T Chevalley

Summary

Affiliation: University Hospital
Country: Switzerland

Publications

  1. doi Fracture history of healthy premenopausal women is associated with a reduction of cortical microstructural components at the distal radius
    T Chevalley
    Division of Bone Diseases, University Hospitals and Faculty of Medicine, Geneva, Switzerland
    Bone 55:377-83. 2013
  2. doi Fractures in healthy females followed from childhood to early adulthood are associated with later menarcheal age and with impaired bone microstructure at peak bone mass
    T Chevalley
    Division of Bone Diseases, Geneva University Hospitals and Faculty of Medicine, Rue Gabrielle Perret Gentil 4, CH 1211 Geneva 14, Switzerland
    J Clin Endocrinol Metab 97:4174-81. 2012
  3. ncbi High-protein intake enhances the positive impact of physical activity on BMC in prepubertal boys
    Thierry Chevalley
    Division of Bone Diseases WHO Collaborating Centre for Osteoporosis Prevention, Department of Rehabilitation and Geriatrics, University Hospitals of Geneva, Geneva, Switzerland
    J Bone Miner Res 23:131-42. 2008
  4. doi Influence of age at menarche on forearm bone microstructure in healthy young women
    Thierry Chevalley
    Division of Bone Diseases, Department of Rehabilitation and Geriatrics, Geneva University Hospitals and Faculty of Medicine, Rue Micheli du Crest 24, Geneva 14, Switzerland
    J Clin Endocrinol Metab 93:2594-601. 2008
  5. doi Deleterious effect of late menarche on distal tibia microstructure in healthy 20-year-old and premenopausal middle-aged women
    Thierry Chevalley
    Division of Bone Diseases, Department of Rehabilitation and Geriatrics, Geneva University Hospitals and Faculty of Medicine, Geneva, Switzerland
    J Bone Miner Res 24:144-52. 2009
  6. doi The influence of pubertal timing on bone mass acquisition: a predetermined trajectory detectable five years before menarche
    T Chevalley
    Division of Bone Diseases, Department of Rehabilitation and Geriatrics, Geneva University Hospitals and Faculty of Medicine, Rue Gabrielle Perret Gentil 4, CH 1211 Geneva 14, Switzerland
    J Clin Endocrinol Metab 94:3424-31. 2009
  7. doi Early serum IGF-I response to oral protein supplements in elderly women with a recent hip fracture
    Thierry Chevalley
    Division of Bone Diseases, WHO Collaborating Centre for Osteoporosis and Bone Diseases, Department of Rehabilitation and Geriatrics, Geneva University Hospitals and Faculty of Medicine, University of Geneva, CH 1211 Geneva 14, Switzerland
    Clin Nutr 29:78-83. 2010
  8. ncbi [General trend of hip fractures]
    Thierry Chevalley
    Service des maladies osseuses, Département des spécialités de médecine, HUG, Geneve 14
    Rev Med Suisse 7:1294-8. 2011
  9. doi Fractures during childhood and adolescence in healthy boys: relation with bone mass, microstructure, and strength
    T Chevalley
    Division of Bone Diseases, University Hospitals and Faculty of Medicine, CH 1211 Geneva 14, Switzerland
    J Clin Endocrinol Metab 96:3134-42. 2011
  10. ncbi [Incidence of hip fracture: reversal of a secular trend]
    Thierry Chevalley
    Service des maladies osseuses, Centre collaborateur de I OMS pour la prevention de l ostéoporose, Département de réhabilitation et gériatrie, HUG, Geneve
    Rev Med Suisse 3:1528-30, 1532-3. 2007

