Sebastien Gagneux

Summary

Affiliation: University of Basel
Country: Switzerland

Publications

  1. pmc Host-pathogen coevolution in human tuberculosis
    Sebastien Gagneux
    Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute and University of Basel, Basel, Switzerland
    Philos Trans R Soc Lond B Biol Sci 367:850-9. 2012
  2. doi request reprint Genetic diversity in Mycobacterium tuberculosis
    Sebastien Gagneux
    Swiss Tropical and Public Health Institute Swiss TPH, University of Basel, Basel, Switzerland
    Curr Top Microbiol Immunol 374:1-25. 2013
  3. ncbi request reprint Prospective study of a serogroup X Neisseria meningitidis outbreak in northern Ghana
    Sébastien P Gagneux
    Swiss Tropical Institute, Socinstrasse 57, 4002 Basel, Switzerland
    J Infect Dis 185:618-26. 2002
  4. pmc Clonal groupings in serogroup X Neisseria meningitidis
    Sebastien Gagneux
    Swiss Tropical Institute, Socinstrasse 57, 4002 Basel, Switzerland
    Emerg Infect Dis 8:462-6. 2002
  5. ncbi request reprint An outbreak of serotype 1 Streptococcus pneumoniae meningitis in northern Ghana with features that are characteristic of Neisseria meningitidis meningitis epidemics
    Julia Leimkugel
    Swiss Tropical Institute, Basel, Switzerland
    J Infect Dis 192:192-9. 2005
  6. ncbi request reprint Genetic diversification of Neisseria meningitidis during waves of colonization and disease in the meningitis belt of sub-Saharan Africa
    Julia Leimkugel
    Swiss Tropical Institute, Socinstr 57, 4051 Basel, Switzerland
    Vaccine 25:A18-23. 2007
  7. pmc First insights into the phylogenetic diversity of Mycobacterium tuberculosis in Nepal
    Bijaya Malla
    Swiss Tropical and Public Health Institute Swiss TPH, Basel, Switzerland
    PLoS ONE 7:e52297. 2012
  8. pmc Clonal waves of Neisseria colonisation and disease in the African meningitis belt: eight- year longitudinal study in northern Ghana
    Julia Leimkugel
    Swiss Tropical Institute, Basel, Switzerland
    PLoS Med 4:e101. 2007
  9. pmc Novel Mycobacterium tuberculosis complex isolate from a wild chimpanzee
    Mireia Coscollá
    Swiss Tropical and Public Health Institute, Basel, Switzerland
    Emerg Infect Dis 19:969-76. 2013
  10. pmc Drug resistance-conferring mutations in Mycobacterium tuberculosis from Madang, Papua New Guinea
    Marie Ballif
    Swiss Tropical and Public Health Institute, Socinstrasse 57, 4002 Basel, Switzerland
    BMC Microbiol 12:191. 2012

