V Dietz

Summary

Affiliation: University of Zurich
Country: Switzerland

Publications

  1. ncbi Contribution of feedback and feedforward strategies to locomotor adaptations
    Tania Lam
    Spinal Cord Injury Center, Balgrist University Hospital, Zurich, Switzerland
    J Neurophysiol 95:766-73. 2006
  2. ncbi Neurological aspects of spinal-cord repair: promises and challenges
    Volker Dietz
    Spinal Cord Injury Centre, University Hospital Balgrist, Zurich, Switzerland
    Lancet Neurol 5:688-94. 2006
  3. ncbi Locomotor activity in spinal cord-injured persons
    V Dietz
    Spinal Chord Injury Center, University Hospital Balgrist, 8008 Zurich, Switzerland
    J Appl Physiol (1985) 96:1954-60. 2004
  4. ncbi [Basic principles and therapy of spasticity]
    V Dietz
    ParaCare, Universitätsklinik Balgrist, Zurich
    Ther Umsch 57:684-9. 2000
  5. ncbi Degradation of neuronal function following a spinal cord injury: mechanisms and countermeasures
    Volker Dietz
    Spinal Cord Injury Center, Balgrist University Hospital, Forchstrasse 340, 8008 Zurich, Switzerland
    Brain 127:2221-31. 2004
  6. ncbi Spinal cord pattern generators for locomotion
    V Dietz
    ParaCare, Institute for Research and Rehabilitation, University Hospital Balgrist, Forchstr 340, 8008 Zurich, Switzerland
    Clin Neurophysiol 114:1379-89. 2003
  7. ncbi Recovery from spinal cord injury--underlying mechanisms and efficacy of rehabilitation
    V Dietz
    ParaCare, Swiss Paraplegic Centre of the University Hospital Bagrlist, Zurich, Switzerland
    Acta Neurochir Suppl 89:95-100. 2004
  8. pmc Spinal cord lesion: effects of and perspectives for treatment
    V Dietz
    ParaCare, Paraplegic Centre, University Hospital Balgrist, Zurich, Switzerland
    Neural Plast 8:83-90. 2001
  9. ncbi Neuronal coordination of arm and leg movements during human locomotion
    V Dietz
    ParaCare, Paraplegic Centre University Hospital Balgrist, Forchstrasse 340, Ch 8008 Zurich, Switzerland
    Eur J Neurosci 14:1906-14. 2001
  10. ncbi Locomotor activity in spinal man: significance of afferent input from joint and load receptors
    Volker Dietz
    Paraplegic Centre of the University Hospital Balgrist, Zurich, Switzerland
    Brain 125:2626-34. 2002

Detail Information

Publications104 found, 100 shown here

  1. ncbi Contribution of feedback and feedforward strategies to locomotor adaptations
    Tania Lam
    Spinal Cord Injury Center, Balgrist University Hospital, Zurich, Switzerland
    J Neurophysiol 95:766-73. 2006
    ..In summary, adaptive changes in the walking pattern were driven by both feedback and feedforward adjustments in the walking pattern appropriate for overcoming the effects of resistance...
  2. ncbi Neurological aspects of spinal-cord repair: promises and challenges
    Volker Dietz
    Spinal Cord Injury Centre, University Hospital Balgrist, Zurich, Switzerland
    Lancet Neurol 5:688-94. 2006
    ..The relevance of this degradation for a regeneration-inducing treatment needs to be investigated. Fifth, the prerequisites to enable appropriate reconnection of regenerating tract fibres in a postacute stage have still to be established...
  3. ncbi Locomotor activity in spinal cord-injured persons
    V Dietz
    Spinal Chord Injury Center, University Hospital Balgrist, 8008 Zurich, Switzerland
    J Appl Physiol (1985) 96:1954-60. 2004
    ..In the future, if regeneration approaches can successfully be applied in human SCI, even individuals with complete SCI may recover walking ability with locomotor training...
  4. ncbi [Basic principles and therapy of spasticity]
    V Dietz
    ParaCare, Universitätsklinik Balgrist, Zurich
    Ther Umsch 57:684-9. 2000
    ..Exaggerated reflexes do only little contribute to the movement disorder...
  5. ncbi Degradation of neuronal function following a spinal cord injury: mechanisms and countermeasures
    Volker Dietz
    Spinal Cord Injury Center, Balgrist University Hospital, Forchstrasse 340, 8008 Zurich, Switzerland
    Brain 127:2221-31. 2004
    ..This might be achieved by a continuous training approach starting early after injury...
  6. ncbi Spinal cord pattern generators for locomotion
    V Dietz
    ParaCare, Institute for Research and Rehabilitation, University Hospital Balgrist, Forchstr 340, 8008 Zurich, Switzerland
    Clin Neurophysiol 114:1379-89. 2003
    ..The significance of this research is in a better understanding of the pathophysiology underlying movement disorders and the consequences for an appropriate treatment...
  7. ncbi Recovery from spinal cord injury--underlying mechanisms and efficacy of rehabilitation
    V Dietz
    ParaCare, Swiss Paraplegic Centre of the University Hospital Bagrlist, Zurich, Switzerland
    Acta Neurochir Suppl 89:95-100. 2004
    ..This suggests that neuronal circuits underlying 'locomotor pattern generation' in man is not restricted to any specific level of the spinal cord, but extends from thoraco-lumbal to cervical levels...
