Martine A Collart

Summary

Affiliation: University of Geneva
Country: Switzerland

Publications

  1. pmc Not4 E3 ligase contributes to proteasome assembly and functional integrity in part through Ecm29
    Olesya O Panasenko
    Department of Microbiology and Molecular Medicine, University of Geneva, Faculty of Medicine, Geneva, Switzerland
    Mol Cell Biol 31:1610-23. 2011
  2. pmc The CCR4-NOT complex physically and functionally interacts with TRAMP and the nuclear exosome
    Nowel Azzouz
    Department of Microbiology and Molecular Medicine, Faculty of Medicine, University of Geneva, Geneva, Switzerland
    PLoS ONE 4:e6760. 2009
  3. doi request reprint The Not3/5 subunit of the Ccr4-Not complex: a central regulator of gene expression that integrates signals between the cytoplasm and the nucleus in eukaryotic cells
    Martine A Collart
    Dpt of Microbiology and Molecular Medicine, Faculty of Medicine, University of Geneva, 1 rue Michel Servet, 1211 Geneve 4, Switzerland
    Cell Signal 25:743-51. 2013
  4. doi request reprint The Ccr4--not complex
    Martine A Collart
    Dpt Microbiology and Molecular Medicine, Faculty of Medicine, University of Geneva, 1 rue Michel Servet, 1211 Geneva 4, Switzerland
    Gene 492:42-53. 2012
  5. pmc The Ccr4-not complex regulates Skn7 through Srb10 kinase
    Eve Lenssen
    Department of Microbiology and Molecular Medicine, University of Geneva Medical School, CMU, 1 rue Michel Servet, 1211 Geneva 4, Switzerland
    Eukaryot Cell 6:2251-9. 2007
  6. ncbi request reprint The yeast Ccr4-Not complex controls ubiquitination of the nascent-associated polypeptide (NAC-EGD) complex
    Olesya Panasenko
    Department of Microbiology and Molecular Medicine, University of Geneva Medical School, 1211 Geneva 4, Switzerland
    J Biol Chem 281:31389-98. 2006
  7. pmc Specific roles for the Ccr4-Not complex subunits in expression of the genome
    Nowel Azzouz
    Department of Microbiology and Molecular Medicine, Faculty of Medicine, University of Geneva, Geneva 4, Switzerland
    RNA 15:377-83. 2009
  8. pmc The Ccr4-Not complex independently controls both Msn2-dependent transcriptional activation--via a newly identified Glc7/Bud14 type I protein phosphatase module--and TFIID promoter distribution
    Eve Lenssen
    Département de Microbiologie et Médecine Moléculaire, CMU, 1 rue Michel Servet, 1211 Geneva 4, Switzerland
    Mol Cell Biol 25:488-98. 2005
  9. pmc The Ccr4-not complex and yTAF1 (yTaf(II)130p/yTaf(II)145p) show physical and functional interactions
    Cécile Deluen
    Departement de Biochimie Medicale, CMU, 1211 Geneva 4, Switzerland
    Mol Cell Biol 22:6735-49. 2002
  10. pmc Ribosome association and stability of the nascent polypeptide-associated complex is dependent upon its own ubiquitination
    Olesya O Panasenko
    Swiss Institute for Bioinformatics, University of Geneva, 1211 Geneva 4, Switzerland
    Genetics 181:447-60. 2009

