C A Daubenberger

Summary

Affiliation: University of Basel
Country: Switzerland

Publications

  1. ncbi request reprint Identification and recombinant expression of glyceraldehyde-3-phosphate dehydrogenase of Plasmodium falciparum
    C A Daubenberger
    Swiss Tropical Institute, Molecular Immunology, Socinstrasse 57, 4002, Basel, Switzerland
    Gene 246:255-64. 2000
  2. ncbi request reprint Identification and characterization of heme-interacting proteins in the malaria parasite, Plasmodium falciparum
    Naomi Campanale
    Department of Biochemistry and Co operative Research Centre for Diagnostics, La Trobe University, Melbourne 3086, Victoria, Australia
    J Biol Chem 278:27354-61. 2003
  3. ncbi request reprint Structural and functional characterisation of the Toll like receptor 9 of Aotus nancymaae, a non-human primate model for malaria vaccine development
    Rolf Spirig
    Department of Medical Parasitology and Biology of Infection, Molecular Immunology, Swiss Tropical Institute, Socinstrasse 57, 4002 Basel, Switzerland
    Immunogenetics 57:283-8. 2005
  4. pmc High-resolution genotyping and mapping of recombination and gene conversion in the protozoan Theileria parva using whole genome sequencing
    Sonal Henson
    International Livestock Research Institute, Nairobi 00100, Kenya
    BMC Genomics 13:503. 2012
  5. doi request reprint Development of influenza virosome-based synthetic malaria vaccines
    Claudia A Daubenberger
    Swiss Tropical Institute, Molecular Immunology, Socinstrasse 57, 4002 Basel, Switzerland 41 61 2848217 41 61 2718654
    Expert Opin Drug Discov 3:415-23. 2008
  6. ncbi request reprint Flow cytometric analysis on cross-reactivity of human-specific CD monoclonal antibodies with splenocytes of Aotus nancymaae, a non-human primate model for biomedical research
    Claudia A Daubenberger
    Swiss Tropical Institute, Department of Medical Parasitology and Biology of Infection, Molecular Immunology, Socinstrasse 57, 4002 Basel, Switzerland
    Vet Immunol Immunopathol 119:14-20. 2007
  7. pmc Identification and characterization of a conserved, stage-specific gene product of Plasmodium falciparum recognized by parasite growth inhibitory antibodies
    Claudia A Daubenberger
    Molecular Immunology, Swiss Tropical Institute, Socinstrasse 57, 4002 Basel, Switzerland
    Infect Immun 71:2173-81. 2003
  8. ncbi request reprint Amino acid dimorphism and parasite immune evasion: cellular immune responses to a promiscuous epitope of Plasmodium falciparum merozoite surface protein 1 displaying dimorphic amino acid polymorphism are highly constrained
    Claudia A Daubenberger
    Swiss Tropical Institute, Socinstrasse 57, CH 4002 Basel, Switzerland
    Eur J Immunol 32:3667-77. 2002
  9. ncbi request reprint First clinical trial of purified, irradiated malaria sporozoites in humans
    Claudia A Daubenberger
    Swiss Tropical and Public Health Institute, Department of Medical Parasitology and Infection Biology, Socinstr 57, CH 4002 Basel, Switzerland
    Expert Rev Vaccines 11:31-3. 2012
  10. ncbi request reprint Functional and structural similarity of V gamma 9V delta 2 T cells in humans and Aotus monkeys, a primate infection model for Plasmodium falciparum malaria
    C A Daubenberger
    Department of Molecular Immunology, Swiss Tropical Institute, Basel, Switzerland
    J Immunol 167:6421-30. 2001

