Frank Enseleit

Summary

Affiliation: University Hospital
Country: Switzerland

Publications

  1. doi request reprint Effects of Pycnogenol on endothelial function in patients with stable coronary artery disease: a double-blind, randomized, placebo-controlled, cross-over study
    Frank Enseleit
    Cardiovascular Center Cardiology, University Hospital Zurich, Ramistrasse 100, Zurich, Switzerland
    Eur Heart J 33:1589-97. 2012
  2. doi request reprint Darusentan, a selective endothelin A receptor antagonist, for the oral treatment of resistant hypertension
    Frank Enseleit
    Cardiovascular Center Cardiology, University Hospital, Ramistrasse 100, 8091 Zurich, Switzerland
    Ther Adv Cardiovasc Dis 4:231-40. 2010
  3. doi request reprint Formation of pseudoaneurysm after aortic valve replacement without previous endocarditis: a case-control study
    Frank Enseleit
    Clinic of Cardiology, University Hospital Zurich, and Institute for Social and Preventive Medicine, University of Zurich, Zurich, Switzerland
    J Am Soc Echocardiogr 23:741-6. 2010
  4. ncbi request reprint Darusentan: a new perspective for treatment of resistant hypertension?
    Frank Enseleit
    University Hospital, Cardiovascular Center Cardiology, Ramistrasse 100, 8091 Zurich, Switzerland
    Expert Opin Investig Drugs 17:1255-63. 2008
  5. ncbi request reprint Continuous wave Doppler signal: a mystery
    Frank Enseleit
    Cardiovascular Center Cardiology, University Hospital Zurich, Zurich, Switzerland
    J Am Soc Echocardiogr 19:1191.e1-3. 2006
  6. doi request reprint Anti-VEGF therapies and blood pressure: more than meets the eye
    Frank Enseleit
    Cardiovascular Center Cardiology, University Hospital, Ramistrasse 100, Zurich, Switzerland
    Curr Hypertens Rep 12:33-8. 2010
  7. doi request reprint Acetaminophen increases blood pressure in patients with coronary artery disease
    Isabella Sudano
    Cardiovascular Center Cardiology University Hospital Zurich, Ramistrasse 100, CH 8091 Zurich, Switzerland
    Circulation 122:1789-96. 2010
  8. ncbi request reprint Cardiovascular effects of flavanol-rich chocolate in patients with heart failure
    Andreas J Flammer
    Cardiovascular Center, Cardiology University Hospital Zurich, Raemistrasse 100, Zurich, Switzerland
    Eur Heart J 33:2172-80. 2012
  9. doi request reprint Reconstituted HDL in acute coronary syndromes
    Remy Chenevard
    Cardiovascular Center, Cardiology, University Hospital, Zurich, Switzerland
    Cardiovasc Ther 30:e51-7. 2012
  10. doi request reprint Angiotensin-converting enzyme inhibition improves vascular function in rheumatoid arthritis
    Andreas J Flammer
    Cardiovascular Centre, Cardiology, University Hospital, Ramistrasse 100, 8091 Zurich, Switzerland
    Circulation 117:2262-9. 2008

