David J Fraser


Affiliation: University of Basel
Country: Switzerland


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    Fraser D, Podvinec M, Kaufmann M, Meyer U. Drugs mediate the transcriptional activation of the 5-aminolevulinic acid synthase (ALAS1) gene via the chicken xenobiotic-sensing nuclear receptor (CXR). J Biol Chem. 2002;277:34717-26 pubmed
    ..This is the first report describing direct transcriptional activation of ALAS1 by drugs via drug-responsive enhancer sequences. ..