G Gold

Summary

Affiliation: University Hospital
Country: Switzerland

Publications

  1. ncbi request reprint [Assessment of behavior in non-psychiatric settings: use of a simple and reliable method]
    Gabriel Gold
    Service de Geriatrie, HUG, hôpital des Trois Chêne, 3, chemin du Pont Bochet, 1226 Thônex Genève
    Rev Med Suisse 8:2119-21. 2012
  2. ncbi request reprint Cognitive consequences of thalamic, basal ganglia, and deep white matter lacunes in brain aging and dementia
    Gabriel Gold
    Department of Geriatrics, HUG Belle Idée, University of Geneva School of Medicine, Geneva, Switzerland
    Stroke 36:1184-8. 2005
  3. ncbi request reprint Vascular dementia: a diagnostic challenge
    Gabriel Gold
    HUG, Belle Idee, Department of Geriatrics, Geneva, Switzerland
    Int Psychogeriatr 15:111-4. 2003
  4. ncbi request reprint Sorting out the clinical consequences of ischemic lesions in brain aging: a clinicopathological approach
    Gabriel Gold
    Department of Geriatrics, University of Geneva School of Medicine, Geneva, Switzerland
    J Neurol Sci 257:17-22. 2007
  5. ncbi request reprint Identification of Alzheimer and vascular lesion thresholds for mixed dementia
    Gabriel Gold
    Department of Geriatrics, University of Geneva School of Medicine, Geneva
    Brain 130:2830-6. 2007
  6. doi request reprint Defining the neuropathological background of vascular and mixed dementia and comparison with magnetic resonance imaging findings
    Gabriel Gold
    Department of Geriatrics and Rehabilitation, Geneva University School of Medicine and Geneva University Hospitals, Thonex, Geneva, Switzerland
    Front Neurol Neurosci 24:86-94. 2009
  7. doi request reprint Dementia with Lewy bodies: clinical diagnosis and therapeutic approach
    Gabriel Gold
    Geneva University School of Medicine and Geneva University Hospitals, Geneva, Switzerland
    Front Neurol Neurosci 24:107-13. 2009
  8. ncbi request reprint Clinicopathological validation study of four sets of clinical criteria for vascular dementia
    Gabriel Gold
    Department of Geriatrics, University Hospital of Geneva, Switzerland
    Am J Psychiatry 159:82-7. 2002
  9. ncbi request reprint Clinical validity of Braak neuropathological staging in the oldest-old
    G Gold
    Department of Geriatrics, University Hospitals of Geneva, Thonex Geneve, Switzerland
    Acta Neuropathol 99:579-82; discussion 583-4. 2000
  10. ncbi request reprint Working memory load-related electroencephalographic parameters can differentiate progressive from stable mild cognitive impairment
    P Missonnier
    Clinical Neurophysiology and Neuroimaging Unit, Division of Neuropsychiatry, Department of Psychiatry, University Hospitals of Geneva, 2 Chemin du Petit Bel Air, 1225 Chene Bourg, Geneva, Switzerland
    Neuroscience 150:346-56. 2007

Detail Information

Publications73

  1. ncbi request reprint [Assessment of behavior in non-psychiatric settings: use of a simple and reliable method]
    Gabriel Gold
    Service de Geriatrie, HUG, hôpital des Trois Chêne, 3, chemin du Pont Bochet, 1226 Thônex Genève
    Rev Med Suisse 8:2119-21. 2012
    ..This article describes the development of a French version of a simple and reliable scale that is easy to use in somatic settings to foster clear and objective communication around this symptomatology...
  2. ncbi request reprint Cognitive consequences of thalamic, basal ganglia, and deep white matter lacunes in brain aging and dementia
    Gabriel Gold
    Department of Geriatrics, HUG Belle Idée, University of Geneva School of Medicine, Geneva, Switzerland
    Stroke 36:1184-8. 2005
    ....
  3. ncbi request reprint Vascular dementia: a diagnostic challenge
    Gabriel Gold
    HUG, Belle Idee, Department of Geriatrics, Geneva, Switzerland
    Int Psychogeriatr 15:111-4. 2003
    ..Further studies are needed to develop better performing criteria that could lead to a broad consensus on the clinical diagnosis of vascular and mixed dementia...
