Bernhard Dichtl

Summary

Affiliation: University of Basel
Country: Switzerland

Publications

  1. pmc Functions for S. cerevisiae Swd2p in 3' end formation of specific mRNAs and snoRNAs and global histone 3 lysine 4 methylation
    Bernhard Dichtl
    Department of Cell Biology, Biozentrum, University of Basel, CH 4056 Basel, Switzerland
    RNA 10:965-77. 2004
  2. pmc Yhh1p/Cft1p directly links poly(A) site recognition and RNA polymerase II transcription termination
    Bernhard Dichtl
    Department of Cell Biology, Biozentrum, University of Basel, Klingelbergstrasse 70, CH 4056 Basel, Switzerland
    EMBO J 21:4125-35. 2002
  3. pmc The role of the yeast cleavage and polyadenylation factor subunit Ydh1p/Cft2p in pre-mRNA 3'-end formation
    Andrea Kyburz
    Department of Cell Biology, Biozentrum, University of Basel, Klingelbergstrasse 70, CH 4056 Basel, Switzerland
    Nucleic Acids Res 31:3936-45. 2003
  4. pmc Independent functions of yeast Pcf11p in pre-mRNA 3' end processing and in transcription termination
    Martin Sadowski
    Department of Cell Biology, Biozentrum, University of Basel, CH 4056 Basel, Switzerland
    EMBO J 22:2167-77. 2003
  5. pmc The role of the putative 3' end processing endonuclease Ysh1p in mRNA and snoRNA synthesis
    Monika Garas
    Biozentrum, University of Basel, CH 4056 Basel, Switzerland
    RNA 14:2671-84. 2008
  6. ncbi A role for SSU72 in balancing RNA polymerase II transcription elongation and termination
    Bernhard Dichtl
    Department of Cell Biology, Biozentrum, University of Basel, Klingelbergstrasse 70, CH 4056 Basel, Switzerland
    Mol Cell 10:1139-50. 2002
  7. ncbi Protein interactions within the Set1 complex and their roles in the regulation of histone 3 lysine 4 methylation
    Pierre Marie Dehé
    Laboratoire d InstabilitéduGénome et Cancérogénèse, Institut de Biologie Structurale et Microbiologie, CNRS, Marseille 13402, France
    J Biol Chem 281:35404-12. 2006
  8. pmc Functional analysis of yeast snoRNA and snRNA 3'-end formation mediated by uncoupling of cleavage and polyadenylation
    Mariangela Morlando
    Institut Pasteur Fondazione Cenci Bolognetti, Department of Genetics and Molecular Biology, University La Sapienza, 00185 Rome, Italy
    Mol Cell Biol 22:1379-89. 2002
  9. pmc Coupling between snoRNP assembly and 3' processing controls box C/D snoRNA biosynthesis in yeast
    Mariangela Morlando
    Department of Genetics and Molecular Biology, Institute Pasteur Cenci Bolognetti, University of Rome La Sapienza, Rome, Italy
    EMBO J 23:2392-401. 2004
  10. pmc Cordycepin-hypersensitive growth links elevated polyphosphate levels to inhibition of poly(A) polymerase in Saccharomyces cerevisiae
    Sandra Holbein
    Institute of Molecular Biology, University of Zurich, Zurich, Switzerland
    Nucleic Acids Res 36:353-63. 2008

Collaborators

  • Walter Keller
  • Rein Aasland
  • Alessandro Fatica
  • Florian M Freimoser
  • Mariangela Morlando
  • Martin Sadowski
  • Monika Garas
  • Sandra Holbein
  • Pierre Marie Dehé
  • Andrea Kyburz
  • Irene Bozzoni
  • Paolo Greco
  • Thomas P Werner
  • Agnieszka Wengi
  • Vincent Geli
  • Alfonso Rodriguez-Gil
  • Mercè Pamblanco
  • Assen Roguev
  • Vicente Tordera
  • Msau Mkandawire
  • Sebastián Chávez
  • Anna Shevchenko
  • Daniel Schaft
  • Regine Lebrun
  • Andrej Shevchenko
  • Lorena E Rosaleny
  • A Francis Stewart
  • Katarina Landsberg
  • Elisa Caffarelli
  • Monica Ballarino
  • Wolfgang Hubner

