Louis Du Pasquier

Summary

Affiliation: University of Basel
Country: Switzerland

Publications

  1. ncbi A human TAPBP (TAPASIN)-related gene, TAPBP-R
    Michelle S Teng
    Immunology Division, Department of Pathology, Cambridge, GB
    Eur J Immunol 32:1059-68. 2002
  2. doi The Dscam homologue of the crustacean Daphnia is diversified by alternative splicing like in insects
    Daniela Brites
    Zoologisches Institut, Evolutionsbiologie, Universitat Basel, Vesalgasse 1, Switzerland
    Mol Biol Evol 25:1429-39. 2008
  3. pmc Fish 'n' TRIMs
    Louis Du Pasquier
    University of Basel, Institute of Zoology and Evolutionary Biology, Vesalgasse 1, Basel CH 4051, Switzerland
    J Biol 8:50. 2009
  4. ncbi Duplication and MHC linkage of the CTX family of genes in Xenopus and in mammals
    L Du Pasquier
    Basel Institute for Immunology, Switzerland
    Eur J Immunol 29:1729-39. 1999
  5. ncbi Immunology. Insects diversify one molecule to serve two systems
    Louis Du Pasquier
    Institute of Zoology and Evolutionary Biology, University of Basel, Vesalgasse 1, CH 4051 Basel, Switzerland
    Science 309:1826-7. 2005
  6. ncbi Germline and somatic diversification of immune recognition elements in Metazoa
    Louis Du Pasquier
    University of Basel, Institute of Zoology and Evolutionary Biology, Vesalgassel, CH 4051 Basel, Switzerland
    Immunol Lett 104:2-17. 2006
  7. ncbi Innate immunity in early chordates and the appearance of adaptive immunity
    Louis Du Pasquier
    Institute of Zoology, University of Basel, Rheinsprung 9, CH 4051 Basel, Switzerland
    C R Biol 327:591-601. 2004
  8. ncbi Immunoglobulin superfamily receptors in protochordates: before RAG time
    Louis Du Pasquier
    Institute of Zoology, University of Basel, Basel, Switzerland
    Immunol Rev 198:233-48. 2004
  9. ncbi Speculations on the origin of the vertebrate immune system
    Louis Du Pasquier
    Institute of Zoology, University of Basel, Rheinsprung 9, CH 4051 Basel, Switzerland
    Immunol Lett 92:3-9. 2004
  10. ncbi The fate of duplicated immunity genes in the dodecaploid Xenopus ruwenzoriensis
    Louis Du Pasquier
    University of Basel, Department of Zoology and Evolutionary Biology University of Basel Vesalgasse 1 CH 4051 Basel Switzerland
    Front Biosci (Landmark Ed) 14:177-91. 2009