  8. pmc Spinal cord lesion: effects of and perspectives for treatment
    V Dietz
    ParaCare, Paraplegic Centre, University Hospital Balgrist, Zurich, Switzerland
    Neural Plast 8:83-90. 2001
    ..The pathophysiology and functional significance of spastic muscle tone and the effects of treadmill training on the locomotor pattern underlying new attempts to improve the mobility of patients with paraplegia are reviewed...
  9. ncbi Neuronal coordination of arm and leg movements during human locomotion
    V Dietz
    ParaCare, Paraplegic Centre University Hospital Balgrist, Forchstrasse 340, Ch 8008 Zurich, Switzerland
    Eur J Neurosci 14:1906-14. 2001
    ..The results are compatible with the assumption that the proximal arm muscle responses are associated with the swinging of the arms during gait, as a residual function of quadrupedal locomotion...
  10. ncbi Locomotor activity in spinal man: significance of afferent input from joint and load receptors
    Volker Dietz
    Paraplegic Centre of the University Hospital Balgrist, Zurich, Switzerland
    Brain 125:2626-34. 2002
    ..This is in line with observations from infant stepping experiments and experiments in cats. Afferent feedback from knee and ankle joints may be involved largely in the control of focal movements...
  11. ncbi Proprioception and locomotor disorders
    Volker Dietz
    ParaCare, Institute for Rehabilitation and Research, University Hospital Balgrist, Forchstrasse 340, CH 8008, Zurich, Switzerland
    Nat Rev Neurosci 3:781-90. 2002
  12. ncbi Do human bipeds use quadrupedal coordination?
    Volker Dietz
    ParaCare, Institute for Rehabilitation and Research, University Hospital Balgrist, Forchstrasse 340, 8008 Zurich, Switzerland
    Trends Neurosci 25:462-7. 2002
    ..The persistence of such movement control has consequences for rehabilitation and the applicability of animal research to human patients with spinal cord injury...
  13. ncbi Significance of load receptor input during locomotion: a review
    V Dietz
    Swiss Paraplegic Centre, University Hospital Balgrist, Forchstr 340, CH 8008, Zurich, Switzerland
    Gait Posture 11:102-10. 2000
    ..Recent experiments in paraplegic patients show that the beneficial effects of a locomotor training critically depends on the initial degree of body unloading and reloading during the course of the training period...
  14. ncbi [Focus on current research: improving the mobility of paraplegic patients]
    V Dietz
    Schweizerisches Paraplegikerzentrum, Universitätsklinik Balgrist, Zurich
    Schweiz Med Wochenschr 130:829-36. 2000
    ..Improvement of training of the spinal cord locomotor centre can be expected from triggering of spinal cord reflexes and regeneration of spinal tract fibres, which is expected to be possible in the near future...
  15. ncbi Locomotion in patients with spinal cord injuries
    V Dietz
    Swiss Paraplegic Centre, University Hospital Balgrist, Zurich, Switzerland
    Phys Ther 77:508-16. 1997
    ..This article reviews the pathophysiology and functional importance of increased muscle tone and the effects of treadmill training on the locomotor pattern underlying new attempts to improve the mobility of patients with paraplegia...
  16. ncbi Neurophysiology of gait disorders: present and future applications
    V Dietz
    Swiss Paraplegic Centre, University Hospital Balgrist, Zurich, Switzerland
    Electroencephalogr Clin Neurophysiol 103:333-55. 1997
    ..In the future, the knowledge gained from gait analysis may help in the selection of the appropriate pharmacological and physical treatment required even though the patient may only be at an early stage of motor impairment...
  17. ncbi Leg muscle activation during gait in Parkinson's disease: influence of body unloading
    V Dietz
    Paraplegic Centre, University Hospital Balgrist, Zurich, Switzerland
    Electroencephalogr Clin Neurophysiol 105:400-5. 1997
    ..It is suggested that the latter observation is due to a change in the threshold or bias of the extensor load reflex mechanism in the patients. The slope or gain of this reflex appears to be preserved...
  18. pmc Effects of changing stance conditions on anticipatory postural adjustment and reaction time to voluntary arm movement in humans
    V Dietz
    ParaCare, Paraplegic Centre of the University Hospital Balgrist, Forchstrasse 340, Ch 8008 Zurich, Switzerland
    J Physiol 524:617-27. 2000
    ....
  19. ncbi Level of spinal cord lesion determines locomotor activity in spinal man
    V Dietz
    Swiss Paraplegic Centre, University Hospital Balgrist, Forchstr 340, Ch 8008 Zurich, Switzerland
    Exp Brain Res 128:405-9. 1999
    ....
  20. ncbi Locomotor capacity and recovery of spinal cord function in paraplegic patients: a clinical and electrophysiological evaluation
    V Dietz
    Swiss Paraplegic Centre, University Hospital Balgrist, Zurich, Switzerland
    Electroencephalogr Clin Neurophysiol 109:140-53. 1998
    ..The findings of this study may be relevant for future clinical treatment of paraplegic patients...
