Jean Louis Frossard

Summary

Affiliation: University Hospital
Country: Switzerland

Publications

  1. doi request reprint Acute pancreatitis
    Jean Louis Frossard
    Division de Gastroenterologie, Hopitaux Universitaires de Geneve, Geneva, Switzerland
    Lancet 371:143-52. 2008
  2. pmc An unusual digestive foreign body
    Jean Louis Frossard
    Department of Internal Medicine, Division of Gastroenterology, Hopital Cantonal Universitaire de Geneve, Geneva, Switzerland
    Case Rep Gastroenterol 5:201-5. 2011
  3. pmc Ectopic varices and collaterals development after band ligation treatment in a patient with portal hypertension
    Jean Louis Frossard
    Division of Gastroenterology and Hepatology, Geneva University Hospital, Geneva, Switzerland
    Case Rep Gastroenterol 2:380-3. 2008
  4. pmc Charcot's triad
    Jean Louis Frossard
    Service of Gastroenterology and Hepatology, Geneva University Hospitals, Rue Gabrielle Perret Gentil 24, 1211 Geneva, Switzerland
    Int J Emerg Med 4:18. 2011
  5. ncbi request reprint The role of transient elastography in the detection of liver disease in patients with chronic pancreatitis
    Jean Louis Frossard
    Service de gastroentérologie et hepatologie, Hopital Cantonal Universitaire de Geneve, Geneve, Switzerland
    Liver Int 33:1121-7. 2013
  6. pmc Computed tomography colonography imaging of pneumatosis intestinalis after hyperbaric oxygen therapy: a case report
    Jean Louis Frossard
    Service of Gastroenterology and Hepatology, Geneva University Hospital, Rue Gabrielle Perret Gentil 4, 1211 Geneve 14, Switzerland
    J Med Case Reports 5:375. 2011
  7. ncbi request reprint [Barrett's esophagus: epidemiology diagnosis and treatment in 2005]
    J L Frossard
    Division de Gastroenterologie, Hôpital cantonal universitaire 1211 Genève 14
    Rev Med Suisse 1:2037-8, 2040-1. 2005
  8. pmc Concomitant autoimmune and genetic pancreatitis leads to severe inflammatory conditions
    Jean Louis Frossard
    Division de gastroentérologie et hépatologie, Geneva University Hospital, Geneva 1205, Switzerland
    World J Gastroenterol 14:2596-8. 2008
  9. ncbi request reprint Soluble CD40 ligand in prediction of acute severe pancreatitis
    Jean Louis Frossard
    Division of Gastroenterology, Geneva University Hospital, 1211 Geneve 14, Switzerland
    World J Gastroenterol 12:1613-6. 2006
  10. ncbi request reprint Pathophysiology of acute pancreatitis: a multistep disease
    Jean Louis Frossard
    Division of Gastroenterology and Hepatology, Geneva University Hospital, Rue Micheli du Crest, 1211 Geneve 14
    Acta Gastroenterol Belg 66:166-73. 2003

Detail Information

Publications69

  1. doi request reprint Acute pancreatitis
    Jean Louis Frossard
    Division de Gastroenterologie, Hopitaux Universitaires de Geneve, Geneva, Switzerland
    Lancet 371:143-52. 2008
    ..Improved understanding of pathophysiology and better assessments of disease severity should ameliorate the management and outcome of this complex disease...
  2. pmc An unusual digestive foreign body
    Jean Louis Frossard
    Department of Internal Medicine, Division of Gastroenterology, Hopital Cantonal Universitaire de Geneve, Geneva, Switzerland
    Case Rep Gastroenterol 5:201-5. 2011
    ..The current case illustrates successful endoscopic retrieval of a proximally located foreign body in a particular legal situation where physicians had to work closely with police officers and court members...
  3. pmc Ectopic varices and collaterals development after band ligation treatment in a patient with portal hypertension
    Jean Louis Frossard
    Division of Gastroenterology and Hepatology, Geneva University Hospital, Geneva, Switzerland
    Case Rep Gastroenterol 2:380-3. 2008
    ..Moreover, esophageal band ligation may interfere with the collateral web. We here report a case of an ectopic duodenal varix and the development of a large collaterals web that appeared after band ligation...
