P Gervaz

Summary

Affiliation: University Hospital
Country: Switzerland

Publications

  1. doi A prospective, randomized, single-blind comparison of laparoscopic versus open sigmoid colectomy for diverticulitis
    Pascal Gervaz
    Departments of Surgery, Geneva University Hospital and Medical School, Geneva, Switzerland
    Ann Surg 252:3-8. 2010
  2. doi A clinical and radiological comparison of sigmoid diverticulitis episodes 1 and 2
    P Gervaz
    Department of Surgery Radiology, Geneva University Hospital and Medical School, Geneve, Switzerland
    Colorectal Dis 14:463-8. 2012
  3. pmc Results of emergency Hartmann's operation for obstructive or perforated left-sided colorectal cancer
    Pierre Charbonnet
    Department of Surgery, University Hospital Geneva, Switzerland
    World J Surg Oncol 6:90. 2008
  4. pmc Perforated Meckel's diverticulitis complicating active Crohn's ileitis: a case report
    Frank Schwenter
    Department of Surgery, University Hospital and Medical School Geneva, 1211 Geneva 14, Switzerland
    J Med Case Reports 3:12. 2009
  5. pmc Predicting survival after pulmonary metastasectomy for colorectal cancer: previous liver metastases matter
    Ulrich Landes
    Department of Surgery, Geneva University Hospital and Medical School, Geneva, Switzerland
    BMC Surg 10:17. 2010
  6. pmc Phlegmonous colitis: another source of sepsis in cirrhotic patients?
    Thomas Holzer
    Department of Surgery, Geneva University Hospital and Medical School, 1211 Geneva, Switzerland
    BMC Gastroenterol 9:94. 2009
  7. ncbi Chemotherapeutic options in the management of anal cancer
    Pascal Gervaz
    Hopital Cantonal Universitaire de Geneve, Clinique de Chirurgie Viscérale, Switzerland
    Expert Opin Pharmacother 5:2479-84. 2004
  8. ncbi Diagnosis and management of anal cancer
    Pascal Gervaz
    Clinique de Chirurgie Viscérale, Hopital Cantonal Universitaire de Geneve, Geneve, Switzerland
    Curr Gastroenterol Rep 10:502-6. 2008
  9. ncbi Proximal location of colon cancer is a risk factor for development of metachronous colorectal cancer: a population-based study
    Pascal Gervaz
    Department of Visceral Surgery, University Hospital Geneva, 24 Rue Micheli du Crest, 1211 Geneva, Switzerland
    Dis Colon Rectum 48:227-32. 2005
  10. ncbi A Prospective longitudinal evaluation of quality of life after abdominoperineal resection
    Pascal Gervaz
    Department of Surgery, University Hospital Geneva, Geneva, Switzerland
    J Surg Oncol 97:14-9. 2008

Collaborators

Detail Information

Publications74

  1. doi A prospective, randomized, single-blind comparison of laparoscopic versus open sigmoid colectomy for diverticulitis
    Pascal Gervaz
    Departments of Surgery, Geneva University Hospital and Medical School, Geneva, Switzerland
    Ann Surg 252:3-8. 2010
    ..The aim of this study was to compare open and laparoscopic sigmoid resection for diverticulitis with the patient and the nursing staff blinded to the surgical approach...
  2. doi A clinical and radiological comparison of sigmoid diverticulitis episodes 1 and 2
    P Gervaz
    Department of Surgery Radiology, Geneva University Hospital and Medical School, Geneve, Switzerland
    Colorectal Dis 14:463-8. 2012
    ..We compared the clinical and radiological severity, the respective location and clinical outcome of the first two episodes of sigmoid diverticulitis...
  3. pmc Results of emergency Hartmann's operation for obstructive or perforated left-sided colorectal cancer
    Pierre Charbonnet
    Department of Surgery, University Hospital Geneva, Switzerland
    World J Surg Oncol 6:90. 2008
    ..The aim of this study was to assess the surgical (operative mortality), and oncological (long-term survival after curative resection) results of emergency HP for obstructive or perforated left-sided CRC...