  21. ncbi Single joint perturbation during gait: neuronal control of movement trajectory
    V Dietz
    Spinal Cord Injury Center, Balgrist University Hospital, Forchstrasse 340, Ch 8008 Zurich, Switzerland
    Exp Brain Res 158:308-16. 2004
    ..This was interpreted as being directed to stabilise body equilibrium...
  22. doi Vertical perturbations of human gait: organisation and adaptation of leg muscle responses
    V Bachmann
    Spinal Cord Injury Center, University Hospital Balgrist, Forchstrasse 340, 8008, Zurich, Switzerland
    Exp Brain Res 186:123-30. 2008
    ..This is assumed to be due to the required compensation of the perturbations by polysynaptic spinal reflexes released following the perturbations. The findings underline the importance of load receptor input for the control of locomotion...
  23. doi Locomotion in Parkinson's disease: neuronal coupling of upper and lower limbs
    V Dietz
    Spinal Cord Injury Center, Balgrist University Hospital, Zurich, Switzerland
    Brain 131:3421-31. 2008
    ..In the tibialis anterior the SR is attenuated presumably because of a stronger voluntary (i.e. cortical) control of leg movements...
  24. doi Modulation of spinal reflex by assisted locomotion in humans with chronic complete spinal cord injury
    M Bolliger
    Balgrist University Hospital, Zurich, Switzerland
    Clin Neurophysiol 121:2152-8. 2010
    ..Here we report on the modulation of SR by assisted locomotion in healthy and chronic motor cSCI subjects...
  25. ncbi Treadmill training in incomplete spinal cord injured rats
    K Fouad
    Brain Research Institute, University and ETH Zurich, Winterthurerstrasse 190, 8057, Zurich, Switzerland
    Behav Brain Res 115:107-13. 2000
    ..It is probable that the spared ventral and ventro-lateral fibers allowed spontaneous recovery and 'self-training' to occur to such an extend that systematic treadmill training did not provide additional improvement...
  26. ncbi Neuronal function in chronic spinal cord injury: divergence between locomotor and flexion- and H-reflex activity
    R Muller
    Spinal Cord Injury Center, Balgrist University Hospital, Forchstrasse 340, 8008 Zurich, Switzerland
    Clin Neurophysiol 117:1499-507. 2006
    ..The objective of this study was to examine the behavior of locomotor EMG activity and of spinal reflexes in patients with chronic motor-complete SCI...
  27. ncbi Limits of locomotor ability in subjects with a spinal cord injury
    H J A van Hedel
    1Spinal Cord Injury Center, Balgrist University Hospital, Zurich, Switzerland
    Spinal Cord 43:593-603. 2005
    ..Case-control study with pair-wise matching...
  28. doi Obstacle stepping in children: task acquisition and performance
    J Michel
    Spinal Cord Injury Center, Balgrist University Hospital Zurich, Zurich, Switzerland
    Gait Posture 31:341-6. 2010
    ..Finally, ZNA tests can improve the prediction of complex adaptive locomotor behaviour compared to calendar age alone...
  29. doi Modulation of spinal neuronal excitability by spinal direct currents and locomotion after spinal cord injury
    M Hubli
    Spinal Cord Injury Center, Balgrist University Hospital, University of Zurich, Zurich, Switzerland
    Clin Neurophysiol 124:1187-95. 2013
    ..We applied transcutaneous spinal direct current stimulation (tsDCS) and locomotor activity, to determine whether the excitability of spinal neuronal circuitries underlying locomotion can be modulated after motor complete SCI...
  30. doi Changes in spinal reflex and locomotor activity after a complete spinal cord injury: a common mechanism?
    V Dietz
    Spinal Cord Injury Centre, University Hospital Balgrist, Forchstrasse 340, 8008 Zurich, Switzerland
    Brain 132:2196-205. 2009
    ..These findings should be taken into consideration in the development of novel rehabilitation schemes and programs to facilitate regeneration-inducing therapies in spinal cord injury subjects...
  31. doi Body weight supported gait training: from laboratory to clinical setting
    V Dietz
    University Hospital Balgrist, Spinal Cord Injury Center, Forchstr 340, Ch 8008 Zurich, Switzerland
    Brain Res Bull 76:459-63. 2008
    ..Presently, individuals with complete SCI, spinal neuronal circuits undergo a degradation of their function 1 year after injury...
  32. doi Influence of spinal reflexes on the locomotor pattern after spinal cord injury
    M Hubli
    Spinal Cord Injury Centre, University Hospital Balgrist, Zurich, Switzerland
    Gait Posture 34:409-14. 2011
    ..It is proposed that the two SR components have different physiological roles during locomotion...
  33. ncbi Modulation of locomotor activity in complete spinal cord injury
    L Lunenburger
    Spinal Cord Injury Center, Balgrist University Hospital, Zurich, Switzerland
    Exp Brain Res 174:638-46. 2006
    ..The application of various speeds might enhance the effect of locomotor training in incomplete SCI subjects...
  34. ncbi Facilitation of spinal reflexes assists performing but not learning an obstacle-avoidance locomotor task
    J Michel
    Spinal Cord Injury Center, Balgrist University Hospital, Forchstrasse 340, Ch 8008 Zurich, Switzerland
    Eur J Neurosci 26:1299-306. 2007
    ..This facilitation might provide assistance in safe obstacle stepping, e.g. to compensate quickly if resistance is encountered...