  4. pmc Charcot's triad
    Jean Louis Frossard
    Service of Gastroenterology and Hepatology, Geneva University Hospitals, Rue Gabrielle Perret Gentil 24, 1211 Geneva, Switzerland
    Int J Emerg Med 4:18. 2011
    ..Acute suppurative cholangitis may be fatal unless adequate biliary drainage is obtained in a timely manner. The association of fever and rapid onset of jaundice in elderly patients should always make physicians think of cholangitis...
  5. ncbi request reprint The role of transient elastography in the detection of liver disease in patients with chronic pancreatitis
    Jean Louis Frossard
    Service de gastroentérologie et hepatologie, Hopital Cantonal Universitaire de Geneve, Geneve, Switzerland
    Liver Int 33:1121-7. 2013
    ..The current study was aimed to assess the diagnostic performance of liver stiffness measurement for the determination of fibrosis stage in patients with chronic pancreatitis...
  6. pmc Computed tomography colonography imaging of pneumatosis intestinalis after hyperbaric oxygen therapy: a case report
    Jean Louis Frossard
    Service of Gastroenterology and Hepatology, Geneva University Hospital, Rue Gabrielle Perret Gentil 4, 1211 Geneve 14, Switzerland
    J Med Case Reports 5:375. 2011
    ..abstract:..
  7. ncbi request reprint [Barrett's esophagus: epidemiology diagnosis and treatment in 2005]
    J L Frossard
    Division de Gastroenterologie, Hôpital cantonal universitaire 1211 Genève 14
    Rev Med Suisse 1:2037-8, 2040-1. 2005
    ..It can be applied for lesions detected at an early stage only (i.e., usually detected in the setting of a surveillance program). Therefore, non-operability is not considered as an exclusion criteria of such programs anymore...
  8. pmc Concomitant autoimmune and genetic pancreatitis leads to severe inflammatory conditions
    Jean Louis Frossard
    Division de gastroentérologie et hépatologie, Geneva University Hospital, Geneva 1205, Switzerland
    World J Gastroenterol 14:2596-8. 2008
    ..We here describe a case of chronic pancreatitis with an onset at a very young age in which a mutation of the PRSS1 and several features of autoimmune pancreatitis were identified...
  9. ncbi request reprint Soluble CD40 ligand in prediction of acute severe pancreatitis
    Jean Louis Frossard
    Division of Gastroenterology, Geneva University Hospital, 1211 Geneve 14, Switzerland
    World J Gastroenterol 12:1613-6. 2006
    ..To assess the early predictability of the soluble CD40L (sCD40L) in pancreatitis severity...
  10. ncbi request reprint Pathophysiology of acute pancreatitis: a multistep disease
    Jean Louis Frossard
    Division of Gastroenterology and Hepatology, Geneva University Hospital, Rue Micheli du Crest, 1211 Geneve 14
    Acta Gastroenterol Belg 66:166-73. 2003
  11. ncbi request reprint Effect of hyperthermia on NF-kappaB binding activity in cerulein-induced acute pancreatitis
    J L Frossard
    Division of Gastroenterology, Geneva University Hospital, 1211 Geneva 14, Switzerland
    Am J Physiol Gastrointest Liver Physiol 280:G1157-62. 2001
    ..These results suggest that hyperthermia decreases the severity of cerulein-induced pancreatitis by decreasing cytokine expression in the pancreas through the modulation of NF-kappaB activity...
  12. ncbi request reprint Water-immersion sigmoidoscopy to treat acute GI bleeding in the perioperative period after surgical colorectal anastomosis
    Jean Louis Frossard
    Service of Gastroenterology, Geneva University Hospital, Geneva, Switzerland
    Gastrointest Endosc 71:167-70. 2010
    ..The early treatment includes surgery or endoscopy, the latter being subject to complications associated with air insufflation and associated perforation...