  4. ncbi request reprint Sorting out the clinical consequences of ischemic lesions in brain aging: a clinicopathological approach
    Gabriel Gold
    Department of Geriatrics, University of Geneva School of Medicine, Geneva, Switzerland
    J Neurol Sci 257:17-22. 2007
    ..Vascular lesions are particularly common in the aged brain. However, it is still unclear whether all such lesions affect cognition...
  5. ncbi request reprint Identification of Alzheimer and vascular lesion thresholds for mixed dementia
    Gabriel Gold
    Department of Geriatrics, University of Geneva School of Medicine, Geneva
    Brain 130:2830-6. 2007
    ..Proposed thresholds for vascular and degenerative lesions predict the presence of dementia with great accuracy and provide a basis for distinguishing pure vascular dementia or AD from mixed cases...
  6. doi request reprint Defining the neuropathological background of vascular and mixed dementia and comparison with magnetic resonance imaging findings
    Gabriel Gold
    Department of Geriatrics and Rehabilitation, Geneva University School of Medicine and Geneva University Hospitals, Thonex, Geneva, Switzerland
    Front Neurol Neurosci 24:86-94. 2009
    ..Vascular scores have been proposed that can be combined with well-established classifications of Alzheimer's disease (AD) pathology to distinguish mixed dementias from pure AD and pure VaD...
  7. doi request reprint Dementia with Lewy bodies: clinical diagnosis and therapeutic approach
    Gabriel Gold
    Geneva University School of Medicine and Geneva University Hospitals, Geneva, Switzerland
    Front Neurol Neurosci 24:107-13. 2009
    ..Physicians who care for older people should have a heightened awareness of this entity in order to diagnose it early, avoid mistaking it for delirium and initiate appropriate treatment...
  8. ncbi request reprint Clinicopathological validation study of four sets of clinical criteria for vascular dementia
    Gabriel Gold
    Department of Geriatrics, University Hospital of Geneva, Switzerland
    Am J Psychiatry 159:82-7. 2002
    ....
  9. ncbi request reprint Clinical validity of Braak neuropathological staging in the oldest-old
    G Gold
    Department of Geriatrics, University Hospitals of Geneva, Thonex Geneve, Switzerland
    Acta Neuropathol 99:579-82; discussion 583-4. 2000
    ....
  10. ncbi request reprint Working memory load-related electroencephalographic parameters can differentiate progressive from stable mild cognitive impairment
    P Missonnier
    Clinical Neurophysiology and Neuroimaging Unit, Division of Neuropsychiatry, Department of Psychiatry, University Hospitals of Geneva, 2 Chemin du Petit Bel Air, 1225 Chene Bourg, Geneva, Switzerland
    Neuroscience 150:346-56. 2007
    ..They also show that P200 latency during the two-back task may be a simple and promising EEG marker of rapid cognitive decline in MCI...
  11. ncbi request reprint Cortical microinfarcts and demyelination affect cognition in cases at high risk for dementia
    E Kovari
    Department of Psychiatry, University of Geneva School of Medicine, Chene Bourg, Switzerland
    Neurology 68:927-31. 2007
    ..To investigate the possible synergistic effect of microvascular lesions with mild Alzheimer disease (AD) pathology in mixed cases...
  12. ncbi request reprint Clinical validity of A beta-protein deposition staging in brain aging and Alzheimer disease
    G Gold
    Department of Psychiatry, , University of Geneva School of Medicine, Switzerland
    J Neuropathol Exp Neurol 60:946-52. 2001
    ....
  13. pmc Neuropathological analysis of lacunes and microvascular lesions in late-onset depression
    M Santos
    Department of Psychiatry, University Hospitals and Faculty of Medicine of Geneva, Belle Idee, Geneva, Switzerland
    Neuropathol Appl Neurobiol 36:661-72. 2010
    ..More recently, we showed that thalamic and basal ganglia lacunes are associated with post-stroke depression and may affect emotional regulation. The present study examines whether this is also the case for late-onset depression...
