre antituberculeux, Hopital Cantonal Universitaire, 1211, Geneva 14, Switzerland
    Eur Respir J 30:722-8. 2007
  5. doi request reprint Impact of volume targeting on efficacy of bi-level non-invasive ventilation and sleep in obesity-hypoventilation
    Jean Paul Janssens
    Division of Pulmonary Diseases, Geneva University Hospital, Geneva, Switzerland
    Respir Med 103:165-72. 2009
  6. doi request reprint Contribution of a IFN-gamma assay in contact tracing for tuberculosis in a low-incidence, high immigration area
    Jean Paul Janssens
    Division of Pulmonary Diseases, Geneva University Hospital, Geneva, Switzerland
    Swiss Med Wkly 138:585-93. 2008
  7. ncbi request reprint Pneumonia in the elderly (geriatric) population
    Jean Paul Janssens
    Division of Lung Diseases, Geneva University Hospital, Geneva, Switzerland
    Curr Opin Pulm Med 11:226-30. 2005
  8. ncbi request reprint Validity and reliability of a French version of the MRF-28 health-related quality of life questionnaire
    Jean Paul Janssens
    Division of Pulmonary Diseases, Geneva University Hospital, Geneva, Switzerland
    Respiration 71:567-74. 2004
  9. doi request reprint Nocturnal monitoring of home non-invasive ventilation: the contribution of simple tools such as pulse oximetry, capnography, built-in ventilator software and autonomic markers of sleep fragmentation
    Jean Paul Janssens
    Centre antituberculeux, Division of Pulmonary Diseases, Geneva University Hospital, Rue Gabrielle Perret Gentil 4, 1211 Geneva 14, Switzerland
    Thorax 66:438-45. 2011
  10. ncbi request reprint [Critical approach to the use of blood tests measuring gamma-interferon when suspecting active tuberculosis: clinical cases]
    Jean Paul Janssens
    Centre antituberculeux, HUG, 1211 Geneve 14
    Rev Med Suisse 2:2620-2, 2624-5. 2006

Collaborators

Detail Information

Publications50

  1. ncbi request reprint Non-invasive (transcutaneous) monitoring of PCO2 (TcPCO2) in older adults
    Jean Paul Janssens
    Geriatric University Hospital, Thonex, Switzerland
    Gerontology 51:174-8. 2005
    ..However, age-related changes in skin perfusion, metabolism, or thickness may alter the validity of the technique...
  2. doi request reprint Contact tracing for tuberculosis and treatment for latent infection in a low incidence country
    Elisabeth Langenskiold
    Division of Pulmonary Diseases, CHUV, Lausanne, Switzerland
    Swiss Med Wkly 138:78-84. 2008
    ..To determine the yield of contact tracing after exposure to active tuberculosis (TB) cases in a low incidence area for TB as well as completion rate and tolerance to treatment for latent TB infection (LTBI)...
  3. ncbi request reprint Aging of the respiratory system: impact on pulmonary function tests and adaptation to exertion
    Jean Paul Janssens
    Outpatient Section of the Division of Pulmonary Diseases, Geneva University Hospital, 1211 Geneva 14, Switzerland
    Clin Chest Med 26:469-84, vi-vii. 2005
    ..In spite of these changes, the respiratory system remains capable of maintaining adequate gas exchange at rest and during exertion during the entire lifespan, with only a slight decrease in Pa(O2) and no significant change in Pa(CO2)...
  4. ncbi request reprint Quantitative scoring of an interferon-gamma assay for differentiating active from latent tuberculosis
    J P Janssens
    Centre antituberculeux, Hopital Cantonal Universitaire, 1211, Geneva 14, Switzerland
    Eur Respir J 30:722-8. 2007
    ..Although T-SPOT.TB results were significantly related to disease activity, the test cannot be recommended for the diagnosis of tuberculosis...
  5. doi request reprint Impact of volume targeting on efficacy of bi-level non-invasive ventilation and sleep in obesity-hypoventilation
    Jean Paul Janssens
    Division of Pulmonary Diseases, Geneva University Hospital, Geneva, Switzerland
    Respir Med 103:165-72. 2009
    ..Although it may improve nocturnal ventilation, we hypothesized that increased pressure swings related to volume targeting may have a deleterious effect on sleep structure and patient comfort...