  4. pmc Perforated Meckel's diverticulitis complicating active Crohn's ileitis: a case report
    Frank Schwenter
    Department of Surgery, University Hospital and Medical School Geneva, 1211 Geneva 14, Switzerland
    J Med Case Reports 3:12. 2009
    ..We describe an original surgical approach in a young woman presenting with a combination of perforated Meckel's diverticulitis and active Crohn's ileitis...
  5. pmc Predicting survival after pulmonary metastasectomy for colorectal cancer: previous liver metastases matter
    Ulrich Landes
    Department of Surgery, Geneva University Hospital and Medical School, Geneva, Switzerland
    BMC Surg 10:17. 2010
    ..The aim of this study was to determine the impact of various parameters on survival after pulmonary metastasectomy for CRC...
  6. pmc Phlegmonous colitis: another source of sepsis in cirrhotic patients?
    Thomas Holzer
    Department of Surgery, Geneva University Hospital and Medical School, 1211 Geneva, Switzerland
    BMC Gastroenterol 9:94. 2009
    ..The clinical relevance of phlegmonous colitis (PC), a rare autopsy finding in cirrhotic patients, is poorly documented. We postulated that PC might be a source of sepsis in patients with portal hypertensive colopathy (PHC)...
  7. ncbi Chemotherapeutic options in the management of anal cancer
    Pascal Gervaz
    Hopital Cantonal Universitaire de Geneve, Clinique de Chirurgie Viscérale, Switzerland
    Expert Opin Pharmacother 5:2479-84. 2004
    ..Finally, the authors' opinion regarding currently unresolved issues in the treatment of these rare neoplasms is expressed...
  8. ncbi Diagnosis and management of anal cancer
    Pascal Gervaz
    Clinique de Chirurgie Viscérale, Hopital Cantonal Universitaire de Geneve, Geneve, Switzerland
    Curr Gastroenterol Rep 10:502-6. 2008
    ....
  9. ncbi Proximal location of colon cancer is a risk factor for development of metachronous colorectal cancer: a population-based study
    Pascal Gervaz
    Department of Visceral Surgery, University Hospital Geneva, 24 Rue Micheli du Crest, 1211 Geneva, Switzerland
    Dis Colon Rectum 48:227-32. 2005
    ..This study was undertaken to assess the incidence of 1) metachronous colorectal cancer and 2) subsequent extracolonic cancers, in relation to the location (proximal or distal to the splenic flexure) of the first primary colorectal tumor...
  10. ncbi A Prospective longitudinal evaluation of quality of life after abdominoperineal resection
    Pascal Gervaz
    Department of Surgery, University Hospital Geneva, Geneva, Switzerland
    J Surg Oncol 97:14-9. 2008
    ..Abdominoperineal resection (APR) is a disfiguring procedure, frequently associated with significant urogenital dysfunction. The aim of this prospective study was to repeatedly assess quality of life (QoL) 1, 6, and 12 months after APR...
  11. ncbi Molecular biology of squamous cell carcinoma of the anus
    P Gervaz
    Department of Surgery, University Hospital Geneva, Geneva, Switzerland
    Br J Surg 93:531-8. 2006
    ..This paper reviews the existing literature relating to the molecular biology of anal squamous cell carcinoma and proposes a theory of pathogenesis...
  12. ncbi The duration of postoperative ileus after elective colectomy is correlated to surgical specialization
    Pascal Gervaz
    Department of Surgery, University Hospital of Geneva, Geneva, Switzerland
    Int J Colorectal Dis 21:542-6. 2006
    ..The aim of this study was to measure the role of various clinical determinants on restoration of intestinal function after elective colorectal surgery...
  13. ncbi Two colons-two cancers: paradigm shift and clinical implications
    Pascal Gervaz
    Department of Surgery, University Hospital Geneva, Geneva, Switzerland
    J Surg Oncol 88:261-6. 2004
    ..In the future, clinical decision-making regarding adjuvant chemotherapy might be stratified according to the MSI status of cancers located proximally to the splenic flexure...
  14. doi Surgical management of gastrointestinal stromal tumours
    P Gervaz
    Department of Surgery, University Hospital Geneva, Geneva, Switzerland
    Br J Surg 96:567-78. 2009
    ..Operative and medical management of GISTs is rapidly evolving, but current guidelines appear restricted to basic non-organ-specific recommendations...