Detail Information

Publications11

  1. pmc Functions for S. cerevisiae Swd2p in 3' end formation of specific mRNAs and snoRNAs and global histone 3 lysine 4 methylation
    Bernhard Dichtl
    Department of Cell Biology, Biozentrum, University of Basel, CH 4056 Basel, Switzerland
    RNA 10:965-77. 2004
    ..We also provide evidence that the roles of Swd2p as component of CPF and SET1C are functionally independent. Taken together, our results establish a dual requirement for Swd2p in 3' end formation and histone tail modification...
  2. pmc Yhh1p/Cft1p directly links poly(A) site recognition and RNA polymerase II transcription termination
    Bernhard Dichtl
    Department of Cell Biology, Biozentrum, University of Basel, Klingelbergstrasse 70, CH 4056 Basel, Switzerland
    EMBO J 21:4125-35. 2002
    ..We propose that direct interactions of Yhh1p/Cft1p with both the RNA transcript and the CTD are required to communicate poly(A) site recognition to elongating pol II to initiate transcription termination...
  3. pmc The role of the yeast cleavage and polyadenylation factor subunit Ydh1p/Cft2p in pre-mRNA 3'-end formation
    Andrea Kyburz
    Department of Cell Biology, Biozentrum, University of Basel, Klingelbergstrasse 70, CH 4056 Basel, Switzerland
    Nucleic Acids Res 31:3936-45. 2003
    ....
  4. pmc Independent functions of yeast Pcf11p in pre-mRNA 3' end processing and in transcription termination
    Martin Sadowski
    Department of Cell Biology, Biozentrum, University of Basel, CH 4056 Basel, Switzerland
    EMBO J 22:2167-77. 2003
    ..We conclude that Pcf11p is a bifunctional protein and that transcript cleavage is not an obligatory step prior to RNAP II termination...
  5. pmc The role of the putative 3' end processing endonuclease Ysh1p in mRNA and snoRNA synthesis
    Monika Garas
    Biozentrum, University of Basel, CH 4056 Basel, Switzerland
    RNA 14:2671-84. 2008
    ..These observations suggest that Ysh1p has multiple roles in RNA synthesis and processing...
  6. ncbi A role for SSU72 in balancing RNA polymerase II transcription elongation and termination
    Bernhard Dichtl
    Department of Cell Biology, Biozentrum, University of Basel, Klingelbergstrasse 70, CH 4056 Basel, Switzerland
    Mol Cell 10:1139-50. 2002
    ..The sum of our analyses suggests a negative influence of Ssu72p on RNAP II during transcription that affects the commitment to either elongation or termination...
  7. ncbi Protein interactions within the Set1 complex and their roles in the regulation of histone 3 lysine 4 methylation
    Pierre Marie Dehé
    Laboratoire d InstabilitéduGénome et Cancérogénèse, Institut de Biologie Structurale et Microbiologie, CNRS, Marseille 13402, France
    J Biol Chem 281:35404-12. 2006
    ..Taken together, our results suggest that Set1C subunits stimulate Set1 catalytic activity all along active genes...
  8. pmc Functional analysis of yeast snoRNA and snRNA 3'-end formation mediated by uncoupling of cleavage and polyadenylation
    Mariangela Morlando
    Institut Pasteur Fondazione Cenci Bolognetti, Department of Genetics and Molecular Biology, University La Sapienza, 00185 Rome, Italy
    Mol Cell Biol 22:1379-89. 2002
    ..We propose a model in which CF IA functions in cleavage and polyadenylation of pre-mRNAs and, in combination with a different set of factors, in 3"-end formation of nonpolyadenylated polymerase II transcripts...
  9. pmc Coupling between snoRNP assembly and 3' processing controls box C/D snoRNA biosynthesis in yeast
    Mariangela Morlando
    Department of Genetics and Molecular Biology, Institute Pasteur Cenci Bolognetti, University of Rome La Sapienza, Rome, Italy
    EMBO J 23:2392-401. 2004
    ..These data suggest a mechanism of quality control in which efficient transcription and 3'-end formation occur only when nascent snoRNAs are successfully assembled into functional particles...
  10. pmc Cordycepin-hypersensitive growth links elevated polyphosphate levels to inhibition of poly(A) polymerase in Saccharomyces cerevisiae
    Sandra Holbein
    Institute of Molecular Biology, University of Zurich, Zurich, Switzerland
    Nucleic Acids Res 36:353-63. 2008
    ..Based on these observations, we suggest that binding of poly P to poly(A) polymerase negatively regulates its activity...
  11. doi Transcriptional ShortCUTs
    Bernhard Dichtl
    Institute of Molecular Biology, University of Zurich, CH 8057 Zurich, Switzerland
    Mol Cell 31:617-8. 2008
    ..2008) in Molecular Cell and Jenks et al. (2008) in Molecular and Cellular Biology reveals that regulated expression of central nucleotide synthesis pathway components directs start site-dependent RNA polymerase II termination...