  35. doi Obstacle stepping involves spinal anticipatory activity associated with quadrupedal limb coordination
    J Michel
    Spinal Cord Injury Center, Balgrist University Hospital, Forchstrasse 340, Ch 8008 Zurich, Switzerland
    Eur J Neurosci 27:1867-75. 2008
    ..This is presumably achieved by an up-regulated activity of coupled cervico-thoracal interneuronal circuits...
  36. pmc Obstacle avoidance during human walking: learning rate and cross-modal transfer
    T Erni
    ParaCare, Paraplegic Centre of the University Hospital Balgrist, Zurich, Switzerland
    J Physiol 534:303-12. 2001
    ..The fact that little CMT occurs from visual to non-visual stimuli and from ACU to LED suggests that visual afferent input is processed in a different way to non-visual stimuli...
  37. doi Outcome after incomplete spinal cord injury: central cord versus Brown-Sequard syndrome
    M Wirz
    Spinal Cord Injury Center, Balgrist University Hospital, Zurich, Switzerland
    Spinal Cord 48:407-14. 2010
    ..A retrospective analysis of prospectively collected data...
  38. ncbi The effects of unilateral pyramidal tract section on hindlimb motor performance in the rat
    G A Metz
    Brain Research Institute, University and Swiss Federal Institute of Technology, Zurich, Switzerland
    Behav Brain Res 96:37-46. 1998
    ..We conclude that the possibility to correlate regenerative changes following selective pyramidal tract lesions with hindlimb function is thus limited...
  39. ncbi Efficient testing of motor function in spinal cord injured rats
    G A Metz
    Brain Research Institute, University and ETH Zurich, 8057, Zurich, Switzerland
    Brain Res 883:165-77. 2000
    ..This approach should help to standardize modular testing procedures across different laboratories working on spinal cord injury...
  40. pmc Effects of body immersion on postural adjustments to voluntary arm movements in humans: role of load receptor input
    V Dietz
    Paraplegic Centre, University Hospital Balgrist, Zurich, Switzerland
    J Physiol 497:849-56. 1996
    ..However, because of the changed/decreased afferent input no postural adjustments are generated...
  41. doi Body weight supported gait training: from laboratory to clinical setting
    V Dietz
    University Hospital Balgrist, Spinal Cord Injury Center, Zurich, Switzerland
    Brain Res Bull 78:I-VI. 2009
    ..Presently, individuals with complete SCI, spinal neuronal circuits undergo a degradation of their function 1 year after injury...
  42. ncbi Proprioceptive input overrides vestibulo-spinal drive during human locomotion
    V Dietz
    ParaCare, University Hospital Balgrist, Forchstr. 340, , Switzerland
    Neuroreport 12:2743-6. 2001
    ..It is suggested that the amount of proprioceptive feedback from the legs determines the influence of vestibulo-spinal input on body movement...
  43. ncbi Improving axonal growth and functional recovery after experimental spinal cord injury by neutralizing myelin associated inhibitors
    K Fouad
    Brain Research Institute, University of Zurich and Department of Biology ETH Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland
    Brain Res Brain Res Rev 36:204-12. 2001
    ..These observations, together with electrophysiological results, suggest that neuronal CNS circuits of mAb IN-1-treated animals can be rearranged, and that sprouting and regenerating axons form functionally meaningful connections...
  44. ncbi The influence of a clear layer on near-infrared spectrophotometry measurements using a liquid neonatal head phantom
    M Wolf
    Clinic for Neonatology, University Hospital, Zurich, Switzerland
    Phys Med Biol 44:1743-53. 1999
    ..3, 29.2, 23.4 and 16.6%. Concentration changes were underestimated by a factor of six to ten. This study demonstrates the need to develop algorithms which take into consideration anatomical structures...
  45. doi Concepts of aging with paralysis: implications for recovery and treatment
    M Wirz
    Spinal Cord Injury Center, Balgrist University Hospital, Zurich, Switzerland
    Handb Clin Neurol 109:77-84. 2012
    ..In addition, problems in general health (e.g., in circulation, kidney function, diabetes mellitus) may affect the functional independence of elderly subjects with SCI...
  46. doi Neuronal dysfunction in chronic spinal cord injury
    M Hubli
    Spinal Cord Injury Center, Balgrist University Hospital, Zurich, Switzerland
    Spinal Cord 49:582-7. 2011
    ..Training of spinal interneuronal circuits including the enhancement of an appropriate afferent input might serve as an intervention to prevent neuronal dysfunction after an SCI...
  47. ncbi Driven gait orthosis for improvement of locomotor training in paraplegic patients
    G Colombo
    Rehabilitation and Research Institute ParaCare, University Hospital Balgrist, Zurich, Switzerland
    Spinal Cord 39:252-5. 2001
    ..With the driven gait orthosis training sessions can be prolonged and workload of therapists can be reduced, and therefore, the automated training represents an alternative to the conventional therapy...
  48. ncbi Obstacle avoidance during human walking: H-reflex modulation during motor learning
    F Hess
    Balgrist University Hospital, Spinal Cord Injury Center, Forchstrasse 340, CH 8008, Zurich, Switzerland
    Exp Brain Res 151:82-9. 2003
    ..The observations made are probably less specific for this motor task (stepping over the obstacle), but rather associated with the increased attention required by the motor learning task during the first obstacle run...