  15. ncbi [Management of sigmoid diverticulitis]
    P Gervaz
    Clinique de Chirurgie Viscérale, Departement de Chirurgie, HUG, 1211 Geneve
    Rev Med Suisse 5:1416-20. 2009
    ..Both stages require an emergent laparotomy. Indications for an elective sigmoidectomy are: a) two or more previous episodes of simple diverticulitis; and b) one episode of complicated diverticulitis...
  16. pmc Squamous cell carcinoma of the anus-an opportunistic cancer in HIV-positive male homosexuals
    Pascal Gervaz
    Department of Surgery, Geneva University Hospital and Medical School, 1211 Geneve, Switzerland
    World J Gastroenterol 17:2987-91. 2011
    ..In addition, definitive eradication of oncogenic HPVs within the anogenital mucosa of high-risk individuals might require a proactive approach with repeated vaccination...
  17. doi Laparoscopic versus open sigmoid resection for diverticulitis: long-term results of a prospective, randomized trial
    Pascal Gervaz
    Department of Surgery, Geneva University Hospital and Medical School, Geneva, Switzerland
    Surg Endosc 25:3373-8. 2011
    ..Elective laparoscopic sigmoid resection for diverticulitis has proven short-term benefits, but little data are available from prospective randomized trials regarding long-term outcome, quality of life, and functional results...
  18. doi Trans-sacral (Kraske) approach for gastrointestinal stromal tumour of the lower rectum: old procedure for a new disease
    P Gervaz
    Department of Surgery, University Hospital Geneva, Geneva, Switzerland
    Colorectal Dis 10:951-2. 2008
    ..Lower rectum GISTs are good indications for the Kraske procedure, and this relatively new disease entity may contribute to the reintroduction of an old procedure into the armamentarium of 21(st) century colorectal surgeons...
  19. ncbi A tale of two colons and two cancers. Distinct carcinogenesis and clinical outcome according to location proximal or distal to the splenic flexure
    P Gervaz
    Clinique de Chirurgie Digestive, Hopital Cantonal Universitaire de Geneve
    Swiss Surg 9:3-7. 2003
    ....
  20. ncbi Squamous cell carcinoma of the anus: another sexually transmitted disease
    Pascal Gervaz
    Clinique de Chirurgie Viscérale, Hopital Cantonal Universitaire de Geneve
    Swiss Med Wkly 133:353-9. 2003
    ..In the future, cytological screening of male homosexuals with an anal Papanicolaou test may help in identifying high-grade dysplasia and preventing anal cancer...
  21. ncbi Long-term expression of fibrogenic cytokines in radiation-induced damage to the internal anal sphincter
    P Gervaz
    Department of Visceral Surgery and Transplantation, University Hospital Geneva, Switzerland
    Swiss Surg 9:193-7. 2003
    ..There is accumulating evidence, both quantitative and qualitative, that pelvic irradiation affects anorectal function. However, the molecular mechanisms responsible for radiation-induced damage to the anal sphincter remain unclear...
  22. ncbi Molecular aspects of intestinal radiation-induced fibrosis
    Pascal Gervaz
    Clinique de Chirurgie Digestive, Hopital Universitaire de Geneve, 24 Rue Micheli du Crest, 1211 Geneve 14, Switzerland
    Curr Mol Med 9:273-80. 2009
    ....
  23. ncbi Treatment strategies for the management of advanced colorectal liver metastases detected synchronously with the primary tumour
    G Mentha
    Department of Surgery, University Hospital of Geneva, Geneva, Switzerland
    Eur J Surg Oncol 33:S76-83. 2007
    ....
  24. ncbi Percutaneous CT scan-guided drainage vs. antibiotherapy alone for Hinchey II diverticulitis: a case-control study
    D Brandt
    Department of Surgery, University Hospital Geneva, Rue Micheli du Crest 24, 1211 Geneva, Switzerland
    Dis Colon Rectum 49:1533-8. 2006
    ..This study was undertaken to compare the results of percutaneous drainage vs. antibiotic therapy alone in patients with Hinchey II diverticulitis...
  25. ncbi [Really so far from fast-track colorectal surgery in senior patients?]
