Uwe Guth

Summary

Affiliation: University of Basel
Country: Switzerland

Publications

  1. doi request reprint Primary and secondary distant metastatic breast cancer: two sides of the same coin
    Uwe Guth
    University Hospital Basel UHB, Department of Gynecology and Obstetrics, Spitalstrasse 21, CH 4031 Basel, Switzerland Cantonal Hospital Winterthur, Department of Gynecology and Obstetrics, Brauerstrasse 15, CH 8401 Winterthur, Switzerland Breast Center SenoSuisse, Brauerstrasse 15, CH 8401 Winterthur, Switzerland Electronic address
    Breast 23:26-32. 2014
  2. doi request reprint [Development of overweight and obesity in breast cancer patients and its significance for diagnosis and clinical management: results of the Basel Breast Cancer Database 1990-2009]
    Uwe Guth
    Departement für Geburtshilfe und Gynäkologie, Brustzentrum SenoSuisse und Universitätsspital Basel, Frauenklinik
    Praxis (Bern 1994) 102:473-80. 2013
  3. doi request reprint The post ACOSOG Z0011 era: does our new understanding of breast cancer really change clinical practice?
    U Guth
    University Hospital Basel UHB, Department of Gynecology and Obstetrics, Spitalstrasse 21, CH 4031 Basel, Switzerland
    Eur J Surg Oncol 38:645-50. 2012
  4. doi request reprint Clinical outcomes and patterns of severe late toxicity in the era of chemo-radiation for cervical cancer
    Uwe Guth
    Department of Gynaecological Oncology, North London Gynaecological Cancer Network, University College London Hospital UCLH, 250 Euston Road, London, NW1 2 PG, UK
    Arch Gynecol Obstet 285:1703-11. 2012
  5. doi request reprint Increasing rates of contralateral prophylactic mastectomy - a trend made in USA?
    U Guth
    University Hospital Basel, Department of Gynecology and Obstetrics, Spitalstrasse 21, CH 4031 Basel, Switzerland
    Eur J Surg Oncol 38:296-301. 2012
  6. doi request reprint Compliance and persistence of endocrine adjuvant breast cancer therapy
    Uwe Guth
    Department of Gynecology and Obstetrics, University Hospital Basel, Spitalstrasse 21, 4031 Basel, Switzerland
    Breast Cancer Res Treat 131:491-9. 2012
  7. doi request reprint Suicide in breast cancer patients: an individual-centered approach provides insight beyond epidemiology
    Uwe Guth
    University Hospital Basel, Department of Gynecology and Obstetrics, Switzerland
    Acta Oncol 50:1037-44. 2011
  8. doi request reprint Drug switch because of treatment-related adverse side effects in endocrine adjuvant breast cancer therapy: how often and how often does it work?
    Uwe Guth
    Department of Gynecology and Obstetrics, University Hospital Basel, Spitalstrasse 21, 4031 Basel, Switzerland
    Breast Cancer Res Treat 129:799-807. 2011
  9. ncbi request reprint Correlation and significance of histopathological and clinical features in breast cancer with skin involvement (T4b)
    Uwe Guth
    Department of Gynecology and Obstetrics, University Hospital Basel UHB, CH 4031 Basel, Switzerland
    Hum Pathol 37:264-71. 2006
  10. doi request reprint Breast cancer in women 80 years of age and older: a comprehensive analysis of an underreported entity
    Marcus Vetter
    University Hospital Basel UHB, Breast Center, Basel, Switzerland
    Acta Oncol 52:57-65. 2013

