Research Topics
| Antonio CozzioSummaryAffiliation: University Hospital Country: Switzerland Publications
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Detail Information
Publications
Intra-lesional low-dose interferon alpha2a therapy for primary cutaneous marginal zone B-cell lymphomaAntonio Cozzio
Department of Dermatology, University Hospital of Zurich, Zurich, Switzerland
Leuk Lymphoma 47:865-9. 2006..All other patients remained free of disease. Thus, intra-lesional IFNalpha2a may represent a valuable alternative to surgery and radiotherapy as first-line treatment of pcMZL...
Febrile ulceronecrotic Mucha-Habermann disease with clonality: a cutaneous T-cell lymphoma entity?Antonio Cozzio
Department of Dermatology, University Hospital of Zurich, Switzerland
J Am Acad Dermatol 51:1014-7. 2004..Here, we report two cases of FUMHD with monoclonal T-cell population, as detected by Southern blot analysis. We propose that clonal FUMHD represents a cutaneous T-cell lymphoma entity...
Cutaneous malignant lymphomas: update 2006Gunter Burg
Dept of Dermatology, University Hospital, Zurich, Switzerland
J Dtsch Dermatol Ges 4:914-33. 2006..Besides the classical options for therapy, there are new and "experimental" strategies, the efficacy of which has to be studied in clinical trials...
Recent advances in cutaneous lymphomasReinhard Dummer
Department of Dermatology, University Hospital Zurich, Gloriastrasse 31, CH 8091 Zurich, Switzerland
J Dermatol Sci 48:157-67. 2007....
Primary cutaneous B-cell lymphomas - clinicopathological, prognostic and therapeutic characterisation of 54 cases according to the WHO-EORTC classification and the ISCL/EORTC TNM classification system for primary cutaneous lymphomas other than mycosis funPhilippa Golling
Department of Dermatology, Cutaneous Lymphoma Study Group, University Hospital, Zurich, Switzerland
Leuk Lymphoma 49:1094-103. 2008..Surgical excision or radiotherapy is highly effective in pcMZL and pcFCL...
Pathogenesis and therapy of cutaneous lymphomas--progress or impasse?Reinhard Dummer
Department of Dermatology, University Hospital Zurich, Zurich, Switzerland
Exp Dermatol 15:392-400. 2006....
WHO/EORTC classification of cutaneous lymphomas 2005: histological and molecular aspectsGunter Burg
Department of Dermatology, University Hospital Zurich, Switzerland
J Cutan Pathol 32:647-74. 2005..These findings always have to be interpreted in the context of the clinical features and biologic behavior...
CD4+CD56+ hematodermic neoplasms bear a plasmacytoid dendritic cell phenotypeMirjana Urosevic
Department of Dermatology, University Hospital Zurich, Zurich 8091, Switzerland
Hum Pathol 36:1020-4. 2005..MxA protein, representing the surrogate marker for lesional type I interferon activity, was expressed in 4 of 5 evaluated cases. Our findings further substantiate the putative pDC origin of CD4+CD56+ HNs...
Granulomatous slack skin responds to UVA1 phototherapyPatrick A Oberholzer
Department of Dermatology, University Hospital Zurich, Zurich, Switzerland
Dermatology 219:268-71. 2009..A follow-up 12 months after phototherapy showed continued treatment benefit. To our knowledge, this is the first report describing the successful use of UVA1 (340-400 nm) phototherapy in a patient with GSS...
Cutaneous lymphomas: molecular pathways leading to new drugsReinhard Dummer
Department of Dermatology, University Hospital Zurich, Zurich, Switzerland
J Invest Dermatol 132:517-25. 2012..The rational and well-coordinated application of these tools, together with improved chemotherapeutic options, will hopefully further improve treatment success in the near future...
[Perspective of cutaneous lymphoma reserach]Reinhard Dummer
Dermatologische Klinik, Universitatsspital Zurich, Schweiz
J Dtsch Dermatol Ges 4:492-5. 2006..The new WHO/EORTC classification definitely will facilitate a more detailed investigation of the various subtypes...
Psoriasis triggered by toll-like receptor 7 agonist imiquimod in the presence of dermal plasmacytoid dendritic cell precursorsMichel Gilliet
Department of Dermatology, University Hospital of Zurich, Zurich, Switzerland
Arch Dermatol 140:1490-5. 2004..It has been proposed that the innate immune system plays a central role in driving the autoimmune T-cell cascade leading to psoriasis; however, there is no direct evidence for this...