    S Ostermann
    Service de Chirurgie Viscerale, Departement de Chirurgie, HUG, 1211 Geneve 14
    Rev Med Suisse 5:1676-9. 2009
    ..Elective colorectal surgery should be offered to senior patients. However the relative high morbidity rate with standard care prompts us to initiate a specifically designed fast-track protocol in senior patients...
  26. ncbi An audit of surgical management of gastrointestinal stromal tumours (GIST)
    P Bucher
    Department of Surgery, Visceral and Transplantation Surgery Clinic, Geneva University Hospital, 24 Rue Micheli du Crest, 1211 Geneva 14, Switzerland
    Eur J Surg Oncol 32:310-4. 2006
    ..To analyze GIST outcome after primary resection and to determine if a new grading system could adequately predict there prognosis...
  27. ncbi Results from percutaneous drainage of Hinchey stage II diverticulitis guided by computed tomography scan
    Y Durmishi
    Department of Surgery, University Hospital Geneva, Rue Micheli du Crest 24, 1211, Geneve, Switzerland
    Surg Endosc 20:1129-33. 2006
    ..The rationale behind this approach is to manage the septic complication conservatively and to follow this later using elective sigmoidectomy with primary anastomosis...
  28. doi Scoring system to predict the risk of surgical-site infection after colorectal resection
    P Gervaz
    Department of Surgery, Geneva University Hospital and Medical School, Geneva, Switzerland
    Br J Surg 99:589-95. 2012
    ..Generic scores, such as the National Nosocomial Infections Surveillance index, are not used by colorectal surgeons...
  29. ncbi Randomized clinical trial of mechanical bowel preparation versus no preparation before elective left-sided colorectal surgery
    P Bucher
    Clinic of Visceral and Transplantation Surgery, Department of Surgery, Geneva University Hospital, Geneva 14, Switzerland
    Br J Surg 92:409-14. 2005
    ..The aim of this randomized clinical trial was to compare the outcome of patients who underwent elective left-sided colorectal surgery with or without MBP...
  30. ncbi [Vacuum-assisted abdominal closure: its role in the treatment of complex abdominal and perineal wounds. Experience in 48 patients]
    Y Durmishi
    Departement de Chirurgie, Hopital Universitaire de Geneve, 24 Rue Micheli du Crest, Geneva, Switzerland
    J Chir (Paris) 144:209-13. 2007
    ..Vacuum-assisted closure (VAC) is a promising approach for the management of complex abdominal and perineal wounds. This paper summarizes our experience with this therapeutic modality and demonstrates its efficacity in difficult situations...
  31. doi Clinicoradiological score for predicting the risk of strangulated small bowel obstruction
    F Schwenter
    Department of Surgery, Geneva University Hospital and Medical School, Geneva, Switzerland
    Br J Surg 97:1119-25. 2010
    ..Intestinal ischaemia as a result of small bowel obstruction (SBO) requires prompt recognition and early intervention. A clinicoradiological score was sought to predict the risk of ischaemia in patients with SBO...
  32. ncbi [Acute small bowel obstruction: conservative or surgical treatment?]
    F Schwenter
    Service de chirurgie viscérale et de transplantation, Departement de Chirurgie, HUG, Geneve 14
    Rev Med Suisse 7:1341-4, 1346-7. 2011
    ..Here we review the principles of adhesive SBO management and suggest a decision procedure for conservative versus surgical treatment...
  33. ncbi Laparoscopic versus open resection for appendix carcinoid
    P Bucher
    Clinic of Visceral and Transplantation Surgery, Department of Surgery, University Hospital Geneva, 24, Rue Micheli du Crest, 1211, Geneva, 14, Switzerland
    Surg Endosc 20:967-70. 2006
    ..The goal of this study was to compare results of laparoscopic (LAP) versus open (OP) appendectomy for AC according to intend to treat approach...
  34. ncbi Dukes B colorectal cancer: distinct genetic categories and clinical outcome based on proximal or distal tumor location
    P Gervaz
    Department of Surgery, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
    Dis Colon Rectum 44:364-72; discussion 372-3. 2001
    ..Location of the neoplasm in reference to the splenic flexure should be considered before group stratification in future trials of adjuvant chemotherapy in patients with Dukes B tumors...
