Research Topics
Genomes and GenesSpecies | Peter GallantSummaryAffiliation: University of Zurich Country: Switzerland Publications
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Detail Information
Publications
Control of growth and organ size in DrosophilaLaura A Johnston
Columbia University, Department of Genetics and Development, 701 West 168th Street, New York, NY, USA
Bioessays 24:54-64. 2002..In addition, we speculate about possible connections between the extrinsic and intrinsic pathways controlling growth and pattern...
Control of transcription by Pontin and ReptinPeter Gallant
Zoologisches Institut, Universitat Zurich, Winterthurerstrasse 190, CH 8057 Zurich, Switzerland
Trends Cell Biol 17:187-92. 2007..Here, I review recent studies that have addressed the mechanisms of transcriptional control by Pontin and Reptin...
Protein degradation, signaling, microRNAs and cancerPeter Gallant
Zoologisches Institut, Universitat Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland
Genome Biol 6:316. 2005
Myc, cell competition, and compensatory proliferationPeter Gallant
Zoologisches Institut, Universitaet Zurich, Zurich, Switzerland
Cancer Res 65:6485-7. 2005..Subversion of this mechanism may contribute to the transforming powers of Myc and possibly other oncogenes...
Myc/Max/Mad in invertebrates: the evolution of the Max networkP Gallant
Universitat Zurich, Zoologisches Institut, Winterthurerstrasse 190, 8057 Zurich, Switzerland
Curr Top Microbiol Immunol 302:235-53. 2006..This review describes the structure of invertebrate Myc/Max/Mad genes and it discusses their regulation and physiological functions, with special emphasis on their essential role in the control of cellular growth and proliferation...
Max-independent functions of Myc in Drosophila melanogasterDominik Steiger
Zoologisches Institut, Universitat Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland
Nat Genet 40:1084-91. 2008..These studies show the ability of Myc to function independently of Max in vivo and thus change the current model of Max network function...
Drosophila MycPeter Gallant
Zoologisches Institut, Universitat Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland
Adv Cancer Res 103:111-44. 2009..This review summarizes what the last decade has taught us about Myc biology in the fruit fly...
Myc interacts genetically with Tip48/Reptin and Tip49/Pontin to control growth and proliferation during Drosophila developmentPaola Bellosta
Zoologisches Institut, Universitat Zurich, Winterthurerstrasse 190, CH 8057 Zurich, Switzerland
Proc Natl Acad Sci U S A 102:11799-804. 2005..These findings indicate that dMyc:Pont complexes play an essential role in the control of cellular growth and proliferation during normal development...
Induction of apoptosis by Drosophila MycLilian Montero
Zoologisches Institut, Universitat Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland
Genesis 46:104-11. 2008..These data suggest that the control of apoptosis is a physiological function of Myc and that dMyc might play a role in the response to DNA damage...
Myc's secret life without MaxPeter Gallant
Universitat Zurich, Zoologisches Institut, Zurich, Switzerland
Cell Cycle 8:3848-53. 2009..The discovery of these Max-independent functions changes our understanding of basic Myc biology and it may affect pharmaceutical approaches to inhibiting Myc activity...
Drosophila Myc interacts with host cell factor (dHCF) to activate transcription and control growthMichael Furrer
Zoologisches Institut, Universitat Zurich, 8057 Zurich, Switzerland
J Biol Chem 285:39623-36. 2010..We therefore propose that dHCF recruits such chromatin-modifying complexes and thereby contributes to the expression of Myc targets and hence to the execution of Myc biological activities...
Getting started : an overview on raising and handling DrosophilaHugo Stocker
Institute for Molecular Systems Biology, ETH Zurich, Zurich, Switzerland
Methods Mol Biol 420:27-44. 2008..It briefly introduces the biological properties of fruit flies, describes the minimal equipment required for working with flies, and offers some basic advice for maintaining fly lines and setting up and analyzing experiments...
Whole-genome analysis reveals a strong positional bias of conserved dMyc-dependent E-boxesToby Hulf
Universitat Zurich, Zoologisches Institut, Winterthurerstrasse 190, Zurich 8057, Switzerland
Mol Cell Biol 25:3401-10. 2005..These observations raise the possibility that a subset of Myc targets share a distinct regulatory mechanism...
Drosophila myc regulates organ size by inducing cell competitionClaire de la Cova
Department of Genetics and Development, College of Physicians and Surgeons, Columbia University, 701 West 168th Street, Room 704, New York, NY 10032, USA
Cell 117:107-16. 2004..Modulating dmyc levels to create cell competition and hid-dependent cell death may be a mechanism used during normal development to control organ size...
