C Hock

Summary

Affiliation: University of Basel
Country: Switzerland

Publications

  1. ncbi request reprint Decrease in parietal cerebral hemoglobin oxygenation during performance of a verbal fluency task in patients with Alzheimer's disease monitored by means of near-infrared spectroscopy (NIRS)--correlation with simultaneous rCBF-PET measurements
    C Hock
    Psychiatrische Universitätsklinik PUK, Basel, Switzerland
    Brain Res 755:293-303. 1997
  2. ncbi request reprint Cerebrospinal fluid levels of amyloid precursor protein and amyloid beta-peptide in Alzheimer's disease and major depression - inverse correlation with dementia severity
    C Hock
    Department of Psychiatry, University of Basel, Switzerland
    Eur Neurol 39:111-8. 1998
  3. ncbi request reprint Alterations in trk A, trk B and trk C receptor immunoreactivities in parietal cortex and cerebellum in Alzheimer's disease
    E Savaskan
    Department of Psychiatry, University of Basel, Switzerland
    Eur Neurol 44:172-80. 2000
  4. ncbi request reprint Histological markers in nasal mucosa of patients with Alzheimer's disease
    C Hock
    Department of Psychiatry, University of Basel, Switzerland
    Eur Neurol 40:31-6. 1998
  5. ncbi request reprint Decreased trkA neurotrophin receptor expression in the parietal cortex of patients with Alzheimer's disease
    C Hock
    Department of Psychiatry PUK, University of Basel, Switzerland
    Neurosci Lett 241:151-4. 1998
  6. ncbi request reprint Alzheimer's disease, depression and normal ageing: merit of simple psychomotor and visuospatial tasks
    M Hofman
    Department of Psychiatry, University of Basel, Basel, Switzerland
    Int J Geriatr Psychiatry 15:31-9. 2000
  7. ncbi request reprint Cortical alterations of angiotensin converting enzyme, angiotensin II and AT1 receptor in Alzheimer's dementia
    E Savaskan
    Department of Psychiatry, University of Basel, Wilhelm Klein Str 27, CH 4054, Basel, Switzerland
    Neurobiol Aging 22:541-6. 2001
  8. ncbi request reprint Rapid cortical hemoglobin deoxygenation after heroin and methadone injection in humans: a preliminary report
    R Stohler
    Department of Psychiatry, University of Zurich, Switzerland
    Drug Alcohol Depend 57:23-8. 1999
  9. ncbi request reprint Mercury induces cell cytotoxicity and oxidative stress and increases beta-amyloid secretion and tau phosphorylation in SHSY5Y neuroblastoma cells
    G Olivieri
    Neurobiology Laboratory, Psychiatric University Hospital, Basel, Switzerland
    J Neurochem 74:231-6. 2000
  10. ncbi request reprint Risk factors and differential diagnosis of Alzheimer's disease
    F Muller-Spahn
    Psychiatrische Universitatsklinik, Basel, Switzerland
    Eur Arch Psychiatry Clin Neurosci 249:37-42. 1999