  6. doi request reprint Contribution of a IFN-gamma assay in contact tracing for tuberculosis in a low-incidence, high immigration area
    Jean Paul Janssens
    Division of Pulmonary Diseases, Geneva University Hospital, Geneva, Switzerland
    Swiss Med Wkly 138:585-93. 2008
    ..TB and TST in Bacillus of Calmette-Guérin (BCG) vaccinated and non-vaccinated subjects, and 3) impact of results of T-SPOT.TB on diagnosis and treatment for latent tuberculosis infection (LTBI)...
  7. ncbi request reprint Pneumonia in the elderly (geriatric) population
    Jean Paul Janssens
    Division of Lung Diseases, Geneva University Hospital, Geneva, Switzerland
    Curr Opin Pulm Med 11:226-30. 2005
    ..Review of recent studies (2003 and 2004) concerning pneumonia in the very old...
  8. ncbi request reprint Validity and reliability of a French version of the MRF-28 health-related quality of life questionnaire
    Jean Paul Janssens
    Division of Pulmonary Diseases, Geneva University Hospital, Geneva, Switzerland
    Respiration 71:567-74. 2004
    ..Evaluation of health-related quality of life (HRQL) in chronic respiratory failure (CRF) is an important issue for evaluating the impact of treatment...
  9. doi request reprint Nocturnal monitoring of home non-invasive ventilation: the contribution of simple tools such as pulse oximetry, capnography, built-in ventilator software and autonomic markers of sleep fragmentation
    Jean Paul Janssens
    Centre antituberculeux, Division of Pulmonary Diseases, Geneva University Hospital, Rue Gabrielle Perret Gentil 4, 1211 Geneva 14, Switzerland
    Thorax 66:438-45. 2011
    ..Finally, autonomic markers of sympathetic tone using signals such as pulse wave amplitude of the pulse oximetry signal can provide reliable information of sleep fragmentation...
  10. ncbi request reprint [Critical approach to the use of blood tests measuring gamma-interferon when suspecting active tuberculosis: clinical cases]
    Jean Paul Janssens
    Centre antituberculeux, HUG, 1211 Geneve 14
    Rev Med Suisse 2:2620-2, 2624-5. 2006
    ..Their main indication remains the detection of LTBI in screening or contact tracing, or in immuno-compromised subjects...
  11. doi request reprint What does built-in software of home ventilators tell us? An observational study of 150 patients on home ventilation
    Patrick Pasquina
    Division of Pulmonary Diseases, Geneva University Hospital, Geneva, Switzerland
    Respiration 83:293-9. 2012
    ..However, for many of these variables, there is neither consensus nor documentation as to what is to be expected in a population of stable patients under noninvasive ventilation (NIV)...
  12. doi request reprint Do results of the T-SPOT.TB interferon-gamma release assay change after treatment of tuberculosis?
    Valerie Bosshard
    Division of Pulmonary Diseases, Geneva University Hospital, 1211 Geneva 14, Switzerland
    Respir Med 103:30-4. 2009
    ..Interferon-gamma (IFN-gamma) production by lymphocytes exposed to antigens specific of Mycobacterium tuberculosis has been shown to correlate with antigen load and disease activity...
  13. doi request reprint Sleep in ventilatory failure in restrictive thoracic disorders. Effects of treatment with non invasive ventilation
    Olivier Contal
    Division of Pulmonary Diseases, Geneva University Hospitals, 1211 Geneva 14, Switzerland
    Sleep Med 12:373-7. 2011
    ..Non-invasive ventilation (NIV) may improve arterial blood gases but may adversely affect sleep. We assessed sleep structure and blood gases before and during NIV in patients with restrictive disorders in hypercapnic ventilatory failure...
  14. pmc Polysomnography in stable COPD under non-invasive ventilation to reduce patient-ventilator asynchrony and morning breathlessness
    Dan Adler
    Division of Pulmonary Diseases, Geneva University Hospitals, Rue Gabrielle Perret Gentil 4, 1211, Geneva 14, Switzerland
    Sleep Breath 16:1081-90. 2012
    ..We hypothesised that in these patients, progressive hyperinflation, resulting from inappropriate ventilator settings, leads to patient-ventilator asynchrony (PVA) with a high rate of unrewarded inspiratory efforts and morning discomfort...
  15. ncbi request reprint Impact of different backup respiratory rates on the efficacy of noninvasive positive pressure ventilation in obesity hypoventilation syndrome: a randomized trial
    Olivier Contal
    Division of Pulmonary Diseases, Department of Psychiatry, Geneva University Hospitals, Geneva, Switzerland
    Chest 143:37-46. 2013
    ....