Collaborators

Detail Information

Publications27

  1. doi Fracture history of healthy premenopausal women is associated with a reduction of cortical microstructural components at the distal radius
    T Chevalley
    Division of Bone Diseases, University Hospitals and Faculty of Medicine, Geneva, Switzerland
    Bone 55:377-83. 2013
    ..The objective of this study is to determine in healthy premenopausal women with a history of fracture which bone structural components of the distal radius are the most closely associated with a risk of fracture...
  2. doi Fractures in healthy females followed from childhood to early adulthood are associated with later menarcheal age and with impaired bone microstructure at peak bone mass
    T Chevalley
    Division of Bone Diseases, Geneva University Hospitals and Faculty of Medicine, Rue Gabrielle Perret Gentil 4, CH 1211 Geneva 14, Switzerland
    J Clin Endocrinol Metab 97:4174-81. 2012
    ..Considering the importance of pubertal timing in bone development, we also quantified the fracture risk related to later menarcheal age (MENA)...
  3. ncbi High-protein intake enhances the positive impact of physical activity on BMC in prepubertal boys
    Thierry Chevalley
    Division of Bone Diseases WHO Collaborating Centre for Osteoporosis Prevention, Department of Rehabilitation and Geriatrics, University Hospitals of Geneva, Geneva, Switzerland
    J Bone Miner Res 23:131-42. 2008
    ..In 232 healthy prepubertal boys, increased physical activity was associated with greater BMC at both axial and appendicular sites under high-protein intake...
  4. doi Influence of age at menarche on forearm bone microstructure in healthy young women
    Thierry Chevalley
    Division of Bone Diseases, Department of Rehabilitation and Geriatrics, Geneva University Hospitals and Faculty of Medicine, Rue Micheli du Crest 24, Geneva 14, Switzerland
    J Clin Endocrinol Metab 93:2594-601. 2008
    ..The influence of menarcheal age (MENA) on peak bone mass, cortical, and trabecular microstructure was studied in 124 healthy women aged 20.4 +/- 0.6 (sd) yr...
  5. doi Deleterious effect of late menarche on distal tibia microstructure in healthy 20-year-old and premenopausal middle-aged women
    Thierry Chevalley
    Division of Bone Diseases, Department of Rehabilitation and Geriatrics, Geneva University Hospitals and Faculty of Medicine, Geneva, Switzerland
    J Bone Miner Res 24:144-52. 2009
    ..Alterations in both bone mineral mass and microstructural components may explain the increased risk of fragility fractures associated with later menarcheal age...
  6. doi The influence of pubertal timing on bone mass acquisition: a predetermined trajectory detectable five years before menarche
    T Chevalley
    Division of Bone Diseases, Department of Rehabilitation and Geriatrics, Geneva University Hospitals and Faculty of Medicine, Rue Gabrielle Perret Gentil 4, CH 1211 Geneva 14, Switzerland
    J Clin Endocrinol Metab 94:3424-31. 2009
    ..It is associated with low peak bone mass (PBM). Like PBM, MENA is under strong genetic influence. We hypothesized that MENA-related bone mass differences could be predetermined before puberty...
  7. doi Early serum IGF-I response to oral protein supplements in elderly women with a recent hip fracture
    Thierry Chevalley
    Division of Bone Diseases, WHO Collaborating Centre for Osteoporosis and Bone Diseases, Department of Rehabilitation and Geriatrics, Geneva University Hospitals and Faculty of Medicine, University of Geneva, CH 1211 Geneva 14, Switzerland
    Clin Nutr 29:78-83. 2010
    ..Elevation of circulating IGF-I in response to a daily oral supplement of 20 g of casein was observed after 6 months. This study determined if the response to casein as compared to whey protein can be observed as early as after one week...
  8. ncbi [General trend of hip fractures]
    Thierry Chevalley
    Service des maladies osseuses, Département des spécialités de médecine, HUG, Geneve 14
    Rev Med Suisse 7:1294-8. 2011
    ..Furthermore, age-adjusted hospitalizations in Switzerland for major non-hip osteoporotic fractures have continued to increase these last years...
  9. doi Fractures during childhood and adolescence in healthy boys: relation with bone mass, microstructure, and strength
    T Chevalley
    Division of Bone Diseases, University Hospitals and Faculty of Medicine, CH 1211 Geneva 14, Switzerland
