Matthias Chiquet

Summary

Affiliation: University of Bern
Country: Switzerland

Publications

  1. ncbi How do fibroblasts translate mechanical signals into changes in extracellular matrix production?
    Matthias Chiquet
    ITI Research Institute for Dental and Skeletal Biology, University of Bern, P O Box 54, Switzerland
    Matrix Biol 22:73-80. 2003
  2. ncbi Gene regulation by mechanotransduction in fibroblasts
    Matthias Chiquet
    ITI Research Institute for Dental and Skeletal Biology, University of Bern, Murtenstrasse 35, CH 3010 Bern, Switzerland
    Appl Physiol Nutr Metab 32:967-73. 2007
  3. ncbi Induction of tenascin-C by cyclic tensile strain versus growth factors: distinct contributions by Rho/ROCK and MAPK signaling pathways
    Matthias Chiquet
    ITI Research Institute for Dental and Skeletal Biology, University of Bern, Murtenstrasse 35, P O Box 54, CH 3010 Bern, Switzerland
    Biochim Biophys Acta 1693:193-204. 2004
  4. ncbi Role of RhoA/ROCK-dependent actin contractility in the induction of tenascin-C by cyclic tensile strain
    Ana Sarasa-Renedo
    ITI Research Institute for Dental and Skeletal Biology, University of Bern, Murtenstrasse 35, P O Box 54, Switzerland
    Exp Cell Res 312:1361-70. 2006
  5. ncbi Cleavage of extracellular matrix in periodontitis: gingipains differentially affect cell adhesion activities of fibronectin and tenascin-C
    Sabrina Ruggiero
    Department of Orthodontics and Dentofacial Orthopedics, University of Bern, Switzerland
    Biochim Biophys Acta 1832:517-26. 2013
  6. ncbi Tensile stress-dependent collagen XII and fibronectin production by fibroblasts requires separate pathways
    Martin Fluck
    M E Müller Institute for Biomechanics, University of Bern, Bern, Switzerland
    Biochim Biophys Acta 1593:239-48. 2003
  7. doi From mechanotransduction to extracellular matrix gene expression in fibroblasts
    Matthias Chiquet
    Friedrich Miescher Institute for Biomedical Research, Novartis Research Foundation, Maulbeerstrasse 66, CH 4058, Basel, Switzerland
    Biochim Biophys Acta 1793:911-20. 2009
  8. doi Electron microscopy of high pressure frozen samples: bridging the gap between cellular ultrastructure and atomic resolution
    Daniel Studer
    Institute for Anatomy, University of Bern, Baltzerstr 2, 3000, Bern 9, Switzerland
    Histochem Cell Biol 130:877-89. 2008
  9. ncbi Transient induction of cyclin A in loaded chicken skeletal muscle
    Martin Fluck
    Dept of Anatomy, Univ of Bern, Buhlstrasse 26, 3000 Bern 9, Switzerland
    J Appl Physiol (1985) 95:1664-71. 2003
  10. doi Cell shape-dependent early responses of fibroblasts to cyclic strain
    Neha Gadhari
    Department of Orthodontics and Dentofacial Orthopaedics, University of Bern, Switzerland
    Biochim Biophys Acta 1833:3415-25. 2013

