Gunther F L Hofbauer

Summary

Affiliation: University Hospital
Country: Switzerland

Publications

  1. doi request reprint Organ transplantation and skin--principles and concepts
    Gunther F L Hofbauer
    Dermatologische Klinik, Universitatsspital Zurich, Gloriastrasse 31, Zurich, Switzerland
    Curr Probl Dermatol 43:1-8. 2012
  2. doi request reprint [Phototherapy and carcinogenesis]
    G Hofbauer
    Dermatologische Klinik, Universitatsspital Zurich, Gloriastr 31, 8091, Zurich, Schweiz
    Hautarzt 64:349-53. 2013
  3. doi request reprint Reversal of UVA skin photosensitivity and DNA damage in kidney transplant recipients by replacing azathioprine
    G F L Hofbauer
    Department of Dermatology, University Hospital Zurich, Switzerland
    Am J Transplant 12:218-25. 2012
  4. doi request reprint Organ transplantation and skin cancer: basic problems and new perspectives
    Gunther F L Hofbauer
    Department of Dermatology, University Hospital Zurich, Switzerland
    Exp Dermatol 19:473-82. 2010
  5. doi request reprint [Immunosuppressive therapy after transplantation. Dermatologic relevance and pathomechanisms]
    G Hofbauer
    Dermatologische Klinik, Universitatsspital Zurich, Gloriastr 31, 8091, Zurich, Schweiz
    Hautarzt 61:214-9. 2010
  6. doi request reprint The mTOR inhibitor rapamycin significantly improves facial angiofibroma lesions in a patient with tuberous sclerosis
    G F L Hofbauer
    Department of Dermatology, University Hospital, Zurich, Switzerland
    Br J Dermatol 159:473-5. 2008
  7. doi request reprint Swiss clinical practice guidelines for skin cancer in organ transplant recipients
    G F Hofbauer
    Dermatologische Klinik, Universitatsspital Zurich, Kantonsspital St Gallen, Zurich, Switzerland
    Swiss Med Wkly 139:407-15. 2009
  8. doi request reprint Pronounced allelic imbalance at D9S162 in skin squamous cell carcinoma of organ transplant recipients
    Beda Mühleisen
    Department of Dermatology, University Hospital Zurich, Zurich, Switzerland
    Arch Dermatol 148:697-703. 2012
  9. doi request reprint Progression of cutaneous squamous cell carcinoma in immunosuppressed patients is associated with reduced CD123+ and FOXP3+ cells in the perineoplastic inflammatory infiltrate
    Beda Mühleisen
    Department of Dermatology, University Hospital Zurich, Zurich, Switzerland
    Histopathology 55:67-76. 2009
  10. doi request reprint Pre- and posttransplant management of solid organ transplant recipients: risk-adjusted follow-up
    Bahar Shafaeddin Schreve
    Dermatologische Klinik, Universitatsspital Zurich, Gloriastrasse 31, Zurich, Switzerland
    Curr Probl Dermatol 43:57-70. 2012