Standard and experimental therapy in cutaneous T-cell lymphomasReinhard Dummer
Department of Dermatology, University Hospital of Zurich, Zurich, Switzerland
J Cutan Pathol 33:52-7. 2006..Evidence-based treatment recommendation exists but is hampered by the lack of large multicenter randomized trials...
Skin problems associated with pegylated liposomal doxorubicin-more than palmoplantar erythrodysesthesia syndromeJoanna Mangana
Department of Dermatology, University Hospital of Zurich, Gloriastrasse 31, Zurich, Switzerland
Eur J Dermatol 18:566-70. 2008..Pegylated liposomal doxorubicin induces various skin reactions including palmoplantar erythrodysesthesia syndrome. However, the exact clinical presentation might depend on pre-existing skin diseases...
Prevalence of Merkel cell polyomavirus among Swiss Merkel cell carcinoma patientsJoanna Mangana
Department of Dermatology, University Hospital of Zurich, Zurich, Switzerland
Dermatology 221:184-8. 2010..Recently, the clonal integration of a newly identified polyomavirus called Merkel cell polyomavirus (MCPyV) was reported in up to 80% of MCC tissue. Here we report the incidence rate of MCPyV in MCC patients in Switzerland...
T cell-mediated acute localized exanthematous pustulosis caused by finasterideSandra Tresch
Department of Dermatology, University Hospital Zurich, Zurich, Switzerland
J Allergy Clin Immunol 129:589-94. 2012..Within 4 weeks after withdrawal of finasteride, the rash resolved without any specific therapy. Transient discrete residual hyperpigmentation and scaling were present. The patient refused an oral provocation challenge...
EORTC, ISCL, and USCLC consensus recommendations for the treatment of primary cutaneous CD30-positive lymphoproliferative disorders: lymphomatoid papulosis and primary cutaneous anaplastic large-cell lymphomaWerner Kempf
Department of Dermatology, University Hospital Zurich, Zurich, Switzerland
Blood 118:4024-35. 2011..The recommendations represent the state-of-the-art management of CD30(+) LPDs and include definitions for clinical endpoints as well as response criteria for future clinical trials in CD30(+) LPDs...
Internet based health promotion campaign against skin cancer - Results of www.skincheck.ch in SwitzerlandMarjam Jeanette Barysch
Department of Dermatology, University Hospital of Zurich, CH 8091 Zurich, Switzerland
Eur J Dermatol 20:109-14. 2010..We conclude that internet-based, interactive, educational programs, in addition to existing health promotion campaigns, can enhance public participation in the middle aged male population in skin cancer prevention...
T-cell clonality assays: how do they compare?Antonio Cozzio
Department of Dermatology, Zurich University Hospital, Zurich, Swizerland
J Invest Dermatol 128:771-3. 2008..The resulting genetic heterogeneity may ultimately lead to subclones in the formerly monoclonal population of tumor cells...
Primary cutaneous B-cell lymphomasWerner Kempf
Department of Dermatology, University Hospital Zurich, Switzerland
J Dtsch Dermatol Ges 10:12-22; quiz 23. 2012..Clinico-pathologic correlation, histology with immunohistochemical profile and genotyping as well as staging examinations are crucial diagnostic elements in the work-up of CBCL...
Similar MLL-associated leukemias arising from self-renewing stem cells and short-lived myeloid progenitorsAntonio Cozzio
Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA
Genes Dev 17:3029-35. 2003....
MLL-GAS7 transforms multipotent hematopoietic progenitors and induces mixed lineage leukemias in miceChi Wai So
Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA
Cancer Cell 3:161-71. 2003..This experimental modeling of ABL in mice highlights its origin from multipotential progenitors that arrest at a bipotential stage specifically targeted or induced by MLL oncogenes...
Varicella-zoster virus infection of human neural cells in vivoArmin Baiker
Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA
Proc Natl Acad Sci U S A 101:10792-7. 2004..The chimeric nonobese diabetic severe combined immunodeficient mouse model may be useful for investigating other neurotropic human viruses...
Flt3 ligand regulates dendritic cell development from Flt3+ lymphoid and myeloid-committed progenitors to Flt3+ dendritic cells in vivoHolger Karsunky
Institute for Research in Biomedicine IRB, Via Vincenzo Vela 6, CH 6500 Bellinzona, Switzerland
J Exp Med 198:305-13. 2003....