    J Clin Endocrinol Metab 96:3134-42. 2011
    ..In healthy boys, fractures result from trauma of various severity, suggesting contribution of an intrinsic biomechanical fragility...
  10. ncbi [Incidence of hip fracture: reversal of a secular trend]
    Thierry Chevalley
    Service des maladies osseuses, Centre collaborateur de I OMS pour la prevention de l ostéoporose, Département de réhabilitation et gériatrie, HUG, Geneve
    Rev Med Suisse 3:1528-30, 1532-3. 2007
    ..4%/year in women (p = 0.021), but remained stable in men (+0.5%/year, p = 0.66), suggesting a reversal of the previously observed secular trend...
  11. ncbi Incidence of hip fracture over a 10-year period (1991-2000): reversal of a secular trend
    T Chevalley
    Service of Bone Diseases and Geriatric Evaluation Unit, Department of Rehabilitation and Geriatrics, University Hospitals of Geneva, CH 1211 Geneva 14, Switzerland
    Bone 40:1284-9. 2007
    ..We specifically examined secular changes in the incidence of hip fracture in women and men aged 50 years and over in the well-defined area of Geneva, Switzerland...
  12. ncbi Skeletal site selectivity in the effects of calcium supplementation on areal bone mineral density gain: a randomized, double-blind, placebo-controlled trial in prepubertal boys
    T Chevalley
    Service of Bone Diseases, Department of Rehabilitation and Geriatrics, University Hospitals of Geneva, CH 1211 Geneva 14, Switzerland
    J Clin Endocrinol Metab 90:3342-9. 2005
    ..Calcium supplementation during childhood and adolescence is considered an early means of preventing osteoporosis in adults. Prepuberty is an opportune time for detecting the benefits of calcium in girls...
  13. ncbi Interaction between calcium intake and menarcheal age on bone mass gain: an eight-year follow-up study from prepuberty to postmenarche
    Thierry Chevalley
    Service of Bone Diseases WHO Collaborating Center for Osteoporosis Prevention, Department of Rehabilitation and Geriatrics, University Hospitals, CH 1211 Geneva 14, Switzerland
    J Clin Endocrinol Metab 90:44-51. 2005
    ..Thus, both determinants of early menarcheal age and high Ca intake may positively interact on bone mineral mass accrual...
  14. ncbi [Protein and calcium consumption, and bone growth]
    Thierry Chevalley
    Service des maladies osseuses Centre collaborateur de l OMS pour la prévention de l ostéoporose Département de réhabilitation et gériatrie HUG
    Rev Med Suisse Romande 124:97-100. 2004
    ..Some nutrients such as calcium and proteins may influence positively the trajectory of bone mass acquisition and therefore increase peak bone mass...
  15. ncbi [Modifying bone mass in child and adolescent: why?]
    Th Chevalley
    Service des maladies osseuses Centre collaborateur de l OMS pour la prévention de l ostéoporose, Bilan de Gériatrie, Département de réhabilitation et gériatrie, Hopitaux Universitaires de Geneve
    Praxis (Bern 1994) 93:415-21. 2004
    ..Physical activity and some nutrients such as calcium and proteins may influence positively the trajectory of bone mass acquisition and therefore increase peak bone mass...
  16. ncbi An osteoporosis clinical pathway for the medical management of patients with low-trauma fracture
    T Chevalley
    Division of Bone Diseases, WHO Collaborating Center for Osteoporosis and Bone Diseases, Department of Internal Medicine, University Hospitals of Geneva, Switzerland
    Osteoporos Int 13:450-5. 2002
    ....
  17. ncbi Evaluation of the age-adjusted incidence of hip fractures between urban and rural areas: the difference is not related to the prevalence of institutions for the elderly
    T Chevalley
    Department of Geriatrics, WHO Collaborating Center for Osteoporosis and Bone Diseases, University Hospital, Geneva, Switzerland
    Osteoporos Int 13:113-8. 2002
    ..Since this difference is increased when patients living at home were analyzed separately, it indicates that the difference between urban and rural areas is not due to a preferential urban location of institutions for the elderly...
  18. pmc Pubertal timing and body mass index gain from birth to maturity in relation with femoral neck BMD and distal tibia microstructure in healthy female subjects
    T Chevalley
    Division of Bone Diseases, Department of Rehabilitation and Geriatrics, Geneva University Hospitals and Faculty of Medicine, Rue Micheli du Crest 24, CH 1211, Geneva 14, Switzerland