  13. ncbi request reprint Early prediction in acute pancreatitis: the contribution of amylase and lipase levels in peritoneal fluid
    J L Frossard
    Division of Gastroenterology, Geneva University Hospital, Geneva, Switzerland
    JOP 1:36-45. 2000
    ..Predicting the severity of acute pancreatitis early in the course of the disease is still difficult...
  14. ncbi request reprint [Cystic lesions of the pancreas: towards a standardized diagnostic approach?]
    Jean Louis Frossard
    Division de gastroentérologie et hépatologie, Hopital Cantonal Universitaire de Geneve, 1211 Geneve 14
    Rev Med Suisse Romande 122:65-9. 2002
  15. doi request reprint Role of CCL-2, CCR-2 and CCR-4 in cerulein-induced acute pancreatitis and pancreatitis-associated lung injury
    Jean Louis Frossard
    Service of Gastroenterology and Hepatology, Geneva University Hospital, Geneva, Switzerland
    J Clin Pathol 64:387-93. 2011
    ..To address the role of CCL-2, CCR-2 and CCR-4 that attracts leucocytes cells in inflamed tissues, pancreatitis was induced by administering supramaximal doses of cerulein in mice that do not express CCL-2, CCR-2 or CCR-4...
  16. ncbi request reprint Cd40 ligand-deficient mice are protected against cerulein-induced acute pancreatitis and pancreatitis-associated lung injury
    J L Frossard
    Division of Gastroenterology, Geneva University Hospitals, Rue Micheli du Crest, 1211 Geneva 14, Switzerland
    Gastroenterology 121:184-94. 2001
    ....
  17. ncbi request reprint Erythromycin intravenous bolus infusion in acute upper gastrointestinal bleeding: a randomized, controlled, double-blind trial
    Jean Louis Frossard
    Division of Gastroenterology and Hepatology, Geneva University Hospitals, Geneve, Switzerland
    Gastroenterology 123:17-23. 2002
    ..Erythromycin, a motilin agonist, induces gastric emptying. We investigated whether an intravenous bolus infusion of erythromycin would improve the yield of endoscopy in these patients...
  18. ncbi request reprint Natural history of long-term lung injury in mouse experimental pancreatitis
    Jean Louis Frossard
    Division of Gastroenterology, Geneva University Hospital, Switzerland
    Crit Care Med 30:1541-6. 2002
    ..In this study, we examined the natural history of pancreatitis-associated lung injury during an entire week...
  19. ncbi request reprint [Biliary, pancreatic and systemic diseases associated with IgG4]
    Jean Louis Frossard
    Division de gastroentérologie et hépatologie, HUG, 1211 Geneve 14
    Rev Med Suisse 4:1856-8. 2008
    ..This paper is aimed at reviewing all new aspects of diseases associated with high levels of IgG4...
  20. ncbi request reprint Neutrophil depletion--but not prevention of Kupffer cell activation--decreases the severity of cerulein-induced acute pancreatitis
    Catherine M Pastor
    Laboratoire de Physiopathologie Hépatique et Imagerie Moléculaire, Hopitaux Universitaires de Geneve, 24 Rue Micheli du Crest, 1205 Geneva, Switzerland
    World J Gastroenterol 12:1219-24. 2006
    ..To determine whether neutrophil depletion and Kupffer cell inhibition might combine their protective effects to decrease the severity of acute pancreatitis...
  21. ncbi request reprint Role of Toll-like receptor 4 on pancreatic and pulmonary injury in a mice model of acute pancreatitis associated with endotoxemia
    Catherine M Pastor
    Division of Gastroenterology and Hepatology, Department of Pediatrics MC, Geneva University Hospitals, Geneva, Switzerland
    Crit Care Med 32:1759-63. 2004
    ....
  22. ncbi request reprint Proteomic profiling in an animal model of acute pancreatitis
    Vanessa Fétaud
    Biomedical Proteomics Research Group, Department of Bioinformatics and Structural Biology, Geneva Faculty of Medicine, Geneva, Switzerland
    Proteomics 8:3621-31. 2008
    ..These results showed the interest of proteomic analysis to identify changes characterizing pancreatic tissue damage and, therefore, to highlight new potential biomarkers of AP...
