Philippe A Eigenmann

Summary

Affiliation: University Hospital
Country: Switzerland

Publications

  1. pmc Research needs in allergy: an EAACI position paper, in collaboration with EFA
    Nikolaos G Papadopoulos
    Allergy Department, 2nd Pediatric Clinic, University of Athens, Athens, Greece
    Clin Transl Allergy 2:21. 2012
  2. doi request reprint Evidence of preventive effect of probiotics and prebiotics for infantile eczema
    Philippe A Eigenmann
    University Hospitals of Geneva and Medical School of the University of Geneva, Department of Child and Adolescent, Geneva, Switzerland
    Curr Opin Allergy Clin Immunol 13:426-31. 2013
  3. doi request reprint Testing children for allergies: why, how, who and when: an updated statement of the European Academy of Allergy and Clinical Immunology (EAACI) Section on Pediatrics and the EAACI-Clemens von Pirquet Foundation
    P A Eigenmann
    Department of Child and Adolescent, University Hospitals of Geneva, Geneva, Switzerland
    Pediatr Allergy Immunol 24:195-209. 2013
  4. pmc Exhaled nitric oxide decreases after positive food-allergen challenge
    Avigael H Benhamou
    Pediatric Allergy Unit, Geneva University Hospitals and University of Geneva, Geneva, Switzerland
    Clin Transl Allergy 1:14. 2011
  5. doi request reprint The ImmunoCAP Rapid Wheeze/Rhinitis Child test is useful in the initial allergy diagnosis of children with respiratory symptoms
    Philippe A Eigenmann
    Department of Paediatrics, Geneva University Hospitals, 1211 Geneva 14, Switzerland
    Pediatr Allergy Immunol 20:772-9. 2009
  6. ncbi request reprint Food colourings and preservatives--allergy and hyperactivity
    Philippe A Eigenmann
    Children s University Hospital, 1211 Geneva 14, Switzerland
    Lancet 364:823-4. 2004
  7. ncbi request reprint Continuing food-avoidance diets after negative food challenges
    Philippe A Eigenmann
    University Hospital of Geneva, Department of Paediatrics, Geneva, Switzerland
    Pediatr Allergy Immunol 17:601-5. 2006
  8. ncbi request reprint [Skin barrier defects in atopic dermatitis: new treatments?]
    P A Eigenmann
    Service d allergologie pédiatrique, Hopital des Enfants, HUG, Geneve
    Rev Med Suisse 7:2453-6. 2011
  9. ncbi request reprint The spectrum of cow's milk allergy
    Philippe A Eigenmann
    Department of Pediatrics, University Hospital of Geneva, Geneva, Switzerland
    Pediatr Allergy Immunol 18:265-71. 2007
  10. pmc Avirulant Salmonella typhimurium strains prevent food allergy in mice
    P A Eigenmann
    University Hospital of Geneva, Department of Paediatrics, Geneva, Switzerland
    Clin Exp Immunol 151:546-53. 2008

Detail Information

Publications44

  1. pmc Research needs in allergy: an EAACI position paper, in collaboration with EFA
    Nikolaos G Papadopoulos
    Allergy Department, 2nd Pediatric Clinic, University of Athens, Athens, Greece
    Clin Transl Allergy 2:21. 2012
    ..Active involvement of all stakeholders, including Patient Organizations and policy makers are necessary to achieve the aims emphasized herein...
  2. doi request reprint Evidence of preventive effect of probiotics and prebiotics for infantile eczema
    Philippe A Eigenmann
    University Hospitals of Geneva and Medical School of the University of Geneva, Department of Child and Adolescent, Geneva, Switzerland
    Curr Opin Allergy Clin Immunol 13:426-31. 2013
    ..Highlighting the most recent literature, we review here the most recent studies on probiotics and prebiotics and hypothesize on the most efficient intervention strategies...
  3. doi request reprint Testing children for allergies: why, how, who and when: an updated statement of the European Academy of Allergy and Clinical Immunology (EAACI) Section on Pediatrics and the EAACI-Clemens von Pirquet Foundation
    P A Eigenmann
    Department of Child and Adolescent, University Hospitals of Geneva, Geneva, Switzerland
    Pediatr Allergy Immunol 24:195-209. 2013
    ..We provide here evidence-based guidance on when and how to test for allergy in children based on common presenting symptoms suggestive of allergic diseases...
