Research Topics
Genomes and Genes | Jean Luc DreyerSummaryAffiliation: University of Fribourg Country: Switzerland Publications
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Detail Information
Publications
The brain-specific Neural Zinc Finger transcription factor 2b (NZF-2b/7ZFMyt1) causes suppression of cocaine-induced locomotor activityVijay Chandrasekar
Division of Biochemistry, Department of Medicine, University of Fribourg, Rue du Musee 5, CH 1700 Fribourg, Switzerland
Neurobiol Dis 37:86-98. 2010..These changes lead to decreased responsiveness of the animal to the locomotor-activating effects of cocaine, indicating that NZF-2b/7ZFMyt1 expression plays an important role in phenotypic changes induced by the drug...
New insights into the roles of microRNAs in drug addiction and neuroplasticityJean Luc Dreyer
Division of Biochemistry, Department of Medicine, University of Fribourg, Rue du Musee 5, CH 1700 Fribourg, Switzerland
Genome Med 2:92. 2010..In this review, the aim is to provide an overview of the emerging role of miRNAs in addiction...
Lentiviral vector-mediated gene transfer and RNA silencing technology in neuronal dysfunctionsJean Luc Dreyer
Division of Biochemistry, Department of Medicine, University of Fribourg, Rue du Musee 5, 1700 Fribourg, Switzerland
Mol Biotechnol 47:169-87. 2011..Recently, lentivirus gene transfer has been an invaluable tool for evaluation of gene function in behavioral disorders such as drug addiction and attention-deficit hyperactivity disorder or in learning and cognition...
Lentiviral vector-mediated gene transfer and RNA silencing technology in neuronal dysfunctionsJean Luc Dreyer
Division of Biochemistry, Department of Medicine, University of Fribourg, Fribourg, Switzerland
Methods Mol Biol 614:3-35. 2010..Recently, lentivirus gene transfer has been an invaluable tool for evaluation of gene function in behavioral disorders such as drug addiction and attention-deficit hyperactivity disorder or in learning and cognition...
Silencing dopamine D3-receptors in the nucleus accumbens shell in vivo induces changes in cocaine-induced hyperlocomotionAmine Bahi
Institute of Biochemistry, University of Fribourg, Rue du Musee 5, CH 1700 Fribourg, Switzerland
Eur J Neurosci 21:3415-26. 2005..Thus D(3)R expression significantly contributes to behavioural changes associated with chronic cocaine delivery...
Alpha-synuclein in the nucleus accumbens induces changes in cocaine behaviour in ratsFrederic Boyer
Institute of Biochemistry, University of Fribourg, Rue du Musee 5, CH 1700 Fribourg, Switzerland
Eur J Neurosci 26:2764-76. 2007..This suggests that targeting alpha-synuclein function could provide new therapeutic strategies to treat cocaine abuse, for which there is no available treatment...
Regulation of MiR-124, Let-7d, and MiR-181a in the accumbens affects the expression, extinction, and reinstatement of cocaine-induced conditioned place preferenceVijay Chandrasekar
Division of Biochemistry, Department of Medicine, University of Fribourg, Fribourg, Switzerland
Neuropsychopharmacology 36:1149-64. 2011..Our results describe a complex regulatory pathway mediated by miRNAs in cocaine-mediated neuronal adaptations...
microRNAs miR-124, let-7d and miR-181a regulate cocaine-induced plasticityVijay Chandrasekar
Division of Biochemistry, Department of Medicine, University of Fribourg, Rue du Musee 5, Chemin du Musee 5, CH 1700 Fribourg, Switzerland
Mol Cell Neurosci 42:350-62. 2009....
Effects of urokinase-type plasminogen activator in the acquisition, expression and reinstatement of cocaine-induced conditioned-place preferenceAmine Bahi
Division of Biochemistry, Department of Medicine, University of Fribourg, Chemin du Musee 5, CH 1700 Fribourg, Switzerland
Behav Brain Res 191:17-25. 2008....
A decrease in gamma-synuclein expression within the nucleus accumbens increases cocaine intravenous self-administration in the ratFrederic Boyer
Institute of Biochemistry, University of Fribourg, Switzerland
Addict Biol 16:120-3. 2011..This effect was associated with an increase in cocaine-induced reinstatement. The present data reveal that GSyn exert a specific negative control on cocaine-induced reinforcing and incentive effects...
The role of gamma-synuclein in cocaine-induced behaviour in ratsFrederic Boyer
Institute of Biochemistry, University of Fribourg, Rue du Musee 5, CH 1700 Fribourg, Switzerland
Eur J Neurosci 27:2938-51. 2008....
The Brain-Specific Neural Zinc Finger Transcription Factor 2b (NZF-2b/7ZFMyt1) Suppresses Cocaine Self-Administration in RatsVijay Chandrasekar
Division of Biochemistry, Department of Medicine, University of Fribourg Fribourg, Switzerland
Front Behav Neurosci 4:14. 2010....
The role of tissue-type plasminogen activator system in amphetamine-induced conditional place preference extinction and reinstatementAmine Bahi
Department of Medicine, University of Fribourg, Fribourg, Switzerland
Neuropsychopharmacology 33:2726-34. 2008..Together, these data clearly indicate that tPA plays an important role in acquisition of amphetamine-induced CPP, but its role in CPP expression does not seem important...