  49. ncbi The influence of age on learning a locomotor task
    H J A van Hedel
    Spinal Cord Injury Center, Balgrist University Hospital, Forchstrasse 340, Zurich, CH 8008, Switzerland
    Clin Neurophysiol 115:2134-43. 2004
    ..The aim of this study was to evaluate differences between young and elderly subjects in the acquisition and performance of a precision locomotor task, with full and restricted vision...
  50. ncbi Treadmill training of paraplegic patients using a robotic orthosis
    G Colombo
    Paraplegic Center ParaCare, University Hospital Balgrist, Zurich, Switzerland
    J Rehabil Res Dev 37:693-700. 2000
    ..With the DGO the legs of patients with different degrees of paresis and spasticity could be trained for more than half an hour, and physiological gait patterns were obtained...
  51. ncbi Influence of vestibular and visual stimulation on split-belt walking
    B Marques
    Neurology Department, Zurich University Hospital, Frauenklinikstrasse 26, 8091, Zurich, Switzerland
    Exp Brain Res 183:457-63. 2007
    ..The missing effect during fast walking corroborates the findings by others that the influence of vestibular tone asymmetry on locomotion decreases at higher gait velocities...
  52. ncbi The amplitude of lower leg motor evoked potentials is a reliable measure when controlled for torque and motor task
    Hubertus J A van Hedel
    Spinal Cord Injury Center, Balgrist University Hospital, Forchstrasse 340, 8008, Zurich, Switzerland
    J Neurol 254:1089-98. 2007
    ..The study investigated the reliability of anterior tibial (TA) MEP measures controlled for dorsal flexion torque and motor task...
  53. ncbi Lumbar spinal stenosis: assessment of cauda equina involvement by electrophysiological recordings
    D Egli
    Spinal Cord Injury Center, University Hospital Balgrist, Forchstrasse 340, 8008 Zurich, Switzerland
    J Neurol 254:741-50. 2007
    ..All patients were assessed by neurological examination, electrophysiological recordings, and magnetic resonance imaging (MRI) of the lumbar spine. The electrophysiological recordings focused on spinal lumbar nerve involvement...
  54. pmc Obstacle avoidance during human walking: transfer of motor skill from one leg to the other
    H J A van Hedel
    ParaCare, Institute for Rehabilitation and Research at the University Hospital Balgrist, Zurich, Switzerland
    J Physiol 543:709-17. 2002
    ..It is hypothesised that the learning effects observed in the present experiments are mediated at a higher level (e.g. brainstem) of locomotor control...
  55. pmc Long term effects of locomotor training in spinal humans
    M Wirz
    ParaCare, Paraplegic Centre of the University Hospital Balgrist, Forchstrasse 340, CH-8008 Zurich, Switzerland
    J Neurol Neurosurg Psychiatry 71:93-6. 2001
    ..By contrast the EMG significantly fell in those with complete SCI. The results suggest a training induced plasticity of neuronal centres in the isolated spinal cord which may be of relevance for future interventional therapies...
  56. ncbi CO2 reactivity of the cerebral hemoglobin concentration in healthy term newborns measured by near infrared spectrophotometry
    V Dietz
    Department of Neonatology, University Hospital, Zurich, Switzerland
    Biol Neonate 75:85-90. 1999
    ..As the CO2 reactivity might be an indicator for infants at risk of cerebral damage, it is necessary to have data on the physiological range of this parameter...
  57. ncbi Transcutaneous functional electrical stimulation for grasping in subjects with cervical spinal cord injury
    S Mangold
    Automatic Control Laboratory, Swiss Federal Institute of Technology Zurich ETHZ, Zurich, Switzerland
    Spinal Cord 43:1-13. 2005
    ..Case series...
  58. doi Behavior of spinal neurons deprived of supraspinal input
    Volker Dietz
    Spinal Cord Injury Center, Balgrist University Hospital, Forchstrasse 340, 8008 Zurich, Switzerland
    Nat Rev Neurol 6:167-74. 2010
    ..Appropriate training and/or provision of afferent input to spinal neurons might help to prevent neuronal dysfunction in chronic SCI...
  59. ncbi Assessment of walking speed and distance in subjects with an incomplete spinal cord injury
    Hubertus J A van Hedel
    Spinal Cord Injury Center, Balgrist University Hospital, Zurich, Switzerland
    Neurorehabil Neural Repair 21:295-301. 2007
    ..Studies about testing preferred and maximum speeds in subjects with incomplete spinal cord injury are lacking...
  60. ncbi New technologies and concepts for rehabilitation in the acute phase of stroke: a collaborative matrix
    E M Siekierka
    Department of Neurology, University Hospital Zurich, Zurich, Switzerland
    Neurodegener Dis 4:57-69. 2007
    ..We also outline the neuroscientific basis of our approach, present our detailed clinical assessment protocol and provide preliminary results from patient testing of each of the three systems showing their viability for patient use...
  61. ncbi Socio-economic outcome of paraplegia compared to lower limb amputation
    A Cavigelli
    ParaCare, Paraplegic Centre, University Hospital Balgrist, Zurich, Switzerland
    Spinal Cord 40:174-7. 2002
    ..The socio-economic outcome was retrospectively compared between patients with traumatic lower limb amputation and those with paraplegia due to a spinal cord injury (SCI)...