  14. ncbi request reprint Decreased theta event-related synchronization during working memory activation is associated with progressive mild cognitive impairment
    Pascal Missonnier
    Neuroimaging Unit, University Hospitals of Geneva, Geneva, Switzerland
    Dement Geriatr Cogn Disord 22:250-9. 2006
    ..Previous studies suggested that synchronization likelihood analysis in theta-band frequency might be a sensitive method to identify early alterations of neuronal networks in mild cognitive impairment (MCI)...
  15. ncbi request reprint Diabetes, comorbidities and increased long-term mortality in older patients admitted for geriatric inpatient care
    D Zekry
    Department of Internal Medicine, Rehabilitation and Geriatrics, Geneva University Hospitals and University of Geneva, 3 chemin du Pont Bochet, Thonex, Switzerland
    Diabetes Metab 38:149-55. 2012
    ..To study the specific impact of diabetes on long-term mortality in very old subjects with multiple comorbidities and functional disabilities...
  16. doi request reprint Microvascular changes in late-life schizophrenia and mood disorders: stereological assessment of capillary diameters in anterior cingulate cortex
    L Sinka
    Department of Psychiatry, University Hospitals and School of Medicine of Geneva, Belle Idee, Geneva, Switzerland
    Neuropathol Appl Neurobiol 38:696-709. 2012
    ..Here, we analysed morphological parameters of capillaries in this area in elderly cases affected by these psychiatric disorders...
  17. ncbi request reprint Tangle and neuron numbers, but not amyloid load, predict cognitive status in Alzheimer's disease
    P Giannakopoulos
    Department of Psychiatry, HUG Belle Idée, University of Geneva School of Medicine, Switzerland
    Neurology 60:1495-500. 2003
    ..To examine the relationship between stereologic estimates of AD-related pathology and severity of cognitive deficits in brain aging...
  18. ncbi request reprint Telomere length, comorbidity, functional, nutritional and cognitive status as predictors of 5 years post hospital discharge survival in the oldest old
    D Zekry
    Department of Rehabilitation and Geriatrics, Geneva University Hospitals and University of Geneva, Thonex, Switzerland
    J Nutr Health Aging 16:225-30. 2012
    ..However the association between shorter telomeres with lower survival at advanced ages remains a controversial issue. This association could reflect the impact of other health conditions than a direct biological effect...
  19. ncbi request reprint Neuroanatomic correlates of visual agnosia in Alzheimer's disease: a clinicopathologic study
    P Giannakopoulos
    Department of Psychiatry, HUG Belle Idée, University of Geneva School of Medicine, Switzerland
    Neurology 52:71-7. 1999
    ..To examine the neuroanatomic correlates of visual agnosia in AD...
  20. ncbi request reprint Neural substrates of spatial and temporal disorientation in Alzheimer's disease
    P Giannakopoulos
    Department of Psychiatry, Clinic of Geriatric Psychiatry, HUG Belle Idée, Geneva, Switzerland
    Acta Neuropathol 100:189-95. 2000
    ..These observations are discussed with respect to the notion of global corticocortical disconnection in AD...
  21. ncbi request reprint Impaired processing of famous faces in Alzheimer's disease is related to neurofibrillary tangle densities in the prefrontal and anterior cingulate cortex
    P Giannakopoulos
    Department of Psychiatry, HUG Belle Idée, University of Geneva School of Medicine, Geneva, Switzerland
    Dement Geriatr Cogn Disord 11:336-41. 2000
    ..In agreement with previous studies, they also indicate that SP densities are not a good pathological correlate of neuropsychological deficits in AD...
  22. ncbi request reprint Re-evaluating the role of vascular changes in the differential diagnosis of Alzheimer's disease and vascular dementia
    G Gold
    Department of Geriatric, University of Geneva School of Medicine, Geneva, Switzerland
    Eur Neurol 40:121-9. 1998
    ..It may be time to reevaluate the dichotomy between AD and VaD...
  23. ncbi request reprint Morphological substrates of cognitive decline in nonagenarians and centenarians: a new paradigm?