Collaborators

Detail Information

Publications17

  1. pmc Not4 E3 ligase contributes to proteasome assembly and functional integrity in part through Ecm29
    Olesya O Panasenko
    Department of Microbiology and Molecular Medicine, University of Geneva, Faculty of Medicine, Geneva, Switzerland
    Mol Cell Biol 31:1610-23. 2011
    ..In the absence of Not4, Ecm29 interacts less well with the proteasome and becomes ubiquitinated and degraded. Our results characterize Ecm29 as a proteasome chaperone whose appropriate interaction with the proteasome requires Not4...
  2. pmc The CCR4-NOT complex physically and functionally interacts with TRAMP and the nuclear exosome
    Nowel Azzouz
    Department of Microbiology and Molecular Medicine, Faculty of Medicine, University of Geneva, Geneva, Switzerland
    PLoS ONE 4:e6760. 2009
    ..However, there has been no evidence so far that this complex is important for RNA degradation in the nucleus...
  3. doi request reprint The Not3/5 subunit of the Ccr4-Not complex: a central regulator of gene expression that integrates signals between the cytoplasm and the nucleus in eukaryotic cells
    Martine A Collart
    Dpt of Microbiology and Molecular Medicine, Faculty of Medicine, University of Geneva, 1 rue Michel Servet, 1211 Geneve 4, Switzerland
    Cell Signal 25:743-51. 2013
    ..This review will summarize recent evidence designing the Not3/5 module of the Ccr4-Not complex as a functional module involved in coordination of the regulation of gene expression between the nucleus and the cytoplasm...
  4. doi request reprint The Ccr4--not complex
    Martine A Collart
    Dpt Microbiology and Molecular Medicine, Faculty of Medicine, University of Geneva, 1 rue Michel Servet, 1211 Geneva 4, Switzerland
    Gene 492:42-53. 2012
    ..Finally, based upon our current state of knowledge, we will propose a model to explain how one complex can provide such multi-functionality. This model suggests that the Ccr4-Not complex might function as a "chaperone platform"...
  5. pmc The Ccr4-not complex regulates Skn7 through Srb10 kinase
    Eve Lenssen
    Department of Microbiology and Molecular Medicine, University of Geneva Medical School, CMU, 1 rue Michel Servet, 1211 Geneva 4, Switzerland
    Eukaryot Cell 6:2251-9. 2007
    ..These results reveal a critical role for the Ccr4-Not complex in the mechanism of activation of Skn7 that is dependent upon the Srb10 kinase...
  6. ncbi request reprint The yeast Ccr4-Not complex controls ubiquitination of the nascent-associated polypeptide (NAC-EGD) complex
    Olesya Panasenko
    Department of Microbiology and Molecular Medicine, University of Geneva Medical School, 1211 Geneva 4, Switzerland
    J Biol Chem 281:31389-98. 2006
    ..Taken together our results reveal that the EGD ribosome-associated complex is ubiquitinated in a regulated manner, and they show a new role for the Ccr4-Not complex in this ubiquitination...
  7. pmc Specific roles for the Ccr4-Not complex subunits in expression of the genome
    Nowel Azzouz
    Department of Microbiology and Molecular Medicine, Faculty of Medicine, University of Geneva, Geneva 4, Switzerland
    RNA 15:377-83. 2009
    ..From the study of only two different growth conditions, revealing an impact of the Ccr4-Not complex on more than 85% of all studied genes, we can infer that the Ccr4-Not complex is important for expression of most of the yeast genome...
  8. pmc The Ccr4-Not complex independently controls both Msn2-dependent transcriptional activation--via a newly identified Glc7/Bud14 type I protein phosphatase module--and TFIID promoter distribution
    Eve Lenssen
    Département de Microbiologie et Médecine Moléculaire, CMU, 1 rue Michel Servet, 1211 Geneva 4, Switzerland
    Mol Cell Biol 25:488-98. 2005
    ..Thus, increased activity of STRE genes in ccr4-not mutants may result from both altered general distribution of TFIID and unscheduled activation of Msn2...
  9. pmc The Ccr4-not complex and yTAF1 (yTaf(II)130p/yTaf(II)145p) show physical and functional interactions
    Cécile Deluen
    Departement de Biochimie Medicale, CMU, 1211 Geneva 4, Switzerland
    Mol Cell Biol 22:6735-49. 2002
    ....
  10. pmc Ribosome association and stability of the nascent polypeptide-associated complex is dependent upon its own ubiquitination
    Olesya O Panasenko
    Swiss Institute for Bioinformatics, University of Geneva, 1211 Geneva 4, Switzerland
    Genetics 181:447-60. 2009
    ..Finally, our study demonstrated an interaction of EGD/NAC with the proteasome and revealed the importance of the Not4p E3 ligase, responsible for EGD/NAC ubiquitination, in this association...
  11. pmc A SAGA-independent function of SPT3 mediates transcriptional deregulation in a mutant of the Ccr4-not complex in Saccharomyces cerevisiae
    Nicole James
    Department of Microbiology and Molecular Medicine, University of Geneva Medical School, Geneva 1211, Switzerland
    Genetics 177:123-35. 2007
    ..Taken together, our results provide a new view of the Spt3 protein by identifying a SAGA-independent function of this protein that is functionally linked to the Ccr4-Not complex...
  12. ncbi request reprint Interaction between Not1p, a component of the Ccr4-not complex, a global regulator of transcription, and Dhh1p, a putative RNA helicase
    Laurent Maillet
    Department of Medical Biochemistry, University of Geneva Medical School, 1 rue Michel Servet, 1211 Geneva 4, Switzerland
    J Biol Chem 277:2835-42. 2002
    ....
  13. pmc The dual control of TFIIB recruitment by NC2 is gene specific
    Patrick Masson
    Department of Microbiology and Molecular Medicine, CMU, 1 rue Michel Servet 1211, Geneva 4, Switzerland
    Nucleic Acids Res 36:539-49. 2008
    ..This study demonstrates an important positive role of NC2 for formation of the pre-initiation complex on promoters, under normal conditions through control of TFIIB, or upon activation by stress via control of TBP...
  14. doi request reprint Presence of Not5 and ubiquitinated Rps7A in polysome fractions depends upon the Not4 E3 ligase
    Olesya O Panasenko
    Department of Microbiology and Molecular Medicine, University of Geneva, Faculty of Medicine, 1 rue Michel Servet, 1211 Geneva 4, Switzerland
    Mol Microbiol 83:640-53. 2012
    ..These results lead us to suggest that Not4 contributes to normal polysome levels and is important for cellular protein solubility maybe in part by ubiquitination of Rps7A...
  15. ncbi request reprint The eukaryotic Ccr4-not complex: a regulatory platform integrating mRNA metabolism with cellular signaling pathways?
    Martine A Collart
    Department of Medical Biochemistry, CMU, 1 rue Michel Servet, 1211 Geneva 4, Switzerland
    Prog Nucleic Acid Res Mol Biol 77:289-322. 2004
  16. ncbi request reprint LKB1 interacts with and phosphorylates PTEN: a functional link between two proteins involved in cancer predisposing syndromes
    Hamid Mehenni
    Departement de Biologie Cellulaire, Universite de Geneve, 1211 Geneve 4, Switzerland
    Hum Mol Genet 14:2209-19. 2005
    ....
  17. doi request reprint The Not4 E3 ligase and CCR4 deadenylase play distinct roles in protein quality control
    David Halter
    Department of Microbiology and Molecular Medicine, Faculty of Medicine, Institute of Genetics and Genomics of Geneva, University of Geneva, Geneva, Switzerland
    PLoS ONE 9:e86218. 2014
    ..We concluded that Not4 plays a role in protein quality control independently of the Ccr4 deadenylase, and that it is involved in clearance of aberrant proteins at least in part via the proteasome. ..