Collaborators

Detail Information

Publications37

  1. doi request reprint Effects of Pycnogenol on endothelial function in patients with stable coronary artery disease: a double-blind, randomized, placebo-controlled, cross-over study
    Frank Enseleit
    Cardiovascular Center Cardiology, University Hospital Zurich, Ramistrasse 100, Zurich, Switzerland
    Eur Heart J 33:1589-97. 2012
    ..atlantica) that exerts antioxidative, anti-inflammatory, and anti-platelet effects. However, the effects of Pycnogenol on endothelial dysfunction, a precursor of atherosclerosis and cardiovascular events, remain still elusive...
  2. doi request reprint Darusentan, a selective endothelin A receptor antagonist, for the oral treatment of resistant hypertension
    Frank Enseleit
    Cardiovascular Center Cardiology, University Hospital, Ramistrasse 100, 8091 Zurich, Switzerland
    Ther Adv Cardiovasc Dis 4:231-40. 2010
    ....
  3. doi request reprint Formation of pseudoaneurysm after aortic valve replacement without previous endocarditis: a case-control study
    Frank Enseleit
    Clinic of Cardiology, University Hospital Zurich, and Institute for Social and Preventive Medicine, University of Zurich, Zurich, Switzerland
    J Am Soc Echocardiogr 23:741-6. 2010
    ..The aim of this study was to identify the predisposing factors for pseudoaneurysm formation after aortic valve replacement without previous endocarditis...
  4. ncbi request reprint Darusentan: a new perspective for treatment of resistant hypertension?
    Frank Enseleit
    University Hospital, Cardiovascular Center Cardiology, Ramistrasse 100, 8091 Zurich, Switzerland
    Expert Opin Investig Drugs 17:1255-63. 2008
    ..In conclusion, early clinical results from Phase II studies suggest that darusentan may find a place in the treatment of resistant hypertension...
  5. ncbi request reprint Continuous wave Doppler signal: a mystery
    Frank Enseleit
    Cardiovascular Center Cardiology, University Hospital Zurich, Zurich, Switzerland
    J Am Soc Echocardiogr 19:1191.e1-3. 2006
    ..However, the physical nature of the ultrasound beam may lead to unexpected findings in routine echocardiographic examination, which may lead to misdiagnosis and subsequent wrong clinical decisions...
  6. doi request reprint Anti-VEGF therapies and blood pressure: more than meets the eye
    Frank Enseleit
    Cardiovascular Center Cardiology, University Hospital, Ramistrasse 100, Zurich, Switzerland
    Curr Hypertens Rep 12:33-8. 2010
    ....
  7. doi request reprint Acetaminophen increases blood pressure in patients with coronary artery disease
    Isabella Sudano
    Cardiovascular Center Cardiology University Hospital Zurich, Ramistrasse 100, CH 8091 Zurich, Switzerland
    Circulation 122:1789-96. 2010
    ..Hence, the aim of this study was to evaluate the safety of acetaminophen in patients with coronary artery disease...
  8. ncbi request reprint Cardiovascular effects of flavanol-rich chocolate in patients with heart failure
    Andreas J Flammer
    Cardiovascular Center, Cardiology University Hospital Zurich, Raemistrasse 100, Zurich, Switzerland
    Eur Heart J 33:2172-80. 2012
    ..As statins are ineffective in CHF, alternative therapies are a clinical need. We therefore investigated whether FRC might improve cardiovascular function in patients with CHF...
  9. doi request reprint Reconstituted HDL in acute coronary syndromes
    Remy Chenevard
    Cardiovascular Center, Cardiology, University Hospital, Zurich, Switzerland
    Cardiovasc Ther 30:e51-7. 2012
    ....
  10. doi request reprint Angiotensin-converting enzyme inhibition improves vascular function in rheumatoid arthritis
    Andreas J Flammer
    Cardiovascular Centre, Cardiology, University Hospital, Ramistrasse 100, 8091 Zurich, Switzerland
    Circulation 117:2262-9. 2008
    ....
  11. doi request reprint Cholesterylestertransfer protein inhibition and endothelial function in type II hyperlipidemia
    Frank Hermann
    University Hospital Zurich, Zurich, Switzerland
    Thromb Res 123:460-5. 2009
    ....
  12. doi request reprint Cocoa, blood pressure, and vascular function
    Isabella Sudano
    Cardiovascular Center Cardiology, University Hospital Zurich, Raemistrasse 100, CH 8091, Zurich, Switzerland
    Curr Hypertens Rep 14:279-84. 2012
    ..It is the aim of this review to summarize the findings of cocoa and chocolate on blood pressure and vascular function...
  13. ncbi request reprint Selective COX-2 inhibition improves endothelial function in coronary artery disease
    Remy Chenevard
    Cardiovascular Center, Cardiology and Department of Rheumatology, University Hospital Zurich, Switzerland
    Circulation 107:405-9. 2003
    ....
  14. doi request reprint Haemodynamically irrelevant pericardial effusion is associated with increased mortality in patients with chronic heart failure
    Georg M Fröhlich
    Cardiovascular Center, Cardiology, University Hospital Zurich, Ramistrasse 100, Zurich CH 8091, Switzerland
    Eur Heart J 34:1414-23. 2013
    ..Pericardial effusion (PE) is a common finding in cardiac patients with chronic heart failure. The prognostic relevance of a small, haemodynamically non-compromising PE in such patients, however, remains to be determined...