  35. ncbi Long-term quality of life after endoscopic dilation of strictured colorectal or colocolonic anastomoses
    T Nguyen-Tang
    Service of Gastroenterology and Hepatology, Geneva University Hospitals, Micheli du Crest, 24, 1205, Geneva, Switzerland
    Surg Endosc 22:1660-6. 2008
    ..Endoscopic balloon dilation is the first-line treatment for benign colorectal anastomotic strictures. We aimed to objectively assess its long-term results...
  36. doi Assessment of recurrence and complications following uncomplicated diverticulitis
    N C Buchs
    Department of Surgery, Geneva University Hospital and Medical School, Geneva, Switzerland
    Br J Surg 100:976-9; discussion 979. 2013
    ..The natural history of sigmoid diverticulitis has been inferred from population-based or retrospective studies. This study assessed the risk of a recurrent attack following the first episode of uncomplicated diverticulitis...
  37. doi Sigmoid diverticulitis in 2011: many questions; few answers
    P Ambrosetti
    Clinique Générale Beaulieu, Geneva, Switzerland
    Colorectal Dis 14:e439-46. 2012
    ..Patients were studied after a first episode of acute left-colonic diverticulitis for the initial and later evolution of the disease with the aim of defining evidence-based indications for elective surgery...
  38. doi Risk factors for mortality-morbidity after emergency-urgent colorectal surgery
    K Skala
    Department of Surgery, University Hospital Geneva, Geneva, Switzerland
    Int J Colorectal Dis 24:311-6. 2009
    ..The aim of this study was to assess the risk factors associated with mortality and morbidity following emergency or urgent colorectal surgery...
  39. ncbi Paraganglioma of the ampulla of Vater: a potentially malignant neoplasm
    P Bucher
    Clinic of Visceral and Transplantation Surgery, Dept of Surgery, University Hospital of Geneva, Geneva, Switzerland
    Scand J Gastroenterol 39:291-5. 2004
    ..We propose that paragangliomas of the ampulla of Vater should be operated by cephalic pancreaticoduodenectomy, which allows long-term and disease-free survival...
  40. ncbi Oxaliplatin combined with irinotecan and 5-fluorouracil/leucovorin (OCFL) in metastatic colorectal cancer: a phase I-II study
    Y Seium
    Oncosurgery, Services of Visceral Surgery and Radiooncology, Geneva University Hospital, Geneva, Switzerland
    Ann Oncol 16:762-6. 2005
    ....
  41. doi Prevention, chemoradiation and surgery for anal cancer
    Nicolas C Buchs
    Department of Surgery, Geneva University Hospital and Medical School, Rue Micheli du Crest 24, 1211 Geneva, Switzerland
    Expert Rev Anticancer Ther 9:483-9. 2009
    ..This article reviews current evidence suggesting that a new, more preventive approach is needed in order to improve the clinical outcome of SCCA in HIV-positive patients...
  42. doi 'Liver first' approach in the treatment of colorectal cancer with synchronous liver metastases
    Gilles Mentha
    Department of Surgery, University Hospitals of Geneva, Geneva, Switzerland
    Dig Surg 25:430-5. 2008
    ..The present series updates on a previously reported pilot experience...
  43. ncbi Mechanical bowel preparation for elective colorectal surgery: a meta-analysis
    Pascal Bucher
    Clinic of Visceral and Transplantation Surgery, Department of Surgery and Division of Medical Statistics, Geneva University Hospital, Geneva, Switzerland
    Arch Surg 139:1359-64; discussion 1365. 2004
    ..There is little scientific evidence to support the routine practice of mechanical bowel preparation (MBP) before elective colorectal surgery in order to minimize the risk of postoperative septic complications...
  44. doi Water-immersion sigmoidoscopy to treat acute GI bleeding in the perioperative period after surgical colorectal anastomosis
    Jean Louis Frossard
    Service of Gastroenterology, Geneva University Hospital, Geneva, Switzerland
    Gastrointest Endosc 71:167-70. 2010
    ..The early treatment includes surgery or endoscopy, the latter being subject to complications associated with air insufflation and associated perforation...
