Research Topics
Genomes and Genes | Martine A CollartSummaryAffiliation: University of Geneva Country: Switzerland Publications
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Publications
Not4 E3 ligase contributes to proteasome assembly and functional integrity in part through Ecm29Olesya O Panasenko
Department of Microbiology and Molecular Medicine, University of Geneva, Faculty of Medicine, Geneva, Switzerland
Mol Cell Biol 31:1610-23. 2011..In the absence of Not4, Ecm29 interacts less well with the proteasome and becomes ubiquitinated and degraded. Our results characterize Ecm29 as a proteasome chaperone whose appropriate interaction with the proteasome requires Not4...
The Not3/5 subunit of the Ccr4-Not complex: a central regulator of gene expression that integrates signals between the cytoplasm and the nucleus in eukaryotic cellsMartine A Collart
Dpt of Microbiology and Molecular Medicine, Faculty of Medicine, University of Geneva, 1 rue Michel Servet, 1211 Geneve 4, Switzerland
Cell Signal 25:743-51. 2013..This review will summarize recent evidence designing the Not3/5 module of the Ccr4-Not complex as a functional module involved in coordination of the regulation of gene expression between the nucleus and the cytoplasm...
The Ccr4--not complexMartine A Collart
Dpt Microbiology and Molecular Medicine, Faculty of Medicine, University of Geneva, 1 rue Michel Servet, 1211 Geneva 4, Switzerland
Gene 492:42-53. 2012..This model suggests that the Ccr4-Not complex might function as a "chaperone platform"...
Presence of Not5 and ubiquitinated Rps7A in polysome fractions depends upon the Not4 E3 ligaseOlesya O Panasenko
Department of Microbiology and Molecular Medicine, University of Geneva, Faculty of Medicine, 1 rue Michel Servet, 1211 Geneva 4, Switzerland
Mol Microbiol 83:640-53. 2012..These results lead us to suggest that Not4 contributes to normal polysome levels and is important for cellular protein solubility maybe in part by ubiquitination of Rps7A...
Ribosome association and stability of the nascent polypeptide-associated complex is dependent upon its own ubiquitinationOlesya O Panasenko
Swiss Institute for Bioinformatics, University of Geneva, 1211 Geneva 4, Switzerland
Genetics 181:447-60. 2009..Finally, our study demonstrated an interaction of EGD/NAC with the proteasome and revealed the importance of the Not4p E3 ligase, responsible for EGD/NAC ubiquitination, in this association...