  15. ncbi request reprint Hemodynamic and neurohumoral effects of selective endothelin A (ET(A)) receptor blockade in chronic heart failure: the Heart Failure ET(A) Receptor Blockade Trial (HEAT)
    Thomas F Luscher
    Cardiovascular Center, Cardiology, University Hospital, Zurich, Switzerland
    Circulation 106:2666-72. 2002
    ..We investigated hemodynamic and neurohumoral effects of 3 weeks of treatment with various dosages of the orally available ET(A) antagonist darusentan in addition to modern standard therapy in patients with CHF...
  16. doi request reprint Nonsteroidal antiinflammatory drugs, acetaminophen, and hypertension
    Isabella Sudano
    Cardiovascular Center Cardiology, University Hospital Zurich, Ramistrasse 100, 8091, Zurich, Switzerland
    Curr Hypertens Rep 14:304-9. 2012
    ..selective COX inhibitors are currently underway. This review summarizes the current knowledge on the cardiovascular effects of NSAIDs and acetaminophen, and their potential clinical consequences...
  17. doi request reprint Prophylactic implantable cardioverter defibrillator treatment in patients with end-stage heart failure awaiting heart transplantation
    Georg M Fröhlich
    Cardiovascular Division, University Hospital Zurich, Raemistrasse 100, Zurich CH 8091, Switzerland
    Heart 99:1158-65. 2013
    ..This study was designed to delineate the role of implantable cardioverter defibrillator (ICD) therapy for the primary and secondary prevention of sudden cardiac death in patients listed for heart transplantation...
  18. doi request reprint Takotsubo cardiomyopathy has a unique cardiac biomarker profile: NT-proBNP/myoglobin and NT-proBNP/troponin T ratios for the differential diagnosis of acute coronary syndromes and stress induced cardiomyopathy
    Georg M Fröhlich
    Cardiovascular Center Cardiology, University Hospital Zurich, Zurich, Switzerland
    Int J Cardiol 154:328-32. 2012
    ..It was our aim to identify TC by its unique cardiac biomarker profile at an early stage and, preferably, with non-invasive procedures only...
  19. ncbi request reprint Folic Acid improves baroreceptor sensitivity in hypertension
    Markus Bechir
    Cardiovascular Center, Cardiology, University Hospital, Zurich, Switzerland
    J Cardiovasc Pharmacol 45:44-8. 2005
    ..Thus, folic acid may represent a novel treatment for prevention of orthostatic dysregulation and/or arrhythmic complications resulting from baroreceptor dysfunction...
  20. ncbi request reprint Mental stress induces prolonged endothelial dysfunction via endothelin-A receptors
    Lukas E Spieker
    Cardiology, University Hospital, Zurich, Switzerland
    Circulation 105:2817-20. 2002
    ..6+/-1.2 versus 9.4+/-1.3%; NS). In contrast, intraarterial infusion of norepinephrine of similar duration as mental stress did not inhibit FMD...
  21. ncbi request reprint Effect of losartan on muscle sympathetic activity and baroreceptor function in systemic hypertension
    Markus Bechir
    Cardiovascular Center, Cardiology, University Hospital Zurich, Zurich, Switzerland
    Am J Cardiol 95:129-31. 2005
    ..007). This study for the first time demonstrates that in hypertensive patients, chronic AT(1) receptor antagonism inhibits muscle sympathetic nerve activity and that baroreceptor function is improved under these conditions...
  22. doi request reprint Surviving 20 years after heart transplantation: a success story
    Hector Rodriguez Cetina Biefer
    Clinic for Cardiovascular Surgery, University Hospital Zurich, Zurich, Switzerland
    Ann Thorac Surg 97:499-504. 2014
    ..We report the long-term outcomes of patients who survived 20 years or greater after heart transplantation...
  23. doi request reprint The impact of modern noninvasive cardiac imaging on coronary intervention rates
    Georg M Fröhlich
    Cardiovascular Center, Cardiology and Cardiac Imaging, Nuclear Medicine, University Hospital Zurich, Zurich, Switzerland The Heart Hospital London, University College London, London, United Kingdom
    J Interv Cardiol 27:50-7. 2014
    ....
  24. ncbi request reprint Anti-tumor necrosis factor-alpha treatment improves endothelial function in patients with rheumatoid arthritis
    David Hurlimann
    Cardiology Department, University Hospital, Zurich, Switzerland
    Circulation 106:2184-7. 2002
    ..Hence, the aim of the present study was to assess the effect of chronic antiinflammatory treatment with the anti-TNF-alpha antibody infliximab on disease activity and endothelial function in patients with active RA...
  25. doi request reprint Statins and the risk of cancer after heart transplantation
    Georg Marcus Fröhlich
    Cardiovascular Center Cardiology, Heart Failure Transplantation Clinic, University Hospital Zurich, Ramistrasse 100, CH 8091 Zurich, Switzerland
    Circulation 126:440-7. 2012
    ..Statins may have an impact on clinical outcomes beyond their lipid-lowering effects. The aim of the present study was to delineate whether statin therapy has an impact on cancer risk and total mortality after heart transplantation...