  62. ncbi Standardized assessment of walking capacity after spinal cord injury: the European network approach
    H J A van Hedel
    Spinal Cord Injury Center, Balgrist University Hospital, Zurich, Switzerland
    Neurol Res 30:61-73. 2008
    ..Then, we investigated which categories of the WISCI II apply to SCI subjects who participated in the European Multicenter Study of Human Spinal Cord Injury (EM-SCI), and the relationship between the 10MWT and the TUG...
  63. ncbi Differential effect of spinal cord injury and functional impairment on human brain activation
    A Curt
    ParaCare, Institute for Rehabilitation and Research, University Hospital Balgrist, Zurich, Switzerland
    J Neurotrauma 19:43-51. 2002
    ..The effect of impaired afferent feedback and/or increased compensatory use of non-impaired limbs in SCI patients needs further evaluation...
  64. ncbi Reflex adaptations during treadmill walking with increased body load
    K Fouad
    Brain Research Institute, University and ETH Zurich, Winterthurerstr, 190, 8057 Zurich, Switzerland
    Exp Brain Res 137:133-40. 2001
    ..Load information is rather used to slowly modify the reflex response, to achieve the desired posture during walking...
  65. ncbi Muscle force and gait performance: relationships after spinal cord injury
    Markus Wirz
    Spinal Cord Injury Center, Balgrist University Hospital, Zurich, Switzerland
    Arch Phys Med Rehabil 87:1218-22. 2006
    ....
  66. ncbi Obstacle avoidance during human walking: effects of biomechanical constraints on performance
    Hubertus J van Hedel
    Spinal Cord Injury Center, Balgrist University Hospital, Forchstrasse 340, Ch 8008 Zurich, Switzerland
    Arch Phys Med Rehabil 85:972-9. 2004
    ..To determine whether fixation of the ankle joint, the knee joint, or both increasingly affects the performance of a newly learned task, that is, stepping over an obstacle...
  67. ncbi Transfer of motor performance in an obstacle avoidance task to different walking conditions
    Tania Lam
    Spinal Cord Injury Center, Balgrist University Hospital, Forchstrasse 340, 8008 Zurich, Switzerland
    J Neurophysiol 92:2010-6. 2004
    ..The results are discussed in the context of emerging concepts in the neural control of walking and motor learning...
  68. ncbi Assessing walking ability in subjects with spinal cord injury: validity and reliability of 3 walking tests
    Hubertus J van Hedel
    Spinal Cord Injury Center, Balgrist University Hospital, Zurich, Switzerland
    Arch Phys Med Rehabil 86:190-6. 2005
    ..To assess the validity and reliability of 3 timed walking tests (Timed Up & Go [TUG], 10-meter walk test [10MWT], 6-minute walk test) in subjects with spinal cord injury (SCI)...
  69. ncbi Effectiveness of automated locomotor training in patients with chronic incomplete spinal cord injury: a multicenter trial
    Markus Wirz
    Spinal Cord Injury Center, Balgrist University Hospital, Zurich, Switzerland
    Arch Phys Med Rehabil 86:672-80. 2005
    ..To determine whether automated locomotor training with a driven-gait orthosis (DGO) can increase functional mobility in people with chronic, motor incomplete spinal cord injury (SCI)...
  70. doi Recovery from a spinal cord injury: significance of compensation, neural plasticity, and repair
    Armin Curt
    Spinal Cord Injury Centre, Balgrist University Hospital, Forchstrasse 340, Zurich, Switzerland
    J Neurotrauma 25:677-85. 2008
    ..These findings support the assumption that functional recovery occurs by compensation, especially in cSCI and by neural plasticity leading to a greater improvement in iSCI. Relevant repair of damaged spinal pathways does not take place...
  71. doi Nogo-A antibodies and training reduce muscle spasms in spinal cord-injured rats
    Roman R Gonzenbach
    Brain Research Institute, University of Zurich, Winterthurerstrasse 190, Zurich, Switzerland
    Ann Neurol 68:48-57. 2010
    ....
  72. ncbi Repair of the injured spinal cord. A joint approach of basic and clinical research
    Anita D Buchli
    Brain Research Institute, University and ETH Zurich, Zurich, Switzerland
    Neurodegener Dis 4:51-6. 2007
    ....
  73. ncbi Providing the clinical basis for new interventional therapies: refined diagnosis and assessment of recovery after spinal cord injury
    A Curt
    Spinal Cord Injury Centre, University Hospital Balgrist, Switzerland
    Spinal Cord 42:1-6. 2004
    ..The project's aim is to establish objective, refined tools as a basis for monitoring the effects of new treatment strategies...
  74. doi Clinical algorithm for improved prediction of ambulation and patient stratification after incomplete spinal cord injury
    Björn Zörner
    Spinal Cord Injury Center, Balgrist University Hospital, Zurich, Switzerland
    J Neurotrauma 27:241-52. 2010
    ..These data provide evidence that a combination of predictors enables a reliable prediction of walking function and early patient stratification for clinical trials in miSCI...
  75. doi The occurrence of the Babinski sign in complete spinal cord injury
    Jens A Petersen
    Spinal Cord Injury Center, University Hospital Balgrist, Zurich, Switzerland
    J Neurol 257:38-43. 2010
    ..In complete SCI subjects, the occurrence of the BS is connected with spastic muscle tone. The absence of the BS is frequently due to associated peripheral nerve damage...
