L E French

Summary

Affiliation: University of Geneva
Country: Switzerland

Publications

  1. ncbi request reprint Identification of clonal T cells in the blood of patients with systemic sclerosis: positive correlation with response to photopheresis
    L E French
    Department of Dermatology, Geneva University Hospital, 24, Rue Micheli du Crest, CH 1211 Genève 14 Switzerland
    Arch Dermatol 137:1309-13. 2001
  2. ncbi request reprint Modulation of clusterin gene expression in the rat mammary gland during pregnancy, lactation, and involution
    L E French
    Division of Dermatology, University Medical Center, Geneva, Switzerland
    Biol Reprod 55:1213-20. 1996
  3. ncbi request reprint Eccrine syringofibroadenoma in a patient with erosive palmoplantar lichen planus
    L E French
    Department of Dermatology, Geneva University Hospital, Switzerland
    Dermatology 195:399-401. 1997
  4. ncbi request reprint Regression of multifocal, skin-restricted, CD30-positive large T-cell lymphoma with interferon alfa and bexarotene therapy
    L E French
    Department of Dermatology, University of Pennsylvania, Philadelphia, USA
    J Am Acad Dermatol 45:914-8. 2001
  5. ncbi request reprint Post-stripping sclerodermiform dermatitis
    L E French
    Department Hospitalo Universitaire Romand de Dermatologie Geneva Lausanne, Geneva, Switzerland
    Arch Dermatol 135:1387-91. 1999
  6. ncbi request reprint Incidence of transient acantholytic dermatosis (Grover's disease) in a hospital setting
    L E French
    Department of Dermatology DHURDV, HCU, Geneva, Switzerland
    Dermatology 198:410-1. 1999
  7. ncbi request reprint Selective expression of FLIP in malignant melanocytic skin lesions
    R R Bullani
    Department of Dermatology, Geneva University Medical School, Switzerland
    J Invest Dermatol 117:360-4. 2001
  8. ncbi request reprint Therapeutic advances in biological response modifiers in the treatment of cutaneous T-cell lymphoma
    C C Vittorio
    Department of Dermatology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    BioDrugs 15:431-7. 2001
  9. ncbi request reprint The significance of multiple blue-grey dots (granularity) for the dermoscopic diagnosis of melanoma
    R P Braun
    Department of Dermatology, University Hospital Zurich, Gloriastr 31, 8032 Zurich, Switzerland
    Br J Dermatol 157:907-13. 2007
  10. ncbi request reprint Dermoscopy of pigmented lesions: a valuable tool in the diagnosis of melanoma
    R P Braun
    Department of Dermatology, University Hospital, Geneva, Switzerland
    Swiss Med Wkly 134:83-90. 2004