  16. ncbi request reprint [Non invasive ventilation in the ICU for the neuromuscular patient: legal issues]
    Jean Claude Chevrolet
    Service des Soins Intensifs, HUG, 1211 Geneve 14
    Rev Med Suisse 6:2396, 2398-400. 2010
    ....
  17. ncbi request reprint Changing patterns in long-term noninvasive ventilation: a 7-year prospective study in the Geneva Lake area
    Jean Paul Janssens
    Pulmonary Division, Geneva University Hospital, Geneva, Switzerland
    Chest 123:67-79. 2003
    ..To describe a 7-year follow-up (1992 to 2000) of patients who were treated by home nasal positive-pressure ventilation (NPPV) for chronic hypercapnic respiratory failure...
  18. ncbi request reprint Effect of a comprehensive, multidisciplinary, educational program on the use of antibiotics in a geriatric university hospital
    Monika Lutters
    Department of Geriatrics, University Hospitals of Geneva, Geneva, Switzerland
    J Am Geriatr Soc 52:112-6. 2004
    ..To assess the effect of a comprehensive, educational antibiotic management program designed to improve antibiotic use and reduce treatment costs in elderly patients with suspected urinary or respiratory tract infection...
  19. ncbi request reprint Pneumonia in the very old
    Jean Paul Janssens
    Division of Lung Diseases and Department of Geriatrics, Geneva University Hospitals, Geneva, Switzerland
    Lancet Infect Dis 4:112-24. 2004
    ....
  20. doi request reprint Contribution of interferon-γ release assays (IGRAs) to the diagnosis of latent tuberculosis infection after renal transplantation
    Karine Hadaya
    Division of Nephrology, Geneva University Hospitals, Geneva, Switzerland
    Transplantation 95:1485-90. 2013
    ..Detecting LTBI in this population is therefore important to prevent active TB. The tuberculin skin test (TST) has a poor sensitivity in this setting...
  21. doi request reprint Pulse transit time as a measure of respiratory effort under noninvasive ventilation
    Olivier Contal
    Division of Pulmonary Diseases, Geneva University Hospitals, Geneva, Switzerland
    Eur Respir J 41:346-53. 2013
    ..PTT during sleep is also useful to differentiate central from obstructive respiratory events occurring under NIV...
  22. ncbi request reprint [A lung specialist in ALS care: towards less pessimism]
    Dan Adler
    Service de Pneumologie, HUG, 1211 Geneve 14
    Rev Med Suisse 5:2329-32, 2334-5. 2009
    ..This evidence-based review focuses on respiratory care of patients with ALS...
  23. doi request reprint Upper-respiratory viral infection, biomarkers, and COPD exacerbations
    Omar Kherad
    Department of Internal Medicine, Geneva s University Hospitals and University of Geneva, Geneva, Switzerland
    Chest 138:896-904. 2010
    ..The usefulness of procalcitonin and C-reactive protein as indicators of the presence or absence of viral infection in this setting also needs to be evaluated...
  24. ncbi request reprint Chronic hypoxia: common traits between chronic obstructive pulmonary disease and altitude
    Comasia A Raguso
    Division of Clinical Nutrition, University Hospital, Geneva, Switzerland
    Curr Opin Clin Nutr Metab Care 7:411-7. 2004
    ..This paper reviews recent literature regarding the effects of chronic exposure to hypoxia on metabolism, particularly comparing chronic obstructive pulmonary disease patients with humans exposed to high altitude...
  25. ncbi request reprint Successful treatment of disseminated tuberculosis and acquired immunodeficiency syndrome in an 81-y-old woman
    André Laszlo
    Department of Geriatrics, Geneva University Hospital, Geneva, Switzerland
    Scand J Infect Dis 35:420-2. 2003
    ..Antiretroviral therapy initiated 2 months after the introduction of tuberculostatic treatment was well tolerated, with a 12 month follow-up...
  26. doi request reprint Monitoring of noninvasive ventilation by built-in software of home bilevel ventilators: a bench study
    Olivier Contal
    Division of Pulmonary Diseases, Geneva University Hospital, Geneva, Switzerland
    Chest 141:469-76. 2012
    ..However, to our knowledge, the validity of this information has not yet been independently assessed...
