C Dehio

Summary

Affiliation: University of Basel
Country: Switzerland

Publications

  1. pmc Intruders below the radar: molecular pathogenesis of Bartonella spp
    Alexander Harms
    Focal Area Infection Biology, Biozentrum, University of Basel, Switzerland
    Clin Microbiol Rev 25:42-78. 2012
  2. pmc Infection-associated type IV secretion systems of Bartonella and their diverse roles in host cell interaction
    Christoph Dehio
    Focal Area Infection Biology, Biozentrum of the University of Basel, Klingelbergstrasse 70, CH 4056 Basel, Switzerland
    Cell Microbiol 10:1591-8. 2008
  3. ncbi request reprint Bartonella-host-cell interactions and vascular tumour formation
    Christoph Dehio
    Division of Molecular Microbiology, Biozentrum, University of Basel, Klingelbergstrasse 70, CH 4056 Basel, Switzerland
    Nat Rev Microbiol 3:621-31. 2005
  4. pmc Isolation of Bartonella schoenbuchensis from Lipoptena cervi, a blood-sucking arthropod causing deer ked dermatitis
    Christoph Dehio
    Division of Molecular Microbiology, Biozentrum of the University of Basel, Klingelbergstr 70, CH 4056 Basel, Switzerland
    J Clin Microbiol 42:5320-3. 2004
  5. ncbi request reprint Molecular and cellular basis of bartonella pathogenesis
    Christoph Dehio
    Division of Molecular Microbiology, Biozentrum, University of Basel, 4056 Basel, Switzerland
    Annu Rev Microbiol 58:365-90. 2004
  6. ncbi request reprint Recent progress in understanding Bartonella-induced vascular proliferation
    Christoph Dehio
    Division of Molecular Microbiology, Biozentrum of the University of Basel, Klingelbergstrasse 70, CH 4056 Basel, Switzerland
    Curr Opin Microbiol 6:61-5. 2003
  7. ncbi request reprint Bartonella schoenbuchii sp. nov., isolated from the blood of wild roe deer
    C Dehio
    Abt Molekulare Mikrobiologie, Biozentrum der Universitat Basel, Switzerland
    Int J Syst Evol Microbiol 51:1557-65. 2001
  8. ncbi request reprint Bartonella interactions with endothelial cells and erythrocytes
    C Dehio
    Dept of Molecular Microbiology, Biozentrum of the University of Basel, Klingelbergstrasse 70, CH 4056, Basel, Switzerland
    Trends Microbiol 9:279-85. 2001
  9. pmc Invasion and persistent intracellular colonization of erythrocytes. A unique parasitic strategy of the emerging pathogen Bartonella
    R Schulein
    Biozentrum of the University of Basel, Department of Molecular Microbiology, CH 4056 Basel, Switzerland
    J Exp Med 193:1077-86. 2001
  10. doi request reprint Distinct activities of Bartonella henselae type IV secretion effector proteins modulate capillary-like sprout formation
    F Scheidegger
    Focal Area Infection Biology Biozentrum, University of Basel, Switzerland
    Cell Microbiol 11:1088-101. 2009