    Osteoporos Int 22:2689-98. 2011
    ..This study underscores the importance of pubertal timing in age-related fragility fracture risk...
  19. doi Alterations of bone microstructure and strength in end-stage renal failure
    A Trombetti
    Bone Diseases Service, Department of Internal Medicine Specialties, Geneva University Hospitals and Faculty of Medicine, Rue Gabrielle Perret Gentil 4, 1211, Geneva 14, Switzerland
    Osteoporos Int 24:1721-32. 2013
    ..We observed an alteration of cortical and trabecular bone microstructure and of bone strength and stiffness in ESRD patients...
  20. ncbi Protein intake and bone disorders in the elderly
    R Rizzoli
    Centre Collaborateur de l OMS pour l ostéoporose et les Maladies Osseuses, Departement de Medecine Interne, Hopital Cantonal Universitaire, Geneva, Switzerland
    Joint Bone Spine 68:383-92. 2001
    ..Supplemental protein also significantly reduces the length of inpatient rehabilitation care. These data emphasize the importance of adequate nutrient intake in the prevention and treatment of osteoporotic fractures...
  21. doi Socioeconomic and living conditions are determinants of hip fracture incidence and age occurrence among community-dwelling elderly
    E Guilley
    Centre for Interdisciplinary Gerontology, University of Geneva, Geneva, Switzerland
    Osteoporos Int 22:647-53. 2011
    ..Age at hip fracture also depended of marital status but in a gender-specific way...
  22. doi Long-term HIV infection and antiretroviral therapy are associated with bone microstructure alterations in premenopausal women
    A Calmy
    Division of Infectious Diseases, HIV Unit, Department of Internal Medicine Specialties, Geneva University Hospitals and Faculty of Medicine, Geneva, Switzerland
    Osteoporos Int 24:1843-52. 2013
    ..Premenopausal eumenorrheic HIV-positive women displayed trabecular and cortical microstructure alterations, which could contribute to increased bone fragility in those patients...
  23. ncbi Reversal of the hip fracture secular trend is related to a decrease in the incidence in institution-dwelling elderly women
    E Guilley
    Centre for Interdisciplinary Gerontology, University of Geneva, Geneva, Switzerland
    Osteoporos Int 19:1741-7. 2008
    ..3% per year reduction in the standardized incidence of hip fracture in women but not in men. This decrease was mainly due to changes in the standardized incidence of hip fracture in institution-dwelling women...
  24. ncbi Prevalence of vertebral fracture in oldest old nursing home residents
    A Rodondi
    Division of Bone Diseases, Department of Medical Specialties, Geneva University Hospitals and Faculty of Medicine, CH 1211 Geneva 14, Switzerland
    Osteoporos Int 23:2601-6. 2012
    ..Probably in relation with the prevailing influence of age and medical history of fracture, adding these information into FRAX did not markedly modify fracture probability...
  25. ncbi Protein intake and bone growth
    J P Bonjour
    Division of Bone Diseases, WHO Collaborating Center for Osteoporosis and Bone Diseases, Department of Internal Medicine, University Hospital, Geneva, Switzerland
    Can J Appl Physiol 26:S153-66. 2001
    ..This suggests that, like for the bone response to either the intake of calcium or weight-bearing exercise, the skeleton would be particularly responsive to the protein intake during the years preceding the onset of pubertal maturation...
  26. ncbi Gain in bone mineral mass in prepubertal girls 3.5 years after discontinuation of calcium supplementation: a follow-up study
    J P Bonjour
    Division of Bone Diseases WHO Collaborating Centre for Osteoporosis and Bone Diseases, Department of Internal Medicine, University Hospital, Geneva, Switzerland
    Lancet 358:1208-12. 2001
    ..We now report the results of a follow-up study undertaken more than 3 years after the end of calcium supplementation...
  27. ncbi Arginine increases insulin-like growth factor-I production and collagen synthesis in osteoblast-like cells
    T Chevalley
    WHO Collaborating Center for Osteoporosis and Bone Diseases, Department of Internal Medicine, University Hospital, Geneva, Switzerland
    Bone 23:103-9. 1998
    ..02). In conclusion, Arg stimulated IGF-I production and collagen synthesis in osteoblast-like cells. Thus, Arg may influence bone formation by enhancing local IGF-I production...