  27. pmc Clinical presentation, demographics and outcome of tuberculosis (TB) in a low incidence area: a 4-year study in Geneva, Switzerland
    Omar Kherad
    Department of Internal Medicine Geneva University Hospitals and University of Geneva, Geneva, Switzerland
    BMC Infect Dis 9:217. 2009
    ..The aim of this study was to describe clinical and social characteristics of patients with TB and their outcome in a low incidence area with a high immigration rate...
  28. ncbi request reprint [Follow-up of patients with home mechanical ventilation: experience in Geneva, Switzerland]
    Patrick Pasquina
    Service de Pneumologie, HUG, 1211 Geneve 14
    Rev Med Suisse 4:2518-20, 2522-4. 2008
    ..A specialized team of nurses monitors closely at home clinical evolution, and compliance, gathering an important amount of clinical data, and allowing the early detection of clinical deterioration...
  29. ncbi request reprint [Non invasive ventilation in the ICU for the neuromuscular patient: ethical issues]
    Jean Claude Chevrolet
    Service des Soins Intensifs, HUG, 1211 Geneve 14
    Rev Med Suisse 6:2390-5. 2010
    ..In a second parent paper of this issue, we discuss the medico-legal implications of mechanical ventilation in neuromuscular failure, particularly the end-of-life aspects...
  30. ncbi request reprint Body composition in patients with chronic hypercapnic respiratory failure
    Ursula G Kyle
    Division of Clinical Nutrition, Geneva University Hospital, Rue Micheli du Crest 24, 1211 Geneva, Switzerland
    Respir Med 100:244-52. 2006
    ....
  31. ncbi request reprint Rapid eye movement-related disordered breathing: clinical and polysomnographic features
    José Haba-Rubio
    Sleep Laboratory, Department of Psychiatry, University Hospital, Geneva, Switzerland
    Chest 128:3350-7. 2005
    ..The aim of the study was to define the frequency and the clinical and polysomnographic features of REM SDB in a large clinical population...
  32. doi request reprint Interferon-gamma release assays versus tuberculin skin testing for detection of latent tuberculosis in chronic haemodialysis patients
    Pierre Alain Triverio
    Division of Nephrology, Geneva University Hospital, 1211 Geneva 14, Switzerland
    Nephrol Dial Transplant 24:1952-6. 2009
    ..End stage renal disease increases the risk of reactivating latent tuberculosis (LTBI). Interferon-gamma release assays (IGRA) are an alternative to the tuberculin skin test (TST) for detecting LTBI...
  33. ncbi request reprint Respiratory patterns during sleep in obesity-hypoventilation patients treated with nocturnal pressure support: a preliminary report
    Yan Fei Guo
    Centre antituberculeux, Service de Pneumologie, Hopitaux Universitaires de Geneve, 25 rue Micheli du Crest, 1211 Geneva 14, Switzerland
    Chest 131:1090-9. 2007
    ....
  34. ncbi request reprint [Is there a role for prophylactic antibiotic treatment with macrolides in bronchiectasis?]
    Mélanie Bochet
    Service de médecine interne générale, Departement de Medecine Interne, HUG, Geneve
    Rev Med Suisse 7:308, 310-2. 2011
    ..Until larger studies with long-term follow up are available, the use of macrolides in bronchiectasis should be restricted to selected cases and should take into account their potential side effects...
  35. ncbi request reprint Management of patients with amyotrophic lateral sclerosis
    Sophie Pautex
    CESCO, Department of Rehabilitation and Geriatrics, University Hospital Geneva, Collone Bellerive, Switzerland
    Swiss Med Wkly 135:626-9. 2005
    ..Standard recommendations for the clinical management of patient with ALS have been edited in recent years. These documents emphasise the importance of patient's autonomy...
  36. ncbi request reprint [Role of long-acting beta-agonists in the treatment of asthma]
    Christophe Marti
    Service de médecine interne générale, HUG, 1211 Geneve 14
    Rev Med Suisse 4:2203-4, 2206-7. 2008
    ..Inhaled corticosteroids (ICS) is the preferred asthma controller option and LABA should be used only in association with ICS in patients insufficiently controlled under ICS therapy...
  37. ncbi request reprint [Long-term oxygen therapy]
    Grégoire Gex
    Service de médecine interne générale, HUG, Geneve
    Rev Med Suisse 3:2646, 2648-50, 2652-4. 2007
    ..The characteristics of the three methods of oxygen delivery for domiciliary treatment are discussed in this review...