Collaborators

Detail Information

Publications33

  1. pmc Intruders below the radar: molecular pathogenesis of Bartonella spp
    Alexander Harms
    Focal Area Infection Biology, Biozentrum, University of Basel, Switzerland
    Clin Microbiol Rev 25:42-78. 2012
    ....
  2. pmc Infection-associated type IV secretion systems of Bartonella and their diverse roles in host cell interaction
    Christoph Dehio
    Focal Area Infection Biology, Biozentrum of the University of Basel, Klingelbergstrasse 70, CH 4056 Basel, Switzerland
    Cell Microbiol 10:1591-8. 2008
    ..The T4SSs laterally acquired by the bartonellae have thus adopted highly diverse functions during infection, highlighting their versatility as pathogenicity factors...
  3. ncbi request reprint Bartonella-host-cell interactions and vascular tumour formation
    Christoph Dehio
    Division of Molecular Microbiology, Biozentrum, University of Basel, Klingelbergstrasse 70, CH 4056 Basel, Switzerland
    Nat Rev Microbiol 3:621-31. 2005
    ....
  4. pmc Isolation of Bartonella schoenbuchensis from Lipoptena cervi, a blood-sucking arthropod causing deer ked dermatitis
    Christoph Dehio
    Division of Molecular Microbiology, Biozentrum of the University of Basel, Klingelbergstr 70, CH 4056 Basel, Switzerland
    J Clin Microbiol 42:5320-3. 2004
    ..The role of B. schoenbuchensis in the etiology of deer ked dermatitis should be further investigated...
  5. ncbi request reprint Molecular and cellular basis of bartonella pathogenesis
    Christoph Dehio
    Division of Molecular Microbiology, Biozentrum, University of Basel, 4056 Basel, Switzerland
    Annu Rev Microbiol 58:365-90. 2004
    ..This review summarizes our understanding of Bartonella-host cell interactions and the molecular mechanisms of bacterial virulence and persistence. In addition, current controversies and unanswered questions in this area are highlighted...
  6. ncbi request reprint Recent progress in understanding Bartonella-induced vascular proliferation
    Christoph Dehio
    Division of Molecular Microbiology, Biozentrum of the University of Basel, Klingelbergstrasse 70, CH 4056 Basel, Switzerland
    Curr Opin Microbiol 6:61-5. 2003
    ..Given that bartonellae effectively adhere to and invade endothelial cells, their ability to trigger angioproliferation might represent a dedicated pathogenic strategy for expanding the bacterial host cell habitat...
  7. ncbi request reprint Bartonella schoenbuchii sp. nov., isolated from the blood of wild roe deer
    C Dehio
    Abt Molekulare Mikrobiologie, Biozentrum der Universitat Basel, Switzerland
    Int J Syst Evol Microbiol 51:1557-65. 2001
    ..The type strain R1T of Bartonella schoenbuchii has been deposited in the National Collection of Type Cultures as NCTC 13165T and the Deutsche Sammlung von Mikroorganismen und Zellkulturen as DSM 13525T...
  8. ncbi request reprint Bartonella interactions with endothelial cells and erythrocytes
    C Dehio
    Dept of Molecular Microbiology, Biozentrum of the University of Basel, Klingelbergstrasse 70, CH 4056, Basel, Switzerland
    Trends Microbiol 9:279-85. 2001
    ..Based on the establishment of bacterial genetics and appropriate infection models, recent work has begun to elucidate the cell and molecular biology of these unusual pathogen-host cell interactions...
  9. pmc Invasion and persistent intracellular colonization of erythrocytes. A unique parasitic strategy of the emerging pathogen Bartonella
    R Schulein
    Biozentrum of the University of Basel, Department of Molecular Microbiology, CH 4056 Basel, Switzerland
    J Exp Med 193:1077-86. 2001
    ..Our findings unravel a unique bacterial persistence strategy adapted to a nonhemolytic intracellular colonization of erythrocytes that preserves the pathogen for efficient transmission by blood-sucking arthropods...
  10. doi request reprint Distinct activities of Bartonella henselae type IV secretion effector proteins modulate capillary-like sprout formation
    F Scheidegger
    Focal Area Infection Biology Biozentrum, University of Basel, Switzerland
    Cell Microbiol 11:1088-101. 2009
    ....
  11. ncbi request reprint The VirB/VirD4 type IV secretion system of Bartonella is essential for establishing intraerythrocytic infection
    Ralf Schulein
    Division of Microbiology, Biozentrum of the University of Basel, Switzerland
    Mol Microbiol 46:1053-67. 2002