    Anouk Imhof
    Department of Psychiatry, HUG, Belle Idee, University of Geneva School of Medicine, Geneva, Switzerland
    J Neurol Sci 257:72-9. 2007
    ....
  24. ncbi request reprint Validation of clinical criteria for possible vascular dementia in the oldest-old
    Jean Pierre Bacchetta
    Department of Psychiatry, University Hospitals of Geneva, Switzerland
    Neurobiol Aging 28:579-85. 2007
    ..Although their specificity was significantly lower in this age group compared to younger cohorts, all of them successfully exclude AD cases...
  25. ncbi request reprint Cognitive features in euthymic bipolar patients in old age
    Christophe Delaloye
    Division of Geriatric Psychiatry, University Hospitals of Geneva, Chene Bourg, Switzerland
    Bipolar Disord 11:735-43. 2009
    ..The second aim was to explore the interrelationship between these cognitive deficits and determine whether they reflect a single core impairment or the co-occurrence of independent cognitive deficits...
  26. ncbi request reprint Assessing the cognitive impact of Alzheimer disease pathology and vascular burden in the aging brain: the Geneva experience
    Panteleimon Giannakopoulos
    Division of Geriatric Psychiatry, Department of Psychiatry, University of Geneva School of Medicine, 1225 Chene Bourg, Geneva, Switzerland
    Acta Neuropathol 113:1-12. 2007
    ....
  27. ncbi request reprint Aging and working memory: early deficits in EEG activation of posterior cortical areas
    P Missonnier
    Neuroimaging Unit, University Hospitals of Geneva, Geneva, Switzerland
    J Neural Transm 111:1141-54. 2004
    ..The present results are consistent with the hypothesis of decreased brain reserve in the elderly and provide evidence for age-related deficits in the recruitment of posterior cortical neurons with increasing working memory load...
  28. ncbi request reprint Frontal theta event-related synchronization: comparison of directed attention and working memory load effects
    P Missonnier
    Neuroimaging Unit, University Hospitals of Geneva, 1225 Geneva, Switzerland
    J Neural Transm 113:1477-86. 2006
    ....
  29. doi request reprint Aging effects on selective attention-related electroencephalographic patterns during face encoding
    M P Deiber
    INSERM U877, Faculty of Medicine, Domaine de la Merci, 38700 La Tronche, France
    Neuroscience 171:173-86. 2010
    ....
  30. doi request reprint Electrophysiological markers of rapid cognitive decline in mild cognitive impairment
    Panteleimon Giannakopoulos
    Department of Psychiatry, University Hospitals of Geneva, Chene Bourg, Geneva, Switzerland
    Front Neurol Neurosci 24:39-46. 2009
    ....
  31. doi request reprint Pathological substrates of cognitive decline in Alzheimer's disease
    Panteleimon Giannakopoulos
    Department of Psychiatry, University of Geneva School of Medicine, Chene Bourg, Geneva, Switzerland
    Front Neurol Neurosci 24:20-9. 2009
    ..The present review discusses the complex structure/function relationships in brain aging and AD within the theoretical framework of the functional neuropathology of brain aging...
  32. doi request reprint Individual prediction of cognitive decline in mild cognitive impairment using support vector machine-based analysis of diffusion tensor imaging data
    Sven Haller
    Service Neuro Diagnostique et Neuro Interventionnel DISIM, University Hospitals of Geneva, Geneva, Switzerland
    J Alzheimers Dis 22:315-27. 2010
    ....
  33. doi request reprint Does dementia predict adverse hospitalization outcomes? A prospective study in aged inpatients
    Dina Zekry
    Rehabilitation and Geriatrics Department, Geneva University, Thonex, Switzerland
    Int J Geriatr Psychiatry 24:283-91. 2009
    ..Dementia is often considered a predictor of adverse hospitalization outcomes. However, the relative contributions of dementia and other risk factors remain unclear...
  34. doi request reprint Telomere length is not predictive of dementia or MCI conversion in the oldest old
    Dina Zekry
    Department of Rehabilitation and Geriatrics, Geneva University Hospitals and University of Geneva, Switzerland
    Neurobiol Aging 31:719-20. 2010
    ....