Collaborators

Detail Information

Publications34

  1. doi request reprint Organ transplantation and skin--principles and concepts
    Gunther F L Hofbauer
    Dermatologische Klinik, Universitatsspital Zurich, Gloriastrasse 31, Zurich, Switzerland
    Curr Probl Dermatol 43:1-8. 2012
    ....
  2. doi request reprint [Phototherapy and carcinogenesis]
    G Hofbauer
    Dermatologische Klinik, Universitatsspital Zurich, Gloriastr 31, 8091, Zurich, Schweiz
    Hautarzt 64:349-53. 2013
    ....
  3. doi request reprint Reversal of UVA skin photosensitivity and DNA damage in kidney transplant recipients by replacing azathioprine
    G F L Hofbauer
    Department of Dermatology, University Hospital Zurich, Switzerland
    Am J Transplant 12:218-25. 2012
    ..Replacing azathioprine selectively reduced the skin photosensitivity to UVA, attenuated UVA-induced skin DNA damage, and is likely based on incorporated 6-TG in DNA...
  4. doi request reprint Organ transplantation and skin cancer: basic problems and new perspectives
    Gunther F L Hofbauer
    Department of Dermatology, University Hospital Zurich, Switzerland
    Exp Dermatol 19:473-82. 2010
    ....
  5. doi request reprint [Immunosuppressive therapy after transplantation. Dermatologic relevance and pathomechanisms]
    G Hofbauer
    Dermatologische Klinik, Universitatsspital Zurich, Gloriastr 31, 8091, Zurich, Schweiz
    Hautarzt 61:214-9. 2010
    ..Switching calcineurin inhibitors to mTOR inhibitors is probably to be recommended, while omitting azathioprine may potentially be advisable in recurrent SCC...
  6. doi request reprint The mTOR inhibitor rapamycin significantly improves facial angiofibroma lesions in a patient with tuberous sclerosis
    G F L Hofbauer
    Department of Dermatology, University Hospital, Zurich, Switzerland
    Br J Dermatol 159:473-5. 2008
    ..Immunosuppressive treatment with rapamycin, a specific mTOR inhibitor, initiated because of renal transplantation, reduced facial angiofibroma dramatically...
  7. doi request reprint Swiss clinical practice guidelines for skin cancer in organ transplant recipients
    G F Hofbauer
    Dermatologische Klinik, Universitatsspital Zurich, Kantonsspital St Gallen, Zurich, Switzerland
    Swiss Med Wkly 139:407-15. 2009
    ..Chemoprevention with the retinoid acitretin reduces the recurrence rate of SCC. The dermatological follow-up of SOTRs should be integrated into the comprehensive post-transplant care...
  8. doi request reprint Pronounced allelic imbalance at D9S162 in skin squamous cell carcinoma of organ transplant recipients
    Beda Mühleisen
    Department of Dermatology, University Hospital Zurich, Zurich, Switzerland
    Arch Dermatol 148:697-703. 2012
    ..To evaluate chromosomal instability at 9p21-22 with p16 protein expression in organ transplant recipients (OTRs) compared with immunocompetent patients with squamous cell carcinoma (SCC)...
  9. doi request reprint Progression of cutaneous squamous cell carcinoma in immunosuppressed patients is associated with reduced CD123+ and FOXP3+ cells in the perineoplastic inflammatory infiltrate
    Beda Mühleisen
    Department of Dermatology, University Hospital Zurich, Zurich, Switzerland
    Histopathology 55:67-76. 2009
    ..The aim was to determine whether qualitative and quantitative differences in perineoplastic inflammation in OTRs contribute to the increased carcinogenesis...
  10. doi request reprint Pre- and posttransplant management of solid organ transplant recipients: risk-adjusted follow-up
    Bahar Shafaeddin Schreve
    Dermatologische Klinik, Universitatsspital Zurich, Gloriastrasse 31, Zurich, Switzerland
    Curr Probl Dermatol 43:57-70. 2012
    ..The dermatological follow-up of SOTR should be integrated into the comprehensive posttransplant care...
  11. doi request reprint Immunosuppression affects CD4+ mRNA expression and induces Th2 dominance in the microenvironment of cutaneous squamous cell carcinoma in organ transplant recipients
    Maria Kosmidis
    Department of Dermatology, University Hospital Zurich, Gloriastrasse, Zurich, Switzerland
    J Immunother 33:538-46. 2010
    ....
  12. ncbi request reprint Painless erythema of the hands associated with non-Hodgkin's lymphoma in a lung transplant recipient
    Gunther F L Hofbauer
    Department of Dermatology, University Hospital, Zurich, Switzerland
    J Am Acad Dermatol 46:S159-60. 2002
    ..Acral erythema has been reported in association with chemotherapy, collagen vascular disease, infections as with HIV, hepatitis C virus, parvovirus B19, or cytomegalovirus. None of the described associations were detected in this case...