  4. pmc Exhaled nitric oxide decreases after positive food-allergen challenge
    Avigael H Benhamou
    Pediatric Allergy Unit, Geneva University Hospitals and University of Geneva, Geneva, Switzerland
    Clin Transl Allergy 1:14. 2011
    ..abstract:..
  5. doi request reprint The ImmunoCAP Rapid Wheeze/Rhinitis Child test is useful in the initial allergy diagnosis of children with respiratory symptoms
    Philippe A Eigenmann
    Department of Paediatrics, Geneva University Hospitals, 1211 Geneva 14, Switzerland
    Pediatr Allergy Immunol 20:772-9. 2009
    ..The ImmunoCAP Rapid test is an accurate test, in particular with regard to high specificity, for diagnosing allergy in children with recurrent respiratory diseases in primary care settings...
  6. ncbi request reprint Food colourings and preservatives--allergy and hyperactivity
    Philippe A Eigenmann
    Children s University Hospital, 1211 Geneva 14, Switzerland
    Lancet 364:823-4. 2004
  7. ncbi request reprint Continuing food-avoidance diets after negative food challenges
    Philippe A Eigenmann
    University Hospital of Geneva, Department of Paediatrics, Geneva, Switzerland
    Pediatr Allergy Immunol 17:601-5. 2006
    ..We suggest reassessing food consumption in all patients after a negative food challenge, and in those still avoiding the specific food to consider a repeated challenge test...
  8. ncbi request reprint [Skin barrier defects in atopic dermatitis: new treatments?]
    P A Eigenmann
    Service d allergologie pédiatrique, Hopital des Enfants, HUG, Geneve
    Rev Med Suisse 7:2453-6. 2011
    ..These agents could modify the pharmacological approach of AD treatments in the future...
  9. ncbi request reprint The spectrum of cow's milk allergy
    Philippe A Eigenmann
    Department of Pediatrics, University Hospital of Geneva, Geneva, Switzerland
    Pediatr Allergy Immunol 18:265-71. 2007
    ..The cases are discussed and summarized with more general recommendations for the clinical management of cow's milk allergy...
  10. pmc Avirulant Salmonella typhimurium strains prevent food allergy in mice
    P A Eigenmann
    University Hospital of Geneva, Department of Paediatrics, Geneva, Switzerland
    Clin Exp Immunol 151:546-53. 2008
    ..typhimurium AroA-pretreated mice had a similar immune response together with increased secretory IgA titres. Our experiments have proved a potential immunomodulatory protective effect by two avirulent S. typhimurium strains...
  11. ncbi request reprint Food colourings, preservatives, and hyperactivity
    Philippe A Eigenmann
    Children s University Hospital, 1211 Geneva, Switzerland
    Lancet 370:1524-5. 2007
  12. doi request reprint Diagnostic testing in the evaluation of food allergy
    Philippe A Eigenmann
    Pediatric Allergy Unit, Childrens Hospital, University Hospitals of Geneva, 6, rue Willy Donze, CH 1211 Geneva 14, Switzerland
    Pediatr Clin North Am 58:351-62, ix. 2011
    ..Of utmost importance is the need to correlate test results to the clinical picture. When a conclusion cannot be reached, oral food challenges should be performed for a definite diagnosis...
  13. doi request reprint New visions for food allergy: an iPAC summary and future trends
    Philippe A Eigenmann
    Department of Pediatrics, University Hospital of Geneva, Geneva, Switzerland
    Pediatr Allergy Immunol 19:26-39. 2008
    ....
  14. doi request reprint Mechanisms of food allergy
    Philippe A Eigenmann
    Department of Pediatrics, Geneva University Hospitals and University of Geneva, Geneva, Switzerland
    Pediatr Allergy Immunol 20:5-11. 2009
    ..These cases are discussed with regards to their specific immune events...