Collaborators

Detail Information

Publications20

  1. ncbi request reprint Identification and recombinant expression of glyceraldehyde-3-phosphate dehydrogenase of Plasmodium falciparum
    C A Daubenberger
    Swiss Tropical Institute, Molecular Immunology, Socinstrasse 57, 4002, Basel, Switzerland
    Gene 246:255-64. 2000
    ..Antiserum raised against the recombinantly expressed enzyme detected specifically all developmental stages of cultured P. falciparum blood-stage parasites...
  2. ncbi request reprint Identification and characterization of heme-interacting proteins in the malaria parasite, Plasmodium falciparum
    Naomi Campanale
    Department of Biochemistry and Co operative Research Centre for Diagnostics, La Trobe University, Melbourne 3086, Victoria, Australia
    J Biol Chem 278:27354-61. 2003
    ..Inhibition of this pathway may drive flux through the pentose phosphate pathway ensuring sufficient production of reducing equivalents to counteract the oxidative stress induced by FP build-up...
  3. ncbi request reprint Structural and functional characterisation of the Toll like receptor 9 of Aotus nancymaae, a non-human primate model for malaria vaccine development
    Rolf Spirig
    Department of Medical Parasitology and Biology of Infection, Molecular Immunology, Swiss Tropical Institute, Socinstrasse 57, 4002 Basel, Switzerland
    Immunogenetics 57:283-8. 2005
    ..The high level of sequence conservation of Aona-TLR-9 reinforces the suitability of A. nancymaae as animal model for malaria subunit vaccine development...
  4. pmc High-resolution genotyping and mapping of recombination and gene conversion in the protozoan Theileria parva using whole genome sequencing
    Sonal Henson
    International Livestock Research Institute, Nairobi 00100, Kenya
    BMC Genomics 13:503. 2012
    ....
  5. doi request reprint Development of influenza virosome-based synthetic malaria vaccines
    Claudia A Daubenberger
    Swiss Tropical Institute, Molecular Immunology, Socinstrasse 57, 4002 Basel, Switzerland 41 61 2848217 41 61 2718654
    Expert Opin Drug Discov 3:415-23. 2008
    ..Results/conclusion: The great potential of influenza virosomes as a flexible, human-compatible antigen delivery platform for the development of a multivalent malaria subunit vaccine is described...
  6. ncbi request reprint Flow cytometric analysis on cross-reactivity of human-specific CD monoclonal antibodies with splenocytes of Aotus nancymaae, a non-human primate model for biomedical research
    Claudia A Daubenberger
    Swiss Tropical Institute, Department of Medical Parasitology and Biology of Infection, Molecular Immunology, Socinstrasse 57, 4002 Basel, Switzerland
    Vet Immunol Immunopathol 119:14-20. 2007
    ..This novel panel of A. nancymaae reactive mAb will increase the potential to explore complex host-pathogen interactions in non-human primate animal models, particularly in malaria vaccine research...
  7. pmc Identification and characterization of a conserved, stage-specific gene product of Plasmodium falciparum recognized by parasite growth inhibitory antibodies
    Claudia A Daubenberger
    Molecular Immunology, Swiss Tropical Institute, Socinstrasse 57, 4002 Basel, Switzerland
    Infect Immun 71:2173-81. 2003
    ..falciparum. In summary, we describe a novel stage-specifically expressed, highly conserved gene product of P. falciparum that is recognized by parasite growth inhibitory antibodies...
  8. ncbi request reprint Amino acid dimorphism and parasite immune evasion: cellular immune responses to a promiscuous epitope of Plasmodium falciparum merozoite surface protein 1 displaying dimorphic amino acid polymorphism are highly constrained
    Claudia A Daubenberger
    Swiss Tropical Institute, Socinstrasse 57, CH 4002 Basel, Switzerland
    Eur J Immunol 32:3667-77. 2002
    ..Lack of productive triggering of the TCR by MHC/variant peptide ligand complexes thus seems to be the characteristic feature of parasite immune evasion associated with antigen dimorphism...
  9. ncbi request reprint First clinical trial of purified, irradiated malaria sporozoites in humans
    Claudia A Daubenberger
    Swiss Tropical and Public Health Institute, Department of Medical Parasitology and Infection Biology, Socinstr 57, CH 4002 Basel, Switzerland
    Expert Rev Vaccines 11:31-3. 2012
    ..Further studies using PfSPZ and the intravenous route in humans are warranted to fully explore the potential of purified, attenuated sporozoites for malaria vaccine development...
  10. ncbi request reprint Functional and structural similarity of V gamma 9V delta 2 T cells in humans and Aotus monkeys, a primate infection model for Plasmodium falciparum malaria
    C A Daubenberger
    Department of Molecular Immunology, Swiss Tropical Institute, Basel, Switzerland
    J Immunol 167:6421-30. 2001