Collaborators

Detail Information

Publications35

  1. ncbi request reprint Identification of clonal T cells in the blood of patients with systemic sclerosis: positive correlation with response to photopheresis
    L E French
    Department of Dermatology, Geneva University Hospital, 24, Rue Micheli du Crest, CH 1211 Genève 14 Switzerland
    Arch Dermatol 137:1309-13. 2001
    ..To search for circulating clonal T-cell populations in patients with systemic sclerosis (SSc), and to determine whether T-cell clonality in the blood predicts therapeutic response to photopheresis...
  2. ncbi request reprint Modulation of clusterin gene expression in the rat mammary gland during pregnancy, lactation, and involution
    L E French
    Division of Dermatology, University Medical Center, Geneva, Switzerland
    Biol Reprod 55:1213-20. 1996
    ..This suggests that clusterin may be involved not only in mammary gland involution but also in the regulation of tubuloalveolar morphogenesis and alveolar epithelial cell differentiation in the adult rat mammary gland...
  3. ncbi request reprint Eccrine syringofibroadenoma in a patient with erosive palmoplantar lichen planus
    L E French
    Department of Dermatology, Geneva University Hospital, Switzerland
    Dermatology 195:399-401. 1997
    ..We suggest that these lesions are induced by the inflammatory remodelling associated with erosive lichen planus and propose to consider ESFA in the context of skin tissue remodelling as a new subtype of ESFA...
  4. ncbi request reprint Regression of multifocal, skin-restricted, CD30-positive large T-cell lymphoma with interferon alfa and bexarotene therapy
    L E French
    Department of Dermatology, University of Pennsylvania, Philadelphia, USA
    J Am Acad Dermatol 45:914-8. 2001
    ..This treatment was associated with rapid and marked regression of the patient's cutaneous lesions...
  5. ncbi request reprint Post-stripping sclerodermiform dermatitis
    L E French
    Department Hospitalo Universitaire Romand de Dermatologie Geneva Lausanne, Geneva, Switzerland
    Arch Dermatol 135:1387-91. 1999
    ....
  6. ncbi request reprint Incidence of transient acantholytic dermatosis (Grover's disease) in a hospital setting
    L E French
    Department of Dermatology DHURDV, HCU, Geneva, Switzerland
    Dermatology 198:410-1. 1999
    ..Grovers's disease may be triggered by bed rest...
  7. ncbi request reprint Selective expression of FLIP in malignant melanocytic skin lesions
    R R Bullani
    Department of Dermatology, Geneva University Medical School, Switzerland
    J Invest Dermatol 117:360-4. 2001
    ..Selective expression of FLIP by human melanomas may confer in vivo resistance to FasL and TRAIL, thus representing an additional mechanism by which melanoma cells escape immune destruction...
  8. ncbi request reprint Therapeutic advances in biological response modifiers in the treatment of cutaneous T-cell lymphoma
    C C Vittorio
    Department of Dermatology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    BioDrugs 15:431-7. 2001
    ..Future areas of research should assess not only survival and optimal treatment combinations, but also quality of life during the treatment period...
  9. ncbi request reprint The significance of multiple blue-grey dots (granularity) for the dermoscopic diagnosis of melanoma
    R P Braun
    Department of Dermatology, University Hospital Zurich, Gloriastr 31, 8032 Zurich, Switzerland
    Br J Dermatol 157:907-13. 2007
    ..The presence of multiple blue-grey dots (MBGD) is widely used by clinicians to decide if a pigmented lesion should be removed, but only little is known about their significance...
  10. ncbi request reprint Dermoscopy of pigmented lesions: a valuable tool in the diagnosis of melanoma
    R P Braun
    Department of Dermatology, University Hospital, Geneva, Switzerland
    Swiss Med Wkly 134:83-90. 2004
    ..It has been shown to increase diagnostic accuracy over clinical visual inspection in the hands of experienced physicians. This paper reviews the principles of dermoscopy, diagnostic strategies and recent technological developments...
  11. doi request reprint Topical treatment of cutaneous Kaposi sarcoma with imiquimod 5% in renal-transplant recipients: a clinicopathological observation
    B M Prinz Vavricka
    Department of Dermatology, University Hospital, Zurich, Switzerland
    Clin Exp Dermatol 37:620-5. 2012
    ..Thus, histological confirmation is crucial to confirm complete response...
  12. doi request reprint Mammalian target of rapamycin (mTOR) inhibitors slow skin carcinogenesis, but impair wound healing
    L Feldmeyer
    Department of Dermatology, University Hospital Zurich, Gloriastrasse 31, 8091 Zurich, Switzerland
    Br J Dermatol 166:422-4. 2012
    ..While randomized trials are running, organ transplant recipients are frequently switched from calcineurin inhibitors to mTOR inhibitors when cutaneous carcinogenesis increases...
