- Detecting long-range chromatin interactions using the chromosome conformation capture sequencing (4C-seq) methodNele Gheldof
Center for Integrative Genomics, University of Lausanne, Le Génopode, Quartier UNIL Sorge, Lausanne, Switzerland
Methods Mol Biol 786:211-25. 2012..The method is presented for use in mammalian cell lines, but can be adapted to use in mammalian tissues and any other eukaryotic genome...
- Structural variation-associated expression changes are paralleled by chromatin architecture modificationsNele Gheldof
Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland
PLoS ONE 8:e79973. 2013..We conclude that large genomic rearrangements can lead to chromatin conformation changes that extend far away from the structural variant, thereby possibly modulating expression globally and modifying the phenotype...