Jean Luc Dreyer

Summary

Affiliation: University of Fribourg
Country: Switzerland

Publications

  1. doi request reprint The brain-specific Neural Zinc Finger transcription factor 2b (NZF-2b/7ZFMyt1) causes suppression of cocaine-induced locomotor activity
    Vijay Chandrasekar
    Division of Biochemistry, Department of Medicine, University of Fribourg, Rue du Musee 5, CH 1700 Fribourg, Switzerland
    Neurobiol Dis 37:86-98. 2010
  2. pmc The Brain-Specific Neural Zinc Finger Transcription Factor 2b (NZF-2b/7ZFMyt1) Suppresses Cocaine Self-Administration in Rats
    Vijay Chandrasekar
    Division of Biochemistry, Department of Medicine, University of Fribourg Fribourg, Switzerland
    Front Behav Neurosci 4:14. 2010
  3. doi request reprint Lentiviral vector-mediated gene transfer and RNA silencing technology in neuronal dysfunctions
    Jean Luc Dreyer
    Division of Biochemistry, Department of Medicine, University of Fribourg, Fribourg, Switzerland
    Methods Mol Biol 614:3-35. 2010
  4. doi request reprint Lentiviral vector-mediated gene transfer and RNA silencing technology in neuronal dysfunctions
    Jean Luc Dreyer
    Division of Biochemistry, Department of Medicine, University of Fribourg, Rue du Musee 5, 1700 Fribourg, Switzerland
    Mol Biotechnol 47:169-87. 2011
  5. pmc New insights into the roles of microRNAs in drug addiction and neuroplasticity
    Jean Luc Dreyer
    Division of Biochemistry, Department of Medicine, University of Fribourg, Rue du Musee 5, CH 1700 Fribourg, Switzerland
    Genome Med 2:92. 2010
  6. ncbi request reprint In vivo gene silencing of CD81 by lentiviral expression of small interference RNAs suppresses cocaine-induced behaviour
    Amine Bahi
    Institute of Biochemistry, University of Fribourg, Fribourg, Switzerland
    J Neurochem 92:1243-55. 2005
  7. ncbi request reprint CD81-induced behavioural changes during chronic cocaine administration: in vivo gene delivery with regulatable lentivirus
    Amine Bahi
    Institute of Biochemistry, University of Fribourg, Rue du Musee 5, CH 1700 Fribourg, Switzerland
    Eur J Neurosci 19:1621-33. 2004
  8. ncbi request reprint Silencing dopamine D3-receptors in the nucleus accumbens shell in vivo induces changes in cocaine-induced hyperlocomotion
    Amine Bahi
    Institute of Biochemistry, University of Fribourg, Rue du Musee 5, CH 1700 Fribourg, Switzerland
    Eur J Neurosci 21:3415-26. 2005
  9. ncbi request reprint Silencing urokinase in the ventral tegmental area in vivo induces changes in cocaine-induced hyperlocomotion
    Amine Bahi
    Institute of Biochemistry, University of Fribourg, Fribourg, Switzerland
    J Neurochem 98:1619-31. 2006
  10. ncbi request reprint Cocaine-induced expression changes of axon guidance molecules in the adult rat brain
    Amine Bahi
    Institute of Biochemistry, University of Fribourg, Chemin du Musee 5, CH 1700 Fribourg, Switzerland
    Mol Cell Neurosci 28:275-91. 2005

Collaborators

  • Amine Bahi
  • Tal Kafri
  • Vijay Chandrasekar
  • Frederic Boyer
  • VĂ©ronique Deroche-Gamonet
  • Eric Balado
  • Pier V Piazza