  76. doi Walking during daily life can be validly and responsively assessed in subjects with a spinal cord injury
    Hubertus J A van Hedel
    Spinal Cord Injury Center, Balgrist University Hospital Zurich, Switzerland
    Neurorehabil Neural Repair 23:117-24. 2009
    ..This study assessed the validity and responsiveness of the Spinal Cord Independence Measure (SCIM II) items indoor mobility, mobility for moderate distances, and outdoor mobility...
  77. ncbi Changes in activity after a complete spinal cord injury as measured by the Spinal Cord Independence Measure II (SCIM II)
    Brigitte Wirth
    Spinal Cord Injury Center, Balgrist University Hospital, Zurich, Switzerland
    Neurorehabil Neural Repair 22:145-53. 2008
    ..The Spinal Cord Independence Measure II (SCIM II) is an independence scale that was specifically developed for subjects with SCI. However, little is known about the changes in SCIM II scores during and after rehabilitation...
  78. ncbi Learning a high-precision locomotor task in patients with Parkinson's disease
    Hubertus J A van Hedel
    Spinal Cord Injury Center, Balgrist University Hospital, Zurich, Switzerland
    Mov Disord 21:406-11. 2006
    ..Restricting vision deteriorated performance in both groups. The similar performance of PD patients after task repetition might indicate that adequate training could improve adaptive locomotor behavior in PD patients...
  79. ncbi Impaired facilitation of motor evoked potentials in incomplete spinal cord injury
    Philipp Diehl
    Spinal Cord Injury Center, University Hospital Balgrist, Forchstrasse 340, 8008, Zurich, Switzerland
    J Neurol 253:51-7. 2006
    ..To improve the diagnosis of damaged spinal motor pathways in incomplete spinal cord injury (iSCI) by assessing the facilitation of lower limbs motor evoked potentials (MEP)...
  80. pmc G. Heiner Sell memorial lecture: neuronal plasticity after spinal cord injury: significance for present and future treatments
    Volker Dietz
    Spinal Cord Injury Center, University Hospital Balgrist, Zurich, Switzerland
    J Spinal Cord Med 29:481-8. 2006
    ....
  81. ncbi Magnetic stimulation of sacral roots for assessing the efferent neuronal pathways of lower urinary tract
    Biljana Rodic
    ParaCare, Institute for Rehabilitation and Research, University Hospital Balgrist, Zurich, Switzerland
    Muscle Nerve 26:486-91. 2002
    ..The method of SMS may be helpful for the evaluation of cases in which urodynamic studies remain inconclusive...
  82. doi Human bipeds use quadrupedal coordination during locomotion
    Volker Dietz
    Balgrist University Hospital, Spinal Cord Injury Center, Forchstrasse 340, Zurich, Switzerland
    Ann N Y Acad Sci 1164:97-103. 2009
    ..During obstacle avoidance steps, an anticipatory quadrupedal limb coordination is up-regulated, with an involvement of proximal arm muscles during the acquisition and performance of this precision locomotor task...
  83. doi Difficulty of elderly SCI subjects to translate motor recovery--"body function"--into daily living activities
    Werner Jakob
    Spinal Cord Injury Center, Balgrist University Hospital, Zurich, Switzerland
    J Neurotrauma 26:2037-44. 2009
    ..Therefore, rehabilitation approaches in elderly subjects should focus on functional training...
  84. doi Obstacle stepping in patients with Parkinson's disease. Complexity does influence performance
    Jan Michel
    Spinal Cord Injury Center, Balgrist University Hospital, Forchstrasse 340, 8008, Zurich, Switzerland
    J Neurol 256:457-63. 2009
    ..The present results extend findings from upper to lower limb movements, namely that PD subjects have difficulties in the performance of bilateral motor tasks...
  85. doi Levodopa therapy in incomplete spinal cord injury
    Oliver Maric
    Spinal Cord Injury Center, Balgrist University Hospital, Zurich, Switzerland
    J Neurotrauma 25:1303-7. 2008
    ..The combination of L-Dopa and physiotherapy had no greater effect on the outcome than placebo and physiotherapy. The possible reasons for the different effect of L-Dopa in stroke and iSCI subjects are discussed...
  86. doi Rehabilitation of locomotion after spinal cord injury
    Hubertus J A van Hedel
    SCI Research, Spinal Cord Injury Center, University of Zurich, Balgrist University Hospital, Forchstrasse 340, Ch 8008 Zurich, Switzerland
    Restor Neurol Neurosci 28:123-34. 2010
    ....
  87. ncbi Long-term changes in the tibia and radius bone mineral density following spinal cord injury
    E D de Bruin
    Laboratory for Biomechanics, Swiss Federal Institute of Technology, Zurich, Switzerland
    Spinal Cord 43:96-101. 2005
    ..A prospective inception cohort study with an observational analytic design in a spinal cord injury (SCI) centre hospital...
  88. doi Gait disorders
    V Dietz
    Balgrist University Hospital, Zurich, Switzerland
    Handb Clin Neurol 110:133-43. 2013
    ..Therapy should be directed toward functional training, which takes advantage of the plasticity of the nervous system. In the future a combination of repair and functional training will further improve the mobility of disabled patients...