  15. ncbi request reprint T lymphocytes in food allergy: overview of an intricate network of circulating and organ-resident cells
    Philippe A Eigenmann
    Department of Pediatrics, and Division of Immunology and Allergy, University Hospital of Geneva, Geneva, Switzerland
    Pediatr Allergy Immunol 13:162-71. 2002
    ..Finally, potential T-cell directed therapeutic interventions (peptide-derived immunotherapy, DNA vaccination, or strategies preventing T cells from trafficking to target organs) are discussed...
  16. ncbi request reprint Antigen-specific secretory IgA antibodies in the gut are decreased in a mouse model of food allergy
    Christophe P Frossard
    Department of Pediatrics, University Hospital of Geneva, Switzerland
    J Allergy Clin Immunol 114:377-82. 2004
    ..A large body of evidence implicates IgA antibodies in the immune response to pathogens present in the gut. Whether IgA antibodies play a similar role in food allergy remains to be determined...
  17. ncbi request reprint Lymphocytes in Peyer patches regulate clinical tolerance in a murine model of food allergy
    Christophe P Frossard
    Department of Pediatrics, University Hospital of Geneva, 6 Rue Willy Donze, 1211 Geneva 14, Switzerland
    J Allergy Clin Immunol 113:958-64. 2004
    ..Food allergy can lead to severe, potentially life-threatening anaphylactic reactions. To generate efficient strategies aimed at an active cure, a better understanding of the pathogenic mechanisms is strongly needed...
  18. doi request reprint Predicting positive food challenges in children sensitised to peanuts/tree nuts
    Sian Ludman
    Division of Allergology, Immunology and Rheumatology, Department of Pediatrics, University Hospital, Lausanne, Switzerland
    Pediatr Allergy Immunol 24:276-81. 2013
    ..Children with atopic diseases in early life are frequently found with positive IgE tests to peanuts/tree nuts without a history of previous ingestion. We aimed to identify risk factors for reactions to nuts at first introduction...
  19. ncbi request reprint Oral administration of an IL-10-secreting Lactococcus lactis strain prevents food-induced IgE sensitization
    Christophe P Frossard
    University Hospital of Geneva, Department of Pediatrics, Geneva, Switzerland
    J Allergy Clin Immunol 119:952-9. 2007
    ..Because tolerance to food is potentially modulated by IL-10, strategies to prevent food allergy should favor an increased delivery of IL-10 to the gut...
  20. doi request reprint Allergic triggers in atopic dermatitis
    Jean Christoph Caubet
    University Hospitals of Geneva, Geneva, Switzerland
    Immunol Allergy Clin North Am 30:289-307. 2010
    ..In a subset of patients, therapeutic measures, such as elimination of the incriminated allergen(s), can lead to marked improvement of AD; this is especially true for food allergens, but can also apply to inhalant allergens...
  21. doi request reprint Correlation between specific immunoglobulin E levels and the severity of reactions in egg allergic patients
    Avigael H Benhamou
    University Hospital of Geneva, Department of Paediatrics, Geneva, Switzerland
    Pediatr Allergy Immunol 19:173-9. 2008
    ..18 and 11.00 (median 3.70) (p = 0.006). Our results show a correlation between IgE titres and the severity of the clinical reaction to egg. IgE titres may help to determine the potential risk of a reaction to eggs...
  22. doi request reprint Evaluation of food allergy in patients with atopic dermatitis
    Marcel M Bergmann
    Pediatric Allergy Unit, Department of Pediatrics, University Hospitals of Geneva, Geneva, Switzerland
    J Allergy Clin Immunol Pract 1:22-8. 2013
    ..Follow-up clinical evaluation with a detailed history and tracking of the level of specific IgE to implicated foods are typically used to evaluate the development of clinical tolerance, further confirmed by an oral food challenge. ..
  23. ncbi request reprint Do we have suitable in-vitro diagnostic tests for the diagnosis of food allergy?
    Philippe A Eigenmann
    Pediatric Allergy, Department of Pediatrics, University Hospital of Geneva, Geneva, Switzerland
    Curr Opin Allergy Clin Immunol 4:211-3. 2004
    ..Skin prick testing and in-vitro diagnosis is helpful in most cases and can help to avoid cumbersome food challenges. This review considers recent progress in the use of in-vitro tests in the diagnosis of food allergy...