  45. pmc Segmental duodenectomy for gastrointestinal stromal tumor of the duodenum
    Nicolas Christian Buchs
    Department of Surgery, University Hospital Geneva, 24 Rue Micheli du Crest, 1211, Geneva, Switzerland
    World J Gastroenterol 16:2788-92. 2010
    ..To evaluate the results of segmental duodenectomy (SD) and pancreaticoduodenectomy (PD) for duodenal gastrointestinal stromal tumor (GIST) and help clinicians with surgical management...
  46. ncbi Differential expression of anti-apoptotic protein Bcl-2 in keratinizing versus non-keratinizing squamous cell carcinoma of the anus
    Abdelkarim S Allal
    Division of Radiation Oncology, University Hospital Geneva, Rue Micheli du Crest 24, 1211 Geneva, Switzerland
    Int J Colorectal Dis 20:161-4. 2005
    ..The present study was undertaken to compare the expression of apoptosis-regulating proteins Bcl-2 and p53 in K versus NK SCCA...
  47. doi Risk factors for methicillin-resistant Staphylococcus aureus surgical site infection
    Stephan Harbarth
    Infection Control Program, University of Geneva Hospitals and Medical School, Geneva, Switzerland
    Infect Control Hosp Epidemiol 29:890-3. 2008
    ..MRSA carriage on admission did not predict MRSA SSI...
  48. doi Universal screening for methicillin-resistant Staphylococcus aureus at hospital admission and nosocomial infection in surgical patients
    Stephan Harbarth
    Infection Control Program, University of Geneva Hospitals and Medical School, Geneva, Switzerland
    JAMA 299:1149-57. 2008
    ..Experts and policy makers have repeatedly called for universal screening at hospital admission to reduce nosocomial methicillin-resistant Staphylococcus aureus (MRSA) infection...
  49. ncbi Preoperative concomitant hyperfractionated radiotherapy and gemcitabine for locally advanced rectal cancers: a phase I-II trial
    Abdelkarim S Allal
    Radiation Oncology Service, University Hospital of Geneva, 24 Rue Micheli du Crest, 1211 Geneva 14, Switzerland
    Cancer J 11:133-9. 2005
    ....
  50. ncbi Outcome of surgery for rectal cancer in octogenarians
    Elisabeth Andereggen
    Department of Surgery, University Hospital Geneva, Switzerland
    Swiss Med Wkly 136:185-8. 2006
    ..The aim of this study was to assess the outcome of surgery for rectal cancer in patients 80 years of age or more...
  51. ncbi Lessons learned from one thousand consecutive colonic resections in a teaching hospital
    Nicolas C Buchs
    Department of Surgery, University Hospital Geneva, 24 Rue Micheli du Crest, CH 1211 Geneva, Switzerland
    Swiss Med Wkly 137:259-64. 2007
    ..Elective colectomies are standard procedures carrying below 1% mortality; by contrast, emergency colonic resections remain surgical challenges in compromised and/or elderly patients and are associated with high complication rates...
  52. ncbi Long-term results of radical resection for locally advanced duodenal adenocarcinoma
    Pascal Bucher
    Clinic of Visceral and Transplantation Surgery, Department of Surgery University Hospital Geneva, Switzerland
    Hepatogastroenterology 52:1727-9. 2005
    ..Duodenal adenocarcinomas are uncommon tumors characterized by non-specific symptoms and late diagnosis. The objective of this study was to assess long-term results of locally advanced duodenal adenocarcinoma treated by surgical resection...
  53. ncbi Surgical treatment of appendiceal adenocarcinoid (goblet cell carcinoid)
    Pascal Bucher
    Clinic of Visceral and Transplantation Surgery, Department of Surgery, University Hospital Geneva, 24 Rue Micheli du Crest, Geneva 14, 1211 Switzerland
    World J Surg 29:1436-9. 2005
    ..The risk for developing colorectal adenocarcinoma seems to be extremely high in patients treated for appendiceal adenocarcinoid and warrants close follow-up with colonoscopic screening...
  54. ncbi Morphologic alterations associated with mechanical bowel preparation before elective colorectal surgery: a randomized trial
    Pascal Bucher
    Department of Surgery, Clinic of Visceral and Transplantation Surgery, Geneva, Switzerland
    Dis Colon Rectum 49:109-12. 2006
    ..This study was designed to determine whether mechanical bowel preparation is associated with histologic alterations in the colon...