Collaborators

Detail Information

Publications12

  1. ncbi request reprint Decrease in parietal cerebral hemoglobin oxygenation during performance of a verbal fluency task in patients with Alzheimer's disease monitored by means of near-infrared spectroscopy (NIRS)--correlation with simultaneous rCBF-PET measurements
    C Hock
    Psychiatrische Universitätsklinik PUK, Basel, Switzerland
    Brain Res 755:293-303. 1997
    ....
  2. ncbi request reprint Cerebrospinal fluid levels of amyloid precursor protein and amyloid beta-peptide in Alzheimer's disease and major depression - inverse correlation with dementia severity
    C Hock
    Department of Psychiatry, University of Basel, Switzerland
    Eur Neurol 39:111-8. 1998
    ..Thus, CSF levels of Abeta are not useful for the differentiation of AD from major depression. However, CSF levels of Abeta reflect the severity of dementia and may be useful as biological markers of the stage of the disease...
  3. ncbi request reprint Alterations in trk A, trk B and trk C receptor immunoreactivities in parietal cortex and cerebellum in Alzheimer's disease
    E Savaskan
    Department of Psychiatry, University of Basel, Switzerland
    Eur Neurol 44:172-80. 2000
    ..In addition, cerebellar Purkinje cells revealed a distinct immunoreactivity for trk C both in control and AD cases, suggesting trk C may be important in the maintenance of these cells in the aged brain...
  4. ncbi request reprint Histological markers in nasal mucosa of patients with Alzheimer's disease
    C Hock
    Department of Psychiatry, University of Basel, Switzerland
    Eur Neurol 40:31-6. 1998
    ..These results are consistent with other reports showing that cytoskeletal changes and tau pathology in the olfactory epithelium are not primary (or specific) features of AD and may occur predominantly in late stages of the disease...
  5. ncbi request reprint Decreased trkA neurotrophin receptor expression in the parietal cortex of patients with Alzheimer's disease
    C Hock
    Department of Psychiatry PUK, University of Basel, Switzerland
    Neurosci Lett 241:151-4. 1998
    ..These results reveal a central specific role of the high affinity NGF receptor during neurodegeneration in AD...
  6. ncbi request reprint Alzheimer's disease, depression and normal ageing: merit of simple psychomotor and visuospatial tasks
    M Hofman
    Department of Psychiatry, University of Basel, Basel, Switzerland
    Int J Geriatr Psychiatry 15:31-9. 2000
    ..The purpose was to investigate the discriminative value of simple psychomotor and visuospatial tasks that were implemented in a computer-assisted test battery...
  7. ncbi request reprint Cortical alterations of angiotensin converting enzyme, angiotensin II and AT1 receptor in Alzheimer's dementia
    E Savaskan
    Department of Psychiatry, University of Basel, Wilhelm Klein Str 27, CH 4054, Basel, Switzerland
    Neurobiol Aging 22:541-6. 2001
    ..In addition, a prominent perivascular ACE and angiotensin II immunoreactivity surrounding some cortical vessels in aged controls and AD patients points to an underlying microvascular pathology in the process of neurodegeneration...
  8. ncbi request reprint Rapid cortical hemoglobin deoxygenation after heroin and methadone injection in humans: a preliminary report
    R Stohler
    Department of Psychiatry, University of Zurich, Switzerland
    Drug Alcohol Depend 57:23-8. 1999
    ..Saline had no effects. Opioid-induced acute deoxygenation of cortical hemoglobin is most likely associated with respiratory depression. Thorough medical monitoring is strongly recommended in intravenous opioid maintenance treatments...
  9. ncbi request reprint Mercury induces cell cytotoxicity and oxidative stress and increases beta-amyloid secretion and tau phosphorylation in SHSY5Y neuroblastoma cells
    G Olivieri
    Neurobiology Laboratory, Psychiatric University Hospital, Basel, Switzerland
    J Neurochem 74:231-6. 2000
    ..001), whereas melatonin preincubation reduced the phosphorylation to control values. These results indicate that mercury may play a role in pathophysiological mechanisms of AD...
  10. ncbi request reprint Risk factors and differential diagnosis of Alzheimer's disease
    F Muller-Spahn
    Psychiatrische Universitatsklinik, Basel, Switzerland
    Eur Arch Psychiatry Clin Neurosci 249:37-42. 1999
    ..Various genetic and non-genetic risk factors play a role in influencing age of onset and disease progression...
  11. ncbi request reprint Cytokines and neurotrophins interact in normal and diseased states
    U Otten
    Department of Physiology, University of Basel, Vesalgasse 1, CH 4051 Basel, Switzerland
    Ann N Y Acad Sci 917:322-30. 2000
    ..This indicates that the IL-6 system mediates a local supply of NTs that participate in diverse CNS functions, such as protection of neurons from insults, neuronal survival, and neuroimmune responses...
  12. ncbi request reprint Dependence of cerebrospinal fluid Tau protein levels on apolipoprotein E4 allele frequency in patients with Alzheimer's disease
    S Golombowski
    Department of Psychiatry PUK, University of Basel, Switzerland
    Neurosci Lett 225:213-5. 1997
    ..71, P = 0.007). This finding may be in agreement with reports of a lesser binding of apoE4 to Tau, compared to apoE2 and apoE3, resulting in higher levels of unbound Tau in CSF...