  13. doi request reprint Persistent photodamage following drug photosensitization in a lung-transplant recipient
    Eva Sailer
    Department of Dermatology, University Hospital, Zurich, Switzerland
    Photodermatol Photoimmunol Photomed 27:213-5. 2011
    ..Several transient phototoxic drug reactions have been described. We report a case of a persistent phototoxic reaction to ciprofloxacin in a lung-transplant recipient on a long-term immunosuppressive drug regimen...
  14. doi request reprint Squamous cell carcinoma of the skin induces considerable sustained cost of care in organ transplant recipients
    Christian P Rüegg
    Department of Dermatology, Zurich University Hospital, Zurich, Switzerland
    J Am Acad Dermatol 67:1242-9. 2012
    ..Squamous cell carcinoma (SCC) is the most frequent cancer in organ transplant recipients (OTR)...
  15. doi request reprint Immune phenotype of peripheral blood cells and skin squamous cell carcinoma in organ transplant recipients
    Piotr Dziunycz
    Department of Dermatology, University Hospital Zurich, Gloriastrasse 31, 8091 Zurich, Switzerland
    Expert Rev Clin Immunol 6:359-62. 2010
    ..provide us with a tool to aid recognition of patients at a higher risk for SCC. Further studies will help to translate these findings into potentially useful tools for the dermatological management of kidney transplant recipients...
  16. doi request reprint IL-31 expression by inflammatory cells is preferentially elevated in atopic dermatitis
    Stephan Nobbe
    Department of Dermatology, University Hospital Zurich, Switzerland
    Acta Derm Venereol 92:24-8. 2012
    ..Our results confirm, at the protein level, the relationship between IL-31 expression and atopic dermatitis. Our results do not support a general relationship between expression of IL-31/IL-31R and pruritic or Th2-mediated diseases...
  17. doi request reprint Methylaminolaevulinic acid photodynamic therapy in the treatment of erythroplasia of Queyrat
    Laurence Feldmeyer
    Dermatology Department, University Hospital Zurich, Zurich, Switzerland
    Dermatology 223:52-6. 2011
    ..Photodynamic therapy (PDT) employs a photosensitizer excited by visible light. The resulting photodynamic reaction selectively destroys atypical cells. Only few reports exist on the use of topical PDT in the treatment of EQ...
  18. doi request reprint Granulomatous slack skin responds to UVA1 phototherapy
    Patrick A Oberholzer
    Department of Dermatology, University Hospital Zurich, Zurich, Switzerland
    Dermatology 219:268-71. 2009
    ..A follow-up 12 months after phototherapy showed continued treatment benefit. To our knowledge, this is the first report describing the successful use of UVA1 (340-400 nm) phototherapy in a patient with GSS...
  19. doi request reprint Critical skin cancer in organ transplant recipients--a dermatopathological view
    Werner Kempf
    Kempf and Pfaltz, Histological Diagnostics, University Hospital Zurich, Seminarstrasse 1, Zurich, Switzerland
    Curr Probl Dermatol 43:18-35. 2012
    ..This review discusses the histopathological aspects of skin cancers in OTR, the impact of dermatopathological analysis on prognosis and understanding of the pathogenesis of these neoplasms...
  20. doi request reprint Facial blaschkitis: case and review
    Laurence Imhof
    Department of Dermatology, University Hospital, Zurich, Switzerland
    Dermatology 223:1-3. 2011
    ..However, the unusual clinical presentation as well as the resistance to antimalarial drugs do not fully allow to confirm this suspicion. Therefore, we recommend to call this new entity LE-like facial Blaschkitis of the adult...
  21. doi request reprint Clinical phase I intratumoral administration of two recombinant ALVAC canarypox viruses expressing human granulocyte-macrophage colony-stimulating factor or interleukin-2: the transgene determines the composition of the inflammatory infiltrate
    Gunther F L Hofbauer
    Department of Dermatology, University Hospital Zurich, Zurich, Switzerland
    Melanoma Res 18:104-11. 2008
    ..Local GM-CSF expression could be induced. In summary, ALVAC GM-CSF and ALVAC IL-2 injections are safe and can mediate local biologic and immunologic effects...
  22. doi request reprint [Photochemical internalisation (PCI): a further development of photodynamic therapy for the treatment of skin cancer]
    Pål Johansen
    Dermatologische Klinik, Universitatsspital Zurich
    Praxis (Bern 1994) 99:1423-8. 2010
    ..Preliminary results from this trial suggest that PCI seems to be a promising treatment...
  23. doi request reprint Phototherapy with UVB narrowband, UVA/UVBnb, and UVA1 differentially impacts serum 25-hydroxyvitamin-D3
    Laurence Feldmeyer