  38. ncbi request reprint Pulmonary cement embolism after vertebroplasty
    Marc Righini
    Division of Angiology and Hemostasis, Geneva University Hospital, 24 Rue Micheli du Crest, 1211 Geneva 14, Switzerland
    Thromb Haemost 95:388-9. 2006
  39. ncbi request reprint [Early exercise training after exacerbation in patients with chronic respiratory failure]
    Hiromitsu Takahashi
    Service de physiothérapie, Centre antituberculeux, HUG, Geneve
    Rev Med Suisse 7:2301-2, 2304-6. 2011
    ....
  40. doi request reprint Adverse effects and adherence to treatment of rifampicin 4 months vs isoniazid 6 months for latent tuberculosis: a retrospective analysis
    Isabelle Frésard
    Division of Pneumology, Geneva University Hospitals, 4, rue Gabrielle Perret Gentil, 1211 Geneva 14, Switzerland
    Swiss Med Wkly 141:w13240. 2011
    ....
  41. ncbi request reprint Ascites and highly elevated CA-125 levels in a case of peritoneal tuberculosis
    Alain B Younossian
    Division of Pulmonary Diseases, Geneva University Hospital, Switzerland
    Scand J Infect Dis 38:216-8. 2006
    ..Both clinical symptoms and CA-125 levels regressed under tuberculostatic treatment...
  42. doi request reprint Perception of chronic respiratory impairment in patients' drawings
    Christophe Luthy
    Division of General Medical Rehabilitation, Geneva University Hospitals, Geneva, Switzerland
    J Rehabil Med 45:694-700. 2013
    ..To explore the perception of dyspnoea in patients with severe chronic obstructive pulmonary disease...
  43. ncbi request reprint [Tuberculosis and HIV co-infection: a therapeutic challenge]
    Florian Charbonnier
    Service de Pneumologie, Département des spécialités de médecine, HUG, 1211 Geneve 14
    Rev Med Suisse 7:2295-6, 2298-300. 2011
    ....
  44. ncbi request reprint [Pneumology. Should we fear inhaled anticholinergic bronchodilators?]
    Thierry Rochat
    Service de Pneumologie, HUG, 1211 Geneve 14
    Rev Med Suisse 5:135-7. 2009
    ..However the treatment did not attenuate the annual decline of lung function, and did not decrease mortality in these patients...
  45. ncbi request reprint Knowledge of guidelines for the management of COPD: a survey of primary care physicians
    Olivier T Rutschmann
    Emergency Medicine Unit, Department of Medicine, Geneva University Hospital, 24 Rue Micheli du Crest, 1221 Geneva 14, Switzerland
    Respir Med 98:932-7. 2004
    ..To evaluate primary care physicians' knowledge of guidelines for the management of COPD...
  46. ncbi request reprint [Immunization and immuno-modulation for prevention of respiratory tract infections]
    Jesica Mazza-Stalder
    Service de Pneumologie, HUG, 1211 Geneve 14
    Rev Med Suisse 1:2645-6, 2649-51. 2005
    ..In patients with diffuse bronchiectasis, the immunomodulatory effect of macrolides, and the use of inhaled corticosteroids should be confirmed by larger clinical investigations...
  47. ncbi request reprint Performance characteristics of 10 home mechanical ventilators in pressure-support mode: a comparative bench study
    Anne Battisti
    Department of Medical Intensive Care, Hopital Cantonal Universitaire, Geneva, Switzerland
    Chest 127:1784-92. 2005
    ..The present bench study was designed to compare the various characteristics of 10 recently developed bilevel Pi devices under different conditions of respiratory mechanics...
  48. ncbi request reprint Comparison of airway resistance measurements by the forced oscillation technique and the interrupter technique for detecting chronic obstructive pulmonary disease in elderly patients
    Yan Fei Guo
    Division of Pulmonary Medicine, Beijing Hospital, Beijing 100730, China
    Chin Med J (Engl) 118:1921-4. 2005
  49. doi request reprint Clinical utility of the interferon-{gamma} release assay for elderly patients with active tuberculosis: a word of caution
    Jean Paul Janssens
    Chest 134:471-2. 2008
  50. ncbi request reprint Walking activity measured by accelerometry during respiratory rehabilitation
    Marcos Coronado
    Centre de Réhabilitation Respiratoire, Hôpital de Rolle, 1011 Lausanne, Switzerland
    J Cardiopulm Rehabil 23:357-64. 2003
    ..This study aimed to assess the usefulness of a new accelerometric method for characterization of walking activity during a 3-week inpatient rehabilitation program...