  23. doi request reprint Role of proteomics to differentiate between benign and potentially malignant pancreatic cysts
    Aurora Cuoghi
    Biomedical Proteomics Research Group, Department of Bioinformatics and Structural Biology, Faculty of Medicine, Geneva University, Geneva, Switzerland
    J Proteome Res 10:2664-70. 2011
    ..Results from this study indicate that proteomic analysis of cyst fluid could provide reliable candidates for developing new biomarkers for the preoperative management of malignant and premalignant pancreatic cysts...
  24. ncbi request reprint Role of macrophage inflammatory peptide-2 in cerulein-induced acute pancreatitis and pancreatitis-associated lung injury
    Catherine M Pastor
    Division of Gastroenterology and Hepatology, Geneva University Hospital, Geneva, Switzerland
    Lab Invest 83:471-8. 2003
    ..These results show that MIP-2 plays a key role in the pathophysiology of acute pancreatitis and that MIP-2 blockade may improve the outcome of the disease...
  25. ncbi request reprint Severe acute pancreatitis and reduced acinar cell apoptosis in the exocrine pancreas of mice deficient for the Cx32 gene
    Jean Louis Frossard
    Divisions of Gastroenterology, University Hospitals, Geneva, Switzerland
    Gastroenterology 124:481-93. 2003
    ....
  26. doi request reprint Proteomic analysis of heat shock-induced protection in acute pancreatitis
    Vanessa Fetaud-Lapierre
    Department of Bioinformatics and Structural Biology, Geneva Faculty of Medicine, Geneva, Switzerland
    J Proteome Res 9:5929-42. 2010
    ....
  27. ncbi request reprint Time course of lung injury in rat acute pancreatitis
    Denis R Morel
    Hopitaux Universitaires de Geneve, division d investigations anesthésiologiques, Geneva, Switzerland
    Intensive Care Med 32:1872-80. 2006
    ....
  28. ncbi request reprint Magnetic resonance imaging with hepatospecific contrast agents in cirrhotic rat livers
    Corinne Planchamp
    Département de Radiologie and Division de Gastroentérologie, Hopitaux Universitaires de Geneve, Geneva, Switzerland
    Invest Radiol 40:187-94. 2005
    ..Consequently, the aim of our study was to measure the hepatic SI enhancement during Gd-BOPTA perfusion as well as the Oatp and Mrp2 expression in normal and cirrhotic livers...
  29. pmc Autologous bone marrow mononuclear cell transplantation in patients with decompensated alcoholic liver disease: a randomized controlled trial
    Laurent Spahr
    Division of Gastroenterology and Hepatology, University Hospitals and Faculty of Medicine, Geneva, Switzerland
    PLoS ONE 8:e53719. 2013
    ..We assessed whether autologous bone marrow mononuclear cell transplantation (BMMCT) improved liver function in decompensated ALD...
  30. ncbi request reprint Analysis of the pancreatic low molecular weight proteome in an animal model of acute pancreatitis
    Olivier Lassout
    Clinical Proteomics Laboratory, Department of Genetics and Laboratory Medicine, Geneva University Hospitals, Biomedical Proteomics Research Group, Department of Bioinformatics and Structural Biology, Geneva Faculty of Medicine, Geneva, Switzerland
    J Proteome Res 9:4535-44. 2010
    ..These data suggest that peptidomic analysis is a complementary approach to proteomics for investigating pathobiological processes involved in acute pancreatitis...
  31. doi request reprint Delayed production of IL-18 in lungs and pancreas of rats with acute pancreatitis
    Catherine M Pastor
    Laboratoire de Physiopathologie Hépatique et Imagerie Moléculaire, Hopitaux Universitaires de Geneve, Geneve, Suisse Catherine Pastor hcuge ch
    Pancreatology 10:752-7. 2010
    ..However, the profile of IL-18 expression in the pancreas and lung is unknown, and the aim of our study was to investigate such expression in rats with pancreatitis...
  32. doi request reprint Time-course proteomic analysis of taurocholate-induced necrotizing acute pancreatitis
    Vanessa Fetaud-Lapierre
    Biomedical Proteomics Research Group, Department of Human Protein Science, Geneva Faculty of Medicine, Geneva, Switzerland
    J Proteomics 85:12-27. 2013
    ....