  35. doi request reprint Abnormal-induced theta activity supports early directed-attention network deficits in progressive MCI
    Marie Pierre Deiber
    Department of Psychiatry, University Hospitals of Geneva, Switzerland
    Neurobiol Aging 30:1444-52. 2009
    ..While performance is maintained, the decrease of induced theta activity suggests early deficits in the directed-attention network in progressive MCI, whereas this network is functionally preserved in stable MCI...
  36. ncbi request reprint Lewy body densities in the entorhinal and anterior cingulate cortex predict cognitive deficits in Parkinson's disease
    Eniko Kovari
    Department of Psychiatry, HUG Belle Idée, University of Geneva School of Medicine, Geneva, Switzerland
    Acta Neuropathol 106:83-8. 2003
    ..They also suggest that LB formation in limbic areas may be crucial for the development of PD dementia...
  37. ncbi request reprint Mixed dementia: epidemiology, diagnosis, and treatment
    Dina Zekry
    Hopitaux Universitaires de Geneve, Thonex, Switzerland
    J Am Geriatr Soc 50:1431-8. 2002
    ....
  38. ncbi request reprint Commentary: European initiatives and future fields of interest in geriatric medicine
    Reto W Kressig
    Geriatric Department, Medical School and University Hospitals of Geneva, Route de Mon Idee CH, 1226 Thônex Genève, Switzerland
    J Gerontol A Biol Sci Med Sci 59:1163-4; discussion 1132-52. 2004
  39. doi request reprint Volumetric MRI changes, cognition and personality traits in old age depression
    Kerstin Weber
    Division of Geriatric Psychiatry, University Hospitals of Geneva and Faculty of Medicine of the University of Geneva, 1225 Geneva, Switzerland
    J Affect Disord 124:275-82. 2010
    ..Integrative aetiological models assessing concomitantly these parameters as well as markers of psychological vulnerability such as persistent personality traits, are still lacking for this age group...
  40. doi request reprint Neuroanatomical and neuropsychological features of euthymic patients with bipolar disorder
    Christophe Delaloye
    Division of Geriatric Psychiatry, University Hospitals of Geneva and Faculty of Medicine, Switzerland
    Am J Geriatr Psychiatry 17:1012-21. 2009
    ..To explore this issue, the authors performed a case-control study including detailed neuropsychological and magnetic resonance imaging analyses in 17 euthymic elderly patients with BD and 17 healthy individuals...
  41. doi request reprint Early disturbances of gamma band dynamics in mild cognitive impairment
    Pascal Missonnier
    Clinical Neurophysiology and Neuroimaging Unit, Division of Neuropsychiatry, Department of Psychiatry, Geneva University Hospitals, University of Geneva, 2 Chemin du Petit Bel Air, Chene Bourg, 1225 Geneva, Switzerland
    J Neural Transm 117:489-98. 2010
    ..8% of the cognitive variability in this series. Our data indicate that the progression of cognitive decline in MCI is associated with early deficits in temporal binding that occur during the activation of selective attention processes...
  42. ncbi request reprint Geriatrics index of comorbidity was the most accurate predictor of death in geriatric hospital among six comorbidity scores
    Dina Zekry
    Rehabilitation and Geriatrics Department, Geneva University, chemin du Pont Bochet, Thonex, Switzerland
    J Clin Epidemiol 63:1036-44. 2010
    ....
  43. doi request reprint Potentially inappropriate prescribing including under-use amongst older patients with cognitive or psychiatric co-morbidities
    Pierre Olivier Lang
    Department of Rehabilitation and Geriatrics, Medical School and University Hospitals of Geneva, Geneva, Switzerland
    Age Ageing 39:373-81. 2010
    ..the study aimed to determine the prevalence of and risk factors for inappropriate prescribing (IP) and prescribing omission (PO) in elderly with mental co-morbidities...