Collaborators

Detail Information

Publications15

  1. pmc Host-pathogen coevolution in human tuberculosis
    Sebastien Gagneux
    Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute and University of Basel, Basel, Switzerland
    Philos Trans R Soc Lond B Biol Sci 367:850-9. 2012
    ..In summary, the biology and the epidemiology of human TB have been shaped by the long-standing association between MTBC and its human host...
  2. doi request reprint Genetic diversity in Mycobacterium tuberculosis
    Sebastien Gagneux
    Swiss Tropical and Public Health Institute Swiss TPH, University of Basel, Basel, Switzerland
    Curr Top Microbiol Immunol 374:1-25. 2013
    ..Given the complexity of the host-pathogen interaction in tuberculosis, systems approaches will be key to define the role of MTBC diversity in the fight against one of humankind's most important pathogens. ..
  3. ncbi request reprint Prospective study of a serogroup X Neisseria meningitidis outbreak in northern Ghana
    Sébastien P Gagneux
    Swiss Tropical Institute, Socinstrasse 57, 4002 Basel, Switzerland
    J Infect Dis 185:618-26. 2002
    ..The occurrence of serogroup X outbreaks argues for the inclusion of this serogroup into a multivalent conjugate vaccine against N. meningitidis...
  4. pmc Clonal groupings in serogroup X Neisseria meningitidis
    Sebastien Gagneux
    Swiss Tropical Institute, Socinstrasse 57, 4002 Basel, Switzerland
    Emerg Infect Dis 8:462-6. 2002
    ..During the last decade, these bacteria have caused meningitis outbreaks in Niger and Ghana. These results support the development of a comprehensive conjugate vaccine that would include serogroup X polysaccharide...
  5. ncbi request reprint An outbreak of serotype 1 Streptococcus pneumoniae meningitis in northern Ghana with features that are characteristic of Neisseria meningitidis meningitis epidemics
    Julia Leimkugel
    Swiss Tropical Institute, Basel, Switzerland
    J Infect Dis 192:192-9. 2005
    ..These epidemics are generally caused by Neisseria meningitidis, an organism that is considered to be uniquely capable of causing meningitis epidemics...
  6. ncbi request reprint Genetic diversification of Neisseria meningitidis during waves of colonization and disease in the meningitis belt of sub-Saharan Africa
    Julia Leimkugel
    Swiss Tropical Institute, Socinstr 57, 4051 Basel, Switzerland
    Vaccine 25:A18-23. 2007
    ....
  7. pmc First insights into the phylogenetic diversity of Mycobacterium tuberculosis in Nepal
    Bijaya Malla
    Swiss Tropical and Public Health Institute Swiss TPH, Basel, Switzerland
    PLoS ONE 7:e52297. 2012
    ..Tuberculosis (TB) is a major public health problem in Nepal. Strain variation in Mycobacterium tuberculosis may influence the outcome of TB infection and disease. To date, the phylogenetic diversity of M. tuberculosis in Nepal is unknown...
  8. pmc Clonal waves of Neisseria colonisation and disease in the African meningitis belt: eight- year longitudinal study in northern Ghana
    Julia Leimkugel
    Swiss Tropical Institute, Basel, Switzerland
    PLoS Med 4:e101. 2007
    ....
  9. pmc Novel Mycobacterium tuberculosis complex isolate from a wild chimpanzee
    Mireia Coscollá
    Swiss Tropical and Public Health Institute, Basel, Switzerland
    Emerg Infect Dis 19:969-76. 2013
    ..Exploring this diversity is crucial to the understanding of the biology and evolutionary history of this widespread infectious disease...
  10. pmc Drug resistance-conferring mutations in Mycobacterium tuberculosis from Madang, Papua New Guinea
    Marie Ballif
    Swiss Tropical and Public Health Institute, Socinstrasse 57, 4002 Basel, Switzerland
    BMC Microbiol 12:191. 2012
    ..We report for the first time M. tuberculosis mutations associated with resistance to first and second-line anti-TB drugs in Madang, PNG. A molecular cluster analysis was performed to identify M. tuberculosis transmission in that region...
  11. pmc Single nucleotide polymorphisms in Mycobacterium tuberculosis and the need for a curated database
    David Stucki
    Swiss Tropical and Public Health Institute, Basel, Switzerland
    Tuberculosis (Edinb) 93:30-9. 2013
    ..We then review some of the analytical challenges involved in processing SNP data, and end with a list of features, which should be included in a new SNP database for MTBC...
  12. doi request reprint Evaluation of Customised Lineage-Specific Sets of MIRU-VNTR Loci for Genotyping Mycobacterium tuberculosis Complex Isolates in Ghana
    Adwoa Asante-Poku
    Bacteriology Department, Noguchi Memorial Institute for Medical Research, University of Ghana, Legon, Ghana Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland University of Basel, Basel, Switzerland
    PLoS ONE 9:e92675. 2014
    ..Here, we evaluated the discriminatory power of a "customized MIRU12" loci format proposed previously by Comas et al. based on the standard 24 loci defined by Supply et al. for VNTR-typing of MTBC in Ghana...
  13. pmc The heterogeneous evolution of multidrug-resistant Mycobacterium tuberculosis
    Borna Muller
    Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland University of Basel, Basel, Switzerland
    Trends Genet 29:160-9. 2013
    ..tuberculosis. Improved knowledge of these factors will help better predict the future trajectory of MDR-TB, and contribute to the development of new tools and strategies to combat this growing public health threat...
  14. pmc Old and new selective pressures on Mycobacterium tuberculosis
    Daniela Brites
    Swiss Tropical and Public Health Institute, Basel, Switzerland
    Infect Genet Evol 12:678-85. 2012
    ..Here we discuss how the emergence of HIV/TB and drug resistance could impact the long-term balance between MTBC and its human host, and how these changes might influence the future evolutionary trajectory of MTBC...
  15. pmc Two new rapid SNP-typing methods for classifying Mycobacterium tuberculosis complex into the main phylogenetic lineages
    David Stucki
    Swiss Tropical and Public Health Institute, Basel, Switzerland
    PLoS ONE 7:e41253. 2012
    ..Furthermore, both methods are rapid, flexible and comparably inexpensive...