  33. pmc Epidural anaesthesia restores pancreatic microcirculation and decreases the severity of acute pancreatitis
    Alp Demirag
    Surgical Research Unit, Department of Surgery, University Hospital Geneva, 24, Rue Micheli du Crest, 1211, Geneva 14, Switzerland
    World J Gastroenterol 12:915-20. 2006
    ..To investigate the effect of epidural anaesthesia (EA) on pancreatic microcirculation during acute pancreatitis (AP)...
  34. ncbi request reprint A 3-month course of long-acting repeatable octreotide (sandostatin LAR) improves portal hypertension in patients with cirrhosis: a randomized controlled study
    Laurent Spahr
    Transplantation Unit, University Hospital, Geneva, Switzerland
    Am J Gastroenterol 102:1397-405. 2007
    ..Information on long-term effects of octreotide is limited and controversial. We evaluated portal and systemic hemodynamics following a prolonged administration of long-acting octreotide in patients with cirrhosis...
  35. ncbi request reprint Low dose oral cannabinoid therapy reduces progression of atherosclerosis in mice
    Sabine Steffens
    Division of Cardiology, Department of Medicine, Foundation for Medical Research, University Hospital, Faculty of Medicine, 1211 Geneva, Switzerland
    Nature 434:782-6. 2005
    ..Thus, THC or cannabinoids with activity at the CB2 receptor may be valuable targets for treating atherosclerosis...
  36. ncbi request reprint Soluble TNF-R1, but not tumor necrosis factor alpha, predicts the 3-month mortality in patients with alcoholic hepatitis
    Laurent Spahr
    Gastroenterology and Hepatology, University Hospital, Geneva, Switzerland
    J Hepatol 41:229-34. 2004
    ..In patients with AH, we determined the prognostic value of TNF alpha, sTNF-R1, and lipopolysaccharide binding protein (LBP) and CD14, both involved in endotoxemia-associated inflammation...
  37. pmc Expression of the bile acid receptor FXR in Barrett's esophagus and enhancement of apoptosis by guggulsterone in vitro
    Andrea De Gottardi
    Division of Gastroenterology, University Hospital, Micheli du Crest 24, 1205 Geneva, Switzerland
    Mol Cancer 5:48. 2006
    ..The aim of this study was to assess the expression of bile acid receptors in the esophagus (normal, esophagitis, Barrett's esophagus and adenocarcinoma) and to investigate their possible function...
  38. ncbi request reprint Why clinical trials might succeed in acute pancreatitis when they failed in septic shock
    Jean Louis Frossard
    Division d Hépatologie et de Gastro entérologie and Département de Chirurgie Digestive, Hopital Universitaire de Geneve, Geneve, Switzerland
    JOP 4:11-6. 2003
  39. ncbi request reprint Effect of hyperthermic preconditioning on cold preserved rat portal veins
    Catherine M Pastor
    Division d Hépatologie et de Gastro entérologie, Hopital Cantonal Universitaire de Geneve, Rue Micheli du Crest, 24, 1211 Geneva 14, Switzerland
    J Hepatol 37:640-7. 2002
    ..We then studied, after cold preservation, the in vitro contractile responses of rat portal veins (RPV) isolated from normal rats or from rats previously subjected to hyperthermia...
  40. pmc Age, smoking and overweight contribute to the development of intestinal metaplasia of the cardia
    Christian Felley
    Service of Gastroenterology, University Hospital, 1000 Lausanne, Switzerland
    World J Gastroenterol 18:2076-83. 2012
    ..To assess the role of Helicobacter pylori (H. pylori), gastroesophageal reflux disease (GERD), age, smoking and body weight on the development of intestinal metaplasia of the gastric cardia (IMC)...
  41. ncbi request reprint An unusual case of gastric heterotopic pancreas
    Laura Rubbia-Brandt
    Division of Clinical Pathology, Clinic of Digestive Surgery, Geneva University Hospitals, Geneva, Switzerland
    JOP 5:484-7. 2004
    ..Submucosal lesions of the gastrointestinal tract represent a diagnostic challenge for the physician. Endoscopic ultrasonography may provide useful information before deciding on therapeutic strategy...