Collaborators

Detail Information

Publications29

  1. ncbi A human TAPBP (TAPASIN)-related gene, TAPBP-R
    Michelle S Teng
    Immunology Division, Department of Pathology, Cambridge, GB
    Eur J Immunol 32:1059-68. 2002
    ..TAPASIN-R lacks an obvious ER retention signal. The function of TAPASIN-R will be of interest in regards to the evolution of the immune system as well as antigen processing...
  2. doi The Dscam homologue of the crustacean Daphnia is diversified by alternative splicing like in insects
    Daniela Brites
    Zoologisches Institut, Evolutionsbiologie, Universitat Basel, Vesalgasse 1, Switzerland
    Mol Biol Evol 25:1429-39. 2008
    ..The genealogy of the Dscam gene family from vertebrates and invertebrates confirmed that the highly diversified form of the gene evolved from a nondiversified form before the split of insects and crustaceans...
  3. pmc Fish 'n' TRIMs
    Louis Du Pasquier
    University of Basel, Institute of Zoology and Evolutionary Biology, Vesalgasse 1, Basel CH 4051, Switzerland
    J Biol 8:50. 2009
    ..The history of these receptors involves ancient linkage to paralogs of the major histocompatibility complex, and the family has invertebrate precursors...
  4. ncbi Duplication and MHC linkage of the CTX family of genes in Xenopus and in mammals
    L Du Pasquier
    Basel Institute for Immunology, Switzerland
    Eur J Immunol 29:1729-39. 1999
    ..Some human CTX homologies are on chromosomes 11 and 21, but others are on chromosomes 1, 6 and 19, which contain MHC paralogous regions; this suggests that a very ancient linkage group has been preserved...
  5. ncbi Immunology. Insects diversify one molecule to serve two systems
    Louis Du Pasquier
    Institute of Zoology and Evolutionary Biology, University of Basel, Vesalgasse 1, CH 4051 Basel, Switzerland
    Science 309:1826-7. 2005
  6. ncbi Germline and somatic diversification of immune recognition elements in Metazoa
    Louis Du Pasquier
    University of Basel, Institute of Zoology and Evolutionary Biology, Vesalgassel, CH 4051 Basel, Switzerland
    Immunol Lett 104:2-17. 2006
    ..Metazoa had to adapt to the conditions generated by this diversity: the control of expression of multiple genes and the risk of autoimmunity...
  7. ncbi Innate immunity in early chordates and the appearance of adaptive immunity
    Louis Du Pasquier
    Institute of Zoology, University of Basel, Rheinsprung 9, CH 4051 Basel, Switzerland
    C R Biol 327:591-601. 2004
    ..In this way the adaptive immune system could have developed from a set of receptors involved in a primitive local innate immunity involving NF-kappaB-mediated apoptosis...
  8. ncbi Immunoglobulin superfamily receptors in protochordates: before RAG time
    Louis Du Pasquier
    Institute of Zoology, University of Basel, Basel, Switzerland
    Immunol Rev 198:233-48. 2004
    ....
  9. ncbi Speculations on the origin of the vertebrate immune system
    Louis Du Pasquier
    Institute of Zoology, University of Basel, Rheinsprung 9, CH 4051 Basel, Switzerland
    Immunol Lett 92:3-9. 2004
    ..The role of virus receptor for many of these clustered genes products provides perhaps one way of envisaging the recruitment of this family in the adaptive immune system from an ancient form of innate antiviral immunity...
  10. ncbi The fate of duplicated immunity genes in the dodecaploid Xenopus ruwenzoriensis
    Louis Du Pasquier
    University of Basel, Department of Zoology and Evolutionary Biology University of Basel Vesalgasse 1 CH 4051 Basel Switzerland
    Front Biosci (Landmark Ed) 14:177-91. 2009
    ..laevis versus 4 in X. ruwenzoriensis. One interpretation is that natural selection acts more on the number of genes than on the mode of inheritance (polysomic versus disomic)...
  11. ncbi Workshop report: evolutionary immunobiology--new approaches, new paradigms
    Louis Du Pasquier
    Department of Zoology, University of Basel, Rheinsprung 9, CH 4051 Basel, Switzerland
    Dev Comp Immunol 27:263-71. 2003
  12. doi [Metazoa immune receptors diversification during evolution]
    Louis Du Pasquier
    Université de Bâle, Institut de Zoologie et de Biologie évolutive, Vesalgasse 1, CH 4051 Basel, Switzerland
    Med Sci (Paris) 25:273-80. 2009
    ..At all levels many convergences reveal even better than conservations the intensity of pressure exerted on the immune systems to diversify their immunoreceptors in front of the changing environment...
  13. ncbi B-cell development in the amphibian Xenopus
    L Du Pasquier
    Basel Institute for Immunology, Switzerland
    Immunol Rev 175:201-13. 2000
    ..Switch from IgM to other isotypes is mediated by loop-excision deletion of the IgM constant region gene via switch regions which, unlike their mammalian counterpart, are A-T rich and reveal conserved microsites for the breakpoints...
  14. ncbi Meeting the demand for innate and adaptive immunities during evolution
    L Du Pasquier
    University of Basel, Institute of Zoology, Basel, Switzerland
    Scand J Immunol 62:39-48. 2005
    ....
  15. ncbi The fate of duplicated major histocompatibility complex class Ia genes in a dodecaploid amphibian, Xenopus ruwenzoriensis
    Benedicte Sammut
    Basel Institute for Immunology, Switzerland
    Eur J Immunol 32:2698-709. 2002
    ..This is a rare situation among vertebrates. The observed polymorphism is most likely due to the interlocus genetic exchanges related to the peculiar mode of speciation of the genus...
  16. pmc Population genetics of duplicated alternatively spliced exons of the Dscam gene in Daphnia and Drosophila
    Daniela Brites