  24. ncbi request reprint The role of IL-10 in preventing food-induced anaphylaxis
    Christophe P Frossard
    Department of Paediatrics, University Hospital of Geneva, 6 Rue Willy Donze, 1211 Geneva 14, Switzerland
    Expert Opin Biol Ther 8:1309-17. 2008
    ..Food allergy is a common condition resulting in a much impaired quality of life. So far, no clearly effective preventive and therapeutic strategies have been established. However, several options have been tested with promising results...
  25. doi request reprint Managing possible antibiotic allergy in children
    Jean Christoph Caubet
    Department of Child and Adolescent, University Hospitals of Geneva, Medical School of the University of Geneva, Geneva, Switzerland
    Curr Opin Infect Dis 25:279-85. 2012
    ..Highlighting the most recent literature, the present review addresses the management of children with a possible antibiotic allergy...
  26. ncbi request reprint The T lymphocyte in food-allergy disorders
    Philippe A Eigenmann
    Department of Pediatrics, University Hospital of Geneva, Geneva, Switzerland
    Curr Opin Allergy Clin Immunol 3:199-203. 2003
    ....
  27. doi request reprint An overview of cow's milk allergy in children
    Avigael H Benhamou
    Department of Pediatrics, Geneva University Hospital, Geneva, Switzerland
    Swiss Med Wkly 139:300-7. 2009
    ..The overall natural evolution of the disease is favourable with most patients achieving tolerance to milk by the age of five years, but some patients will remain allergic for life...
  28. ncbi request reprint [Atopic dermatitis and food allergies]
    A H Benhamou
    Departement de Pediatrie, HUG, 1211 Geneve 14
    Rev Med Suisse 3:1038-43. 2007
    ..Skin prick tests, in vitro tests and food challenges can identify a concomitant allergy, leading to specific allergen avoidance mea-sures potentially improving skin symptoms...
  29. ncbi request reprint [Allergic reactions and vaccines: distinguishing true and false reactions]
    J C Caubet
    Département de l enfant et de l adolescent, HUG, 1211 Geneve 14
    Rev Med Suisse 5:416-9. 2009
    ..Before this diagnosis can accurately be made, a complete work up is essential. If an allergy workup is necessary, it will be primarily based on skin tests...
  30. ncbi request reprint Diagnosis of IgE-mediated food allergy among Swiss children with atopic dermatitis
    P A Eigenmann
    Department of Pediatrics, University of Geneva School of Medicine, Switzerland
    Pediatr Allergy Immunol 11:95-100. 2000
    ..Together with milk and eggs, peanuts were most frequently involved in allergic reactions...
  31. ncbi request reprint Anaphylaxis to cow's milk and beef meat proteins
    Philippe A Eigenmann
    Department of Pediatrics, University of Geneva School of Medicine, Geneva, Switzerland
    Ann Allergy Asthma Immunol 89:61-4. 2002
    ..This report summarizes a review of anaphylactic reactions to cow's milk and beef presented at a recent conference on adverse reactions to bovine proteins...
  32. doi request reprint Parent perceived quality of life is age-dependent in children with food allergy
    Jacqueline Wassenberg
    Division of Allergology, Immunology and Rhumatology, Department of Paediatrics, University Hospital Center and University of Lausanne, Lausanne, Switzerland
    Pediatr Allergy Immunol 23:412-9. 2012
    ..Food allergy in children significantly affects their quality of life. Its impact can be analyzed by quality of life questionnaires...
  33. doi request reprint Diagnostic issues in pediatric drug allergy
    Jean Christoph Caubet
    University Hospitals of Geneva and Medical School of the University of Geneva, Department of Child and Adolescent, Geneva, Switzerland
    Curr Opin Allergy Clin Immunol 12:341-7. 2012
    ..The present review addresses the most recent literature regarding the diagnosis of allergy for the most commonly implicated drugs in children, that is, antibiotics, nonsteroidal anti-inflammatory drugs (NSAID) and vaccines...