Collaborators

Detail Information

Publications17

  1. ncbi How do fibroblasts translate mechanical signals into changes in extracellular matrix production?
    Matthias Chiquet
    ITI Research Institute for Dental and Skeletal Biology, University of Bern, P O Box 54, Switzerland
    Matrix Biol 22:73-80. 2003
    ..In the case of the tenascin-C gene, different promoter elements might be involved in induction by cyclic stretch. Thus, different mechanical signals seem to regulate distinct ECM genes in complex ways...
  2. ncbi Gene regulation by mechanotransduction in fibroblasts
    Matthias Chiquet
    ITI Research Institute for Dental and Skeletal Biology, University of Bern, Murtenstrasse 35, CH 3010 Bern, Switzerland
    Appl Physiol Nutr Metab 32:967-73. 2007
    ..Thus, RhoA/ROCK-controlled actin dynamics are required for the induction of specific ECM genes by mechanical stress. These findings have implications for the understanding of regeneration and for tissue engineering...
  3. ncbi Induction of tenascin-C by cyclic tensile strain versus growth factors: distinct contributions by Rho/ROCK and MAPK signaling pathways
    Matthias Chiquet
    ITI Research Institute for Dental and Skeletal Biology, University of Bern, Murtenstrasse 35, P O Box 54, CH 3010 Bern, Switzerland
    Biochim Biophys Acta 1693:193-204. 2004
    ..The data suggest that regulation of tenascin-C in fibroblasts by cyclic strain occurs independently from soluble mediators and MAPK pathways; however, it requires Rho/ROCK signaling...
  4. ncbi Role of RhoA/ROCK-dependent actin contractility in the induction of tenascin-C by cyclic tensile strain
    Ana Sarasa-Renedo
    ITI Research Institute for Dental and Skeletal Biology, University of Bern, Murtenstrasse 35, P O Box 54, Switzerland
    Exp Cell Res 312:1361-70. 2006
    ..Previous RhoA/ROCK activation, either by chemical or mechanical signals, might render fibroblasts more sensitive to external tensile stress, e.g., during wound healing...
  5. ncbi Cleavage of extracellular matrix in periodontitis: gingipains differentially affect cell adhesion activities of fibronectin and tenascin-C
    Sabrina Ruggiero
    Department of Orthodontics and Dentofacial Orthopedics, University of Bern, Switzerland
    Biochim Biophys Acta 1832:517-26. 2013
    ..We conclude that cleavage by gingipains directly affects the biological activity of both fibronectin and tenascin-C in a manner that might lead to increased cell detachment and loss during periodontal disease...
  6. ncbi Tensile stress-dependent collagen XII and fibronectin production by fibroblasts requires separate pathways
    Martin Fluck
    M E Müller Institute for Biomechanics, University of Bern, Bern, Switzerland
    Biochim Biophys Acta 1593:239-48. 2003
    ....
  7. doi From mechanotransduction to extracellular matrix gene expression in fibroblasts
    Matthias Chiquet
    Friedrich Miescher Institute for Biomedical Research, Novartis Research Foundation, Maulbeerstrasse 66, CH 4058, Basel, Switzerland
    Biochim Biophys Acta 1793:911-20. 2009
    ..As assembly lines for diverse signaling pathways, matrix adhesion contacts are now recognized as the major sites of crosstalk between mechanical and chemical stimuli, with important consequences for cell growth and differentiation...
  8. doi Electron microscopy of high pressure frozen samples: bridging the gap between cellular ultrastructure and atomic resolution
    Daniel Studer
    Institute for Anatomy, University of Bern, Baltzerstr 2, 3000, Bern 9, Switzerland
    Histochem Cell Biol 130:877-89. 2008
    ..High pressure freezing of tissue is the base which may lead to precise models of macromolecular assemblies in situ, and thus to a better understanding of the function of complex cellular structures...
  9. ncbi Transient induction of cyclin A in loaded chicken skeletal muscle
    Martin Fluck
    Dept of Anatomy, Univ of Bern, Buhlstrasse 26, 3000 Bern 9, Switzerland
    J Appl Physiol (1985) 95:1664-71. 2003
    ....
  10. doi Cell shape-dependent early responses of fibroblasts to cyclic strain
    Neha Gadhari
    Department of Orthodontics and Dentofacial Orthopaedics, University of Bern, Switzerland
    Biochim Biophys Acta 1833:3415-25. 2013
    ..We conclude that integrin-mediated responses to external mechanical strain are differentially modulated in cells that have the same spreading area but different geometries, and do not only depend on mere cell size. ..
  11. doi Tenascin-C and matrix metalloproteinase-9 levels in crevicular fluid of teeth and implants
    Ceyda Ozçakir-Tomruk
    Department of Prosthodontics, School of Dentistry, University of Bern, Bern, Switzerland
    Clin Implant Dent Relat Res 14:672-81. 2012
    ..The role of and interaction between bacterial infection and biomechanical impact in the development of peri-implant inflammatory processes is not clear...
  12. doi Identification of a fibronectin interaction site in the extracellular matrix protein ameloblastin
    Michael Beyeler
    Department of Clinical Research, University of Bern, Bern, Switzerland
    Exp Cell Res 316:1202-12. 2010
    ..The recruited fibronectin should then promote cell adhesion on the implant surface, thereby accelerating osseointegration of the implant...
  13. ncbi Reloading of atrophied rat soleus muscle induces tenascin-C expression around damaged muscle fibers
    Martin Fluck
    M E Müller Institute for Biomechanics, Department of Anatomy, University of Bern, 3000 Bern 9, Switzerland
    Am J Physiol Regul Integr Comp Physiol 284:R792-801. 2003
    ..The observations demonstrate that an unaccustomed increase of rat soleus muscle loading causes modification of the basement membrane of damaged muscle fibers through ectopic endomysial expression of tenascin-C...
  14. doi Tenascin-C induction by cyclic strain requires integrin-linked kinase
    Silke Maier
    Friedrich Miescher Institute for Biomedical Research, Novartis Research Foundation, CH 4058 Basel, Switzerland
    Biochim Biophys Acta 1783:1150-62. 2008
    ..Our results indicate that ILK is selectively required for the induction of specific genes by mechanical stimulation via RhoA-mediated pathways...
  15. ncbi Ectopic expression of tenascin-C
    Matthias Chiquet
    J Cell Sci 116:3851; author reply 3851-3; discussion 3853. 2003
  16. ncbi Tenascins: regulation and putative functions during pathological stress
    Ruth Chiquet-Ehrismann
    Friedrich Miescher Institute, Novartis Research Foundation, Maulbeerstrasse 66, CH 4058 Basel, Switzerland
    J Pathol 200:488-99. 2003
    ....
  17. ncbi Collagen XII interacts with avian tenascin-X through its NC3 domain
    Guido Veit
    Center for Biochemistry, Department of Dermatology, Medical Faculty, University of Cologne, D 50931 Cologne, Germany, and Shriners Hospital for Children Research Center, Portland, Oregon 97239, USA
    J Biol Chem 281:27461-70. 2006
    ..On the ultrastructural level, detection of collagen XII and tenascin-X by immunogold labeling confirmed this finding...