  42. ncbi request reprint Early prediction of acute pancreatitis: prospective study comparing computed tomography scans, Ranson, Glascow, Acute Physiology and Chronic Health Evaluation II scores, and various serum markers
    John H Robert
    Department of Digestive Surgery, Geneva University Hospitals, Rue Micheli du Crest, 1211 Geneva 14, Switzerland
    World J Surg 26:612-9. 2002
    ..None of the parameters tested achieved sufficient predictability when used alone. Serum albumin plus extrapancreatic fluid collections comprise the best indicator of severity at the time of admission...
  43. ncbi request reprint Initial cholecystectomy vs sequential common duct endoscopic assessment and subsequent cholecystectomy for suspected gallstone migration: a randomized clinical trial
    Pouya Iranmanesh
    Division of Digestive Surgery, Department of Surgery, Geneva University Hospital and Faculty of Medicine, Geneva, Switzerland2Division of Transplant Surgery, Department of Surgery, Geneva University Hospital and Faculty of Medicine, Geneva, Switzerland3He
    JAMA 312:137-44. 2014
    ..Many stones migrate spontaneously into the duodenum, making preoperative common duct investigations unnecessary...
  44. ncbi request reprint Association between lymphoepithelial cysts of the pancreas and HIV infection
    Benoît Bédat
    Department of Surgery, Division of Visceral Surgery, Geneva University Hospitals, rue Gabrielle Perret Gentil, 4, 1211 Geneva 14, Switzerland
    Pancreatology 12:61-4. 2012
    ..To report the association of lymphoepithelial cysts (LEC) of the pancreas with Human Immunodeficiency Virus (HIV) infection. An association between LEC and HIV infection is already established in the parotid gland (PG)...
  45. ncbi request reprint Experimental acute pancreatitis: new insights into the pathophysiology
    Jean Louis Frossard
    Division de Gastro enterologie et d Hepatologie, Hopital Cantonal Universitaire de Geneve, Geneva, Switzerland
    Front Biosci 7:d275-87. 2002
    ....
  46. ncbi request reprint A new method of biliary sampling for cytopathological examination during endoscopic retrograde cholangiography
    Jean Marc Dumonceau
    Service of Gastroenterology and Hepatology, Geneva University Hospitals, Geneva, Switzerland
    Am J Gastroenterol 102:550-7. 2007
    ..We compared the cellular and diagnostic yields of a new sampling method (using stricture dilation and a grasping basket) with those of brushing...
  47. ncbi request reprint Function of both sinusoidal and canalicular transporters controls the concentration of organic anions within hepatocytes
    Corinne Planchamp
    Laboratoire de Physiopathologie Hépatique et Imagerie Moléculaire, Hopitaux Universitaires de Geneve, Rue Micheli du Crest, 24, 1205 Geneva, Switzerland
    Mol Pharmacol 71:1089-97. 2007
    ..These results highlight that the function of both sinusoidal and canalicular transporters is important to determine the concentration of organic anions within hepatocytes...
  48. ncbi request reprint Allopurinol, oxidative stress and intestinal permeability in patients with cirrhosis: an open-label pilot study
    Laurent Spahr
    Gastroenterology and Hepatology, University Hospital, Geneva, Switzerland
    Liver Int 27:54-60. 2007
    ..Experimentally, allopurinol, a xanthine oxidase inhibitor, reduces enterocytes' damage and bacterial translocation...
  49. pmc Endothelial nitric oxide synthase regulation is altered in pancreas from cirrhotic rats
    Jean Louis Frossard
    Division de Gastroenterologie, Hôpitaux Universitaires de GenevePhilippe Morel, Departement de Chirurgie, Hopitaux Universitaires de Geneve, Switzerland
    World J Gastroenterol 12:228-33. 2006
    ....