    ..The structural and functional conservation of Vgamma9Vdelta2 T cells in A. nancymaae and humans implicates a functionally important and evolutionary conserved mechanism of recognition of phosphorylated microbial metabolites...
  11. ncbi request reprint Herpesvirus saimiri transformed T cells and peripheral blood mononuclear cells restimulate identical antigen-specific human T cell clones
    C A Daubenberger
    Molecular Immunology, Swiss Tropical Institute, Socinstrasse 57, CH 4002 Basel, Switzerland
    J Immunol Methods 254:99-108. 2001
    ..This method might be particularly significant in clinical trials of immune intervention strategies...
  12. ncbi request reprint TLR9 agonists as adjuvants for prophylactic and therapeutic vaccines
    Claudia A Daubenberger
    Swiss Tropical Institute, Department of Medical Parasitology and Infection Biology, Socinstrasse 57, 4002 Basel, Switzerland
    Curr Opin Mol Ther 9:45-52. 2007
    ..Recent advances in the development and utility of TLR9 agonists in prophylactic or therapeutic vaccines against infectious diseases are focused on...
  13. pmc Bovine gammadelta T-cell responses to the intracellular protozoan parasite Theileria parva
    C A Daubenberger
    International Livestock Research Institute ILRI, Nairobi, Kenya
    Infect Immun 67:2241-9. 1999
    ..These results suggest that bovine gammadelta T cells are activated by and lyse T. parva-infected cells by recognizing conserved parasite-induced or parasite-derived antigens in an MHC-unrestricted fashion...
  14. ncbi request reprint The N'-terminal domain of glyceraldehyde-3-phosphate dehydrogenase of the apicomplexan Plasmodium falciparum mediates GTPase Rab2-dependent recruitment to membranes
    Claudia A Daubenberger
    Molecular Immunology, Swiss Tropical Institute, Socinstr 57, CH 4002 Basel, Switzerland
    Biol Chem 384:1227-37. 2003
    ..Together, these results suggest that pfGAPDH exerts non-glycolytic function(s) in P. falciparum, possibly including a role in vesicular transport and biogenesis of apical organelles...
  15. doi request reprint Contribution of influenza immunity and virosomal-formulated synthetic peptide to cellular immune responses in a phase I subunit malaria vaccine trial
    Elisabetta Peduzzi
    Swiss Tropical Institute, Molecular Immunology, CH 4002 Basel, Switzerland
    Clin Immunol 127:188-97. 2008
    ..Our results support the view that IRIV constitute a safe antigen delivery system for induction of peptide-specific immune responses in human populations...
  16. ncbi request reprint Characterization of a reduced peptide bond analogue of a promiscuous CD4 T cell epitope derived from the Plasmodium falciparum malaria vaccine candidate merozoite surface protein 1
    Max Bastian
    Swiss Tropical Institute, Molecular Immunology, Socinstrasse 57, CH 4002 Basel, Switzerland
    Mol Immunol 41:775-84. 2004
    ..27 recognized best this particular pseudo-peptide in competition ELISA experiments and its immunogenicity in out-bred Aotus monkeys was superior to that of the parent peptide eliciting antibodies cross-reactive with native MSP-1...
  17. ncbi request reprint Sequence and expression of MHC-DPB1 molecules of the New World monkey Aotus nancymaae, a primate model for Plasmodium falciparum
    Diana Diaz
    Swiss Tropical Institute, Socinstrasse 57, 4002 Basel, Switzerland
    Immunogenetics 54:251-9. 2002
    ..Aona-DP heterodimers are expressed on the surface of Aotus cells, as detected by staining with a cross-reactive monoclonal antibody, and can therefore present antigenic peptides to the cellular immune system...
  18. doi request reprint Identification of a synthetic peptide inducing cross-reactive antibodies binding to Rhipicephalus (Boophilus) decoloratus, Rhipicephalus (Boophilus) microplus, Hyalomma anatolicum anatolicum and Rhipicephalus appendiculatus BM86 homologues
    Nadja Kopp
    Swiss Tropical Institute, Department of Medical Parasitology and Infection Biology, Socinstrasse 57, 4002 Basel, Switzerland
    Vaccine 28:261-9. 2009
    ..Our results indicate that broadly cross-reactive tick gut binding antibodies can be induced after immunization with a synthetic peptide derived from the protein BD86...
  19. ncbi request reprint Safety, tolerability and immunogenicity of new formulations of the Plasmodium falciparum malaria peptide vaccine SPf66 combined with the immunological adjuvant QS-21
    Oscar Kashala
    Aquila Biopharmaceuticals Inc, Framingham, MA 01702, USA
    Vaccine 20:2263-77. 2002
    ..These observations demonstrate that the use of QS-21 can substantially enhance the immunogenicity of peptide vaccines, such as SPf66...
  20. ncbi request reprint Systemic suppression of interferon-gamma responses in Buruli ulcer patients resolves after surgical excision of the lesions caused by the extracellular pathogen Mycobacterium ulcerans
    Dorothy Yeboah-Manu
    Noguchi Memorial Institute for Medical Research, University of Ghana, Legon
    J Leukoc Biol 79:1150-6. 2006
    ..ulcerans bacteria...