Research Topics
| Sebastien GagneuxSummaryAffiliation: University of Basel Country: Switzerland Publications
| Collaborators
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Detail Information
Publications
Prospective study of a serogroup X Neisseria meningitidis outbreak in northern GhanaSébastien P Gagneux
Swiss Tropical Institute, Socinstrasse 57, 4002 Basel, Switzerland
J Infect Dis 185:618-26. 2002..The occurrence of serogroup X outbreaks argues for the inclusion of this serogroup into a multivalent conjugate vaccine against N. meningitidis...
Host-pathogen coevolution in human tuberculosisSebastien Gagneux
Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute and University of Basel, Basel, Switzerland
Philos Trans R Soc Lond B Biol Sci 367:850-9. 2012..In summary, the biology and the epidemiology of human TB have been shaped by the long-standing association between MTBC and its human host...- Genetic diversification of Neisseria meningitidis during waves of colonization and disease in the meningitis belt of sub-Saharan AfricaJulia Leimkugel
Swiss Tropical Institute, Socinstr 57, 4051 Basel, Switzerland
Vaccine 25:A18-23. 2007.... - Clonal groupings in serogroup X Neisseria meningitidisSebastien Gagneux
Swiss Tropical Institute, Socinstrasse 57, 4002 Basel, Switzerland
Emerg Infect Dis 8:462-6. 2002..During the last decade, these bacteria have caused meningitis outbreaks in Niger and Ghana. These results support the development of a comprehensive conjugate vaccine that would include serogroup X polysaccharide... - Clonal waves of Neisseria colonisation and disease in the African meningitis belt: eight- year longitudinal study in northern GhanaJulia Leimkugel
Swiss Tropical Institute, Basel, Switzerland
PLoS Med 4:e101. 2007.... - Drug resistance-conferring mutations in Mycobacterium tuberculosis from Madang, Papua New GuineaMarie Ballif
Swiss Tropical and Public Health Institute, Socinstrasse 57, 4002 Basel, Switzerland
BMC Microbiol 12:191. 2012..We report for the first time M. tuberculosis mutations associated with resistance to first and second-line anti-TB drugs in Madang, PNG. A molecular cluster analysis was performed to identify M. tuberculosis transmission in that region... - Old and new selective pressures on Mycobacterium tuberculosisDaniela Brites
Swiss Tropical and Public Health Institute, Basel, Switzerland
Infect Genet Evol 12:678-85. 2012..Here we discuss how the emergence of HIV/TB and drug resistance could impact the long-term balance between MTBC and its human host, and how these changes might influence the future evolutionary trajectory of MTBC... - The heterogeneous evolution of multidrug-resistant Mycobacterium tuberculosisBorna Muller
Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland University of Basel, Basel, Switzerland
Trends Genet 29:160-9. 2013..tuberculosis. Improved knowledge of these factors will help better predict the future trajectory of MDR-TB, and contribute to the development of new tools and strategies to combat this growing public health threat... - Single nucleotide polymorphisms in Mycobacterium tuberculosis and the need for a curated databaseDavid Stucki
Swiss Tropical and Public Health Institute, Basel, Switzerland University of Basel, Switzerland
Tuberculosis (Edinb) 93:30-9. 2013..We then review some of the analytical challenges involved in processing SNP data, and end with a list of features, which should be included in a new SNP database for MTBC... - First insights into the phylogenetic diversity of Mycobacterium tuberculosis in NepalBijaya Malla
Swiss Tropical and Public Health Institute Swiss TPH, Basel, Switzerland
PLoS ONE 7:e52297. 2012..Tuberculosis (TB) is a major public health problem in Nepal. Strain variation in Mycobacterium tuberculosis may influence the outcome of TB infection and disease. To date, the phylogenetic diversity of M. tuberculosis in Nepal is unknown...