Detail Information

Publications18

  1. doi request reprint The brain-specific Neural Zinc Finger transcription factor 2b (NZF-2b/7ZFMyt1) causes suppression of cocaine-induced locomotor activity
    Vijay Chandrasekar
    Division of Biochemistry, Department of Medicine, University of Fribourg, Rue du Musee 5, CH 1700 Fribourg, Switzerland
    Neurobiol Dis 37:86-98. 2010
    ..These changes lead to decreased responsiveness of the animal to the locomotor-activating effects of cocaine, indicating that NZF-2b/7ZFMyt1 expression plays an important role in phenotypic changes induced by the drug...
  2. pmc The Brain-Specific Neural Zinc Finger Transcription Factor 2b (NZF-2b/7ZFMyt1) Suppresses Cocaine Self-Administration in Rats
    Vijay Chandrasekar
    Division of Biochemistry, Department of Medicine, University of Fribourg Fribourg, Switzerland
    Front Behav Neurosci 4:14. 2010
    ....
  3. doi request reprint Lentiviral vector-mediated gene transfer and RNA silencing technology in neuronal dysfunctions
    Jean Luc Dreyer
    Division of Biochemistry, Department of Medicine, University of Fribourg, Fribourg, Switzerland
    Methods Mol Biol 614:3-35. 2010
    ..Recently, lentivirus gene transfer has been an invaluable tool for evaluation of gene function in behavioral disorders such as drug addiction and attention-deficit hyperactivity disorder or in learning and cognition...
  4. doi request reprint Lentiviral vector-mediated gene transfer and RNA silencing technology in neuronal dysfunctions
    Jean Luc Dreyer
    Division of Biochemistry, Department of Medicine, University of Fribourg, Rue du Musee 5, 1700 Fribourg, Switzerland
    Mol Biotechnol 47:169-87. 2011
    ..Recently, lentivirus gene transfer has been an invaluable tool for evaluation of gene function in behavioral disorders such as drug addiction and attention-deficit hyperactivity disorder or in learning and cognition...
  5. pmc New insights into the roles of microRNAs in drug addiction and neuroplasticity
    Jean Luc Dreyer
    Division of Biochemistry, Department of Medicine, University of Fribourg, Rue du Musee 5, CH 1700 Fribourg, Switzerland
    Genome Med 2:92. 2010
    ..In this review, the aim is to provide an overview of the emerging role of miRNAs in addiction...
  6. ncbi request reprint In vivo gene silencing of CD81 by lentiviral expression of small interference RNAs suppresses cocaine-induced behaviour
    Amine Bahi
    Institute of Biochemistry, University of Fribourg, Fribourg, Switzerland
    J Neurochem 92:1243-55. 2005
    ..Furthermore, silencing endogenous CD81 in vivo resulted in a significant decrease in locomotor activity over controls, again suppressing cocaine-induced behaviour...
  7. ncbi request reprint CD81-induced behavioural changes during chronic cocaine administration: in vivo gene delivery with regulatable lentivirus
    Amine Bahi
    Institute of Biochemistry, University of Fribourg, Rue du Musee 5, CH 1700 Fribourg, Switzerland
    Eur J Neurosci 19:1621-33. 2004
    ..This study provides a powerful approach for evaluating a gene function in vivo in a single animal under various paradigms, even on gene candidates, which display small changes of expression...
  8. ncbi request reprint Silencing dopamine D3-receptors in the nucleus accumbens shell in vivo induces changes in cocaine-induced hyperlocomotion
    Amine Bahi
    Institute of Biochemistry, University of Fribourg, Rue du Musee 5, CH 1700 Fribourg, Switzerland
    Eur J Neurosci 21:3415-26. 2005
    ..Thus D(3)R expression significantly contributes to behavioural changes associated with chronic cocaine delivery...
  9. ncbi request reprint Silencing urokinase in the ventral tegmental area in vivo induces changes in cocaine-induced hyperlocomotion
    Amine Bahi
    Institute of Biochemistry, University of Fribourg, Fribourg, Switzerland
    J Neurochem 98:1619-31. 2006