Collaborators

Detail Information

Publications32

  1. doi request reprint Primary and secondary distant metastatic breast cancer: two sides of the same coin
    Uwe Guth
    University Hospital Basel UHB, Department of Gynecology and Obstetrics, Spitalstrasse 21, CH 4031 Basel, Switzerland Cantonal Hospital Winterthur, Department of Gynecology and Obstetrics, Brauerstrasse 15, CH 8401 Winterthur, Switzerland Breast Center SenoSuisse, Brauerstrasse 15, CH 8401 Winterthur, Switzerland Electronic address
    Breast 23:26-32. 2014
    ....
  2. doi request reprint [Development of overweight and obesity in breast cancer patients and its significance for diagnosis and clinical management: results of the Basel Breast Cancer Database 1990-2009]
    Uwe Guth
    Departement für Geburtshilfe und Gynäkologie, Brustzentrum SenoSuisse und Universitätsspital Basel, Frauenklinik
    Praxis (Bern 1994) 102:473-80. 2013
    ..Galler risk score. In most therapy modes, patients with increasing BMI demonstrated a higher compliance and persistence to adjuvant therapies...
  3. doi request reprint The post ACOSOG Z0011 era: does our new understanding of breast cancer really change clinical practice?
    U Guth
    University Hospital Basel UHB, Department of Gynecology and Obstetrics, Spitalstrasse 21, CH 4031 Basel, Switzerland
    Eur J Surg Oncol 38:645-50. 2012
    ..The aim of the current study was to assess the potential impact of Z0011 on clinical practice by testing the applicability of its criteria to a European patient population...
  4. doi request reprint Clinical outcomes and patterns of severe late toxicity in the era of chemo-radiation for cervical cancer
    Uwe Guth
    Department of Gynaecological Oncology, North London Gynaecological Cancer Network, University College London Hospital UCLH, 250 Euston Road, London, NW1 2 PG, UK
    Arch Gynecol Obstet 285:1703-11. 2012
    ..We introduce a revised concept of reporting treatment failure...
  5. doi request reprint Increasing rates of contralateral prophylactic mastectomy - a trend made in USA?
    U Guth
    University Hospital Basel, Department of Gynecology and Obstetrics, Spitalstrasse 21, CH 4031 Basel, Switzerland
    Eur J Surg Oncol 38:296-301. 2012
    ..We present the first European study reporting CPM rates in an unselected cohort of patients with BC...
  6. doi request reprint Compliance and persistence of endocrine adjuvant breast cancer therapy
    Uwe Guth
    Department of Gynecology and Obstetrics, University Hospital Basel, Spitalstrasse 21, 4031 Basel, Switzerland
    Breast Cancer Res Treat 131:491-9. 2012
    ..Efforts should be made to make sure that all physicians, above all general practitioners, who are involved in BC treatment, are provided with current knowledge as to guarantee an optimal patient management...
  7. doi request reprint Suicide in breast cancer patients: an individual-centered approach provides insight beyond epidemiology
    Uwe Guth
    University Hospital Basel, Department of Gynecology and Obstetrics, Switzerland
    Acta Oncol 50:1037-44. 2011
    ..None of the studies have been carried out in a prospective manner and none reported suicide rates from a country in which physician-assisted suicide (PAS) is legal...
  8. doi request reprint Drug switch because of treatment-related adverse side effects in endocrine adjuvant breast cancer therapy: how often and how often does it work?
    Uwe Guth
    Department of Gynecology and Obstetrics, University Hospital Basel, Spitalstrasse 21, 4031 Basel, Switzerland
    Breast Cancer Res Treat 129:799-807. 2011
    ..In cases when therapy-related side effects occur, a drug switch is a promising step to further improve persistence and, by doing so, the outcome of breast cancer patients...
  9. ncbi request reprint Correlation and significance of histopathological and clinical features in breast cancer with skin involvement (T4b)
    Uwe Guth
    Department of Gynecology and Obstetrics, University Hospital Basel UHB, CH 4031 Basel, Switzerland
    Hum Pathol 37:264-71. 2006
    ..Our results challenge the validity of the TNM rules and recommendations concerning T4b breast cancer because it leads, in the majority of cases, to tumors of comparable extent and prognosis being placed in different categories...
  10. doi request reprint Breast cancer in women 80 years of age and older: a comprehensive analysis of an underreported entity
    Marcus Vetter
    University Hospital Basel UHB, Breast Center, Basel, Switzerland
    Acta Oncol 52:57-65. 2013
    ..Approximately 10% of breast cancer (BC) patients are over the age of 80. We present the first comprehensive review on this particular group of patients...