  26. doi request reprint Isolated cleft in the posterior mitral valve leaflet: a congenital form of mitral regurgitation
    Christophe A Wyss
    Clinic for Cardiology, University Hospital, 8091 Zurich, Switzerland
    Clin Cardiol 32:553-60. 2009
    ..Isolated congenital cleft of the posterior leaflet of the mitral valve is a rare cause of mitral regurgitation (MR). This study describes the clinical, echocardiographic, and intraoperative findings as well as treatment options...
  27. ncbi request reprint Donor-specific anti-HLA antibodies detected by Luminex: predictive for short-term but not long-term survival after heart transplantation
    Michelle Raess
    Division of Nephrology, University Hospital Zurich, Zurich, Switzerland
    Transpl Int 26:1097-107. 2013
    ..Thus, detection of DSA class I in pretransplant serum is a strong predictor of short-term, but not long-term survival and may help in the early management of heart transplant patients...
  28. ncbi request reprint Anti-inflammatory strategies in hypertension: focus on COX-1 and COX-2
    Matthias Hermann
    Cardiology, University Hospital Zurich, Ramistrasse 100, 8091 Zurich, Switzerland
    Curr Hypertens Rep 7:52-60. 2005
    ..In this review, we discuss the role of chronic low-grade inflammation in the context of cardiovascular disease with a focus on roles of cyclooxygenase-1 and -2 in potential anti-inflammatory treatment strategies...
  29. doi request reprint NT-proBNP provides incremental prognostic information in cardiac outpatients with and without echocardiographic findings
    Stefan Toggweiler
    Department of Cardiology, Cardiovascular Center, University Hospital Zurich, Zurich, Switzerland
    Clin Cardiol 34:183-8. 2011
    ..Outpatients frequently present with elevated natriuretic peptides in the absence of an obvious cardiac abnormality or with normal natriuretic peptides despite echocardiographic findings...
  30. doi request reprint Cyclosporine C0- versus C2-monitoring over three years in maintenance heart transplantation
    Matthias Hermann
    Cardiovascular Center Cardiology, University Hospital Zurich, Ramistrasse 100, 8091 Zurich, Switzerland
    Swiss Med Wkly 141:w13149. 2011
    ..In particular, data from long-term maintenance patients are not available...
  31. doi request reprint Systemic VEGF inhibition accelerates experimental atherosclerosis and disrupts endothelial homeostasis--implications for cardiovascular safety
    Stephan Winnik
    Division of Cardiology, University Hospital Zurich, Zurich, Switzerland Cardiovascular Research, Institute of Physiology, University of Zurich, Zurich, Switzerland
    Int J Cardiol 168:2453-61. 2013
    ..This study sought to examine the effects and underlying mechanisms of systemic VEGF inhibition in experimental atherosclerosis and aortic endothelial cells...
  32. ncbi request reprint Endothelin antagonists and heart failure
    David Hurlimann
    Cardio Vascular Center, Cardiology, University Hospital, CH 8091 Zurich, Switzerland
    Curr Hypertens Rep 4:85-92. 2002
    ..These results indicate that ET receptor antagonists indeed have a potential to improve hemodynamics, symptoms, and potentially prognosis in patients with CHF, which still carries a high mortality...
  33. ncbi request reprint Upgrading to resynchronization therapy after chronic right ventricular pacing improves left ventricular remodelling
    Georg Fröhlich
    Cardiovascular Center, Cardiology, University Hospital Zurich, Raemistrasse 100, Zurich CH 8091, Switzerland
    Eur Heart J 31:1477-85. 2010
    ..Upgrading patients with chronic RV pacing to cardiac resynchronization therapy (CRT) may be considered to restore synchronicity and prevent these deleterious effects...
  34. ncbi request reprint Detection of a novel exon 4 low-density lipoprotein receptor gene deletion in a swiss family with severe familial hypercholesterolemia
    Daniel Neff
    Institute of Clinical Chemistry, University Hospital, Zurich, Switzerland
    Clin Chem Lab Med 41:266-71. 2003
    ..Hence, we conclude that deletion of exon 4 in the LDLR gene drastically decreases low-density lipoprotein binding leading to severe hypercholesterolemia...
  35. ncbi request reprint Images in cardiovascular medicine. The blue man: amiodarone-induced skin discoloration
    Frank Enseleit
    Cardiovascular Center Cardiology, University Hospital Zurich, Zurich, Switzerland
    Circulation 113:e63. 2006
  36. ncbi request reprint Long-term continuous external electrocardiographic recording: a review
    Frank Enseleit
    Clinic of Cardiology, Cardiovascular Center, University Hospital Zurich, Ramistrasse 100, CH 8091 Zurich, Switzerland
    Europace 8:255-66. 2006
    ..Heart rate variability analysis has shown promise for predicting mortality rates in cardiac patients at high risk. We review recent advances in this field of non-invasive cardiac testing...
  37. ncbi request reprint A rare cause of complete heart block after transdermal botanical treatment for psoriasis
    Wojciech Wojtyna
    Kantonsspital Glarus, Department of Internal Medicine, Glarus, Switzerland
    Pacing Clin Electrophysiol 27:1686-8. 2004
    ..The pharmacological, epidemiological, and clinical features are discussed in brief...