    ..This analysis of defined mutants in an in vivo model identified components of the VirB/VirD4 T4SS as the first bona fide pathogenicity factors in Bartonella...
  12. ncbi request reprint Genomic analysis of Bartonella identifies type IV secretion systems as host adaptability factors
    Henri L Saenz
    Focal Area Infection Biology, Biozentrum, University of Basel, CH 4056 Basel, Switzerland
    Nat Genet 39:1469-76. 2007
    ..bacilliformis, and one has been lost by deletion. The 14 pathogenicity genes specific for the radiating lineage encode two laterally acquired type IV secretion systems, suggesting that these systems have a role in host adaptability...
  13. ncbi request reprint Bacterial persistence within erythrocytes: a unique pathogenic strategy of Bartonella spp
    Anja Seubert
    Department of Molecular Microbiology, Biozentrum of the University of Basel, Switzerland
    Int J Med Microbiol 291:555-60. 2002
    ..Though required for establishing haemotropic infection, it remains to be demonstrated if this type IV secretion system is necessary for colonisation of the primary niche or for the subsequent colonisation of erythrocytes...
  14. doi request reprint A translocated protein of Bartonella henselae interferes with endocytic uptake of individual bacteria and triggers uptake of large bacterial aggregates via the invasome
    Thomas A Rhomberg
    Focal Area Infection Biology, Biozentrum of the University of Basel, CH 4056 Basel, Switzerland
    Cell Microbiol 11:927-45. 2009
    ....
  15. ncbi request reprint Virulence-associated type IV secretion systems of Bartonella
    Gunnar Schröder
    Division of Molecular Microbiology, Biozentrum of the University of Basel, CH 4056 Basel, Switzerland
    Trends Microbiol 13:336-42. 2005
    ....
  16. pmc A bipartite signal mediates the transfer of type IV secretion substrates of Bartonella henselae into human cells
    Ralf Schulein
    Division of Molecular Microbiology, Biozentrum, University of Basel, Klingelbergstrasse 70, 4056 Basel, Switzerland
    Proc Natl Acad Sci U S A 102:856-61. 2005
    ..Conjugative relaxases may thus represent the evolutionary origin of the here defined T4S signal for protein transfer into human cells...
  17. ncbi request reprint Characterization of the cryptic plasmid pBGR1 from Bartonella grahamii and construction of a versatile Escherichia coli-Bartonella spp. shuttle cloning vector
    Anja Seubert
    Division of Molecular Microbiology, Biozentrum of the University of Basel, Basel, Switzerland
    Plasmid 49:44-52. 2003
    ..tribocorum during in vivo passage in a rat model in the absence of antibiotic selection. The small size and stability of these shuttle cloning vectors should render them particularly valuable for genetic studies in Bartonella spp...
  18. ncbi request reprint The VirB type IV secretion system of Bartonella henselae mediates invasion, proinflammatory activation and antiapoptotic protection of endothelial cells
    Michael C Schmid
    Division of Molecular Microbiology, Biozentrum, University of Basel, Klingelbergstrasse 70, 4056 Basel, Switzerland
    Mol Microbiol 52:81-92. 2004
    ..We conclude that the VirB T4SS is a major virulence determinant of B. henselae, required for targeting multiple endothelial cell functions exploited by this vasculotropic pathogen...
  19. pmc A translocated bacterial protein protects vascular endothelial cells from apoptosis
    Michael C Schmid
    Division of Molecular Microbiology, Biozentrum, University of Basel, Basel, Switzerland
    PLoS Pathog 2:e115. 2006
    ....
  20. ncbi request reprint Proteomic analysis of the sarcosine-insoluble outer membrane fraction of the bacterial pathogen Bartonella henselae
    Thomas A Rhomberg
    Division of Molecular Microbiology, Biozentrum of the University of Basel, Basel, Switzerland
    Proteomics 4:3021-33. 2004
    ..This study provides novel insights into the membrane biology and the associated putative virulence factors of this pathogen of increasing medical importance...
  21. pmc The BatR/BatS two-component regulatory system controls the adaptive response of Bartonella henselae during human endothelial cell infection
    Maxime Quebatte
    Focal Area Infection Biology, Biozentrum, University of Basel, Klingelbergstrasse 70, CH 4056 Basel, Switzerland
    J Bacteriol 192:3352-67. 2010
    ....
  22. ncbi request reprint Signature-tagged mutagenesis: technical advances in a negative selection method for virulence gene identification
    Henri L Saenz