  11. doi request reprint Impact of body mass index on compliance and persistence to adjuvant breast cancer therapy
    Seraina Margaretha Schmid
    University Hospital Basel, Department of Gynecology and Obstetrics, Spitalstrasse 21, CH 4031 Basel, Switzerland
    Breast 21:487-92. 2012
    ..In most therapy modes, patients with increasing BMI demonstrated a higher motivation and perseverance to the recommended treatment...
  12. ncbi request reprint A new approach in breast cancer with non-inflammatory skin involvement
    Uwe Guth
    Department of Gynecology and Obstetrics, University Hospital Basel, UHB, Spitalstrasse 21, CH 4031, Basel, Switzerland
    Acta Oncol 45:576-83. 2006
    ..The highest T category, or Stage III, is not the appropriate classification for a considerable number of patients having this clinicopathologic entity...
  13. doi request reprint Breast cancer with non-inflammatory skin involvement: current data on an underreported entity and its problematic classification
    Uwe Guth
    University Hospital Basel, Department of Gynecology and Obstetrics, Spitalstrasse 21, Basel, Switzerland
    Breast 19:59-64. 2010
    ..Our proposal is to eliminate these tumours from the T4 category and to classify them simply by size (T1-3). Due to its prognostic significance, NISI should be indicated by an optional descriptor (e.g. S1)...
  14. doi request reprint Success and failure of primary medical, nonoperative management in breast cancer
    Seraina Margaretha Schmid
    Department of Gynecology and Obstetrics, University Hospital Basel UHB, Basel, Switzerland
    Ann Surg Oncol 18:2166-72. 2011
    ..We evaluated rates of and predicting factors for success and failure of this therapy approach...
  15. ncbi request reprint T4 category revision enhances the accuracy and significance of stage III breast cancer
    Uwe Guth
    Department of Gynecology and Obstetrics, University Hospital Basel, Basel, Switzerland
    Cancer 106:2569-75. 2006
    ..In the current study, the authors evaluated how implementation of this proposal will affect Stage III noninflammatory breast cancer...
  16. doi request reprint Is the current concept of recurrent ovarian carcinoma as a chronic disease also applicable in platinum resistant patients?
    Uwe Guth
    Department of Gynecology and Obstetrics, University Hospital Basel UHB, Spitalstrasse 21, 4031, Basel, Switzerland
    Arch Gynecol Obstet 281:339-44. 2010
    ..We evaluated whether it is justifiable to also apply this concept to the treatment of platinum resistant patients with their known poor prognosis and short overall survival (OS)...
  17. doi request reprint Systemic therapy developments and their effects regarding the current concept of recurrent ovarian carcinoma as a chronic disease
    Uwe Guth
    Department of Gynecology and Obstetrics, University Hospital Basel, Spitalstrasse 21, 4031 Basel, Switzerland
    Arch Gynecol Obstet 280:719-24. 2009
    ..To demonstrate how the current concept of recurrent ovarian carcinoma (ROC) as a chronic disease resulted in developments in the systemic treatment strategies and outcome over time...
  18. doi request reprint Three-dimensional pathological size assessment in primary breast carcinoma
    Uwe Guth
    Department of Gynecology and Obstetrics, University Hospital Basel, Basel, Switzerland
    Breast Cancer Res Treat 116:257-62. 2009
    ....
  19. doi request reprint Young women with breast cancer: how many are actually candidates for fertility preservation?
    Rebecca Moffat
    Clinic for Gynecologic Endocrinology and Reproductive Medicine, Women s Hospital, University Hospital Basel UHB, Spitalstrasse 21, 4031, Basel, Switzerland
    Arch Gynecol Obstet 286:1521-7. 2012
    ..We aimed to identify how many patients are actually potential candidates for FP and how many patients might consequently use their cryopreserved gametes to achieve pregnancy...
  20. doi request reprint Menopausal state in breast cancer: how reliable is the data?
    Rebecca Elizabeth Moffat
    Department of Gynecology and Obstetrics, University Hospital Basel, Basel, Switzerland
    Clin Breast Cancer 11:390-4. 2011
    ..The scope of uncertainties regarding the recording of the menopausal state in a cohort of patients with breast cancer is evaluated...
  21. ncbi request reprint T4 breast cancer under closer inspection: a case for revision of the TNM classification
    Uwe Guth
    University Hospital Basel, Department of Gynecology and Obstetrics, Spitalstrasse 21, CH 4031 Basel, Switzerland
    Breast 16:625-36. 2007