  50. doi request reprint Granulocyte-colony stimulating factor induces proliferation of hepatic progenitors in alcoholic steatohepatitis: a randomized trial
    Laurent Spahr
    Department of Gastroenterology and Hepatology, University Hospital, Geneva, Switzerland
    Hepatology 48:221-9. 2008
    ..003). Changes in Ki67+/cytokeratin 7+ cells correlated with changes in CD34+ cells (r = 0.65, P < 0.03). Neutrophils and histological changes were similar in both groups...
  51. ncbi request reprint Performance of endosonography-guided fine needle aspiration and biopsy in the diagnosis of pancreatic cystic lesions
    Jean Louis Frossard
    Division of Gastroenterology, Geneva University Hospital, Geneva, Switzerland
    Am J Gastroenterol 98:1516-24. 2003
    ..The aim of our study was to assess the performance of endoscopic ultrasonography (EUS) and EUS-guided fine needle aspiration (FNA) in the diagnosis of pancreatic cystic lesions...
  52. doi request reprint Value of contrast-enhanced 18F-fluorodeoxyglucose positron emission tomography/computed tomography in detection and presurgical assessment of pancreatic cancer: a prospective study
    Nicolas C Buchs
    Clinic for Visceral and Transplantation Surgery, Department of Surgery, University Hospitals of Geneva, Switzerland
    J Gastroenterol Hepatol 26:657-62. 2011
    ..The aim of this study is to investigate the performance of FDG PET associated with contrast-enhanced CT in detection of pancreatic cancer...
  53. ncbi request reprint Pancreatitis-associated acute lung injury: new insights
    Catherine M Pastor
    Departement de Radiologie, Hopitaux Universitaires de Geneve, 1211 Geneva 14, Switzerland
    Chest 124:2341-51. 2003
  54. ncbi request reprint The role of CFTR and SPINK-1 mutations in pancreatic disorders in HIV-positive patients: a case-control study
    Christian Felley
    Division of Gastroenterology, and Institute of Microbiology, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
    AIDS 18:1521-7. 2004
    ..This study will evaluate the frequency of CFTR mutations and SPINK-1 polymorphisms in HIV-positive patients with clinical pancreatitis or asymptomatic elevation of serum pancreatic enzymes...
  55. ncbi request reprint Opposite regulation of endothelial NO synthase by HSP90 and caveolin in liver and lungs of rats with hepatopulmonary syndrome
    Jean Louis Frossard
    Laboratoire de Physiopathologie Hépatique et Imagerie Moléculaire, Hopitaux Universitaires de Geneve, Rue Micheli du Crest, 24, 1205 Geneva, Switzerland
    Am J Physiol Gastrointest Liver Physiol 293:G864-70. 2007
    ..Such opposite posttranslational regulation of eNOS by regulatory proteins may explain in part the pulmonary overproduction of NO and the hepatic NO defect in rats with hepatopulmonary syndrome...
  56. ncbi request reprint Hsp70 does not mediate the hyperthermia-associated hyporesponsiveness to angiotensin in isolated rat portal veins
    Jean Louis Frossard
    Division de Gastroenterologie, Hopitaux Universitaires de Geneve, Geneva, Switzerland
    Life Sci 78:41-6. 2005
    ..In conclusion, hyperthermia increases Hsp70 expression but does not mediate the decreased response to AT(II). Hsp70 overexpression has no effect on the actin-myosin interaction in vascular smooth muscle...
  57. doi request reprint Hepatic regeneration is decreased in a rat model of sinusoidal obstruction syndrome
    Eduardo Schiffer
    Laboratoire de Physiopathologie Hépatique et Imagerie Moléculaire, Hopitaux Universitaires de Geneve, Geneva 1205, Switzerland
    J Surg Oncol 99:439-46. 2009
    ..However, the drug may severely injure hepatic sinusoids, inducing a sinusoidal obstruction syndrome in non-tumoral parenchyma with a risk of decreased regeneration in the remnant liver following partial hepatectomy...
  58. ncbi request reprint [Autoimmune pancreatitis]
    Alain Vonlaufen
    Service de gastro entérologie et d hépatologie, Département de mécecine interne, HUG, 1211 Geneve 14
    Rev Med Suisse 6:1662-6. 2010
    ..In order to avoid unnecessary resections for an otherwise benign and easily treatable condition, it is urgent to refine diagnostic criteria and to reach an international consensus...