  44. ncbi request reprint Psychometric properties of the Doloplus-2 observational pain assessment scale and comparison to self-assessment in hospitalized elderly
    Sophie Pautex
    Department of Rehabilitation and Geriatrics, Geneva University Hospitals, Switzerland
    Clin J Pain 23:774-9. 2007
    ..In this follow-up study, we report the psychometric properties of the observational Doloplus-2 scale using the visual analog scale (VAS) pain score as a gold standard and evaluate its performance...
  45. ncbi request reprint Cerebral microhemorrhage and iron deposition in mild cognitive impairment: susceptibility-weighted MR imaging assessment
    Sven Haller
    Department of Diagnostic and Interventional Neuroradiology, DISIM, University Hospitals of Geneva, Rue Gabrielle Perret Gentil 4, 1211 Geneva 14, Switzerland
    Radiology 257:764-73. 2010
    ..To test whether susceptibility-weighted magnetic resonance imaging at baseline may help predict cognitive decline...
  46. ncbi request reprint Feasibility and reliability of four pain self-assessment scales and correlation with an observational rating scale in hospitalized elderly demented patients
    Sophie Pautex
    Department of Geriatrics, Geneva University Hospitals, Switzerland
    J Gerontol A Biol Sci Med Sci 60:524-9. 2005
    ..The aim of this study was to evaluate the feasibility and reliability of four pain self-assessment scales in this population and compare their performance to an observational pain rating scale...
  47. ncbi request reprint Management of mixed dementia
    Dina Zekry
    Rehabilitation and Geriatrics Department, Geneva University, Thonex, Switzerland
    Drugs Aging 27:715-28. 2010
    ..Treatment of cardiovascular risk factors, especially hypertension, may protect brain function and should be included in prevention strategies for MD...
  48. doi request reprint Small vascular and Alzheimer disease-related pathologic determinants of dementia in the oldest-old
    Lidia Sinka
    Department of Psychiatry, University of Geneva School of Medicine, Geneva, Switzerland
    J Neuropathol Exp Neurol 69:1247-55. 2010
    ..Most importantly, single cutoff scores for these variables that could be used in the future to formulate neuropathologic criteria for mixed dementia in this age group were identified...
  49. ncbi request reprint Pain in severe dementia: self-assessment or observational scales?
    Sophie Pautex
    Department of Rehabilitation and Geriatrics, Geneva University Hospitals, Geneva, Switzerland
    J Am Geriatr Soc 54:1040-5. 2006
    ..To assess the performance of self-assessment scales in severely demented hospitalized patients and to compare it with observational data...
  50. ncbi request reprint Distinction between perceptual and attentional processing in working memory tasks: a study of phase-locked and induced oscillatory brain dynamics
    Marie Pierre Deiber
    University Hospitals of Geneva, Switzerland
    J Cogn Neurosci 19:158-72. 2007
    ..Induced theta and beta activities displayed respectively a frontal and parietal topographical distribution, providing further functional information on the fronto-posterior network supporting working memory...
  51. ncbi request reprint Mild cognitive impairment, degenerative and vascular dementia as predictors of intra-hospital, short- and long-term mortality in the oldest old
    Dina Zekry
    Rehabilitation and Geriatrics Department, University of Geneva, Thonex, Switzerland
    Aging Clin Exp Res 23:60-6. 2011
    ..We investigated intra-hospital, 1- and 5-year mortality risk associated with dementia and its various etiologies in a very old population after discharge from acute care...
  52. ncbi request reprint End-of-life care of persons with dementia
    Jean Pierre Michel
    Geriatric Department, Geneva University Hospitals, Switzerland
    J Gerontol A Biol Sci Med Sci 57:M640-4. 2002
    ..This goal includes the improvement of our communication skills with the patient, and the facilitation of interdisciplinary exchanges with the caregiver's team and with the family members to allow acceptance of the death...
  53. ncbi request reprint Demented versus non-demented very old inpatients: the same comorbidities but poorer functional and nutritional status
    Dina Zekry
    Geneva University, Rehabilitation and Geriatrics Department, 3, chemin du Pont Bochet, CH 1226, Thonex, Switzerland
    Age Ageing 37:83-9. 2008
    ..demented patients have been reported to be healthier than other old people of the same age...