    ..These data strongly support the major role of urokinase in cocaine-mediated plasticity changes...
  10. ncbi request reprint Cocaine-induced expression changes of axon guidance molecules in the adult rat brain
    Amine Bahi
    Institute of Biochemistry, University of Fribourg, Chemin du Musee 5, CH 1700 Fribourg, Switzerland
    Mol Cell Neurosci 28:275-91. 2005
    ..We conclude that in some brain regions, exposure to psychomotor-stimulant drugs produce expression changes in axon guidance molecules, which may contribute to cognitive deficits associated with drug abuse...
  11. ncbi request reprint In vivo gene delivery of urokinase-type plasminogen activator with regulatable lentivirus induces behavioural changes in chronic cocaine administration
    Amine Bahi
    Institute of Biochemistry, University of Fribourg, Rue du Musee 5, CH 1700 Fribourg, Switzerland
    Eur J Neurosci 20:3473-88. 2004
    ..These behavioural effects were completely abolished when the active site of the protease was point-mutated and used as a dominant negative. The physiological relevance of these drastic behavioural changes is discussed...
  12. ncbi request reprint Alpha-synuclein in the nucleus accumbens induces changes in cocaine behaviour in rats
    Frederic Boyer
    Institute of Biochemistry, University of Fribourg, Rue du Musee 5, CH 1700 Fribourg, Switzerland
    Eur J Neurosci 26:2764-76. 2007
    ..This suggests that targeting alpha-synuclein function could provide new therapeutic strategies to treat cocaine abuse, for which there is no available treatment...
  13. pmc Regulation of MiR-124, Let-7d, and MiR-181a in the accumbens affects the expression, extinction, and reinstatement of cocaine-induced conditioned place preference
    Vijay Chandrasekar
    Division of Biochemistry, Department of Medicine, University of Fribourg, Fribourg, Switzerland
    Neuropsychopharmacology 36:1149-64. 2011
    ..Our results describe a complex regulatory pathway mediated by miRNAs in cocaine-mediated neuronal adaptations...
  14. doi request reprint microRNAs miR-124, let-7d and miR-181a regulate cocaine-induced plasticity
    Vijay Chandrasekar
    Division of Biochemistry, Department of Medicine, University of Fribourg, Rue du Musee 5, Chemin du Musee 5, CH 1700 Fribourg, Switzerland
    Mol Cell Neurosci 42:350-62. 2009
    ....
  15. doi request reprint A decrease in gamma-synuclein expression within the nucleus accumbens increases cocaine intravenous self-administration in the rat
    Frederic Boyer
    Institute of Biochemistry, University of Fribourg, Switzerland
    Addict Biol 16:120-3. 2011
    ..This effect was associated with an increase in cocaine-induced reinstatement. The present data reveal that GSyn exert a specific negative control on cocaine-induced reinforcing and incentive effects...
  16. doi request reprint Effects of urokinase-type plasminogen activator in the acquisition, expression and reinstatement of cocaine-induced conditioned-place preference
    Amine Bahi
    Division of Biochemistry, Department of Medicine, University of Fribourg, Chemin du Musee 5, CH 1700 Fribourg, Switzerland
    Behav Brain Res 191:17-25. 2008
    ....
  17. doi request reprint The role of gamma-synuclein in cocaine-induced behaviour in rats
    Frederic Boyer
    Institute of Biochemistry, University of Fribourg, Rue du Musee 5, CH 1700 Fribourg, Switzerland
    Eur J Neurosci 27:2938-51. 2008
    ....
  18. doi request reprint The role of tissue-type plasminogen activator system in amphetamine-induced conditional place preference extinction and reinstatement
    Amine Bahi
    Department of Medicine, University of Fribourg, Fribourg, Switzerland
    Neuropsychopharmacology 33:2726-34. 2008
    ..Together, these data clearly indicate that tPA plays an important role in acquisition of amphetamine-induced CPP, but its role in CPP expression does not seem important...