  13. ncbi request reprint Intralesional and intravenous treatment of cutaneous B-cell lymphomas with the monoclonal anti-CD20 antibody rituximab: report and follow-up of eight cases
    K Kerl
    Department of Dermatology, Geneva University Medical School, 24 Rue Micheli du Crest, CH 1211 Geneva, Switzerland
    Br J Dermatol 155:1197-200. 2006
    ..The comparative efficacy of intravenous vs. intralesional rituximab in CBCL is not known...
  14. ncbi request reprint Cutaneous pseudolymphoma, lymphomatoid contact dermatitis type, as an unusual cause of symmetrical upper eyelid nodules
    R P Braun
    Department of Dermatology, Professorial Unit, University Hospital Geneva, 24, Rue Micheli du Crest, CH 1211 Geneva 14, Switzerland
    Br J Dermatol 143:411-4. 2000
    ..Complete regression of the lesions required treatment with systemic steroids and chlorambucil. No relapse occurred within a 5-year follow-up period...
  15. doi request reprint Diagnostic pitfall: pigmented lesion of the nipple--correlation between dermoscopy, reflectance confocal microscopy and histopathology
    I Kolm
    Department of Dermatology, University Hospital Zurich, Zurich, Switzerland
    Dermatology 222:1-4. 2011
    ..Finally, we focus on two main limitations of reflectance confocal microscopy: the misinterpretation of dendritic cells and the limitation of the imaging depth...
  16. ncbi request reprint Cutaneous peripheral T-cell lymphomas, unspecified/NOS and rare subtypes: a heterogeneous group of challenging cutaneous lymphomas
    W Kempf
    Department of Dermatology, University Hospital Zurich, Zurich, Switzerland
    G Ital Dermatol Venereol 147:553-62. 2012
    ..This review focuses on the clinicopathological aspects, the diagnostic criteria and the classification of the rare subtypes of PTL and PTL NOS...
  17. ncbi request reprint Post-surgical scalp wounds with exposed bone treated with a plant-derived wound therapeutic
    S Lauchli
    Department of Dermatology, University Hospital of Zurich, Zurich, Switzerland
    J Wound Care 21:228, 230, 232-3. 2012
    ..To evaluate the efficacy of a plant-derived wound dressing, a mixture of hypericum oil (Hypericum perforatum) and neem oil (Azadirachta indica), in scalp wounds with exposed bone...
  18. ncbi request reprint Extensive annular verrucous late secondary syphilis
    C C Pournaras
    Department of Dermatology, Geneva University Medical School, 24 Rue Micheli du Crest, 1211 Geneva 14, Switzerland
    Br J Dermatol 152:1343-5. 2005
    ..We present this case to illustrate a rare and potentially misleading clinical feature of late secondary syphilis, a disease considered to be of the past but still present in today's practice...
  19. ncbi request reprint Identification of amplified clonal T cell populations in the blood of patients with chronic graft-versus-host disease: positive correlation with response to photopheresis
    L E French
    Department of Dermatology, University of Pennsylvania, Philadelphia, PA, USA
    Bone Marrow Transplant 30:509-15. 2002
    ..001). Our findings suggest that patients with cGVHD that have detectable expanded clonal T cell populations in their peripheral blood, may be more likely to respond to treatment by photopheresis...
  20. doi request reprint Topical treatment habits in psoriasis patients receiving adalimumab
    A G A Kolios
    Department of Dermatology, University Hospital Zurich, Zurich, Switzerland
    Dermatology 224:228-30. 2012
    ..Here the topical treatment habits (corticosteroids and vitamin D derivates) and moisturizer use of 97 Swiss patients (male 65, female 32) receiving adalimumab have been evaluated...
  21. doi request reprint Changing pathology with changing drugs: skin cancer
    M B Karpova
    Department of Dermatology, University Hospital of Zurich, Switzerland
    Pathobiology 78:61-75. 2011
    ..For DFSP there is an opportunity already today to reduce the intensity of surgical procedures by pretreatment with targeted therapy. This article highlights important aspects in several skin cancer types...
  22. ncbi request reprint Periorbital oedema and erythema as a manifestation of discoid lupus erythematosus
    R P Braun
    Department of Dermatology, University Hospital, Geneva, Switzerland
    Dermatology 205:194-7. 2002
    ..Since swelling of the eyelid is common in the dermatological practice, dermatologists should be aware of the differential diagnosis and its occurrence in patients with DLE...
  23. ncbi request reprint Regression of extranodal natural killer/T-cell lymphoma, nasal type with denileukin diftitox (Ontak) and bexarotene (Targretin): report of a case
    K Kerl
    Department of Dermatology, Geneva University Medical School, 24 Rue Micheli du Crest, CH 1211 Geneva 14, Switzerland
    Br J Dermatol 154:988-91. 2006
    ..A striking, albeit transient, response occurred with this therapy. Combination treatment with denileukin diftitox and bexarotene should be further assessed in this aggressive type of cutaneous lymphoma...