  59. ncbi request reprint Recurrent Clostridium difficile infections: the importance of the intestinal microbiota
    Marie Céline Zanella Terrier
    Marie Céline Zanella Terrier, Martine Louis Simonet, Service of General Internal Medicine, Geneva University Hospital, 1211 Geneva, Switzerland
    World J Gastroenterol 20:7416-23. 2014
    ..This article focuses on current guidelines for CDI treatment, the role of intestinal microbiota in CDI recurrence and current evidence about FMT efficacy, adverse effects and acceptability. ..
  60. pmc Combined written and oral information prior to gastrointestinal endoscopy compared with oral information alone: a randomized trial
    Christian Felley
    Division of Gastroenterology and Hepatology, University Hospitals, and University of Geneva, Geneva, Switzerland
    BMC Gastroenterol 8:22. 2008
    ..Little is known about how to most effectively deliver relevant information to patients scheduled for endoscopy...
  61. ncbi request reprint [Drug-induced pancreatitis]
    Thai Nguyen-Tang
    Service de gastroentérologie et hepatologie, HUG, 1211 Geneve 14
    Rev Med Suisse 3:1942, 1944-7. 2007
    ..The degree of the evidence is classified by the strength of the association (definite, probable and possible) and the number of reported cases. The prognosis is in most cases good, but rare cases of death have been reported...
  62. ncbi request reprint Colorectal anastomotic stenosis after elective laparoscopic sigmoidectomy for diverticular disease: a prospective evaluation of 68 patients
    Patrick Ambrosetti
    Clinique Générale Beaulieu, 4, rue Emile Yung, 1205, Geneva, Switzerland
    Dis Colon Rectum 51:1345-9. 2008
    ..This prospective study was designed to find the incidence of symptomatic anastomotic stenosis after elective laparoscopic sigmoidectomy for diverticular disease...
  63. pmc Clopidogrel and proton pump inhibitors--where do we stand in 2012?
    Michael D Drepper
    Division of Gastroenterology, Department of Internal Medicine, Geneva University Hospital, 14 Geneva CH 1211, Switzerland
    World J Gastroenterol 18:2161-71. 2012
    ....
  64. pmc Primary aortodigestive fistula: a rare and potentially lethal cause of gastrointestinal hemorrhage
    Saskia Ditisheim
    Department of Gastroenterology and Hepatology, University Hospital of Geneva, Geneva, Switzerland
    Case Rep Gastroenterol 5:428-32. 2011
    ..We report on the case of a 79-year-old patient with a PAF who was admitted for hematochezia and melena. The PAF was suspected during upper gastrointestinal endoscopy and confirmed by CT angiography...
  65. ncbi request reprint [Recurrent Clostridium difficile infections: the importance of the intestinal microbiota]
    Marie Céline Zanella Terrier
    Service de médecine interne générale, Departement de Medecine Interne, réhabilitation et gériatrie, HUG, 1211 Geneve 14
    Rev Med Suisse 9:1898, 1900-4. 2013
    ..Further studies are needed to confirm its effectiveness, determine the long-term consequences as well as good administration practices...
  66. pmc Intramural hematoma of the esophagus
    Dahlia Thao Cao
    Department of Medical Specialties, Gastroenterology and Hepatology Division, University Hospitals and Faculty of Medicine of Geneva, Geneva, Switzerland
    Case Rep Gastroenterol 6:510-7. 2012
    ..The treatment is conservative and the prognosis usually excellent with complete resolution within a few weeks...
  67. doi request reprint Pictorial review: rectosigmoid endometriosis on MRI with gel opacification after rectosigmoid colon cleansing
    Pierre Loubeyre
    Department of Imaging, Geneva University Hospitals, Geneva, Switzerland
    Clin Imaging 36:295-300. 2012
    ..In this regard, the use of high-frequency echoendoscope may be needed. Recognition of rectosigmoid endometriosis is important to establish a correct diagnosis and provide counseling and appropriate therapy...