Research Topics
Genomes and GenesSpecies | Jobst GreeveSummaryAffiliation: University Hospital Country: Switzerland Publications
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Detail Information
Publications
Hepatitis B: modern concepts in pathogenesis--APOBEC3 cytidine deaminases as effectors in innate immunity against the hepatitis B virusMarianne Bonvin
Department of Clinical Research, Switzerland, University of Berne, Berne, Switzerland
Curr Opin Infect Dis 21:298-303. 2008..This review focuses on the effects of APOBEC3 enzymes on the pararetrovirus hepatitis B virus...
Expression of activation-induced cytidine deaminase in human B-cell non-Hodgkin lymphomasJobst Greeve
Zentrum fur Innere Medizin, Medizinische Klinik I, Universitatsklinikum Hamburg Eppendorf, Germany
Blood 101:3574-80. 2003..This constitutive expression of AID may promote illegitimate DNA recombinations and somatic mutations in B-NHL...
Reduced expression and increased CpG dinucleotide methylation of the rat APOBEC-1 promoter in transgenic rabbitsFrank Apostel
Klinik und Poliklinik für Innere Medizin, Universitatsklinikum Hamburg Eppendorf, Martinistrasse 52, Germany
Biochim Biophys Acta 1577:384-94. 2002..Thus, the weak proximal rat APOBEC-1 promoter appears to be down-regulated in the rabbit and may be species-specific...
Reconstitution of mRNA editing in yeast using a Gal4-apoB-Gal80 fusion transcript as the selectable markerHeinrich Lellek
, Kernklinik und Poliklinik, , Martinistrasse 52, 20246 Hamburg, Germany
J Biol Chem 277:23638-44. 2002..The Gal4-Gal80 system is analogous to the two-hybrid assay and may have broader applications for the study of other mRNA processing reactions...
The cytidine deaminases AID and APOBEC-1 exhibit distinct functional properties in a novel yeast selectable systemKristina Krause
Department of Clinical Research, University of Berne, Berne, Switzerland
Mol Immunol 43:295-307. 2006..In contrast to APOBEC-1, AID alone does not exhibit an intrinsic specificity for its target sequences...
Gene structure and expression of the mouse APOBEC-1 complementation factor: multiple transcriptional initiation sites and a spliced variant with a premature stop translation codonStefan Dür
Department of General Internal Medicine, Inselspital University Hospital Bern, CH 3010 Bern, Switzerland
Biochim Biophys Acta 1680:11-23. 2004....
Authors reply to I.B. Rogozin and Y.I. Pavlov: 'The cytidine deaminase AID exhibits similar functional properties in yeast and mammals'Kristina Krause
Mol Immunol 43:1924-6. 2006
Interferon-inducible expression of APOBEC3 editing enzymes in human hepatocytes and inhibition of hepatitis B virus replicationMarianne Bonvin
Department of Clinical Research, University Hospital Berne, Switzerland
Hepatology 43:1364-74. 2006..In conclusion, the editing enzymes A3B(L), A3F, and most markedly A3G, which are expressed in liver and up-regulated by IFN-alpha in hepatocytes, are candidates to contribute to the noncytolytic clearance of HBV...
Effects of point mutations in the cytidine deaminase domains of APOBEC3B on replication and hypermutation of hepatitis B virus in vitroMarianne Bonvin
Department of Clinical Research, University Hospital Berne, Switzerland
J Gen Virol 88:3270-4. 2007....