  54. ncbi request reprint Cortical microinfarcts and demyelination significantly affect cognition in brain aging
    Eniko Kovari
    Department of Psychiatry, HUG Belle Idée, University of Geneva School of Medicine, Geneva, Switzerland
    Stroke 35:410-4. 2004
    ..To evaluate the cognitive consequences of such lesions, we prospectively investigated elderly individuals with various degrees of cognitive impairment but without significant neurofibrillary tangle pathology or macrovascular lesions...
  55. ncbi request reprint Structured assessment of mental health status in psychogeriatrics: validity of the French HoNOS65+
    Alessandra Canuto
    Division of Geriatric Psychiatry, University Hospitals of Geneva, Switzerland
    Can J Psychiatry 52:37-45. 2007
    ..To assess the reliability, validity, and feasibility of a French version of the Health of the Nation Outcome Scales for Elderly People (HoNOS65+)...
  56. ncbi request reprint A new electrophysiological index for working memory load in humans
    Pascal Missonnier
    Neuroimaging Unit, Clinic of Geriatric Psychiatry, Department of Psychiatry, University Hospitals of Geneva, Chemin du Petit Bel Air 2, CH 1225 Chene Bourg, Geneva, Switzerland
    Neuroreport 14:1451-5. 2003
    ..Our results imply that the PNwm represents a new electrophysiological index for working memory load in humans...
  57. ncbi request reprint Does the mini nutritional assessment predict hospitalization outcomes in older people?
    M C Van Nes
    Department of Geriatric Medicine, University Hospitals, Geneva, Switzerland
    Age Ageing 30:221-6. 2001
    ..the Mini Nutritional Assessment is a validated clinical tool for the assessment of nutritional status in older people. Moderate to severe malnutrition is common in elderly patients in hospital and is associated with a poor outcome...
  58. ncbi request reprint Economic considerations of Alzheimer's disease and related disorders
    J P Michel
    Department of Geriatrics, Geneva University Hospitals, Switzerland
    Aging (Milano) 13:255-60. 2001
    ..Thus, directing efforts at early diagnosis and delaying nursing home placement are two key cost-containment interventions. In this respect, the need to support informal care should not be underestimated...
  59. doi request reprint Longitudinal analysis of cognitive performances and structural brain changes in late-life bipolar disorder
    C Delaloye
    Division of Geriatric Psychiatry, University Hospitals of Geneva, Switzerland
    Int J Geriatr Psychiatry 26:1309-18. 2011
    ..To address this issue, we performed a 2-year longitudinal study including detailed neuropsychological and magnetic resonance imaging (MRI) analyses of 15 euthymic older BD patients and 15 controls...
  60. ncbi request reprint ADC mapping of the aging frontal lobes in mild cognitive impairment
    K O Lovblad
    Neuroradiology SRRI, Geneva University Hospital, HUG, Rue Micheli du Crest 24, 1211 Geneva, Switzerland
    Neuroradiology 46:282-6. 2004
    ..326, p=0.002). This increase was observed in both patients groups (LA+ and LA-). In addition, the LA+ group had significant higher ADC values than the LA- group after controlling for age (p<0.0001)...
  61. ncbi request reprint Specific BACE1 genotypes provide additional risk for late-onset Alzheimer disease in APOE epsilon 4 carriers
    Gabriel Gold
    Department of Geriatrics, Belle Idée Hospital Center, University Hospitals of Geneva, Geneva, Switzerland
    Am J Med Genet B Neuropsychiatr Genet 119:44-7. 2003
    ....
  62. ncbi request reprint Differential impact of lacunes and microvascular lesions on poststroke depression
    Micaela Santos
    Department of Psychiatry, University Hospitals and Faculty of Medicine of Geneva, Belle Idee, Geneva, Switzerland
    Stroke 40:3557-62. 2009
    ..We performed a detailed analysis of all types of microvascular lesions and lacunes in 41 prospectively documented and consecutively autopsied stroke cases...