  24. pmc Disfiguring annular sarcoidosis improved by adalimumab
    C A Kaiser
    Department of Dermatology, University Hospital of Zurich, Zurich, Switzerland
    Case Rep Dermatol 3:103-6. 2011
    ..5/10, and the Dermatology Life Quality Index from 16/30 to 3/30 points. In conclusion, TNF-α inhibition can control inflammation and disfigurement by cutaneous sarcoidosis and restore quality of life...
  25. doi request reprint Direct presentation of a melanocyte-associated antigen in peripheral lymph nodes induces cytotoxic CD8+ T cells
    Prisca Schuler
    Department of Dermatology, Louis Jeantet Laboratory, Skin Cancers, University Medical Center, Geneva, Switzerland
    Cancer Res 68:8410-8. 2008
    ..The peripheral priming by lymph node melanoblasts identified here may constitute an advantage for immunotherapies based on adoptive T-cell transfer...
  26. doi request reprint Reversal of UVA skin photosensitivity and DNA damage in kidney transplant recipients by replacing azathioprine
    G F L Hofbauer
    Department of Dermatology, University Hospital Zurich, Switzerland
    Am J Transplant 12:218-25. 2012
    ..Replacing azathioprine selectively reduced the skin photosensitivity to UVA, attenuated UVA-induced skin DNA damage, and is likely based on incorporated 6-TG in DNA...
  27. doi request reprint Evidence that venous hypertension causes stasis dermatitis
    K Sippel
    Department of Dermatology, University Hospital of Zurich, Zurich, Switzerland
    Phlebology 26:361-5. 2011
    ..Lower leg dermatitis healed in all 10 patients within 8-12 weeks and no recurrence was observed (1 year follow-up). These results support clinical experience that venous hypertension alone indeed can cause lower leg dermatitis...
  28. doi request reprint The mTOR inhibitor rapamycin significantly improves facial angiofibroma lesions in a patient with tuberous sclerosis
    G F L Hofbauer
    Department of Dermatology, University Hospital, Zurich, Switzerland
    Br J Dermatol 159:473-5. 2008
    ..Immunosuppressive treatment with rapamycin, a specific mTOR inhibitor, initiated because of renal transplantation, reduced facial angiofibroma dramatically...
  29. ncbi request reprint Frequent downregulation of Fas (CD95) expression and function in melanoma
    R R Bullani
    Department of Dermatology, Geneva University Medical School, 24 Rue Micheli du Crest, CH 1211 Geneva 14, Switzerland
    Melanoma Res 12:263-70. 2002
    ..Thus seven of the 13 melanoma cell lines were found to have impaired Fas signalling. Taken together, our results indicate that downregulation of Fas expression and resistance to Fas-mediated apoptosis are frequent in melanoma...
  30. pmc APRIL, a new ligand of the tumor necrosis factor family, stimulates tumor cell growth
    M Hahne
    Institute of Biochemistry, Lausanne Branch, University of Lausanne, Epalinges, Switzerland
    J Exp Med 188:1185-90. 1998
    ..Moreover, APRIL-transfected NIH-3T3 cells show an increased rate of tumor growth in nude mice compared with the parental cell line. These findings suggest that APRIL may be implicated in the regulation of tumor cell growth...
  31. ncbi request reprint T cell costimulation by the TNF ligand BAFF
    B Huard
    Department of Dermatology, Geneva University Medical Center, Geneva, Switzerland
    J Immunol 167:6225-31. 2001
    ..This highlights some differences in the BAFF signaling pathway in T and B cells. In conclusion, our results indicate that BAFF may play a role in the development of T cell responses, in addition to its role in B cell homeostasis...
  32. ncbi request reprint TRAMP, a novel apoptosis-mediating receptor with sequence homology to tumor necrosis factor receptor 1 and Fas(Apo-1/CD95)
    J L Bodmer
    Institute of Biochemistry, University of Lausanne, Switzerland
    Immunity 6:79-88. 1997
    ..TRAMP-induced cell death is inhibited by an inhibitor of ICE-like proteases, but not by Bcl-2. In addition, TRAMP does not appear to interact with any of the known apoptosis-inducing ligands of the TNF family...
  33. ncbi request reprint The TRAIL to selective tumor death
    L E French
    Nat Med 5:146-7. 1999
  34. ncbi request reprint Inhibition of death receptor signals by cellular FLIP
    M Irmler
    Institute of Biochemistry, Lausanne Branch, University of Lausanne, Switzerland
    Nature 388:190-5. 1997
    ..High levels of FLIP(L) protein are also detectable in melanoma cell lines and malignant melanoma tumours. Thus FLIP may be implicated in tissue homeostasis as an important regulator of apoptosis...
  35. ncbi request reprint Melanoma cell expression of Fas(Apo-1/CD95) ligand: implications for tumor immune escape
    M Hahne
    Institute of Biochemistry, University of Lausanne, CH 1066 Epalinges, Switzerland
    Science 274:1363-6. 1996
    ..In contrast, tumorigenesis was delayed in Fas-deficient lpr mutant mice in which immune effector cells cannot be killed by FasL. Thus, FasL may contribute to the immune privilege of tumors...