  34. doi request reprint The role of penicillin in benign skin rashes in childhood: a prospective study based on drug rechallenge
    Jean Christoph Caubet
    Department of Child and Adolescent, University Hospitals of Geneva and Medical School of the University of Geneva, Geneva, Switzerland
    J Allergy Clin Immunol 127:218-22. 2011
    ..Delayed-onset urticarial or maculopapular rashes are frequently observed in children treated with β-lactams. Many are labeled "allergic" without reliable testing...
  35. ncbi request reprint Diagnosis of allergy syndromes: do symptoms always mean allergy?
    P A Eigenmann
    Department of Pediatrics, University Hospital of Geneva, Geneva, Switzerland
    Allergy 60:6-9. 2005
    ..Cooperation between all healthcare professionals involved in the treatment of allergy patients is also a key to improve our response to the allergy epidemic...
  36. doi request reprint Educational case series: Mechanisms of drug allergy
    Jean Christoph Caubet
    Department of Child and Adolescent, University Hospitals of Geneva and Medical School of the University of Geneva, Geneva, Switzerland
    Pediatr Allergy Immunol 22:559-67. 2011
    ..These cases are correlated to the immune mechanism potentially involved...
  37. ncbi request reprint An internet-based survey on the circumstances of food-induced reactions following the diagnosis of IgE-mediated food allergy
    P A Eigenmann
    Department of Pediatrics, University Hospital of Geneva, 24 Rue Micheli du Crest, 1211 Geneva 14, Switzerland
    Allergy 57:449-53. 2002
    ..Despite careful avoidance measures, food allergic patients have a significant risk of anaphylactic episodes. Risk situations need to be identified for more efficient preventive measures...
  38. ncbi request reprint Oral carrageenan induces antigen-dependent oral tolerance: prevention of anaphylaxis and induction of lymphocyte anergy in a murine model of food allergy
    C P Frossard
    Department of Pediatrics, Division of Immunology and Allergy, University Hospital of Geneva, Switzerland
    Pediatr Res 49:417-22. 2001
    ..In conclusion, carrageenan administered to young mice in conjunction with low doses of allergen before sensitization efficiently prevents anaphylaxis...
  39. ncbi request reprint Breast-feeding and atopic eczema dermatitis syndrome: protective or harmful?
    P A Eigenmann
    Department of Pediatrics, University Hospital of Geneva, Switzerland
    Allergy 59:42-4. 2004
    ..The aim of this review is not to analyse systematically the current literature, but to suggest a scientifically and clinically based analysis of the benefits of breast-feeding in atopic infants...
  40. ncbi request reprint Antihistamine and sodium cromoglycate medication for food cold water exercise-induced anaphylaxis
    A H Benhamou
    Department of Pediatrics, University Hospital of Geneva, 6 Rue Willy Donze, 1211 Geneva 14, Switzerland
    Allergy 62:1471-2. 2007
  41. ncbi request reprint Future therapeutic options in food allergy
    P A Eigenmann
    Department of Pediatrics, University Hospital of Geneva, Geneva, Switzerland
    Allergy 58:1217-23. 2003
    ..Rapidly evolving findings might provide hope for a cure of food allergy in the near future...
  42. ncbi request reprint An Internet-based survey of anaphylactic reactions to foods
    P A Eigenmann
    Department of Pediatrics, Division of Immunology and Allergy, Geneva, Switzerland
    Allergy 56:540-3. 2001
    ..The conventional management of anaphylaxis might still be improved...
  43. doi request reprint Dietary prevention of allergic diseases in infants and small children
    Arne Høst
    Department of Pediatrics, Odense University Hospital, Odense, Denmark
    Pediatr Allergy Immunol 19:1-4. 2008
    ....
  44. doi request reprint Early identification of atopy in the prediction of persistent asthma in children
    Peter D Sly
    Telethon Institute for Child Health Research, Centre for Child Health Research, University of Western Australia, Perth, WA, Australia
    Lancet 372:1100-6. 2008
    ..Identification of an asthmatic child's atopic status in early life has practical clinical and prognostic implications, and sets the basis for future preventative strategies...