  89. ncbi Tissue oxygen saturation measured by near infrared spectrophotometry correlates with arterial oxygen saturation during induced oxygenation changes in neonates
    M Wolf
    Clinic for Neonatology, University Hospital, Zurich, Switzerland
    Physiol Meas 21:481-91. 2000
    ..TOSa quantified changes reasonably correctly: delta TOSa = 0.90 delta SaO2. Changes in TOSc and TOSa were highly correlated (r2 = 0.98). These results are promising, but the large inter-individual variation requires further work...
  90. ncbi Ready for human spinal cord repair?
    Volker Dietz
    Spinal Cord Injury Centre, Balgrist University Hospital, Forchstr 340 8008 Zürich, Switzerland
    Brain 131:2240-2. 2008
  91. doi Computerized visual feedback: an adjunct to robotic-assisted gait training
    Raphael Banz
    Spinal Cord Injury Research, Balgrist University Hospital, Zurich, Switzerland
    Phys Ther 88:1135-45. 2008
    ....
  92. ncbi Changes in activity after a complete spinal cord injury as measured by the Spinal Cord Independence Measure II (SCIM II)
    Brigitte Wirth
    Spinal Cord Injury Center, Balgrist University Hospital, Zurich, Switzerland
    Neurorehabil Neural Repair 22:279-87. 2008
    ..The Spinal Cord Independence Measure II (SCIM II) is an independence scale that was specifically developed for subjects with SCI. However, little is know about the changes in SCIM II scores during and after rehabilitation...
  93. pmc SSEP analysis in surgery of idiopathic scoliosis: the influence of spine deformity and surgical approach
    Oliver Hausmann
    ParaCare, Swiss Paraplegic Center, Institute for Rehabilitation and Research, University Hospital Balgrist, Forchstrasse 340, 8008 Zurich, Switzerland
    Eur Spine J 12:117-23. 2003
    ..Even in clinically uneventful surgery, the postoperative t-SSEPs can be deteriorated depending on the surgical approach. This indicates a subclinical impact of spine surgery upon spinal cord function...
  94. pmc Standardized voluntary force measurement in a lower extremity rehabilitation robot
    Marc Bolliger
    Spinal Cord Injury Center, Balgrist University Hospital, Zurich, Switzerland
    J Neuroeng Rehabil 5:23. 2008
    ..A new method to assess isometric muscle force was implemented in the driven gait orthosis (DGO) Lokomat. To evaluate the capabilities of this new measurement method, inter- and intra-rater reliability were assessed...
  95. doi Neuropathic pain in spinal cord injury: significance of clinical and electrophysiological measures
    Susanne Wydenkeller
    Spinal Cord Injury Center, University Hospital Balgrist, Zurich, Forchstrasse 340, 8008 Zurich, Switzerland
    Eur J Neurosci 30:91-9. 2009
    ..These findings could be helpful for both the development of an objective diagnosis of bNP and for testing the effectiveness of new therapeutic agents...
  96. ncbi Spastic movement disorder: impaired reflex function and altered muscle mechanics
    Volker Dietz
    Spinal Cord Injury Centre, University of Zurich, Switzerland
    Lancet Neurol 6:725-33. 2007
    ..Antispastic drugs can accentuate paresis and therefore should be applied with caution in mobile patients...
  97. ncbi Phase-dependent modulation of short latency cutaneous reflexes during walking in man
    Bernke Christianne Maria Baken
    SMK Research, Sint Maartens Hospital, Nijmegen, The Netherlands
    Brain Res 1031:268-75. 2005
    ..It is concluded that P1 and P2 reflexes can appear independently from each other, but that their modulation in the step cycle is mostly quite similar in some phases of the step cycle (end swing)...
  98. ncbi Letter to the editor
    Edelle C Field-Fote
    Neurorehabil Neural Repair 20:233; author reply 233-4. 2006
  99. pmc Single joint perturbation during gait: preserved compensatory response pattern in spinal cord injured subjects
    Edelle C Field-Fote
    The Miami Project to Cure Paralysis, Miller School of Medicine, University of Miami, Miami, FL 33136, USA
    Clin Neurophysiol 118:1607-16. 2007
    ..The study aim was to examine whether supraspinal influences affect the behavior of complex electromyographic (EMG) responses to single limb perturbations during walking...
  100. ncbi Electromyographic activity associated with spontaneous functional recovery after spinal cord injury in rats
    Sibille Kaegi
    Brain Research Institute, University of Zurich and Department of Biology ETH Zurich, 8057 Zurich, Switzerland
    Eur J Neurosci 16:249-58. 2002
    ..Activity overlap between flexor and extensor muscles might be directly caused by altered descending input or by maladaptation of central pattern generating networks and/or sensory feedback...
  101. ncbi Differences in the EMG pattern of leg muscle activation during locomotion in Parkinson's disease
    Giovanni Albani
    Department of Neurology, IRCCS Italian Auxology Centre, Piancavallo, Verbania, Italy
    Funct Neurol 18:165-70. 2003
    ..Poor recruitment of the GM characterises parkinsonian gait in general; this pattern is much more marked in parkinsonian patients with freezing of gait, who show a loss of GM adaptation to variation of locomotion speed...