  55. ncbi Totally intracorporeal laparoscopic colorectal anastomosis using circular stapler
    Pascal Bucher
    Visceral Surgery, Department of Surgery, Geneva University Hospital, 24, Rue Micheli du Crest, 1211, Geneva 14, Switzerland
    Surg Endosc 22:1278-82. 2008
    ..We report a new laparoscopic technique for totally intracorporeal colorectal circular anastomosis (TLCCA) using a circular stapler...
  56. ncbi Assessment of quality of life in patients with rectal cancer treated by preoperative radiotherapy: a longitudinal prospective study
    Abdelkarim S Allal
    Radiation Oncology Service, University Hospital of Geneva, 24 Micheli du Crest St, 1211 Geneva 14, Switzerland
    Int J Radiat Oncol Biol Phys 61:1129-35. 2005
    ..To assess prospectively the quality of life (QOL) of patients treated by preoperative radiotherapy (RT) and surgery for locally advanced rectal cancer...
  57. ncbi Incidence, consequences, and risk factors for anastomotic dehiscence after colorectal surgery: a prospective monocentric study
    Nicolas C Buchs
    Department of Surgery, University Hospital Geneva, Geneva, Switzerland
    Int J Colorectal Dis 23:265-70. 2008
    ..This study was designed to assess the incidence, to observe the consequences, and to identify the risk factors associated with anastomotic leakage after colorectal surgery...
  58. ncbi Multimedia article. Laparoscopic repair of parastomal hernia using a porcine dermal collagen (Permacol) implant
    Ihsan Inan
    Department of Surgery, University Hospital Geneva, Geneva, Switzerland
    Dis Colon Rectum 50:1465. 2007
    ..Permacol (Tissue Science Laboratories plc, Aldershot, Hampshire, U.K.) is a new biomaterial implant, which combines the strength and biocompatibility...
  59. ncbi Bleeding Meckel's diverticulum diagnosis: an unusual indication for computed tomography
    D Danzer
    Clinic of Digestive Surgery, Hopital Cantonal Universitaire de Geneve, 24 Rue Micheli du Crest, 1211 Geneva, Switzerland
    Abdom Imaging 28:631-3. 2003
    ..We present the case of a young patient with massive gastrointestinal hemorrhage, in whom the diagnosis of MD bleeding was preoperatively made with contrast-enhanced CT after two negatives arteriographies...
  60. pmc Cyclin D1, cyclin E, and p21 have no apparent prognostic value in anal carcinomas treated by radiotherapy with or without chemotherapy
    A S Allal
    Division of Radiation Oncology, University Hospital of Geneva, 24 Rue Micheli du Crest, 1211 Geneva 14, Switzerland
    Br J Cancer 91:1239-44. 2004
    ..07) in the N0 patients. The results of this study suggest that the cell-cycle proteins investigated are unlikely to be clinically useful in predicting treatment response or prognosis in patients with anal carcinomas...
  61. ncbi [Surgical treatment of duodenal stenosis in Crohn's disease]
    M Gonzalez
    Service de Chirurgie Viscerale, Hopital Universitaire de Geneve, 24, Rue Micheli du Crest, 1211 Geneve, Suisse
    Ann Chir 131:636-8. 2006
    ..When there is an indication for surgery, a gastroenterostomy is preferred, albeit with a high incidence of outlet obstruction and marginal ulceration...
  62. ncbi Comparison of microsatellite instability and chromosomal instability in predicting survival of patients with T3N0 colorectal cancer
    Pascal Gervaz
    Department of Surgery, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
    Surgery 131:190-7. 2002
    ..Their respective roles in predicting clinical outcomes of patients with T3N0 colorectal cancer remain unknown...
  63. pmc Human colon cancer epithelial cells harbour active HEDGEHOG-GLI signalling that is essential for tumour growth, recurrence, metastasis and stem cell survival and expansion
    Frédéric Varnat
    Department Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland
    EMBO Mol Med 1:338-51. 2009
    ..Targeting HH-GLI1, directly or indirectly, is thus predicted to decrease tumour bulk and eradicate CC stem cells and metastases...