    ..Through the revision of the T4 category, the definitions and guidelines of inflammatory breast carcinoma should be adapted to the internationally accepted nomenclature...
  22. doi request reprint Tumor size and detection in breast cancer: Self-examination and clinical breast examination are at their limit
    Uwe Guth
    University Hospital Basel, Department of Gynecology and Obstetrics, Spitalstrasse 21, CH 4031 Basel, Switzerland
    Cancer Detect Prev 32:224-8. 2008
    ..This study investigates to what extent tumor detection methods in breast cancer have changed and how this has influenced tumor size at initial diagnosis...
  23. doi request reprint Impact of breast cancer family history on tumor detection and tumor size in women newly-diagnosed with invasive breast cancer
    Fabienne Dominique Schwab
    Department of Gynecology and Obstetrics, University Hospital Basel UHB, Spitalstrasse 21, 4031, Basel, Switzerland
    Fam Cancer 13:99-107. 2014
    ..Women with a positive FH generally use mammography screening more often and perceive changes in the breast earlier than women without such history. The increased awareness of BC risk decreases if the relationship is more distant. ..
  24. ncbi request reprint Metastatic patterns at autopsy in patients with ovarian carcinoma
    Uwe Guth
    Department of Gynecology and Obstetrics, University Hospital Basel, Basel, Switzerland
    Cancer 110:1272-80. 2007
    ..The objective of the current study was to determine the frequency and sites of metastases in patients with ovarian cancer with particular attention to the clinical course and therapy...
  25. pmc Differential pattern and prognostic significance of CD4+, FOXP3+ and IL-17+ tumor infiltrating lymphocytes in ductal and lobular breast cancers
    Raoul Droeser
    Department of Surgery, University Hospital Basel, Switzerland
    BMC Cancer 12:134. 2012
    ....
  26. doi request reprint Distant metastatic breast cancer as an incurable disease: a tenet with a need for revision
    Uwe Guth
    Department of Gynecology and Obstetrics, University Hospital Basel UHB, Spitalstrasse 21, Basel CH 4031, Switzerland
    Cancer J 15:81-6. 2009
    ..Our study evaluates the rate and characteristics of long-term survivors based on a nonselective study cohort...
  27. doi request reprint High IL-17-positive tumor immune cell infiltration is indicative for chemosensitivity of ovarian carcinoma
    Raoul A Droeser
    Department of Surgery, University Hospital Basel, Spitalstrasse 21, 4031 Basel, Switzerland
    J Cancer Res Clin Oncol 139:1295-302. 2013
    ..In this study, we evaluated the predictive value of IL-17- and FOXP3-positive tumor immune cell infiltration (TICI) for response to chemotherapy in ovarian carcinoma...
  28. doi request reprint Eligibility, compliance and persistence of extended adjuvant endocrine therapy for breast cancer
    Mary E Myrick
    University Hospital Basel, Department of Gynecology and Obstetrics, Basel, Switzerland
    Acta Oncol 51:247-53. 2012
    ..In this study we evaluated eligibility, compliance and persistence of extended adjuvant endocrine BC therapy...
  29. doi request reprint The use of adjuvant endocrine breast cancer therapy in the oldest old
    Uwe Guth
    University Hospital Basel UHB, Department of Gynecology and Obstetrics, Spitalstrasse 21, CH 4031 Basel, Switzerland Cantonal Hospital Winterthur CHW, Department of Gynecology and Obstetrics, Brauerstrasse 15, CH 8401 Winterthur, Switzerland Breast Center SenoSuisse, Brauerstrasse 15, CH 8401 Winterthur, Switzerland Electronic address
    Breast 22:863-8. 2013
    ....
  30. ncbi request reprint Breast carcinoma with noninflammatory skin involvement (T4b): time to abandon an historic relic from the TNM classification
    Uwe Guth
    Department of Gynecology and Obstetrics, University Hospital Basel, Basel, Switzerland
    Cancer 104:1862-70. 2005
    ....
  31. pmc Deletion of the inhibitor of growth 4 (ING4) tumor suppressor gene is prevalent in human epidermal growth factor 2 (HER2)-positive breast cancer
    Coya Tapia
    Institute for Pathology, University Hospital Basel, Schonbeinstrasse 40, 4103 Basel, Switzerland
    Hum Pathol 42:983-90. 2011
    ..These results sustain the view that ING4 is a tumor suppressor in breast cancer and suggest that ING4 deletion may contribute to the pathogenesis of HER2-positive breast cancer...
  32. doi request reprint Strictly defined familial male breast cancer
    Uwe Guth
    Division of Gynecologic Oncology, Department of Gynecology and Obstetrics, University Hospital Basel UHB, Basel, Switzerland
    Fam Cancer 10:73-7. 2011
    ..This approach emphasizes familial MBC as a distinct entity and not only as a variant of female breast cancer...