  63. ncbi request reprint Cortical ubiquitin-positive inclusions in frontotemporal dementia without motor neuron disease: a quantitative immunocytochemical study
    Eniko Kovari
    Departments of Psychiatry and Geriatrics, HUG Belle Idée, University of Geneva School of Medicine, 1225, Geneva, Switzerland
    Acta Neuropathol 108:207-12. 2004
    ..They also reveal that the development of ubiquitin-positive inclusion densities in the dentate gyrus may be associated with a more aggressive form of the disease...
  64. ncbi request reprint Older patients in the emergency department: a review
    Nikolaos Samaras
    Department of Community Medicine and Primary Care, Geneva University Hospitals, Geneva, Switzerland
    Ann Emerg Med 56:261-9. 2010
    ..Complete geriatric assessments are time consuming and beyond the scope of most EDs. We propose a strategy based on the targeting of high-risk patients and provide examples of simple and efficient tools that are appropriate for ED use...
  65. ncbi request reprint [The economical impact of dementia]
    Sylvie Bonin-Guillaume
    Service de médecine interne gériatrie, Assistance Publique des Hopitaux de Marseille, CHU Nord
    Presse Med 34:35-41. 2005
    ..The current question is to know whether present and future medical treatments will be able to reduce the tremendous financial costs of this chronic disease...
  66. ncbi request reprint Cognitive impact of neuronal pathology in the entorhinal cortex and CA1 field in Alzheimer's disease
    Armin von Gunten
    Service of Old Age Psychiatry, University of Lausanne School of Medicine, 1008 Prilly, Lausanne, Switzerland
    Neurobiol Aging 27:270-7. 2006
    ..Moreover, they show that less than 50% of the cognitive variability may be attributable to AD neuronal pathology in these areas...
  67. ncbi request reprint Early event-related potential changes during working memory activation predict rapid decline in mild cognitive impairment
    Pascal Missonnier
    Neuroimaging Unit, Department of Psychiatry, University of Hospitals Geneva, Ch Pont Bochet 3, 1226 Thonex Geneva, Switzerland
    J Gerontol A Biol Sci Med Sci 60:660-6. 2005
    ..Using a "2-back" activation paradigm, we recently described an electrophysiological correlate of working memory activation (positive-negative working memory [PN(wm)] component) over parietal electrodes...
  68. ncbi request reprint Stereologic evidence for persistence of viable neurons in layer II of the entorhinal cortex and the CA1 field in Alzheimer disease
    Patrick R Hof
    Kastor Neurobiology of Aging Laboratories and Fishberg Research Center for Neurobiology, and Department of Geriatrics and Adult Development, Mount Sinai School of Medicine, New York, New York 10029, USA
    J Neuropathol Exp Neurol 62:55-67. 2003
    ....
  69. ncbi request reprint Metabolic correlates of behavioral and affective disturbances in frontal lobe pathologies
    Marie Sarazin
    Inserm E 007 and Federation of Neurology, Salpetriere Hospital, Paris, France
    J Neurol 250:827-33. 2003
    ..The aim of this study was to investigate the metabolic correlates of these deficits in a group of non-selected consecutive patients with frontal lobe lesions...
  70. ncbi request reprint Pathological correlates of poststroke depression in elderly patients
    Vasilis P Bozikas
    Department of Psychiatry, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece
    Am J Geriatr Psychiatry 13:166-9. 2005
    ..The authors examined the relationship between poststroke depression and location of stroke...
  71. ncbi request reprint [Treatment of Alzheimer's disease: clinicians's lecture]
    Sabine Joray
    Rev Med Suisse 2:307. 2006
  72. doi request reprint Comparative value of medical diagnosis versus physical functioning in predicting the 6-year survival of 1951 hospitalized old patients
    Emilia Frangos Lordos
    Department of Rehabilitation and Geriatrics, Geneva Medical School and University Hospitals, 3 chemin du Pont Bochet, Thonex Geneve, Switzerland
    Rejuvenation Res 11:829-36. 2008
  73. ncbi request reprint Symptom relief in the last week of life: is dementia always a limiting factor?
    Sophie Pautex
    J Am Geriatr Soc 55:1316-7. 2007