    Department of Dermatology, University Hospital Zurich, Zurich, Switzerland Electronic address
    J Am Acad Dermatol 69:530-6. 2013
    ..Ultraviolet (UV) B radiation increases serum 25-hydroxyvitamin-D3 [25(OH)D], but the influence of UVA1 and UVA/narrowband UVB (UVBnb) phototherapy on serum vitamin D is unknown...
  24. pmc The expression levels of microRNA-361-5p and its target VEGFA are inversely correlated in human cutaneous squamous cell carcinoma
    Alexander Kanitz
    Institute of Pharmaceutical Sciences, ETH Zurich, Zurich, Switzerland
    PLoS ONE 7:e49568. 2012
    ..Importantly, we found that miR-361-5p levels are inversely correlated with VEGFA expression in SCC and in healthy skin, indicating that miR-361-5p could play a role in cancers...
  25. ncbi request reprint Weight of decision-making impairs clinical assessment of melanocytic lesions
    Tamara Gächter
    Department of Dermatology, University Hospital of Zurich, Zurich, Switzerland
    J Cutan Med Surg 11:9-18. 2007
    ..We studied the weight of decision-making on clinical assessment of melanocytic lesions judging benign, atypical, and malignant lesions; common mistakes; and total removal rates, comparing dermatologists with nondermatologists...
  26. doi request reprint Skin cancer in organ transplant recipients
    Werner Kempf
    Kempf and Pfaltz Histological Diagnostics, Zurich, Switzerland
    Pathobiology 80:302-9. 2013
    ..This review discusses the clinical and histopathological aspects of skin cancers in OTR, the impact of dermatopathological analysis on prognosis and the understanding of the pathogenesis of these neoplasms. ..
  27. pmc Trichophyton rubrum-induced Majocchi's Granuloma in a heart transplant recipient. A therapeutic challenge
    Urs C Steiner
    Department of Dermatology, University Hospital, Zurich, Switzerland
    J Dermatol Case Rep 6:70-2. 2012
    ..Itraconazole is an anti-fungal compound used for the treatment of infections of the skin, nails and mucous membranes...
  28. doi request reprint Phototoxic and photoallergic cutaneous drug reactions
    Martin Glatz
    Department of Dermatology, University Hospital Zurich, Zurich, Switzerland
    Chem Immunol Allergy 97:167-79. 2012
    ..Mainstays of treatment are the withdrawal of the culprit drug, and avoidance of sunlight by wearing protective clothing and broadband sunscreens with UVA filters...
  29. doi request reprint Pictorial Representation of Illness and Self Measure (PRISM): A novel visual instrument to measure quality of life in dermatological inpatients
    Beda Mühleisen
    Department of Dermatology, University Hospital Zurich, Switzerland
    Arch Dermatol 145:774-80. 2009
    ....
  30. doi request reprint Ecthyma-gangrenosum-like bullous pemphigoid
    Jana Geiss Steiner
    Dermatology Department, University Hospital, Zurich, Switzerland
    Dermatology 221:142-8. 2010
    ..In summary, we propose this combination of truncal ecthyma-gangrenosum-like lesions with bacterial colonization in the context of older age and immobility as a clinically distinct presentation or variant of BP...
  31. ncbi request reprint Cancer/testis antigen MAGE-A4 expression pattern differs in epithelial skin tumors of organ-transplant recipients and immunocompetent patients
    Beda Muehleisen
    Department of Dermatology, University Hospital Zurich, Zurich, Switzerland
    J Cutan Pathol 34:1-6. 2007
    ..We were interested in the frequency and distribution of MAGE-A4 in epithelial skin tumors of OTR and immunocompetent patients...
  32. doi request reprint Herpes simplex virus reactivation as a complication of photodynamic therapy
    Stephan Nobbe
    Department of Dermatology, University Hospital Zurich, Zurich, Switzerland
    Photodermatol Photoimmunol Photomed 27:51-2. 2011
    ..Further applications of PDT under antiviral prophylaxis were well tolerated by our patient, with no further herpetic reactivation and successful treatment of actinic keratoses...
  33. doi request reprint Not all intravenous immunoglobulin preparations are equally well tolerated
    Laurence Feldmeyer
    Department of Dermatology, University Hospital Zurich, Switzerland
    Acta Derm Venereol 90:494-7. 2010
    ..If a reduction in the infusion rate does not minimize side-effects, one should consider switching the IVIG formulation...
  34. doi request reprint Changing delayed-type sensitizations to the baseline series allergens over a decade at the Zurich University Hospital
    Manon Janach
    Department of Dermatology, University Hospital of Zurich, Switzerland
    Contact Dermatitis 63:42-8. 2010
    ..Patch testing detects delayed-type sensitizations and may show changes in prevalence over time...