  64. doi Functional outcome and quality of life after restorative proctocolectomy and ileo-anal pouch anastomosis
    Philippe Wuthrich
    Service de Chirurgie Viscerale, Hopital Universitaire de Geneve, Switzerland
    Swiss Med Wkly 139:193-7. 2009
    ..The aim of our study was to evaluate the functional results of this procedure and to assess its impact upon patient quality of life (QoL)...
  65. ncbi Colorectal adenocarcinoma in cirrhotic patients
    Pascal Gervaz
    Division of Colon and Rectal Surgery, Mayo Clinic, Rochester, MN 55905, USA
    J Am Coll Surg 196:874-9. 2003
    ..The aims of this study were to evaluate the incidence of liver metastasis, postoperative mortality, and the predictors of longterm survival...
  66. ncbi Influence of target gene mutations on survival, stage and histology in sporadic microsatellite unstable colon cancers
    Barbara Jung
    Department of Medicine, University of California, San Diego, and VA San Diego Healthcare System, CA 92161, USA
    Int J Cancer 118:2509-13. 2006
    ..Mutations in TGFBR2 and BAX may improve survival in MSI-H Dukes B2 patients, and mutations of ACVR2 may augment histological changes consistent with poor tumor grade that is characteristic of MSI-H colon cancers, and increase tumor size...
  67. ncbi Histologic analysis of the irradiated anal sphincter
    Giovanna M da Silva
    Department of Colorectal Surgery, Cleveland Clinic Florida, Weston and Naples, Florida 33331, USA
    Dis Colon Rectum 46:1492-7. 2003
    ....
  68. pmc Should preoperative mechanical bowel preparation be abandoned?
    Pascal Bucher
    Ann Surg 245:662. 2007
  69. ncbi Improved long-term outcome of surgery for advanced colorectal liver metastases: reasons and implications for management on the basis of a severity score
    Axel Andres
    Unit of Visceral and Transplantation Surgery, University Hospitals of Geneva, 1211, Geneva 14, Switzerland
    Ann Surg Oncol 15:134-43. 2008
    ..To quantify this assumption and to understand its causes we analyzed a series of patients on the basis of a standardized severity score and changes in management occurring over the years...
  70. ncbi Molecular biology of squamous cell carcinoma of the anus: a comparison of HIV-positive and HIV-negative patients
    Pascal Gervaz
    Department of Colon and Rectal Surgery, Mayo Clinic, Rochester, MN 55905, USA
    J Gastrointest Surg 8:1024-30; discussion 1031. 2004
    ..These data suggest that immunosuppression may promote SCCA progression through an alternate pathway and that persistence of HPV infection within the anal canal may play a central role in this process...
  71. ncbi T0 N1 adenocarcinoma of the colon following oxaliplatin-based neoadjuvant chemotherapy
    Pascal Gervaz
    J Surg Oncol 97:94-5. 2008
  72. ncbi Recovery of the rectoanal inhibitory reflex after restorative proctocolectomy: does it correlate with nocturnal continence?
    Naoto Saigusa
    Department of Colorectal Surgery, Cleveland Clinic Florida, Weston 33331, USA
    Dis Colon Rectum 46:168-72. 2003
    ..The aim of this study was to determine the significance of rectoanal inhibitory reflex after restorative proctocolectomy with ileal pouch-anal anastomosis for mucosal ulcerative colitis...
  73. ncbi Previous sphincter repair does not affect the outcome of repeat repair
    Pasquale Giordano
    Department of Colorectal Surgery, Cleveland Clinic Florida, Weston, Florida, USA
    Dis Colon Rectum 45:635-40. 2002
    ..As many as 60 percent of patients present with recurrent symptoms of fecal incontinence after anterior overlapping anal sphincter repair. The aim of this study was to assess the outcome of repeat overlapping anal sphincter repair...
  74. ncbi Seprafilm: a retrospective preliminary evaluation of the impact on short-term oncologic outcome in colorectal cancer
    Ioannis Oikonomakis
    Department of Colorectal Surgery, Cleveland Clinic Florida, Weston, Florida 33331, USA
    Dis Colon Rectum 45:1376-80. 2002
    ..Hyaluronate carboxymethylcellulose-based bioresorbable membrane (Seprafilm ) has been used as a method of postoperative adhesion prevention. However, its short-term effect on colorectal cancer recurrence remains unknown...