    Zoologisches Institut, Evolutionsbiologie, University of Basel, Basel, Switzerland
    PLoS ONE 6:e27947. 2011
    ....
  17. doi Cloning of the unculturable parasite Pasteuria ramosa and its Daphnia host reveals extreme genotype-genotype interactions
    Pepijn Luijckx
    Institut of Zoology, Evolutionsbiologie, University of Basel, Basel, Switzerland
    Ecol Lett 14:125-31. 2011
    ..We recommend caution when using P. ramosa isolates as the presence of multiple genotypes may influence the outcome and interpretation of some experiments...
  18. ncbi The fate of duplicated major histocompatibility complex class Ia genes in a dodecaploid amphibian, Xenopus ruwenzoriensis
    Benedicte Sammut
    Basel Institute for Immunology, Basel, Switzerland
    Eur J Immunol 32:1593-604. 2002
    ..This is a rare situation among vertebrates. The observed polymorphism is most likely due to the interlocus genetic exchanges related to the peculiar mode of speciation of the genus...
  19. ncbi Evolution of innate and adaptive immunity: can we draw a line?
    Martin F Flajnik
    Department of Microbiology and Immunology, University of Maryland at Baltimore School of Medicine, Baltimore, MD 21201 1559, USA
    Trends Immunol 25:640-4. 2004
    ..Although we draw no startling conclusions, we hope to encourage different thought patterns when viewing immune systems...
  20. ncbi Endothelial adhesion molecule ESAM binds directly to the multidomain adaptor MAGI-1 and recruits it to cell contacts
    Frank Wegmann
    Institute of Cell Biology, ZMBE, University of Muenster, 48149 Muenster, Germany
    Exp Cell Res 300:121-33. 2004
    ..In CHO cells, recruitment of MAGI-1 to cell contacts required the presence of ESAM. Hence, ESAM may be involved in anchoring MAGI-1 at endothelial tight junctions...
  21. pmc A novel family of diversified immunoregulatory receptors in teleosts is homologous to both mammalian Fc receptors and molecules encoded within the leukocyte receptor complex
    James L Stafford
    Department of Microbiology, University of Mississippi Medical Center, Jackson, MS 39216 4505, USA
    Immunogenetics 58:758-73. 2006
    ....
  22. ncbi Genomic analysis of immunity in a Urochordate and the emergence of the vertebrate immune system: "waiting for Godot"
    Kaoru Azumi
    Department of Biochemistry, Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan
    Immunogenetics 55:570-81. 2003
    ..However, there are key V regions, the essential feature of an immunoglobulin superfamily VC1-like core, and possible proto-MHC regions scattered throughout the genome waiting for Godot...
  23. ncbi An evolutionarily conserved target motif for immunoglobulin class-switch recombination
    Ali A Zarrin
    Howard Hughes Medical Institute, The Children s Hospital, CBR Institute for Biomedical Research, and Department of Genetics, Harvard University Medical School, Boston, Massachusetts 02115, USA
    Nat Immunol 5:1275-81. 2004
    ..We propose that AGCT is a primordial CSR motif that targets AID through a non-R-loop mechanism involving an AID-replication protein A complex...
  24. doi Immunoreceptor tyrosine-based inhibition motifs: a quest in the past and future
    Marc Daëron
    Institut Pasteur, Departement d Immunologie, Unité d Allergologie Moléculaire et Cellulaire, Paris, France
    Immunol Rev 224:11-43. 2008
    ....
  25. ncbi ciCD94-1, an ascidian multipurpose C-type lectin-like receptor expressed in Ciona intestinalis hemocytes and larval neural structures
    Ivana Zucchetti
    Laboratory of Cell Biology, Stazione Zoologica Anton Dohrn Villa Comunale, 80121 Naples, Italy
    Differentiation 76:267-82. 2008
    ..These findings suggest that ciCD94-1 has different roles in immunity and in development, thus strengthening the concept of gene co-option during evolution and of an evolutionary relationship between the nervous and the immune systems...
  26. pmc The chicken leukocyte receptor complex encodes a primordial, activating, high-affinity IgY Fc receptor
    Birgit C Viertlboeck
    Institute for Animal Physiology, University of Munich, 80539 Munich, Germany
    Proc Natl Acad Sci U S A 104:11718-23. 2007
    ..CHIR-AB1 thus represents a primordial Fc receptor that combines features of different mammalian counterparts...
  27. ncbi Channel catfish leukocyte immune-type receptors contain a putative MHC class I binding site
    James L Stafford
    Department of Microbiology, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS, 39216 4505, USA
    Immunogenetics 59:77-91. 2007
    ..Taken together, these results suggest that fish LITRs have an orthologous relationship to LRC-encoded receptors such as the human LILRs and could potentially function as a diverse family of MHC class I-binding receptors...
  28. ncbi Costimulatory receptors in jawed vertebrates: conserved CD28, odd CTLA4 and multiple BTLAs
    David Bernard
    Institut National de la Recherche Agronomique, Unite de Virologie et Immunologie Moleculaires, 78352 Jouy en Josas Cedex, France
    Dev Comp Immunol 31:255-71. 2007
    ..The genomic localization of these genes in vertebrate genomes supports the split between the BTLA and CD28 families...
  29. ncbi The chicken leukocyte receptor complex: a highly diverse multigene family encoding at least six structurally distinct receptor types
    Birgit C Viertlboeck
    Institute for Animal Physiology, University of Munich, Munich, Germany
    J Immunol 175:385-93. 2005
    ..Fluorescence in situ hybridization localized the CHIR gene cluster to microchromosome 31 and identified this region as orthologous to the human leukocyte receptor complex...