    Division of Molecular Microbiology, Biozentrum, University of Basel, Klingelbergstrasse 70, 4056 Basel, Switzerland
    Curr Opin Microbiol 8:612-9. 2005
    ..These advances promoted substantially the application range and versatility of the STM method...
  23. ncbi request reprint A bacterial conjugation machinery recruited for pathogenesis
    Anja Seubert
    Division of Molecular Microbiology, Biozentrum of the University of Basel, Klingelbergstrasse 70, CH 4056 Basel, Switzerland
    Mol Microbiol 49:1253-66. 2003
    ....
  24. ncbi request reprint Role of PlGF in the intra- and intermolecular cross talk between the VEGF receptors Flt1 and Flk1
    Monica Autiero
    The Center for Transgene Technology and Gene Therapy, Flanders Interuniversity Institute for Biotechnology, KULeuven, Leuven, B 3000, Belgium
    Nat Med 9:936-43. 2003
    ....
  25. ncbi request reprint Coordinated activation of VEGFR-1 and VEGFR-2 is a potent arteriogenic stimulus leading to enhancement of regional perfusion
    Alexander Babiak
    Department of Internal Medicine II, Ulm University Medical Center, Ulm Germany
    Cardiovasc Res 61:789-95. 2004
    ..The purpose of this study was to identify which of the VEGF receptors are involved in arteriogenesis in vivo...
  26. ncbi request reprint Characterization of genes involved in long-term bacteremia in mice by Bartonella birtlesii
    Maria Mavris
    UMR 956 BIPAR, Ecole Nationale Veterinaire d Alfort, Maisons Alfort, France
    Ann N Y Acad Sci 1063:312-4. 2005
  27. ncbi request reprint Functional interactions between type IV secretion systems involved in DNA transfer and virulence
    Héctor D de Paz
    Departamento de Biología Molecular Unidad Asociada al CIB CSIC, Universidad de Cantabria, C Herrera Oria s n, 39011 Santander, Spain
    Microbiology 151:3505-16. 2005
    ....
  28. ncbi request reprint An engineered heparin-binding form of VEGF-E (hbVEGF-E). Biological effects in vitro and mobilizatiion of precursor cells
    Matthias Heil
    Department of Experimental Cardiology, Molecular Cell Biology, Max Planck Institute for Physiological and Clinical Research, Bad Nauheim, Germany
    Angiogenesis 6:201-11. 2003
    ..These findings suggest that both VEGFR-1 and VEGFR-2 are involved in stem cell mobilization...
  29. ncbi request reprint Bartonella bovis Bermond et al. sp. nov. and Bartonella capreoli sp. nov., isolated from European ruminants
    Delphine Bermond
    Institut de Bacteriologie de la Faculte de Medecine, Universite Louis Pasteur, Hĵpitaux Universitaires de Strasbourg, France
    Int J Syst Evol Microbiol 52:383-90. 2002
    ..Hybridization values when testing type strains of recognized Bartonella species, obtained with the nuclease/trichloroacetic acid method, support the creation of two novel species...
  30. pmc Characterization of the genome composition of Bartonella koehlerae by microarray comparative genomic hybridization profiling
    Hillevi L Lindroos
    Department of Molecular Evolution, Evolutionary Biology Center, Norbyvagen 18C, 752 36 Uppsala, Sweden
    J Bacteriol 187:6155-65. 2005
    ..Rather, the results underscore the instability of the genomic islands even within bacterial populations adapted to the same host-vector system, as in the case of B. henselae and B. koehlerae...
  31. ncbi request reprint Structure and biological activity of the short-chain lipopolysaccharide from Bartonella henselae ATCC 49882T
    Ulrich Zahringer
    Research Center Borstel, Leibniz Center for Medicine and Biosciences, 23845 Borstel, Germany
    J Biol Chem 279:21046-54. 2004
    ..g. Legionella and Chlamydia), may provide the molecular basis for low endotoxic potency...
  32. ncbi request reprint VEGF-A and PlGF-1 stimulate chemotactic migration of human mesenchymal progenitor cells
    Jörg Fiedler
    Orthopaedic Department, Division for Biochemistry of Joint and Connective Tissue Diseases, University of Ulm, Ulm, Germany
    Biochem Biophys Res Commun 334:561-8. 2005
    ....
  33. ncbi request reprint Genome-wide analysis of transcriptional hierarchy and feedback regulation in the flagellar system of Helicobacter pylori
    Eike Niehus
    Institute of Hygiene and Microbiology, University of Wuerzburg, Josef Schneider Strasse 2, D 97080 Wuerzburg, Germany
    Mol Microbiol 52:947-61. 2004
    ..A true master regulator of flagellar biosynthesis is absent in H. pylori, consistent with the essential role of flagellar motility and chemotaxis for this organism...